iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.20e-24	84.5	391	422
UBD/Beta-Prp	4.80e-54	183.6	307	499

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH++++tc+a+ sd  ++++G+ D ++k+W++
   Q: 391  GHSSEMTCIAYsSDgQFIATGGEDSKVKLWNT 422
           8***********999***************96 PP

UBD/Beta-Prp

   S: 9    hksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseD.rtikvwdlstgkcvhtlkghedsvlslsfsps 105
           ++ ++t+  +   +++l++++ +g   ++++ + ++++sls  + +++a  f+ +g++ + +s+  + + vw+ ++ +++++ +gh+++ +++++s +
   Q: 307  RDVQLTAANYNTRTKVLVVAFSSGAFYLYELPDVNMIHSLSISDYPISAALFNCTGDWVALASREiGQLLVWEWQSEQYIMKQQGHSSEMTCIAYSSD 404
           45556666666667777777777777777777777777777777777777777777777777777777777777777777777777777777777777 PP
   S: 106  gdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           g+++++G++d+ +++w++++  c+  t+s+h++ v++++++ +++ lvs+slD+tvr +d+++ +  rt+t+ +  +  ++++d++g+ +v+g++d
   Q: 405  GQFIATGGEDSKVKLWNTQSSFCFV-TFSEHTSGVTGIQFSRNKKFLVSSSLDGTVRAFDVNRYRNFRTFTSPNPAQFSCVAVDYSGELVVAGGQD 499
           7777777777777777777777777.7777777777777777777777777777777777777777777777777777777777777777777665 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MKFSYKFSNL LGTIYRNGNL VFTPDGNSVI SPVGNRITVY DLKNNKSRTL SLESRYNYTN 60
IALSPDGSLL IAVNEKGEAQ LISMMSCTVI HRHKFQTGVQ CICFSPNGAF FAVAVQNVVL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AACTGGTATG ACAGTTACCG TAAATGTGAA GTGATTATTT TATAACATGA ATTCAAAAAA 60
TTAAAGTTTA AGCAATGAAG TATTTTAAAA ATTAAGTATT ATGTTATATA TTCTTATAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR023302--Pept_S9A_N
IPR027145--PWP2
IPR011044--Quino_amine_DH_bsu
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0009267--P:cellular response to starvation
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0022008--P:neurogenesis
GO:0000028--P:ribosomal small subunit assembly

KEGG

dme:Dmel_CG12325

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001932	Ailuropoda melanoleuca	45.91	0.00e+00	830.00
IUUC-Atr-003033	Amborella trichopoda	35.60	1.00e-156	546.00
IUUC-Apl-003219	Anas platyrhynchos	47.88	0.00e+00	841.00
IUUC-Aca-004950	Anolis carolinensis	47.45	0.00e+00	856.00
IUUC-Aly-006213	Arabidopsis lyrata	36.85	2.00e-160	558.00
IUUC-Ath-006593	Arabidopsis thaliana	37.00	1.00e-158	553.00
IUUC-Ago-007916	Ashbya gossypii	41.81	2.00e-133	469.00
IUUC-Acl-008225	Aspergillus clavatus	40.21	0.00e+00	674.00
IUUC-Afl-008390	Aspergillus flavus	40.41	0.00e+00	657.00
IUUC-Afu-009039	Aspergillus fumigatus	39.70	0.00e+00	663.00
IUUC-Ani-009228	Aspergillus nidulans	37.77	7.00e-162	563.00
IUUC-Ang-009663	Aspergillus niger	39.33	1.00e-180	625.00
IUUC-Aor-009923	Aspergillus oryzae	40.41	0.00e+00	657.00
IUUC-Ate-010264	Aspergillus terreus	40.63	0.00e+00	664.00
IUUC-Ame-010790	Astyanax mexicanus	44.06	5.00e-101	360.00
IUUC-Bgr-012066	Blumeria graminis	39.34	0.00e+00	643.00
IUUC-Bta-012399	Bos taurus	47.71	0.00e+00	811.00
IUUC-Bci-013757	Botrytis cinerea	43.43	4.00e-137	481.00
IUUC-Bdi-015028	Brachypodium distachyon	38.82	3.00e-167	581.00
IUUC-Bol-016521	Brassica oleracea	36.87	2.00e-162	565.00
IUUC-Bra-017096	Brassica rapa	37.32	2.00e-162	565.00
IUUC-Cel-018690	Caenorhabditis elegans	35.95	2.00e-169	589.00
IUUC-Cja-019229	Callithrix jacchus	46.34	0.00e+00	836.00
IUUC-Cfa-020504	Canis familiaris	46.68	0.00e+00	841.00
IUUC-Cpo-021574	Cavia porcellus	46.83	0.00e+00	833.00
IUUC-Cre-022756	Chlamydomonas reinhardtii	41.58	4.00e-126	445.00
IUUC-Csa-023436	Chlorocebus sabaeus	47.10	0.00e+00	822.00
IUUC-Cin-025397	Ciona intestinalis	47.97	0.00e+00	717.00
IUUC-Csv-026194	Ciona savignyi	47.80	1.00e-145	509.00
IUUC-Cgl-026684	Colletotrichum gloeosporioides	37.89	8.00e-175	606.00
IUUC-Cne-027031	Cryptococcus neoformans	39.59	0.00e+00	707.00
IUUC-Cme-027276	Cyanidioschyzon merolae	32.47	2.00e-114	406.00
IUUC-Dre-027514	Danio rerio	46.05	0.00e+00	804.00
IUUC-Dno-029191	Dasypus novemcinctus	45.15	0.00e+00	699.00
IUUC-Dor-030149	Dipodomys ordii	47.10	0.00e+00	824.00
IUUC-Dse-031260	Dothistroma septosporum	44.44	8.00e-132	463.00
IUUC-Ete-033102	Echinops telfairi	50.73	2.00e-165	575.00
IUUC-Eca-033223	Equus caballus	46.64	0.00e+00	828.00
IUUC-Fca-035795	Felis catus	44.78	0.00e+00	762.00
IUUC-Fal-036830	Ficedula albicollis	47.61	0.00e+00	824.00
IUUC-Fox-037835	Fusarium oxysporum	38.03	3.00e-171	595.00
IUUC-Fso-038324	Fusarium solani	38.59	6.00e-167	580.00
IUUC-Gmo-039355	Gadus morhua	45.33	0.00e+00	791.00
IUUC-Ggr-039840	Gaeumannomyces graminis	39.31	6.00e-172	597.00
IUUC-Gga-040907	Gallus gallus	51.90	8.00e-161	559.00
IUUC-Gac-042624	Gasterosteus aculeatus	45.27	0.00e+00	784.00
IUUC-Gma-043034	Glycine max	37.61	6.00e-169	587.00
IUUC-Hsa-046145	Homo sapiens	46.13	0.00e+00	840.00
IUUC-Hvu-047416	Hordeum vulgare	38.10	9.00e-169	586.00
IUUC-Itr-049083	Ictidomys tridecemlineatus	46.63	0.00e+00	840.00
IUUC-Kpa-049150	Komagataella pastoris	36.99	4.00e-170	590.00
IUUC-Lch-049460	Latimeria chalumnae	45.86	0.00e+00	722.00
IUUC-Lpe-050840	Leersia perrieri	38.48	7.00e-165	573.00
IUUC-Loc-052733	Lepisosteus oculatus	44.74	0.00e+00	809.00
IUUC-Lma-053277	Leptosphaeria maculans	37.07	4.00e-161	561.00
IUUC-Laf-054294	Loxodonta africana	48.95	0.00e+00	815.00
IUUC-Mcc-054624	Macaca mulatta	47.61	0.00e+00	843.00
IUUC-Meu-056665	Macropus eugenii	42.54	3.00e-161	561.00
IUUC-Mor-057288	Magnaporthe oryzae	43.19	4.00e-141	494.00
IUUC-Mpo-057594	Magnaporthe poae	39.88	4.00e-172	597.00
IUUC-Mtr-058700	Medicago truncatula	37.75	8.00e-173	600.00
IUUC-Mla-058846	Melampsora laricipopulina	41.72	6.00e-135	474.00
IUUC-Mga-059207	Meleagris gallopavo	43.24	0.00e+00	709.00
IUUC-Mvi-060327	Microbotryum violaceum	39.78	0.00e+00	706.00
IUUC-Mmr-061264	Microcebus murinus	47.39	0.00e+00	802.00
IUUC-Mdo-062327	Monodelphis domestica	46.80	0.00e+00	853.00
IUUC-Mmu-063542	Mus musculus	46.94	0.00e+00	811.00
IUUC-Mac-065142	Musa acuminata	36.91	6.00e-163	566.00
IUUC-Mpu-066098	Mustela putorius furo	45.30	0.00e+00	692.00
IUUC-Mlu-067056	Myotis lucifugus	43.33	0.00e+00	714.00
IUUC-Nfi-068323	Neosartorya fischeri	39.52	0.00e+00	672.00
IUUC-Ncr-068925	Neurospora crassa	39.27	0.00e+00	662.00
IUUC-Nle-068970	Nomascus leucogenys	46.88	0.00e+00	830.00
IUUC-Opr-070966	Ochotona princeps	56.48	2.00e-109	389.00
IUUC-Ont-071252	Oreochromis niloticus	46.55	0.00e+00	801.00
IUUC-Oan-072737	Ornithorhynchus anatinus	46.64	0.00e+00	825.00
IUUC-Oba-075794	Oryza barthii	37.84	3.00e-161	561.00
IUUC-Obr-076617	Oryza brachyantha	37.72	8.00e-166	577.00
IUUC-Ogl-077022	Oryza glaberrima	38.92	6.00e-171	593.00
IUUC-Ogu-078757	Oryza glumaepatula	35.96	2.00e-72	266.00
IUUC-Oin-079813	Oryza indica	38.92	7.00e-172	597.00
IUUC-Olo-080265	Oryza longistaminata	38.81	5.00e-167	580.00
IUUC-Ome-081494	Oryza meridionalis	38.70	5.00e-169	587.00
IUUC-Oni-082639	Oryza nivara	35.96	2.00e-72	266.00
IUUC-Opu-084005	Oryza punctata	38.41	3.00e-168	584.00
IUUC-Oru-084883	Oryza rufipogon	36.17	9.00e-73	267.00
IUUC-Osa-086158	Oryza sativa	38.81	2.00e-169	588.00
IUUC-Ola-086822	Oryzias latipes	46.15	0.00e+00	794.00
IUUC-Olu-087741	Ostreococcus lucimarinus	26.80	2.00e-17	80.50
IUUC-Oga-088887	Otolemur garnettii	47.83	0.00e+00	806.00
IUUC-Oar-090110	Ovis aries	46.29	0.00e+00	775.00
IUUC-Pan-092808	Papio anubis	47.61	0.00e+00	848.00
IUUC-Psi-093954	Pelodiscus sinensis	49.39	0.00e+00	873.00
IUUC-Pno-094922	Phaeosphaeria nodorum	36.83	5.00e-150	524.00
IUUC-Ppa-095678	Physcomitrella patens	36.56	4.00e-155	541.00
IUUC-Pfo-097175	Poecilia formosa	46.26	0.00e+00	809.00
IUUC-Pab-098155	Pongo abelii	46.77	0.00e+00	839.00
IUUC-Pop-099635	Populus trichocarpa	38.05	3.00e-171	595.00
IUUC-Pca-100947	Procavia capensis	44.16	0.00e+00	745.00
IUUC-Ppe-101552	Prunus persica	38.92	7.00e-176	610.00
IUUC-Pva-102744	Pteropus vampyrus	44.19	0.00e+00	742.00
IUUC-Pgr-103389	Puccinia graminis	39.40	0.00e+00	638.00
IUUC-Ptt-103953	Puccinia triticina	32.83	2.00e-142	499.00
IUUC-Pte-104079	Pyrenophora teres	36.68	5.00e-146	511.00
IUUC-Pyt-104656	Pyrenophora triticirepentis	36.76	9.00e-147	513.00
IUUC-Rno-105502	Rattus norvegicus	47.10	0.00e+00	833.00
IUUC-Sce-106390	Saccharomyces cerevisiae	39.23	0.00e+00	642.00
IUUC-Sha-107264	Sarcophilus harrisii	41.29	8.00e-91	326.00
IUUC-Sja-107674	Schizosaccharomyces japonicus	39.58	0.00e+00	676.00
IUUC-Spo-108348	Schizosaccharomyces pombe	40.00	0.00e+00	664.00
IUUC-Smo-108982	Selaginella moellendorffii	38.75	1.00e-171	596.00
IUUC-Sit-110304	Setaria italica	37.90	1.00e-177	616.00
IUUC-Sly-111620	Solanum lycopersicum	41.61	1.00e-127	449.00
IUUC-Stu-112877	Solanum tuberosum	37.96	7.00e-173	600.00
IUUC-Sbi-114702	Sorghum bicolor	38.70	2.00e-173	602.00
IUUC-Sre-115129	Sporisorium reilianum	37.17	7.00e-174	603.00
IUUC-Ssc-115931	Sus scrofa	45.57	9.00e-96	342.00
IUUC-Tgu-116787	Taeniopygia guttata	46.99	0.00e+00	826.00
IUUC-Tru-118218	Takifugu rubripes	44.23	0.00e+00	787.00
IUUC-Tsy-119401	Tarsius syrichta	47.39	2.00e-127	449.00
IUUC-Tni-120046	Tetraodon nigroviridis	43.49	0.00e+00	762.00
IUUC-Tca-121685	Theobroma cacao	38.60	7.00e-173	600.00
IUUC-Tre-122154	Trichoderma reesei	39.25	0.00e+00	644.00
IUUC-Tvi-122451	Trichoderma virens	38.29	2.00e-170	592.00
IUUC-Tae-125397	Triticum aestivum	40.29	1.00e-96	347.00
IUUC-Tur-126650	Triticum urartu	38.31	1.00e-154	539.00
IUUC-Tme-127005	Tuber melanosporum	46.74	6.00e-147	514.00
IUUC-Tbe-128102	Tupaia belangeri	45.92	2.00e-144	505.00
IUUC-Ttr-128259	Tursiops truncatus	47.79	0.00e+00	791.00
IUUC-Uma-129511	Ustilago maydis	37.72	2.00e-176	612.00
IUUC-Vda-129833	Verticillium dahliae	37.76	2.00e-169	588.00
IUUC-Vvi-131572	Vitis vinifera	37.19	5.00e-161	560.00
IUUC-Xtr-131776	Xenopus tropicalis	34.09	2.00e-51	196.00
IUUC-Xma-133887	Xiphophorus maculatus	46.37	0.00e+00	796.00
IUUC-Yli-134427	Yarrowia lipolytica	35.16	1.00e-150	526.00
IUUC-Zma-135980	Zea mays	38.81	4.00e-170	591.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence