iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLM	dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/PHD	4.00e-10	40.1	619	677

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/PHD

   S: 3    vClvCgeggedek......slveCekCrewfHpaClkls....veeelpnsekwiCpkCrs 53
            C +Cge +++e+      +l+eC++C+e++Hp+Cl++      +eelpn+  w+CpkC +
   Q: 619  TCSLCGEVDQNEEtqdfekKLMECCICNEIVHPGCLQMDgeglLNEELPNC--WECPKCYQ 677
           7*********995555666***********************99*******..******76 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MEPEEERIRY SQRLRGTMRR RYEDDGISDD EIEGKRTFDL EEKLHTNKYN ANFVTFMEGK 60
DFNVEYIQRG GLRDPLIFKN SDGLGIKMPD PDFTVNDVKM CVGSRRMVDV MDVNTQKGIE 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGCTTCGGA AGCGGCTGTG ACCGTCTGAG GGTACCGAGA AGAGGGTGTT TCCCGCGGCC 60
GGGTTGGCCC GGGTTTCGGG CTGGGGCTGC TGACCGCCAG CTTGGGGGAG TAGCCGAGTG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0539--Nucleus
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001810--F-box_dom
IPR003347--JmjC_dom
IPR032675--L_dom-like
IPR006553--Leu-rich_rpt_Cys-con_subtyp
IPR019786--Zinc_finger_PHD-type_CS
IPR002857--Znf_CXXC
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51184--JMJC
PS51058--ZF_CXXC
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2

Pfam

PF00646--F-box
PF02373--JmjC
PF16866--PHD_4
PF02008--zf-CXXC

SMART

SM00558--JmjC
SM00367--LRR_CC
SM00249--PHD

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0008270--F:zinc ion binding
GO:0006303--P:double-strand break repair via nonhomologous end joining
GO:0070544--P:histone H3-K36 demethylation

KEGG

rno:361700

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002052	Ailuropoda melanoleuca	87.18	0.00e+00	1127.00
IUUC-Apl-003192	Anas platyrhynchos	78.39	0.00e+00	1051.00
IUUC-Aca-004576	Anolis carolinensis	83.83	0.00e+00	1892.00
IUUC-Ago-007912	Ashbya gossypii	37.24	4.00e-52	199.00
IUUC-Ame-011753	Astyanax mexicanus	51.96	0.00e+00	676.00
IUUC-Bta-012730	Bos taurus	85.28	0.00e+00	1831.00
IUUC-Bra-016717	Brassica rapa	23.77	3.00e-09	55.50
IUUC-Cel-018303	Caenorhabditis elegans	38.25	2.00e-79	290.00
IUUC-Cja-019030	Callithrix jacchus	97.42	0.00e+00	2108.00
IUUC-Cfa-020644	Canis familiaris	97.42	0.00e+00	2137.00
IUUC-Cpo-022055	Cavia porcellus	97.24	0.00e+00	2102.00
IUUC-Csa-023379	Chlorocebus sabaeus	97.29	0.00e+00	2076.00
IUUC-Cho-024541	Choloepus hoffmanni	75.48	0.00e+00	1403.00
IUUC-Cin-025140	Ciona intestinalis	61.09	3.00e-107	382.00
IUUC-Csv-025861	Ciona savignyi	58.59	8.00e-121	427.00
IUUC-Cne-026797	Cryptococcus neoformans	38.51	6.00e-59	222.00
IUUC-Dre-027763	Danio rerio	61.00	0.00e+00	833.00
IUUC-Dno-029268	Dasypus novemcinctus	96.47	0.00e+00	2084.00
IUUC-Dor-031142	Dipodomys ordii	96.37	0.00e+00	1008.00
IUUC-Dme-032039	Drosophila melanogaster	60.65	6.00e-125	442.00
IUUC-Ete-032467	Echinops telfairi	86.96	0.00e+00	1863.00
IUUC-Eca-033526	Equus caballus	96.82	0.00e+00	2103.00
IUUC-Eeu-035273	Erinaceus europaeus	83.06	0.00e+00	1409.00
IUUC-Fca-035532	Felis catus	97.21	0.00e+00	2072.00
IUUC-Fal-037140	Ficedula albicollis	87.04	0.00e+00	1921.00
IUUC-Gmo-038932	Gadus morhua	58.83	0.00e+00	792.00
IUUC-Gga-040418	Gallus gallus	83.41	0.00e+00	1092.00
IUUC-Gac-041674	Gasterosteus aculeatus	55.44	0.00e+00	1196.00
IUUC-Ggo-045330	Gorilla gorilla	92.95	0.00e+00	790.00
IUUC-Hsa-046180	Homo sapiens	97.25	0.00e+00	2125.00
IUUC-Itr-048198	Ictidomys tridecemlineatus	96.43	0.00e+00	1397.00
IUUC-Lch-049730	Latimeria chalumnae	59.25	0.00e+00	969.00
IUUC-Loc-051972	Lepisosteus oculatus	59.06	0.00e+00	775.00
IUUC-Laf-053939	Loxodonta africana	96.43	0.00e+00	2086.00
IUUC-Mcc-054600	Macaca mulatta	97.16	0.00e+00	2104.00
IUUC-Meu-056314	Macropus eugenii	90.97	0.00e+00	1184.00
IUUC-Mga-059549	Meleagris gallopavo	78.70	0.00e+00	1125.00
IUUC-Mmr-060865	Microcebus murinus	97.50	0.00e+00	2125.00
IUUC-Mdo-062567	Monodelphis domestica	94.06	0.00e+00	2060.00
IUUC-Mmu-063782	Mus musculus	99.05	0.00e+00	2170.00
IUUC-Mpu-066055	Mustela putorius furo	97.07	0.00e+00	2134.00
IUUC-Mlu-067228	Myotis lucifugus	89.24	0.00e+00	1132.00
IUUC-Nle-069668	Nomascus leucogenys	97.33	0.00e+00	2105.00
IUUC-Opr-070225	Ochotona princeps	95.59	0.00e+00	2063.00
IUUC-Ont-071349	Oreochromis niloticus	75.76	1.00e-174	607.00
IUUC-Oan-073668	Ornithorhynchus anatinus	80.50	0.00e+00	668.00
IUUC-Ocu-074710	Oryctolagus cuniculus	97.76	0.00e+00	2084.00
IUUC-Ola-087410	Oryzias latipes	57.96	0.00e+00	770.00
IUUC-Oga-088644	Otolemur garnettii	97.10	0.00e+00	2019.00
IUUC-Oar-089193	Ovis aries	95.83	0.00e+00	2046.00
IUUC-Ptr-091523	Pan troglodytes	97.25	0.00e+00	2125.00
IUUC-Pan-092415	Papio anubis	97.33	0.00e+00	2109.00
IUUC-Psi-093607	Pelodiscus sinensis	88.38	0.00e+00	1040.00
IUUC-Ppa-095609	Physcomitrella patens	37.58	4.00e-58	218.00
IUUC-Pfo-096695	Poecilia formosa	50.13	0.00e+00	1070.00
IUUC-Pab-098580	Pongo abelii	97.46	0.00e+00	1222.00
IUUC-Pca-100670	Procavia capensis	91.92	0.00e+00	1503.00
IUUC-Pva-102416	Pteropus vampyrus	90.52	0.00e+00	1906.00
IUUC-Pgr-103554	Puccinia graminis	44.67	4.00e-74	272.00
IUUC-Sce-106445	Saccharomyces cerevisiae	43.46	5.00e-50	192.00
IUUC-Sha-106693	Sarcophilus harrisii	93.73	0.00e+00	1940.00
IUUC-Spo-108120	Schizosaccharomyces pombe	33.90	2.00e-48	187.00
IUUC-Smo-109024	Selaginella moellendorffii	36.02	1.00e-58	220.00
IUUC-Sar-113568	Sorex araneus	93.55	0.00e+00	2000.00
IUUC-Sre-115112	Sporisorium reilianum	40.94	1.00e-59	224.00
IUUC-Ssc-116337	Sus scrofa	95.53	0.00e+00	1534.00
IUUC-Tgu-117298	Taeniopygia guttata	87.71	0.00e+00	1923.00
IUUC-Tru-118423	Takifugu rubripes	52.36	0.00e+00	1118.00
IUUC-Tsy-119293	Tarsius syrichta	95.59	0.00e+00	2018.00
IUUC-Tni-120020	Tetraodon nigroviridis	55.30	0.00e+00	760.00
IUUC-Tbe-127450	Tupaia belangeri	85.12	0.00e+00	1743.00
IUUC-Ttr-128837	Tursiops truncatus	86.75	0.00e+00	904.00
IUUC-Uma-129458	Ustilago maydis	38.60	3.00e-60	226.00
IUUC-Vpa-130655	Vicugna pacos	90.57	0.00e+00	1453.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence