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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Rno-105746
Ensembl Protein ID ENSRNOP00000073697.1
UniProt Accession Q9Z1Z3; EPN2_RAT
Genbank Protein ID AAC79495.1
Protein Name Epsin-2; EPS-15-interacting protein 2
Genbank Nucleotide ID AF096269
Gene Name Epn2
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000060550.1 ENSRNOT00000087102.1 ENSRNOP00000070453.1
ENSRNOG00000060550.1 ENSRNOT00000085703.1 ENSRNOP00000074461.1
ENSRNOG00000060550.1 ENSRNOT00000091963.1 ENSRNOP00000073697.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
iRefIndex
Post-translational Modifications (PTMs)
dbPAFPhosphositePlusUniProt
Protein Expression/Proteomics
GPMDB
Status Reviewed
Details
Family Domain References (PMIDs)
UBD/Alpha-Helix/UIM UIM 11919637
Classification
Family E-value Score Start End
UBD/Alpha-Helix/UIM 0.00047 20.4 218 236
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   UBD/Alpha-Helix/UIM
   S: 1    dEdeeLqlAlalSlqEeee 19
           +E+++LqlAla+S++++e+
   Q: 218  EEELQLQLALAMSREVAEQ 236
           79***************98 PP
   
Organism Rattus norvegicus
Functional Description
(View)

Functional Description


     Plays a role in the formation of clathrin-coated invaginations and endocytosis.
 Plays a role in the formation of clathrin-coated invaginations and endocytosis.
Protein Sequence
(Fasta)
MTTSSIRRQM KNIVNNYSEA EIKVREATSN DPWGPSSSLM TEIADLTYNV VAFSEIMSMV 60
WKRLNDHGKN WRHVYKALTL LDYLIKTGSE RVAQQCRENI FAIQTLKDFQ YIDRDGKDQG 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105746|UBD,UIM|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GTGTGGGTGT CAAACGCTGC ACGGGCTCGG GTCGCTCCCG CCTCTCCAGC GTCGCCGGCG 60
GCTGCAGCCT TGCACTCGCG CTGGCCGGGA ACAGAGGTGA GCCGGGACTC GCGGGGCTTG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105746|UBD,UIM|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0254--Endocytosis
KW-0446--Lipid-binding
KW-0488--Methylation
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation
Interpro

IPR013809--ENTH
IPR008942--ENTH_VHS
IPR027319--Epsin-2_metazoa
IPR003903--UIM_dom
PROSITE

PS50942--ENTH
PS50330--UIM
Pfam

PF01417--ENTH
SMART

SM00273--ENTH
SM00726--UIM
Gene Ontology

GO:0030128--C:clathrin coat of endocytic vesicle
GO:0008289--F:lipid binding
GO:0006897--P:endocytosis
GO:0030100--P:regulation of endocytosis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000113 Aegilops tauschii 49.32 2.00e-41 164.00
IUUC-Aml-001209 Ailuropoda melanoleuca 85.23 0.00e+00 850.00
IUUC-Apl-003474 Anas platyrhynchos 62.84 0.00e+00 657.00
IUUC-Aca-005348 Anolis carolinensis 70.25 0.00e+00 680.00
IUUC-Aly-006457 Arabidopsis lyrata 47.17 1.00e-41 164.00
IUUC-Ath-007675 Arabidopsis thaliana 47.17 8.00e-42 165.00
IUUC-Ago-007986 Ashbya gossypii 46.75 4.00e-39 155.00
IUUC-Ate-010292 Aspergillus terreus 53.79 3.00e-39 156.00
IUUC-Ame-011423 Astyanax mexicanus 61.91 4.00e-140 491.00
IUUC-Bta-013258 Bos taurus 73.64 0.00e+00 712.00
IUUC-Bdi-014129 Brachypodium distachyon 48.37 3.00e-42 167.00
IUUC-Bol-016058 Brassica oleracea 47.17 6.00e-42 166.00
IUUC-Bra-017893 Brassica rapa 47.17 1.00e-41 165.00
IUUC-Cel-018350 Caenorhabditis elegans 45.11 1.00e-81 296.00
IUUC-Cja-019818 Callithrix jacchus 83.90 0.00e+00 833.00
IUUC-Cfa-020229 Canis familiaris 82.68 0.00e+00 813.00
IUUC-Cpo-022174 Cavia porcellus 86.10 0.00e+00 812.00
IUUC-Csa-023789 Chlorocebus sabaeus 86.78 0.00e+00 862.00
IUUC-Cho-024649 Choloepus hoffmanni 61.29 3.00e-56 213.00
IUUC-Cin-025755 Ciona intestinalis 69.16 4.00e-85 306.00
IUUC-Csv-025907 Ciona savignyi 43.43 2.00e-96 346.00
IUUC-Cgl-026614 Colletotrichum gloeosporioides 55.26 2.00e-46 180.00
IUUC-Cne-027047 Cryptococcus neoformans 57.81 1.00e-41 164.00
IUUC-Cme-027132 Cyanidioschyzon merolae 34.97 1.00e-24 107.00
IUUC-Dre-028037 Danio rerio 60.77 8.00e-143 500.00
IUUC-Dno-029660 Dasypus novemcinctus 71.84 1.00e-179 623.00
IUUC-Dor-030230 Dipodomys ordii 89.64 8.00e-116 410.00
IUUC-Dme-032149 Drosophila melanogaster 52.15 1.00e-89 324.00
IUUC-Ete-032944 Echinops telfairi 91.03 1.00e-116 414.00
IUUC-Eca-033636 Equus caballus 67.24 0.00e+00 706.00
IUUC-Eeu-034601 Erinaceus europaeus 74.17 3.00e-98 352.00
IUUC-Fca-036004 Felis catus 75.62 0.00e+00 722.00
IUUC-Fal-036640 Ficedula albicollis 73.27 0.00e+00 740.00
IUUC-Fox-037900 Fusarium oxysporum 39.71 2.00e-33 137.00
IUUC-Gmo-038468 Gadus morhua 61.98 5.00e-132 464.00
IUUC-Gga-040781 Gallus gallus 73.40 0.00e+00 768.00
IUUC-Gac-042432 Gasterosteus aculeatus 60.57 1.00e-142 499.00
IUUC-Gma-042967 Glycine max 49.06 2.00e-43 171.00
IUUC-Ggo-044421 Gorilla gorilla 80.36 8.00e-126 444.00
IUUC-Hsa-045740 Homo sapiens 80.36 3.00e-126 445.00
IUUC-Hvu-047135 Hordeum vulgare 48.37 6.00e-42 166.00
IUUC-Itr-048090 Ictidomys tridecemlineatus 83.29 2.00e-144 505.00
IUUC-Lch-049618 Latimeria chalumnae 68.20 0.00e+00 683.00
IUUC-Lpe-051296 Leersia perrieri 49.02 2.00e-43 171.00
IUUC-Loc-051728 Lepisosteus oculatus 66.73 1.00e-163 569.00
IUUC-Laf-053389 Loxodonta africana 77.53 0.00e+00 731.00
IUUC-Mcc-055565 Macaca mulatta 97.99 4.00e-116 412.00
IUUC-Mga-060111 Meleagris gallopavo 73.96 0.00e+00 772.00
IUUC-Mvi-060293 Microbotryum violaceum 54.19 6.00e-48 185.00
IUUC-Mmr-060793 Microcebus murinus 90.87 9.00e-117 414.00
IUUC-Mdo-061941 Monodelphis domestica 71.43 0.00e+00 711.00
IUUC-Mmu-064004 Mus musculus 93.51 4.00e-157 548.00
IUUC-Mpu-066625 Mustela putorius furo 89.95 1.00e-115 410.00
IUUC-Mlu-068085 Myotis lucifugus 70.59 0.00e+00 677.00
IUUC-Ncr-068627 Neurospora crassa 37.83 1.00e-38 154.00
IUUC-Nle-069825 Nomascus leucogenys 79.85 3.00e-125 442.00
IUUC-Opr-070492 Ochotona princeps 77.75 1.00e-92 333.00
IUUC-Ont-072355 Oreochromis niloticus 57.24 2.00e-138 486.00
IUUC-Oan-073743 Ornithorhynchus anatinus 76.55 0.00e+00 773.00
IUUC-Ocu-074139 Oryctolagus cuniculus 80.16 0.00e+00 683.00
IUUC-Oba-075922 Oryza barthii 49.02 2.00e-43 171.00
IUUC-Obr-076552 Oryza brachyantha 48.37 9.00e-43 169.00
IUUC-Ogl-077885 Oryza glaberrima 49.02 2.00e-43 171.00
IUUC-Ogu-078795 Oryza glumaepatula 49.02 1.00e-43 171.00
IUUC-Oin-080196 Oryza indica 49.02 2.00e-43 171.00
IUUC-Olo-080509 Oryza longistaminata 49.02 1.00e-43 171.00
IUUC-Ome-081531 Oryza meridionalis 49.02 1.00e-43 171.00
IUUC-Oni-083003 Oryza nivara 49.02 2.00e-43 171.00
IUUC-Opu-083829 Oryza punctata 49.02 2.00e-43 171.00
IUUC-Oru-084248 Oryza rufipogon 49.02 2.00e-43 171.00
IUUC-Osa-085910 Oryza sativa 49.02 2.00e-43 171.00
IUUC-Ola-087087 Oryzias latipes 86.15 8.00e-93 334.00
IUUC-Olu-087896 Ostreococcus lucimarinus 35.21 7.00e-18 83.60
IUUC-Oga-088870 Otolemur garnettii 85.59 0.00e+00 866.00
IUUC-Oar-090233 Ovis aries 88.39 7.00e-117 414.00
IUUC-Ptr-091026 Pan troglodytes 80.36 9.00e-126 444.00
IUUC-Pan-092050 Papio anubis 86.78 0.00e+00 832.00
IUUC-Psi-093688 Pelodiscus sinensis 72.46 0.00e+00 774.00
IUUC-Pma-094335 Petromyzon marinus 60.54 7.00e-146 510.00
IUUC-Pfo-096650 Poecilia formosa 53.48 5.00e-116 411.00
IUUC-Pab-098209 Pongo abelii 80.61 2.00e-135 476.00
IUUC-Pop-098881 Populus trichocarpa 49.02 1.00e-42 168.00
IUUC-Pca-100479 Procavia capensis 70.28 0.00e+00 724.00
IUUC-Ppe-101157 Prunus persica 49.02 7.00e-42 166.00
IUUC-Pva-102177 Pteropus vampyrus 75.51 1.00e-110 393.00
IUUC-Ptt-103708 Puccinia triticina 53.95 5.00e-41 161.00
IUUC-Sce-106344 Saccharomyces cerevisiae 52.67 8.00e-37 147.00
IUUC-Sha-107254 Sarcophilus harrisii 72.26 0.00e+00 760.00
IUUC-Sit-109784 Setaria italica 49.02 8.00e-43 169.00
IUUC-Sly-111438 Solanum lycopersicum 47.80 5.00e-43 169.00
IUUC-Stu-112874 Solanum tuberosum 47.80 4.00e-43 170.00
IUUC-Sar-113696 Sorex araneus 97.49 4.00e-116 412.00
IUUC-Sbi-114540 Sorghum bicolor 47.71 4.00e-42 167.00
IUUC-Sre-114959 Sporisorium reilianum 55.97 8.00e-43 167.00
IUUC-Tgu-117391 Taeniopygia guttata 80.45 0.00e+00 746.00
IUUC-Tru-117791 Takifugu rubripes 46.59 6.00e-94 338.00
IUUC-Tsy-119034 Tarsius syrichta 62.82 4.00e-60 226.00
IUUC-Tni-120827 Tetraodon nigroviridis 60.49 7.00e-149 520.00
IUUC-Tca-121377 Theobroma cacao 48.10 1.00e-42 168.00
IUUC-Tae-122690 Triticum aestivum 48.37 4.00e-42 166.00
IUUC-Tur-126042 Triticum urartu 48.37 4.00e-42 166.00
IUUC-Tbe-127405 Tupaia belangeri 89.50 3.00e-115 408.00
IUUC-Ttr-128595 Tursiops truncatus 67.82 8.00e-128 451.00
IUUC-Uma-129605 Ustilago maydis 58.40 9.00e-43 167.00
IUUC-Vpa-130825 Vicugna pacos 61.68 1.00e-60 227.00
IUUC-Vvi-131209 Vitis vinifera 47.83 3.00e-41 162.00
IUUC-Xtr-132334 Xenopus tropicalis 66.83 0.00e+00 640.00
IUUC-Xma-134173 Xiphophorus maculatus 53.06 9.00e-128 450.00
IUUC-Yli-134375 Yarrowia lipolytica 50.00 3.00e-39 156.00
Created Date 25-Jun-2017

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