iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E1	37.22	8.00e-109	389.00	IUUC-Sce-106413

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MSTEKEIILQ FAPWESFVSP TFWHKLAELK LDHDRLSDSK RSITGHYTNR NASGCLLEVD 60
YTAYNRMAKP PKFSHSAIGT IYNKNTIEEF KALDKLQLLA DEGKELLADM CSGGALRDPS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCATTGGTC TATCGCCATC GAGAGCTTTG TTTGTTTATA ATTTGCAGCC AAACGTTTGA 60
ACGTAAACAA CGCCCTAAGC AAAACATGAG CACGGAAAAA GAGATAATTT TGCAATTTGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome

Interpro

IPR006285--Atg7
IPR032197--Atg7_N
IPR016040--NAD(P)-bd_dom
IPR000594--ThiF_NAD_FAD-bd

Pfam

PF16420--ATG7_N
PF00899--ThiF

Gene Ontology

GO:0000407--C:pre-autophagosomal structure
GO:0019778--F:Atg12 activating enzyme activity
GO:0019779--F:Atg8 activating enzyme activity
GO:0000045--P:autophagosome assembly
GO:0006914--P:autophagy
GO:0006501--P:C-terminal protein lipidation
GO:0009267--P:cellular response to starvation
GO:0008340--P:determination of adult lifespan
GO:0035096--P:larval midgut cell programmed cell death
GO:0016236--P:macroautophagy
GO:0000422--P:mitophagy
GO:0043066--P:negative regulation of apoptotic process
GO:0060548--P:negative regulation of cell death
GO:0048477--P:oogenesis
GO:0016239--P:positive regulation of macroautophagy
GO:0006497--P:protein lipidation
GO:0032446--P:protein modification by small protein conjugation
GO:0010506--P:regulation of autophagy
GO:0050688--P:regulation of defense response to virus
GO:1903706--P:regulation of hemopoiesis

KEGG

dme:Dmel_CG5489

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000588	Aegilops tauschii	33.72	9.00e-85	308.00
IUUC-Aml-002316	Ailuropoda melanoleuca	41.32	6.00e-128	450.00
IUUC-Atr-002579	Amborella trichopoda	39.27	2.00e-130	459.00
IUUC-Apl-003805	Anas platyrhynchos	41.05	6.00e-143	500.00
IUUC-Aca-004618	Anolis carolinensis	41.21	6.00e-120	423.00
IUUC-Aly-005670	Arabidopsis lyrata	41.71	2.00e-118	419.00
IUUC-Ath-007499	Arabidopsis thaliana	41.74	4.00e-118	417.00
IUUC-Ago-007838	Ashbya gossypii	37.78	2.00e-105	375.00
IUUC-Acl-008093	Aspergillus clavatus	38.53	3.00e-127	448.00
IUUC-Afl-008663	Aspergillus flavus	39.97	8.00e-115	406.00
IUUC-Afu-008926	Aspergillus fumigatus	38.63	4.00e-126	444.00
IUUC-Ani-009156	Aspergillus nidulans	39.89	1.00e-125	442.00
IUUC-Ang-009853	Aspergillus niger	43.12	9.00e-52	195.00
IUUC-Aor-010055	Aspergillus oryzae	37.41	6.00e-127	447.00
IUUC-Ate-010281	Aspergillus terreus	33.19	6.00e-101	360.00
IUUC-Ame-010939	Astyanax mexicanus	40.64	8.00e-146	509.00
IUUC-Bgr-012006	Blumeria graminis	36.81	7.00e-125	440.00
IUUC-Bta-012336	Bos taurus	40.49	2.00e-133	468.00
IUUC-Bci-013598	Botrytis cinerea	37.45	3.00e-125	441.00
IUUC-Bdi-014170	Brachypodium distachyon	34.79	2.00e-86	313.00
IUUC-Bol-015357	Brassica oleracea	41.50	1.00e-125	442.00
IUUC-Bra-016835	Brassica rapa	41.79	3.00e-125	441.00
IUUC-Cel-018172	Caenorhabditis elegans	36.03	5.00e-111	394.00
IUUC-Cja-019544	Callithrix jacchus	41.03	2.00e-139	488.00
IUUC-Cfa-021043	Canis familiaris	40.34	2.00e-140	491.00
IUUC-Cpo-022366	Cavia porcellus	40.03	2.00e-140	491.00
IUUC-Cre-022945	Chlamydomonas reinhardtii	48.98	3.00e-66	245.00
IUUC-Csa-023373	Chlorocebus sabaeus	41.03	8.00e-140	489.00
IUUC-Cho-024965	Choloepus hoffmanni	46.39	1.00e-40	160.00
IUUC-Cin-025710	Ciona intestinalis	43.00	2.00e-152	532.00
IUUC-Cgl-026542	Colletotrichum gloeosporioides	37.45	4.00e-125	441.00
IUUC-Cne-027083	Cryptococcus neoformans	39.47	2.00e-113	402.00
IUUC-Dre-028740	Danio rerio	37.29	2.00e-123	436.00
IUUC-Dno-029637	Dasypus novemcinctus	41.99	2.00e-129	455.00
IUUC-Dor-030492	Dipodomys ordii	41.08	1.00e-140	492.00
IUUC-Dse-031267	Dothistroma septosporum	34.44	1.00e-114	406.00
IUUC-Ete-032616	Echinops telfairi	38.66	6.00e-123	434.00
IUUC-Eca-033991	Equus caballus	40.88	2.00e-140	492.00
IUUC-Eeu-035126	Erinaceus europaeus	54.12	3.00e-57	215.00
IUUC-Fca-035472	Felis catus	40.97	2.00e-141	495.00
IUUC-Fal-037178	Ficedula albicollis	40.93	1.00e-142	499.00
IUUC-Fox-037901	Fusarium oxysporum	39.97	1.00e-128	452.00
IUUC-Fso-038279	Fusarium solani	39.39	1.00e-129	456.00
IUUC-Gmo-039329	Gadus morhua	40.95	6.00e-140	490.00
IUUC-Ggr-040061	Gaeumannomyces graminis	38.47	5.00e-119	421.00
IUUC-Gga-040244	Gallus gallus	40.09	3.00e-144	504.00
IUUC-Gac-041880	Gasterosteus aculeatus	38.37	2.00e-133	469.00
IUUC-Gma-043235	Glycine max	39.20	4.00e-122	431.00
IUUC-Ggo-045428	Gorilla gorilla	40.46	5.00e-139	487.00
IUUC-Hsa-046183	Homo sapiens	40.74	3.00e-139	488.00
IUUC-Hvu-047509	Hordeum vulgare	33.53	1.00e-79	290.00
IUUC-Itr-048165	Ictidomys tridecemlineatus	41.04	2.00e-130	458.00
IUUC-Kpa-049142	Komagataella pastoris	38.73	3.00e-117	414.00
IUUC-Lch-049601	Latimeria chalumnae	34.34	2.00e-94	339.00
IUUC-Lpe-051496	Leersia perrieri	33.43	6.00e-83	301.00
IUUC-Loc-051751	Lepisosteus oculatus	40.51	9.00e-146	509.00
IUUC-Lma-053203	Leptosphaeria maculans	35.98	2.00e-88	319.00
IUUC-Laf-053424	Loxodonta africana	41.31	3.00e-143	501.00
IUUC-Mcc-054633	Macaca mulatta	41.17	5.00e-140	490.00
IUUC-Meu-056523	Macropus eugenii	36.95	2.00e-120	425.00
IUUC-Mor-056983	Magnaporthe oryzae	38.36	7.00e-129	453.00
IUUC-Mpo-057615	Magnaporthe poae	39.14	3.00e-129	455.00
IUUC-Mtr-058366	Medicago truncatula	38.74	8.00e-116	410.00
IUUC-Mla-058826	Melampsora laricipopulina	36.04	1.00e-119	422.00
IUUC-Mga-059447	Meleagris gallopavo	40.31	1.00e-144	505.00
IUUC-Mvi-060537	Microbotryum violaceum	40.00	7.00e-131	460.00
IUUC-Mmr-060676	Microcebus murinus	41.13	2.00e-140	492.00
IUUC-Mdo-062967	Monodelphis domestica	41.05	2.00e-137	482.00
IUUC-Mmu-063217	Mus musculus	40.74	5.00e-138	484.00
IUUC-Mac-065527	Musa acuminata	42.52	2.00e-125	442.00
IUUC-Mpu-066417	Mustela putorius furo	41.37	2.00e-140	491.00
IUUC-Mlu-067195	Myotis lucifugus	40.47	3.00e-141	494.00
IUUC-Nfi-068576	Neosartorya fischeri	37.57	4.00e-128	451.00
IUUC-Ncr-068867	Neurospora crassa	40.52	8.00e-126	443.00
IUUC-Nle-069447	Nomascus leucogenys	48.11	3.00e-93	334.00
IUUC-Opr-070737	Ochotona princeps	44.78	2.00e-104	372.00
IUUC-Ont-071260	Oreochromis niloticus	41.10	2.00e-141	495.00
IUUC-Oan-073622	Ornithorhynchus anatinus	38.70	3.00e-87	315.00
IUUC-Ocu-074584	Oryctolagus cuniculus	41.34	5.00e-144	504.00
IUUC-Oba-075483	Oryza barthii	33.38	2.00e-78	286.00
IUUC-Obr-076786	Oryza brachyantha	33.48	1.00e-86	313.00
IUUC-Ogl-077388	Oryza glaberrima	44.38	4.00e-77	282.00
IUUC-Ogu-078618	Oryza glumaepatula	33.97	4.00e-85	308.00
IUUC-Oin-080007	Oryza indica	33.67	4.00e-80	292.00
IUUC-Olo-080994	Oryza longistaminata	45.40	2.00e-78	286.00
IUUC-Ome-081735	Oryza meridionalis	33.53	2.00e-78	286.00
IUUC-Oni-082153	Oryza nivara	33.67	1.00e-79	290.00
IUUC-Opu-083146	Oryza punctata	45.27	4.00e-78	285.00
IUUC-Oru-084919	Oryza rufipogon	33.67	4.00e-80	292.00
IUUC-Osa-086182	Oryza sativa	33.62	2.00e-79	290.00
IUUC-Ola-086441	Oryzias latipes	42.51	3.00e-148	518.00
IUUC-Olu-087664	Ostreococcus lucimarinus	40.20	1.00e-113	402.00
IUUC-Oga-089074	Otolemur garnettii	40.92	2.00e-130	458.00
IUUC-Oar-090159	Ovis aries	40.97	7.00e-133	466.00
IUUC-Ptr-091105	Pan troglodytes	41.37	5.00e-119	420.00
IUUC-Pan-092446	Papio anubis	41.03	9.00e-140	489.00
IUUC-Psi-093372	Pelodiscus sinensis	40.09	5.00e-132	464.00
IUUC-Pma-094661	Petromyzon marinus	39.48	8.00e-121	426.00
IUUC-Pno-094813	Phaeosphaeria nodorum	32.92	5.00e-85	307.00
IUUC-Ppa-095224	Physcomitrella patens	40.54	9.00e-127	446.00
IUUC-Pfo-096565	Poecilia formosa	42.09	3.00e-140	491.00
IUUC-Pop-099702	Populus trichocarpa	40.56	3.00e-132	465.00
IUUC-Pca-100324	Procavia capensis	33.48	1.00e-64	240.00
IUUC-Ppe-101416	Prunus persica	39.68	2.00e-123	435.00
IUUC-Pva-102589	Pteropus vampyrus	38.32	6.00e-123	434.00
IUUC-Pgr-103497	Puccinia graminis	39.86	1.00e-132	466.00
IUUC-Ptt-103718	Puccinia triticina	40.00	2.00e-129	455.00
IUUC-Pte-104206	Pyrenophora teres	34.36	2.00e-83	301.00
IUUC-Pyt-104767	Pyrenophora triticirepentis	34.21	6.00e-98	350.00
IUUC-Rno-105911	Rattus norvegicus	40.57	2.00e-138	485.00
IUUC-Sce-106413	Saccharomyces cerevisiae	36.98	8.00e-112	396.00
IUUC-Sha-106679	Sarcophilus harrisii	41.28	1.00e-140	492.00
IUUC-Sja-107928	Schizosaccharomyces japonicus	36.43	4.00e-110	391.00
IUUC-Spo-108107	Schizosaccharomyces pombe	38.25	2.00e-113	402.00
IUUC-Ssl-108570	Sclerotinia sclerotiorum	38.46	8.00e-129	453.00
IUUC-Smo-109677	Selaginella moellendorffii	36.64	4.00e-104	371.00
IUUC-Sit-110319	Setaria italica	31.99	7.00e-77	281.00
IUUC-Sly-111215	Solanum lycopersicum	40.06	3.00e-129	454.00
IUUC-Stu-112442	Solanum tuberosum	40.66	1.00e-126	446.00
IUUC-Sar-113370	Sorex araneus	47.84	9.00e-104	370.00
IUUC-Sbi-114261	Sorghum bicolor	32.75	7.00e-86	311.00
IUUC-Sre-114997	Sporisorium reilianum	37.47	2.00e-122	432.00
IUUC-Ssc-115304	Sus scrofa	40.68	1.00e-134	473.00
IUUC-Tgu-117235	Taeniopygia guttata	41.65	3.00e-144	504.00
IUUC-Tru-118374	Takifugu rubripes	41.10	7.00e-139	486.00
IUUC-Tsy-118966	Tarsius syrichta	35.24	7.00e-101	360.00
IUUC-Tni-120269	Tetraodon nigroviridis	40.31	7.00e-126	443.00
IUUC-Tca-121245	Theobroma cacao	41.09	1.00e-134	473.00
IUUC-Tre-121966	Trichoderma reesei	38.73	2.00e-127	449.00
IUUC-Tvi-122360	Trichoderma virens	39.77	1.00e-125	442.00
IUUC-Tae-125251	Triticum aestivum	33.77	3.00e-87	315.00
IUUC-Tur-126294	Triticum urartu	33.62	2.00e-83	303.00
IUUC-Tme-127117	Tuber melanosporum	37.52	1.00e-119	422.00
IUUC-Tbe-127662	Tupaia belangeri	46.30	2.00e-46	180.00
IUUC-Ttr-129054	Tursiops truncatus	40.59	9.00e-139	486.00
IUUC-Uma-129526	Ustilago maydis	35.95	1.00e-120	426.00
IUUC-Vda-129878	Verticillium dahliae	38.57	2.00e-128	452.00
IUUC-Vpa-130264	Vicugna pacos	36.36	3.00e-66	245.00
IUUC-Vvi-131163	Vitis vinifera	39.43	7.00e-129	454.00
IUUC-Xtr-132328	Xenopus tropicalis	29.85	3.00e-78	285.00
IUUC-Xma-133015	Xiphophorus maculatus	40.49	1.00e-133	469.00
IUUC-Yli-134468	Yarrowia lipolytica	35.49	5.00e-112	397.00
IUUC-Zma-134871	Zea mays	35.02	4.00e-93	335.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence