iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tni-119823

UUCD1 version

UUC-TeN-00560

Ensembl Protein ID

ENSTNIP00000006749.1

UniProt Accession

H3CES5; H3CES5_TETNG

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTNIG00000004132.1	ENSTNIT00000006900.1	ENSTNIP00000006749.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	4.20e-17	61.8	1059	1092

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tl.lvsGsdDgtikvWDlrtg 33
           gH+++vt++ + d t+ l+sG+ Dg i +WD+ tg
   Q: 1059 GHAGGVTAVYL-DqTMvLASGGQDGAICLWDVLTG 1092
           8********88.446648*************9887 PP

Organism

Tetraodon nigroviridis

Protein Sequence
(Fasta)

PRMTLRQQLR EKISAAFYRH GLLCASYPVP IILFTSASIL TCCYPLLRLP CRDYGVPGVE 60
PVGYLGERPD WYRGPPVAYI QQVLVKAAVS PWDSSLVPVD VFRSPLGRAF SLLEEIRDHV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCAGGATGA CGCTGCGCCA GCAGCTGCGA GAGAAGATCT CGGCGGCGTT CTACCGCCAC 60
GGGCTGCTGT GTGCCTCCTA CCCGGTGCCC ATCATCCTCT TCACCTCCGC CAGCATCCTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0677--Repeat
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0853--WD repeat

Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR030225--SCAP
IPR000731--SSD
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS50156--SSD
PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12349--Sterol-sensing
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005789--C:endoplasmic reticulum membrane
GO:0000139--C:Golgi membrane
GO:0016021--C:integral component of membrane
GO:0015485--F:cholesterol binding
GO:0008203--P:cholesterol metabolic process
GO:0019915--P:lipid storage
GO:0032933--P:SREBP signaling pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001802	Ailuropoda melanoleuca	69.83	0.00e+00	796.00
IUUC-Apl-003294	Anas platyrhynchos	65.44	0.00e+00	1480.00
IUUC-Aca-004424	Anolis carolinensis	61.55	0.00e+00	1324.00
IUUC-Bta-013478	Bos taurus	65.41	0.00e+00	1448.00
IUUC-Cel-018160	Caenorhabditis elegans	26.63	1.00e-66	248.00
IUUC-Cja-019123	Callithrix jacchus	63.25	0.00e+00	1378.00
IUUC-Cfa-021082	Canis familiaris	65.33	0.00e+00	1415.00
IUUC-Cpo-022477	Cavia porcellus	63.82	0.00e+00	1378.00
IUUC-Csa-023176	Chlorocebus sabaeus	65.19	0.00e+00	1418.00
IUUC-Cin-025490	Ciona intestinalis	39.02	2.00e-89	324.00
IUUC-Csv-026115	Ciona savignyi	36.07	4.00e-123	436.00
IUUC-Dre-028008	Danio rerio	78.03	0.00e+00	1755.00
IUUC-Dno-028887	Dasypus novemcinctus	69.14	0.00e+00	853.00
IUUC-Dor-030467	Dipodomys ordii	71.43	0.00e+00	657.00
IUUC-Dme-032087	Drosophila melanogaster	31.42	2.00e-103	370.00
IUUC-Ete-032372	Echinops telfairi	58.32	0.00e+00	749.00
IUUC-Eca-033896	Equus caballus	65.42	0.00e+00	1490.00
IUUC-Eeu-035099	Erinaceus europaeus	61.91	0.00e+00	820.00
IUUC-Fca-035616	Felis catus	67.30	0.00e+00	801.00
IUUC-Fal-037231	Ficedula albicollis	64.87	0.00e+00	1430.00
IUUC-Gmo-039439	Gadus morhua	72.81	0.00e+00	988.00
IUUC-Gac-041516	Gasterosteus aculeatus	80.88	0.00e+00	1844.00
IUUC-Hsa-046674	Homo sapiens	65.16	0.00e+00	1446.00
IUUC-Itr-048879	Ictidomys tridecemlineatus	64.39	0.00e+00	1451.00
IUUC-Lch-049689	Latimeria chalumnae	62.69	0.00e+00	1431.00
IUUC-Loc-052417	Lepisosteus oculatus	65.58	2.00e-176	612.00
IUUC-Laf-053795	Loxodonta africana	64.22	0.00e+00	1432.00
IUUC-Mcc-055502	Macaca mulatta	65.26	0.00e+00	1464.00
IUUC-Mga-059805	Meleagris gallopavo	65.26	0.00e+00	1483.00
IUUC-Mmr-060997	Microcebus murinus	64.32	0.00e+00	1473.00
IUUC-Mdo-062940	Monodelphis domestica	64.14	0.00e+00	1404.00
IUUC-Mmu-063255	Mus musculus	65.74	0.00e+00	1431.00
IUUC-Mpu-066158	Mustela putorius furo	66.03	0.00e+00	1456.00
IUUC-Mlu-067201	Myotis lucifugus	64.09	0.00e+00	1412.00
IUUC-Nle-069145	Nomascus leucogenys	65.25	0.00e+00	924.00
IUUC-Opr-070797	Ochotona princeps	61.08	0.00e+00	1308.00
IUUC-Ont-071553	Oreochromis niloticus	80.77	0.00e+00	1820.00
IUUC-Ocu-074598	Oryctolagus cuniculus	65.77	0.00e+00	1452.00
IUUC-Ola-086650	Oryzias latipes	93.69	1.00e-122	431.00
IUUC-Oar-089287	Ovis aries	65.92	0.00e+00	781.00
IUUC-Pan-092004	Papio anubis	65.37	0.00e+00	1438.00
IUUC-Psi-093028	Pelodiscus sinensis	60.69	0.00e+00	1264.00
IUUC-Pma-094145	Petromyzon marinus	48.12	0.00e+00	1063.00
IUUC-Pfo-096320	Poecilia formosa	81.75	0.00e+00	1853.00
IUUC-Pab-097862	Pongo abelii	65.56	0.00e+00	1454.00
IUUC-Pca-100862	Procavia capensis	56.13	0.00e+00	1116.00
IUUC-Pva-103050	Pteropus vampyrus	68.05	0.00e+00	914.00
IUUC-Rno-105852	Rattus norvegicus	66.05	0.00e+00	1442.00
IUUC-Sha-107312	Sarcophilus harrisii	64.29	0.00e+00	1415.00
IUUC-Sar-113311	Sorex araneus	60.85	2.00e-164	573.00
IUUC-Ssc-116356	Sus scrofa	65.08	0.00e+00	1481.00
IUUC-Tgu-116896	Taeniopygia guttata	54.10	2.00e-130	459.00
IUUC-Tru-118197	Takifugu rubripes	85.76	0.00e+00	1936.00
IUUC-Ttr-129164	Tursiops truncatus	65.21	0.00e+00	1463.00
IUUC-Xtr-132819	Xenopus tropicalis	62.13	0.00e+00	1467.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence