iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mcc-055110

Ensembl Protein ID

ENSMMUP00000002273.3

UniProt Accession

H9ESU1; F7FZW7; H9ESU1_MACMU

Genbank Protein ID

AFE65450.1; AFH28665.1; AFI33222.1

Protein Name

Signal transducing adapter molecule 1

Genbank Nucleotide ID

JSUE03042956; JU471861; JV043151

Gene Name

STAM

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000001700.3	ENSMMUT00000002403.3	ENSMMUP00000002273.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/Alpha-Helix/VHS	2.70e-55	187.1	16	143
UBD/SH3	5.80e-17	62.5	213	265

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/Alpha-Helix/VHS

   S: 1    atselvtsedwelileicdliqetkegakdalralrkrinnknphvalraLtlLdscvsnCgkkfhvevaskdlleelrellknenepk 89
           atse++t+edw lil+icd+++++++g+kd+lr++++r+n+k+phva++aLtlL++cvsnCgk+fh+ev+s+d+++e++++l n+ +pk
   Q: 16   ATSEMNTAEDWGLILDICDKVGQSRTGPKDCLRSIMRRVNHKDPHVAMQALTLLGACVSNCGKIFHLEVCSRDFASEVSNVL-NKGHPK 103
           799*******************************************************************************.9***** PP
   S: 90   vieKlkalivsWadelknepalslivaliktlkeeGlefp 129
           v+eKlkal+v+W+de+kn+p+lsli+a+ik+lke+G++fp
   Q: 104  VCEKLKALMVEWTDEFKNDPQLSLISAMIKNLKEQGVTFP 143
           ***************************************8 PP

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFve 60
           +kv+++yd+ea++d+eLt+k+G++++v+  ++ d +W+kg  e+++  GlfP+nFv+
   Q: 213  RKVRAIYDFEAAEDNELTFKAGEIITVL--DDSDPNWWKG--ETHQGIGLFPSNFVT 265
           699*************************..99********..9************97 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPLFATNPFD QDVEKATSEM NTAEDWGLIL DICDKVGQSR TGPKDCLRSI MRRVNHKDPH 60
VAMQALTLLG ACVSNCGKIF HLEVCSRDFA SEVSNVLNKG HPKVCEKLKA LMVEWTDEFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GATGGGGCAG GCTCGGGGCA CCTTTGGGAC AGGCAGTGCC GAGGTCGCCC AGATTCCCGA 60
CAAGCTCCGC GCGGGGGCTT TCTCGGCTCA GTGCTGTTGC CGCCGCCACC GCCGCTGCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR008942--ENTH_VHS
IPR004152--GAT_dom
IPR001452--SH3_domain
IPR003903--UIM_dom
IPR002014--VHS_dom

PROSITE

PS50002--SH3
PS50330--UIM
PS50179--VHS

Pfam

PF00018--SH3_1
PF02809--UIM
PF00790--VHS

PRINTS

PR00452--SH3DOMAIN

SMART

SM00326--SH3
SM00288--VHS

Gene Ontology

GO:0005622--C:intracellular
GO:0006886--P:intracellular protein transport
GO:1903543--P:positive regulation of exosomal secretion
GO:1903551--P:regulation of extracellular exosome assembly

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002392	Ailuropoda melanoleuca	94.59	0.00e+00	933.00
IUUC-Apl-003463	Anas platyrhynchos	86.93	0.00e+00	873.00
IUUC-Aca-005116	Anolis carolinensis	84.17	0.00e+00	854.00
IUUC-Ame-011220	Astyanax mexicanus	73.24	0.00e+00	753.00
IUUC-Bta-013368	Bos taurus	92.64	0.00e+00	906.00
IUUC-Cel-018461	Caenorhabditis elegans	33.16	1.00e-51	197.00
IUUC-Cja-019133	Callithrix jacchus	98.26	0.00e+00	952.00
IUUC-Cfa-020800	Canis familiaris	95.17	0.00e+00	930.00
IUUC-Cpo-021685	Cavia porcellus	92.13	0.00e+00	920.00
IUUC-Csa-023325	Chlorocebus sabaeus	99.61	0.00e+00	970.00
IUUC-Cho-024556	Choloepus hoffmanni	88.74	0.00e+00	806.00
IUUC-Cin-025766	Ciona intestinalis	38.72	2.00e-51	196.00
IUUC-Csv-026035	Ciona savignyi	39.78	5.00e-47	181.00
IUUC-Cgl-026648	Colletotrichum gloeosporioides	27.21	5.00e-40	159.00
IUUC-Dre-028379	Danio rerio	73.03	0.00e+00	755.00
IUUC-Dno-029288	Dasypus novemcinctus	87.78	0.00e+00	875.00
IUUC-Dor-030515	Dipodomys ordii	86.29	0.00e+00	783.00
IUUC-Dme-031987	Drosophila melanogaster	45.41	1.00e-98	353.00
IUUC-Ete-032804	Echinops telfairi	77.13	0.00e+00	679.00
IUUC-Eca-033520	Equus caballus	92.53	0.00e+00	870.00
IUUC-Eeu-034820	Erinaceus europaeus	92.05	0.00e+00	842.00
IUUC-Fca-035914	Felis catus	95.53	0.00e+00	932.00
IUUC-Fal-037355	Ficedula albicollis	88.74	0.00e+00	828.00
IUUC-Fox-037748	Fusarium oxysporum	31.27	9.00e-40	158.00
IUUC-Fso-038126	Fusarium solani	27.86	4.00e-41	162.00
IUUC-Gmo-039628	Gadus morhua	82.47	0.00e+00	677.00
IUUC-Gga-041110	Gallus gallus	87.07	0.00e+00	904.00
IUUC-Gac-042301	Gasterosteus aculeatus	84.58	0.00e+00	739.00
IUUC-Ggo-044963	Gorilla gorilla	99.23	0.00e+00	966.00
IUUC-Hsa-046159	Homo sapiens	99.03	0.00e+00	966.00
IUUC-Itr-048016	Ictidomys tridecemlineatus	92.53	0.00e+00	636.00
IUUC-Kpa-049200	Komagataella pastoris	24.52	9.00e-26	111.00
IUUC-Lch-050447	Latimeria chalumnae	79.07	0.00e+00	807.00
IUUC-Loc-052761	Lepisosteus oculatus	77.26	0.00e+00	759.00
IUUC-Laf-053662	Loxodonta africana	90.98	0.00e+00	902.00
IUUC-Meu-056371	Macropus eugenii	74.01	0.00e+00	702.00
IUUC-Mga-060117	Meleagris gallopavo	84.69	0.00e+00	875.00
IUUC-Mmr-061413	Microcebus murinus	94.40	0.00e+00	912.00
IUUC-Mdo-061951	Monodelphis domestica	92.11	0.00e+00	926.00
IUUC-Mmu-063771	Mus musculus	89.73	0.00e+00	942.00
IUUC-Mpu-066335	Mustela putorius furo	89.80	0.00e+00	836.00
IUUC-Mlu-067740	Myotis lucifugus	92.89	0.00e+00	882.00
IUUC-Nle-069083	Nomascus leucogenys	98.84	0.00e+00	965.00
IUUC-Opr-071162	Ochotona princeps	77.54	5.00e-147	514.00
IUUC-Ont-072360	Oreochromis niloticus	74.70	0.00e+00	756.00
IUUC-Oan-073093	Ornithorhynchus anatinus	85.35	0.00e+00	824.00
IUUC-Ocu-074641	Oryctolagus cuniculus	94.48	0.00e+00	899.00
IUUC-Ola-087487	Oryzias latipes	78.49	0.00e+00	711.00
IUUC-Oga-088551	Otolemur garnettii	94.98	0.00e+00	970.00
IUUC-Oar-089972	Ovis aries	92.64	0.00e+00	905.00
IUUC-Ptr-090672	Pan troglodytes	99.23	0.00e+00	966.00
IUUC-Pan-092407	Papio anubis	99.79	0.00e+00	926.00
IUUC-Psi-092953	Pelodiscus sinensis	85.14	0.00e+00	862.00
IUUC-Pma-094312	Petromyzon marinus	70.87	6.00e-160	556.00
IUUC-Pno-094911	Phaeosphaeria nodorum	33.33	7.00e-36	144.00
IUUC-Pfo-096030	Poecilia formosa	82.34	0.00e+00	729.00
IUUC-Pab-097691	Pongo abelii	99.42	0.00e+00	967.00
IUUC-Pca-100396	Procavia capensis	82.31	0.00e+00	654.00
IUUC-Pva-103120	Pteropus vampyrus	94.79	0.00e+00	915.00
IUUC-Pgr-103679	Puccinia graminis	39.84	3.00e-20	94.00
IUUC-Ptt-103709	Puccinia triticina	39.84	1.00e-20	95.10
IUUC-Pte-104251	Pyrenophora teres	29.27	5.00e-39	155.00
IUUC-Pyt-104694	Pyrenophora triticirepentis	29.63	1.00e-39	157.00
IUUC-Rno-105982	Rattus norvegicus	89.14	0.00e+00	919.00
IUUC-Sha-106927	Sarcophilus harrisii	89.96	0.00e+00	946.00
IUUC-Sar-113551	Sorex araneus	95.46	0.00e+00	877.00
IUUC-Ssc-115322	Sus scrofa	96.87	0.00e+00	806.00
IUUC-Tgu-116550	Taeniopygia guttata	86.49	0.00e+00	892.00
IUUC-Tru-118646	Takifugu rubripes	82.65	0.00e+00	719.00
IUUC-Tsy-118874	Tarsius syrichta	95.37	0.00e+00	925.00
IUUC-Tni-120235	Tetraodon nigroviridis	72.46	0.00e+00	720.00
IUUC-Tme-127104	Tuber melanosporum	27.54	7.00e-36	145.00
IUUC-Tbe-127233	Tupaia belangeri	90.15	2.00e-163	569.00
IUUC-Ttr-129298	Tursiops truncatus	86.24	0.00e+00	832.00
IUUC-Vpa-130071	Vicugna pacos	87.45	0.00e+00	815.00
IUUC-Xtr-131863	Xenopus tropicalis	80.44	0.00e+00	788.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence