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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Sce-106440
Ensembl Protein ID YPR007C
UniProt Accession Q12188; D6W418; REC8_YEAST
Genbank Protein ID AAA97586.1; CAA88785.1; CAA95047.1; DAA11434.1
Protein Name Meiotic recombination protein REC8; Cohesin REC8; Sporulation protein 69
Genbank Nucleotide ID U31900; Z48951; Z71255; BK006949
Gene Name REC8; SPO69; YPR007C; LPZ7C
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YPR007C YPR007C YPR007C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
iRefIndexMentha
Post-translational Modifications (PTMs)
dbPAFBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UFD/PB1 40.54 1.80e+00 26.90 IUUC-Ots-000022
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description



     Replaces the SCC1 mitosis-specific cohesin to ensure sister chromatid cohesion during meiosis. Is cleaved by ESP1 shortly before the first meiotic division, and dissociates from chromatin, allowing sister chromatids to segregate. Is protected from cleavage by SPO13.
Replaces the SCC1 mitosis-specific cohesin to ensure sister chromatid cohesion during meiosis. Is cleaved by ESP1 shortly before the first meiotic division, and dissociates from chromatin, allowing sister chromatids to segregate. Is protected from cleavage by SPO13.
Protein Sequence
(Fasta)
MAPLSLNFKD DKKYKGLTTV WLLSALGNSI VKESNNYYSN KSNSTGNISS STVKKKDIVN 60
ISIPKTCDEI QNFENDFSLR YISNLLYGVT ICYNKKTEYV LNDLNHLLVQ LQKNDVYAFK 120
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Protein Fasta Sequence



>IUUC-Sce-106440|ULD,PB1|Saccharomyces cerevisiae
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Nucleotide Sequence
(Fasta)
ATGGCACCTC TTTCGTTGAA CTTTAAAGAT GACAAGAAAT ATAAGGGCCT CACAACAGTG 60
TGGTTGCTTT CTGCGTTGGG AAATTCCATT GTAAAGGAAA GTAACAATTA TTATTCAAAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Sce-106440|ULD,PB1|Saccharomyces cerevisiae
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Sequence Source Ensembl
Keyword

KW-0137--Centromere
KW-0158--Chromosome
KW-0159--Chromosome partition
KW-0181--Complete proteome
KW-0469--Meiosis
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome

Interpro

IPR023093--Rad21/Rec8_C
IPR006910--Rad21_Rec8_N

Pfam

PF04825--Rad21_Rec8_N

Gene Ontology

GO:0000794--C:condensed nuclear chromosome
GO:0000780--C:condensed nuclear chromosome, centromeric region
GO:0000798--C:nuclear cohesin complex
GO:0003682--F:chromatin binding
GO:0006302--P:double-strand break repair
GO:0051177--P:meiotic sister chromatid cohesion
GO:0071459--P:protein localization to chromosome, centromeric region
GO:0007131--P:reciprocal meiotic recombination
GO:0007130--P:synaptonemal complex assembly

KEGG sce:YPR007C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Dme-031648 Drosophila melanogaster 32.79 2.20e-01 28.90
IUUC-Lch-049519 Latimeria chalumnae 47.62 8.80e-01 25.40
Created Date 25-Jun-2017

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