iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	PINA
Post-translational Modifications (PTMs)
dbPAF
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	8.70e-10	38.7	36	79

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkC 51
           ++C+vC +gg+    l++C+ C +++H +Cl+++  ++ p+ + wiCp+C
   Q: 36   EYCKVCSDGGD----LLCCDSCPSVYHRTCLSPP-LKSIPKGD-WICPRC 79
           79*********....*******************.*******7.****** PP

Organism

Drosophila melanogaster

Functional Description
(View)

Possible transcription activator.

Protein Sequence
(Fasta)

MSSKRGADPD WKTPGKASKD KRPKTNAKKQ KFRDEEYCKV CSDGGDLLCC DSCPSVYHRT 60
CLSPPLKSIP KGDWICPRCI PLPGKAEKIL SWRWALDRSV ELRTSKGEKR REYFIKWHGM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GTACCGTTTT CTTCTGGCGC GCATTTGACA ATTTCCATTT CAGAATCAGT GATTGCAAAA 60
ACTAAACTCA AATAGCATGT CGTCTAAGAG AGGGGCTGAT CCAGACTGGA AAACACCTGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0010--Activator
KW-0067--ATP-binding
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000953--Chromo/chromo_shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00385--Chromo
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N

SMART

SM00298--CHROMO
SM00487--DEXDc
SM00490--HELICc
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0035327--C:transcriptionally active chromatin
GO:0005524--F:ATP binding
GO:0008026--F:ATP-dependent helicase activity
GO:0003677--F:DNA binding
GO:0004386--F:helicase activity
GO:0031491--F:nucleosome binding
GO:0070615--F:nucleosome-dependent ATPase activity
GO:0008270--F:zinc ion binding
GO:0006333--P:chromatin assembly or disassembly
GO:0042766--P:nucleosome mobilization
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

KEGG

dme:Dmel_CG9594

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000518	Aegilops tauschii	33.40	3.00e-70	259.00
IUUC-Ago-007719	Ashbya gossypii	31.40	1.00e-73	271.00
IUUC-Bci-013603	Botrytis cinerea	32.12	8.00e-67	248.00
IUUC-Cre-022710	Chlamydomonas reinhardtii	29.81	4.00e-54	206.00
IUUC-Cgl-026654	Colletotrichum gloeosporioides	30.68	5.00e-63	235.00
IUUC-Cme-027109	Cyanidioschyzon merolae	36.49	4.00e-78	285.00
IUUC-Dse-031225	Dothistroma septosporum	32.16	6.00e-72	265.00
IUUC-Fox-037667	Fusarium oxysporum	33.33	4.00e-62	232.00
IUUC-Kpa-049261	Komagataella pastoris	32.60	3.00e-70	259.00
IUUC-Mor-057145	Magnaporthe oryzae	32.20	8.00e-68	251.00
IUUC-Mpo-057493	Magnaporthe poae	33.14	6.00e-70	258.00
IUUC-Mtr-057734	Medicago truncatula	32.44	8.00e-69	255.00
IUUC-Mac-064440	Musa acuminata	32.61	3.00e-68	253.00
IUUC-Ncr-068920	Neurospora crassa	31.27	6.00e-67	248.00
IUUC-Ppa-095213	Physcomitrella patens	45.00	0.00e+00	633.00
IUUC-Pte-104217	Pyrenophora teres	30.22	4.00e-63	236.00
IUUC-Ssl-108500	Sclerotinia sclerotiorum	31.63	1.00e-68	254.00
IUUC-Tre-121868	Trichoderma reesei	31.12	1.00e-62	234.00
IUUC-Tvi-122455	Trichoderma virens	31.47	2.00e-60	227.00
IUUC-Tae-123249	Triticum aestivum	33.27	6.00e-71	262.00
IUUC-Tur-126107	Triticum urartu	33.40	3.00e-70	259.00
IUUC-Vda-129884	Verticillium dahliae	33.21	2.00e-71	263.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence