iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-088406

Ensembl Protein ID

ENSOGAP00000004563.2

UniProt Accession

H0WRB8; H0WRB8_OTOGA

Genbank Protein ID

ENSOGAP00000004563

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03130611

Gene Name

UBASH3B

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000005102.2	ENSOGAT00000005105.2	ENSOGAP00000004563.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	8.00e-22	77.0	209	272
UBD/Alpha-Helix/UBA	4.40e-06	26.7	1	30

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 2    skekvqvlydyeaqnddeLtlkkGdvvlvi..ekeeqdegWlkgvkelegkrGlfPenFvekle 63
           ++e++qv+y+y++qnddeL+l  Gd++++   e+++++egW++g++ ++g++Gl+Pen+++k++
   Q: 209  NHETLQVIYPYTPQNDDELELVPGDFIFMSpmEQTSTSEGWIYGTSLTTGCSGLLPENYITKAD 272
           6899*********************************************************987 PP

UBD/Alpha-Helix/UBA

   S: 13   MGFdreealqaLraa.nnnleaAveyLldg 41
           MGF+r +a++aL+++ + +++ A+++L+++
   Q: 1    MGFPRARAQKALASTgGRSVQKACDWLFSH 30
           ****************************97 PP

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MGFPRARAQK ALASTGGRSV QKACDWLFSH VGDPFLDDPL PREYVLYLRP TGPLAQKLSD 60
FWQQSKQICG KNKAHNIFPH ITLCQFFMCE DSKVDALGEA LQTTVSRWKC KFSAPLPLEL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATTGCAAATT CCCGGACTGC TAGAAGCCGA GAAGGAGGGG GGCGGAGGAG CGAGGGCTAC 60
TGCGGGCGCA GTGCTGGGGA CAGCCGGGGC CAGAGTGGCC GACGGCCCGT CCCGCAGAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR009097--cNuc_Pdiesterase
IPR013078--His_Pase_superF_clade-1
IPR029033--His_PPase_superfam
IPR001452--SH3_domain
IPR015940--UBA
IPR009060--UBA-like

PROSITE

PS50002--SH3
PS50030--UBA

Pfam

PF00300--His_Phos_1
PF14604--SH3_9
PF00627--UBA

SMART

SM00326--SH3

Gene Ontology

GO:0004725--F:protein tyrosine phosphatase activity
GO:0045779--P:negative regulation of bone resorption
GO:0045671--P:negative regulation of osteoclast differentiation
GO:0090331--P:negative regulation of platelet aggregation
GO:0006469--P:negative regulation of protein kinase activity
GO:0009968--P:negative regulation of signal transduction
GO:0051279--P:regulation of release of sequestered calcium ion into cytosol

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002126	Ailuropoda melanoleuca	91.71	0.00e+00	1121.00
IUUC-Apl-004080	Anas platyrhynchos	86.26	0.00e+00	1039.00
IUUC-Aca-004828	Anolis carolinensis	84.67	0.00e+00	1041.00
IUUC-Ame-011030	Astyanax mexicanus	71.03	0.00e+00	796.00
IUUC-Bta-012370	Bos taurus	92.27	0.00e+00	1111.00
IUUC-Bci-013728	Botrytis cinerea	28.14	2.00e-10	60.10
IUUC-Cel-018530	Caenorhabditis elegans	39.30	2.00e-50	192.00
IUUC-Cja-018758	Callithrix jacchus	92.70	0.00e+00	1129.00
IUUC-Cfa-020544	Canis familiaris	91.46	0.00e+00	948.00
IUUC-Cpo-022044	Cavia porcellus	92.27	0.00e+00	1105.00
IUUC-Csa-024169	Chlorocebus sabaeus	92.54	0.00e+00	1125.00
IUUC-Cho-024498	Choloepus hoffmanni	74.62	0.00e+00	833.00
IUUC-Cin-025372	Ciona intestinalis	41.22	4.00e-58	219.00
IUUC-Csv-026379	Ciona savignyi	44.67	3.00e-70	258.00
IUUC-Cgl-026592	Colletotrichum gloeosporioides	29.59	3.00e-09	55.80
IUUC-Dre-027539	Danio rerio	72.20	0.00e+00	916.00
IUUC-Dno-029808	Dasypus novemcinctus	88.08	0.00e+00	642.00
IUUC-Dor-030582	Dipodomys ordii	96.20	9.00e-136	477.00
IUUC-Dme-032201	Drosophila melanogaster	39.63	4.00e-63	236.00
IUUC-Ete-032740	Echinops telfairi	72.64	0.00e+00	874.00
IUUC-Eca-033743	Equus caballus	92.87	0.00e+00	1134.00
IUUC-Eeu-034505	Erinaceus europaeus	78.32	3.00e-179	621.00
IUUC-Fca-036519	Felis catus	92.21	0.00e+00	1130.00
IUUC-Fal-037295	Ficedula albicollis	85.67	0.00e+00	1040.00
IUUC-Gmo-038650	Gadus morhua	71.29	0.00e+00	868.00
IUUC-Gga-040179	Gallus gallus	86.26	0.00e+00	1063.00
IUUC-Gac-042180	Gasterosteus aculeatus	70.54	0.00e+00	863.00
IUUC-Ggo-044581	Gorilla gorilla	92.70	0.00e+00	1128.00
IUUC-Hsa-046526	Homo sapiens	92.54	0.00e+00	1128.00
IUUC-Itr-048502	Ictidomys tridecemlineatus	97.12	7.00e-165	572.00
IUUC-Lch-049576	Latimeria chalumnae	78.74	0.00e+00	981.00
IUUC-Loc-051854	Lepisosteus oculatus	76.51	0.00e+00	890.00
IUUC-Laf-054177	Loxodonta africana	91.71	0.00e+00	1121.00
IUUC-Mcc-055185	Macaca mulatta	92.54	0.00e+00	1127.00
IUUC-Meu-056216	Macropus eugenii	87.66	0.00e+00	978.00
IUUC-Mga-059564	Meleagris gallopavo	85.91	0.00e+00	1041.00
IUUC-Mmr-060934	Microcebus murinus	92.70	0.00e+00	1127.00
IUUC-Mdo-062955	Monodelphis domestica	91.23	0.00e+00	1122.00
IUUC-Mmu-063301	Mus musculus	92.04	0.00e+00	1129.00
IUUC-Mpu-066416	Mustela putorius furo	92.37	0.00e+00	1131.00
IUUC-Mlu-067833	Myotis lucifugus	87.37	0.00e+00	1024.00
IUUC-Nle-069367	Nomascus leucogenys	92.04	0.00e+00	1120.00
IUUC-Opr-070879	Ochotona princeps	91.74	4.00e-131	461.00
IUUC-Ont-072540	Oreochromis niloticus	72.32	0.00e+00	870.00
IUUC-Oan-073124	Ornithorhynchus anatinus	83.92	0.00e+00	819.00
IUUC-Ocu-074796	Oryctolagus cuniculus	92.54	0.00e+00	1126.00
IUUC-Ola-087253	Oryzias latipes	70.68	0.00e+00	870.00
IUUC-Oar-090262	Ovis aries	92.21	0.00e+00	1125.00
IUUC-Ptr-091014	Pan troglodytes	92.70	0.00e+00	1128.00
IUUC-Pan-092684	Papio anubis	92.54	0.00e+00	1127.00
IUUC-Psi-093541	Pelodiscus sinensis	87.09	0.00e+00	1074.00
IUUC-Pma-094108	Petromyzon marinus	57.81	5.00e-159	553.00
IUUC-Pfo-097119	Poecilia formosa	70.52	0.00e+00	835.00
IUUC-Pab-097724	Pongo abelii	90.64	0.00e+00	1098.00
IUUC-Pca-100645	Procavia capensis	76.58	0.00e+00	720.00
IUUC-Pva-102322	Pteropus vampyrus	92.61	0.00e+00	1113.00
IUUC-Rno-105148	Rattus norvegicus	91.71	0.00e+00	1125.00
IUUC-Sha-106673	Sarcophilus harrisii	88.89	0.00e+00	1082.00
IUUC-Ssl-108385	Sclerotinia sclerotiorum	30.95	4.00e-09	55.50
IUUC-Sar-113746	Sorex araneus	77.43	1.00e-98	353.00
IUUC-Ssc-116425	Sus scrofa	92.70	0.00e+00	1130.00
IUUC-Tgu-116520	Taeniopygia guttata	85.10	0.00e+00	1045.00
IUUC-Tru-117750	Takifugu rubripes	66.45	0.00e+00	828.00
IUUC-Tsy-118975	Tarsius syrichta	92.41	0.00e+00	1088.00
IUUC-Tni-119830	Tetraodon nigroviridis	71.91	0.00e+00	842.00
IUUC-Ttr-129103	Tursiops truncatus	92.04	0.00e+00	1125.00
IUUC-Vpa-130720	Vicugna pacos	98.47	5.00e-113	401.00
IUUC-Xtr-132314	Xenopus tropicalis	81.16	0.00e+00	1002.00
IUUC-Xma-133939	Xiphophorus maculatus	70.24	0.00e+00	864.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence