iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033476

Ensembl Protein ID

ENSECAP00000019985.1

UniProt Accession

F7AXJ3; F7AXJ3_HORSE

Protein Name

Uncharacterized protein

Gene Name

SGSM3

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000022296.1	ENSECAT00000024077.1	ENSECAP00000019985.1
ENSECAG00000022296.1	ENSECAT00000024097.1	ENSECAP00000020003.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.50e-10	40.3	484	539

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 4    ekvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++ ++l d+e  +ddeL ++k d++++i   ++de  ++g  el+g rG fP+ Fve l+
   Q: 484  RRAKALLDFERHDDDELGFRKNDIITII--SQKDEHCWVG--ELNGLRGWFPAKFVEVLD 539
           56799***********************..777888888*..9**************987 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

ILGSHVPSAS GPFSALTPSM WPQEILAKYT QKEESEEQPE FYYDEFGFRV DKEDGADPSS 60
SKLPGVSLME DPPQRLRWQA HLEFTHNHDV GDLTWDKIAV SLPRSEKLRS LVLAGIPHSM 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTTTAGGAA GCCATGTGCC TTCTGCCAGT GGCCCCTTCT CAGCCCTAAC TCCAAGCATG 60
TGGCCTCAGG AGATCCTGGC CAAGTACACG CAGGTACAGC AATTTACCAG CACTCTGCTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR000195--Rab-GTPase-TBC_dom
IPR004012--Run_dom
IPR001452--SH3_domain

PROSITE

PS50826--RUN
PS50002--SH3
PS50086--TBC_RABGAP

Pfam

PF00566--RabGAP-TBC
PF02759--RUN
PF00018--SH3_1

SMART

SM00593--RUN
SM00326--SH3
SM00164--TBC

Gene Ontology

GO:0005829--C:cytosol
GO:0012505--C:endomembrane system
GO:0005622--C:intracellular
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0090630--P:activation of GTPase activity
GO:0006886--P:intracellular protein transport
GO:0048227--P:plasma membrane to endosome transport
GO:0032486--P:Rap protein signal transduction
GO:0032483--P:regulation of Rab protein signal transduction
GO:0031338--P:regulation of vesicle fusion

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aca-004863	Anolis carolinensis	87.47	0.00e+00	1332.00
IUUC-Cja-019526	Callithrix jacchus	91.45	0.00e+00	891.00
IUUC-Cfa-021075	Canis familiaris	96.66	0.00e+00	1446.00
IUUC-Dno-029715	Dasypus novemcinctus	92.68	0.00e+00	1396.00
IUUC-Dme-031891	Drosophila melanogaster	65.34	0.00e+00	1014.00
IUUC-Fca-035397	Felis catus	97.70	0.00e+00	854.00
IUUC-Laf-054163	Loxodonta africana	73.67	0.00e+00	1042.00
IUUC-Mcc-055074	Macaca mulatta	96.55	2.00e-152	531.00
IUUC-Mmu-063863	Mus musculus	94.79	0.00e+00	1397.00
IUUC-Mpu-065920	Mustela putorius furo	96.54	0.00e+00	1444.00
IUUC-Psi-093779	Pelodiscus sinensis	88.42	0.00e+00	1344.00
IUUC-Rno-105265	Rattus norvegicus	95.06	0.00e+00	1384.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence