iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Lch-049689

Ensembl Protein ID

ENSLACP00000003541.1

UniProt Accession

H3A1M0; H3A1M0_LATCH

Genbank Protein ID

ENSLACP00000003541

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AFYH01224014

Gene Name

SCAP

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSLACG00000003155.1	ENSLACT00000003572.1	ENSLACP00000003541.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.10e-16	59.6	1121	1154

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH++++t++   d t+ l+sG+ Dg i +WD+ tg
   Q: 1121 GHSGGITAVYI-DqTMvLASGGQDGAICLWDVLTG 1154
           8********88.446648*************9887 PP

Organism

Latimeria chalumnae

Protein Sequence
(Fasta)

MTLTEKLREK ISRAFYNHGL LCASYPIPII LFTALCILAC CYPLLKLPLP GTGPVEYTTP 60
VRDYSPPPSY LSHGQEDKTE GPDWYVGSPV AYVQQIFVKA IVAPWNKNLL PVDVFRSPLS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGACCCTAA CTGAAAAGCT GCGGGAGAAG ATATCGCGGG CATTTTACAA CCACGGGCTC 60
CTGTGTGCGT CCTACCCAAT TCCCATCATC CTCTTCACCG CTCTCTGTAT TTTGGCCTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0019915--P:lipid storage
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	75.46	0.00e+00	867.00
IUUC-Apl-003294	Anas platyrhynchos	75.00	0.00e+00	1753.00
IUUC-Aca-004424	Anolis carolinensis	67.15	0.00e+00	1509.00
IUUC-Bta-013478	Bos taurus	69.93	0.00e+00	1595.00
IUUC-Cel-018160	Caenorhabditis elegans	25.00	3.00e-65	243.00
IUUC-Cja-019123	Callithrix jacchus	69.75	0.00e+00	1592.00
IUUC-Cfa-021082	Canis familiaris	70.06	0.00e+00	1560.00
IUUC-Cpo-022477	Cavia porcellus	68.43	0.00e+00	1522.00
IUUC-Csa-023176	Chlorocebus sabaeus	68.88	0.00e+00	1566.00
IUUC-Cin-025490	Ciona intestinalis	37.79	1.00e-91	330.00
IUUC-Csv-026115	Ciona savignyi	36.94	9.00e-130	458.00
IUUC-Dre-028008	Danio rerio	65.98	0.00e+00	1536.00
IUUC-Dno-028887	Dasypus novemcinctus	72.53	0.00e+00	956.00
IUUC-Dor-030467	Dipodomys ordii	78.89	0.00e+00	737.00
IUUC-Dme-032087	Drosophila melanogaster	32.26	8.00e-111	395.00
IUUC-Ete-032372	Echinops telfairi	58.94	0.00e+00	920.00
IUUC-Eca-033896	Equus caballus	70.39	0.00e+00	1666.00
IUUC-Eeu-035099	Erinaceus europaeus	67.68	0.00e+00	965.00
IUUC-Fca-035616	Felis catus	74.92	0.00e+00	875.00
IUUC-Fal-037231	Ficedula albicollis	72.02	0.00e+00	1650.00
IUUC-Gmo-039439	Gadus morhua	70.88	0.00e+00	648.00
IUUC-Gac-041516	Gasterosteus aculeatus	63.98	0.00e+00	1493.00
IUUC-Hsa-046674	Homo sapiens	70.37	0.00e+00	1625.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	70.39	0.00e+00	1615.00
IUUC-Loc-052417	Lepisosteus oculatus	54.08	1.00e-154	539.00
IUUC-Laf-053795	Loxodonta africana	70.20	0.00e+00	1632.00
IUUC-Mcc-055502	Macaca mulatta	70.11	0.00e+00	1625.00
IUUC-Mga-059805	Meleagris gallopavo	75.39	0.00e+00	1743.00
IUUC-Mmr-060997	Microcebus murinus	70.39	0.00e+00	1647.00
IUUC-Mdo-062940	Monodelphis domestica	73.01	0.00e+00	1653.00
IUUC-Mmu-063255	Mus musculus	70.69	0.00e+00	1623.00
IUUC-Mpu-066158	Mustela putorius furo	70.40	0.00e+00	1623.00
IUUC-Mlu-067201	Myotis lucifugus	67.61	0.00e+00	1552.00
IUUC-Nle-069145	Nomascus leucogenys	72.74	0.00e+00	1036.00
IUUC-Opr-070797	Ochotona princeps	66.31	0.00e+00	1480.00
IUUC-Ont-071553	Oreochromis niloticus	65.05	0.00e+00	1521.00
IUUC-Ocu-074598	Oryctolagus cuniculus	70.06	0.00e+00	1586.00
IUUC-Ola-086650	Oryzias latipes	83.78	7.00e-113	399.00
IUUC-Oar-089287	Ovis aries	67.26	0.00e+00	854.00
IUUC-Pan-092004	Papio anubis	70.12	0.00e+00	1598.00
IUUC-Psi-093028	Pelodiscus sinensis	70.88	0.00e+00	1539.00
IUUC-Pma-094145	Petromyzon marinus	48.42	0.00e+00	1104.00
IUUC-Pfo-096320	Poecilia formosa	65.40	0.00e+00	1529.00
IUUC-Pab-097862	Pongo abelii	70.68	0.00e+00	1630.00
IUUC-Pca-100862	Procavia capensis	60.49	0.00e+00	1265.00
IUUC-Pva-103050	Pteropus vampyrus	72.05	0.00e+00	1013.00
IUUC-Rno-105852	Rattus norvegicus	70.81	0.00e+00	1620.00
IUUC-Sha-107312	Sarcophilus harrisii	72.43	0.00e+00	1674.00
IUUC-Sar-113311	Sorex araneus	65.23	0.00e+00	634.00
IUUC-Ssc-116356	Sus scrofa	70.06	0.00e+00	1644.00
IUUC-Tgu-116896	Taeniopygia guttata	57.33	4.00e-170	592.00
IUUC-Tru-118197	Takifugu rubripes	65.16	0.00e+00	1508.00
IUUC-Tni-119823	Tetraodon nigroviridis	62.29	0.00e+00	1479.00
IUUC-Ttr-129164	Tursiops truncatus	70.49	0.00e+00	1609.00
IUUC-Xtr-132819	Xenopus tropicalis	69.75	0.00e+00	1702.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence