iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Tca-121033

Ensembl Protein ID

EOY14220

UniProt Accession

A0A061FA72; A0A061FA72_THECC

Genbank Protein ID

EOY14220.1

Protein Name

Defective in cullin neddylation protein

Genbank Nucleotide ID

CM001885

Gene Name

TCM_033511

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
TCM_033511	EOY14220	EOY14220

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/DCUN1	9.50e-83	277.8	55	241
UBD/Alpha-Helix/UBA	3.00e-06	28.1	10	46

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/DCUN1

   S: 2    skkkleelferYkdpqedligieglekfcedlgvdpediavLvlawkleaatlcefsreefldgltalgcdsieklqeklktleselkdeqkfkdiYrfaf 102
           ++++leel++rYkdp+ d+i+++g++ +c+dl+vdp+di++Lv++w+++a t+ce+s++ef+ gl+alg+ds+ek++e++ +++selkdeqkf++iY+faf
   Q: 55   DTRHLEELYNRYKDPYTDMILADGITLLCNDLQVDPQDIVMLVVSWHMKASTMCEYSKQEFFIGLQALGIDSLEKFRERISFMRSELKDEQKFREIYNFAF 155
           6799************************************************************************************************* PP
   S: 103  nfakdkgqksldldtaialwkLllaerefklldawlkfLeeekkksiskDtWnllLefskviakdlsnYdeegaWPvliDefveyl 188
            +ak+kgqksl+ldtai +w+Ll+ae++++l+d+w++fL+ +++k+is+DtW +lLef++++++ lsnYd+egaWP+liDefveyl
   Q: 156  GWAKEKGQKSLALDTAIGMWQLLFAEKQWPLVDHWCQFLQARHNKAISRDTWSQLLEFARTVDPALSNYDAEGAWPYLIDEFVEYL 241
           ************************************************************************************97 PP

UBD/Alpha-Helix/UBA

   S: 5    dkleqlve.MGFdreealqaLraannnleaAveyLld 40
           dk++q++  +G +++ alqaL a++++le A + +++
   Q: 10   DKVQQFMTiTGASEKIALQALKASDWHLEGAFDVFYS 46
           89*****************************998876 PP

Organism

Theobroma cacao

Functional Description
(View)

Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity.

Protein Sequence
(Fasta)

MHKLGRGHRD KVQQFMTITG ASEKIALQAL KASDWHLEGA FDVFYSQPQI KSYTDTRHLE 60
ELYNRYKDPY TDMILADGIT LLCNDLQVDP QDIVMLVVSW HMKASTMCEY SKQEFFIGLQ 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CTCTTTCTCT TTCTGTTTCG ACGCTTTTAG GGTTTTTATT TATTTTCCAC AATATACTCC 60
AAAATGGTTA GTTCTGTCTT TTCCTTTTTT TTTTTTTAAA GAAAGATTTT GGTGTGTTGT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR014764--DCN-prot
IPR005176--PONY_dom
IPR009060--UBA-like

PROSITE

PS51229--DCUN1

Pfam

PF03556--Cullin_binding

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000561	Aegilops tauschii	74.50	4.00e-118	416.00
IUUC-Aml-001879	Ailuropoda melanoleuca	43.90	4.00e-59	220.00
IUUC-Atr-002697	Amborella trichopoda	89.19	5.00e-57	211.00
IUUC-Apl-003933	Anas platyrhynchos	43.90	3.00e-58	217.00
IUUC-Aca-005269	Anolis carolinensis	42.51	2.00e-57	215.00
IUUC-Aly-006285	Arabidopsis lyrata	68.15	9.00e-98	348.00
IUUC-Ath-007531	Arabidopsis thaliana	77.11	4.00e-118	416.00
IUUC-Ago-007806	Ashbya gossypii	25.71	2.00e-17	82.00
IUUC-Acl-008172	Aspergillus clavatus	26.98	1.00e-24	105.00
IUUC-Afl-008569	Aspergillus flavus	29.08	4.00e-31	127.00
IUUC-Afu-009005	Aspergillus fumigatus	27.65	5.00e-19	86.70
IUUC-Ani-009241	Aspergillus nidulans	22.15	1.00e-19	89.40
IUUC-Ang-009664	Aspergillus niger	28.81	1.00e-26	112.00
IUUC-Aor-009902	Aspergillus oryzae	30.56	3.00e-12	63.20
IUUC-Ate-010414	Aspergillus terreus	27.49	4.00e-29	120.00
IUUC-Ame-011763	Astyanax mexicanus	44.72	3.00e-60	224.00
IUUC-Bgr-011991	Blumeria graminis	32.99	9.00e-20	89.70
IUUC-Bta-013561	Bos taurus	43.10	5.00e-54	202.00
IUUC-Bci-013824	Botrytis cinerea	33.73	3.00e-30	124.00
IUUC-Bdi-014138	Brachypodium distachyon	73.31	1.00e-116	411.00
IUUC-Bol-015564	Brassica oleracea	79.03	1.00e-120	424.00
IUUC-Bra-017111	Brassica rapa	78.23	1.00e-119	421.00
IUUC-Cel-018441	Caenorhabditis elegans	33.82	1.00e-40	159.00
IUUC-Cja-019502	Callithrix jacchus	43.90	3.00e-59	220.00
IUUC-Cfa-020523	Canis familiaris	43.53	1.00e-54	205.00
IUUC-Cpo-022196	Cavia porcellus	43.50	1.00e-58	218.00
IUUC-Cre-022620	Chlamydomonas reinhardtii	44.40	1.00e-62	232.00
IUUC-Csa-023551	Chlorocebus sabaeus	44.13	8.00e-60	222.00
IUUC-Cho-024373	Choloepus hoffmanni	43.50	3.00e-55	207.00
IUUC-Cin-025269	Ciona intestinalis	41.70	1.00e-59	221.00
IUUC-Csv-025976	Ciona savignyi	33.93	9.00e-35	139.00
IUUC-Cgl-026386	Colletotrichum gloeosporioides	31.40	4.00e-21	93.60
IUUC-Cne-026950	Cryptococcus neoformans	34.87	2.00e-35	142.00
IUUC-Cme-027199	Cyanidioschyzon merolae	31.50	2.00e-09	55.80
IUUC-Dre-028247	Danio rerio	44.72	3.00e-60	224.00
IUUC-Dno-028974	Dasypus novemcinctus	44.13	8.00e-60	222.00
IUUC-Dor-030143	Dipodomys ordii	43.50	2.00e-58	217.00
IUUC-Dse-031365	Dothistroma septosporum	27.82	4.00e-25	107.00
IUUC-Dme-032197	Drosophila melanogaster	40.17	6.00e-55	206.00
IUUC-Ete-032371	Echinops telfairi	43.90	4.00e-59	220.00
IUUC-Eca-033242	Equus caballus	43.90	4.00e-59	220.00
IUUC-Eeu-035317	Erinaceus europaeus	43.50	9.00e-59	219.00
IUUC-Fca-036061	Felis catus	43.72	3.00e-59	220.00
IUUC-Fal-036715	Ficedula albicollis	43.90	2.00e-58	218.00
IUUC-Fox-037884	Fusarium oxysporum	33.33	8.00e-15	72.40
IUUC-Fso-038150	Fusarium solani	28.78	4.00e-17	81.30
IUUC-Gmo-038885	Gadus morhua	43.90	7.00e-60	223.00
IUUC-Ggr-039959	Gaeumannomyces graminis	27.27	3.00e-15	76.30
IUUC-Gga-040935	Gallus gallus	43.72	3.00e-59	220.00
IUUC-Gac-041478	Gasterosteus aculeatus	43.90	2.00e-58	218.00
IUUC-Gma-043545	Glycine max	87.64	4.00e-138	482.00
IUUC-Ggo-044972	Gorilla gorilla	42.91	3.00e-58	217.00
IUUC-Hsa-046089	Homo sapiens	44.13	8.00e-60	222.00
IUUC-Hvu-047636	Hordeum vulgare	36.51	1.00e-20	92.00
IUUC-Itr-047902	Ictidomys tridecemlineatus	43.50	2.00e-57	214.00
IUUC-Kpa-049127	Komagataella pastoris	29.08	6.00e-27	113.00
IUUC-Lch-050600	Latimeria chalumnae	43.32	1.00e-59	222.00
IUUC-Lpe-051540	Leersia perrieri	76.92	2.00e-120	424.00
IUUC-Loc-052509	Lepisosteus oculatus	44.53	4.00e-60	223.00
IUUC-Lma-053103	Leptosphaeria maculans	29.76	3.00e-27	114.00
IUUC-Laf-053972	Loxodonta africana	44.31	5.00e-59	219.00
IUUC-Mcc-054700	Macaca mulatta	42.91	2.00e-58	218.00
IUUC-Meu-056791	Macropus eugenii	37.96	1.00e-43	168.00
IUUC-Mor-056909	Magnaporthe oryzae	27.41	4.00e-23	100.00
IUUC-Mpo-057299	Magnaporthe poae	27.68	6.00e-19	87.00
IUUC-Mtr-057964	Medicago truncatula	85.71	7.00e-136	475.00
IUUC-Mla-058990	Melampsora laricipopulina	25.45	1.00e-15	76.30
IUUC-Mga-060072	Meleagris gallopavo	44.31	1.00e-58	218.00
IUUC-Mvi-060312	Microbotryum violaceum	35.08	1.00e-39	155.00
IUUC-Mmr-060851	Microcebus murinus	43.90	5.00e-59	219.00
IUUC-Mdo-063074	Monodelphis domestica	43.90	2.00e-58	220.00
IUUC-Mmu-063816	Mus musculus	44.53	7.00e-60	222.00
IUUC-Mac-065016	Musa acuminata	86.34	9.00e-96	341.00
IUUC-Mpu-066870	Mustela putorius furo	43.53	1.00e-54	205.00
IUUC-Mlu-067701	Myotis lucifugus	43.50	4.00e-58	216.00
IUUC-Nfi-068610	Neosartorya fischeri	28.24	4.00e-19	86.70
IUUC-Ncr-068780	Neurospora crassa	23.88	2.00e-16	79.30
IUUC-Nle-069291	Nomascus leucogenys	44.13	8.00e-60	222.00
IUUC-Opr-070682	Ochotona princeps	42.02	3.00e-43	167.00
IUUC-Ont-071813	Oreochromis niloticus	43.90	4.00e-59	220.00
IUUC-Oan-073031	Ornithorhynchus anatinus	43.50	9.00e-59	219.00
IUUC-Ocu-074648	Oryctolagus cuniculus	43.90	4.00e-59	220.00
IUUC-Oba-074993	Oryza barthii	77.02	4.00e-121	426.00
IUUC-Obr-076341	Oryza brachyantha	75.81	2.00e-119	420.00
IUUC-Ogl-077099	Oryza glaberrima	77.02	4.00e-121	426.00
IUUC-Ogu-078285	Oryza glumaepatula	77.82	5.00e-122	429.00
IUUC-Oin-079441	Oryza indica	77.42	1.00e-121	427.00
IUUC-Olo-081037	Oryza longistaminata	77.42	1.00e-121	427.00
IUUC-Ome-081357	Oryza meridionalis	77.42	1.00e-121	427.00
IUUC-Oni-082632	Oryza nivara	77.02	6.00e-121	425.00
IUUC-Opu-083351	Oryza punctata	76.39	8.00e-113	398.00
IUUC-Oru-084306	Oryza rufipogon	77.42	1.00e-121	427.00
IUUC-Osa-085307	Oryza sativa	77.42	1.00e-121	427.00
IUUC-Ola-086868	Oryzias latipes	44.31	5.00e-60	223.00
IUUC-Olu-087646	Ostreococcus lucimarinus	43.90	1.00e-53	202.00
IUUC-Oga-089015	Otolemur garnettii	43.50	2.00e-58	218.00
IUUC-Oar-090405	Ovis aries	43.50	2.00e-58	218.00
IUUC-Ptr-090735	Pan troglodytes	43.90	4.00e-59	220.00
IUUC-Pan-092825	Papio anubis	42.91	1.00e-58	218.00
IUUC-Psi-093110	Pelodiscus sinensis	43.10	1.00e-53	201.00
IUUC-Pma-094196	Petromyzon marinus	40.32	8.00e-42	163.00
IUUC-Pno-095145	Phaeosphaeria nodorum	31.31	6.00e-22	97.10
IUUC-Ppa-095306	Physcomitrella patens	74.30	5.00e-117	412.00
IUUC-Pfo-097121	Poecilia formosa	43.09	7.00e-60	223.00
IUUC-Pab-098197	Pongo abelii	41.81	2.00e-52	198.00
IUUC-Pop-098821	Populus trichocarpa	92.68	2.00e-66	243.00
IUUC-Pca-100218	Procavia capensis	42.28	2.00e-57	214.00
IUUC-Ppe-102032	Prunus persica	88.00	1.00e-135	474.00
IUUC-Pva-102691	Pteropus vampyrus	43.72	7.00e-59	219.00
IUUC-Pgr-103633	Puccinia graminis	28.12	2.00e-21	95.10
IUUC-Ptt-103979	Puccinia triticina	34.78	2.00e-04	39.30
IUUC-Pyt-104428	Pyrenophora triticirepentis	27.14	8.00e-21	92.80
IUUC-Rno-105016	Rattus norvegicus	44.94	6.00e-60	223.00
IUUC-Sce-106358	Saccharomyces cerevisiae	24.71	3.00e-20	90.90
IUUC-Sha-106888	Sarcophilus harrisii	43.90	4.00e-59	220.00
IUUC-Sja-107938	Schizosaccharomyces japonicus	29.29	7.00e-22	96.70
IUUC-Spo-108207	Schizosaccharomyces pombe	35.83	3.00e-25	107.00
IUUC-Ssl-108410	Sclerotinia sclerotiorum	32.55	2.00e-30	125.00
IUUC-Smo-108750	Selaginella moellendorffii	66.39	7.00e-96	342.00
IUUC-Sit-110052	Setaria italica	77.29	6.00e-123	432.00
IUUC-Sly-111489	Solanum lycopersicum	84.82	1.00e-133	468.00
IUUC-Stu-112517	Solanum tuberosum	64.90	1.00e-99	355.00
IUUC-Sar-113509	Sorex araneus	43.60	3.00e-39	154.00
IUUC-Sbi-114113	Sorghum bicolor	76.49	1.00e-120	424.00
IUUC-Sre-115221	Sporisorium reilianum	24.91	7.00e-23	100.00
IUUC-Ssc-115547	Sus scrofa	44.13	8.00e-60	222.00
IUUC-Tgu-117196	Taeniopygia guttata	43.90	2.00e-58	218.00
IUUC-Tru-117740	Takifugu rubripes	44.90	3.00e-60	224.00
IUUC-Tsy-119599	Tarsius syrichta	43.90	4.00e-59	220.00
IUUC-Tni-120542	Tetraodon nigroviridis	44.40	1.00e-57	215.00
IUUC-Tre-121986	Trichoderma reesei	25.85	5.00e-20	90.90
IUUC-Tvi-122607	Trichoderma virens	30.98	6.00e-27	113.00
IUUC-Tae-125740	Triticum aestivum	64.04	2.00e-112	397.00
IUUC-Tur-126375	Triticum urartu	57.94	1.00e-107	382.00
IUUC-Tme-126878	Tuber melanosporum	31.10	1.00e-33	136.00
IUUC-Tbe-127429	Tupaia belangeri	42.02	2.00e-43	168.00
IUUC-Ttr-129086	Tursiops truncatus	40.24	1.00e-50	191.00
IUUC-Uma-129364	Ustilago maydis	26.49	6.00e-28	117.00
IUUC-Vda-129929	Verticillium dahliae	30.41	7.00e-19	87.40
IUUC-Vpa-130048	Vicugna pacos	37.80	2.00e-45	174.00
IUUC-Vvi-130834	Vitis vinifera	89.96	2.00e-142	497.00
IUUC-Xtr-131888	Xenopus tropicalis	43.09	5.00e-59	219.00
IUUC-Xma-134122	Xiphophorus maculatus	43.50	1.00e-60	225.00
IUUC-Yli-134595	Yarrowia lipolytica	32.20	7.00e-34	136.00
IUUC-Zma-135642	Zea mays	75.70	5.00e-120	422.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence