iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037459

Ensembl Protein ID

ENSFALP00000015003.1

UniProt Accession

U3KIZ9; U3KIZ9_FICAL

Genbank Protein ID

ENSFALP00000015003

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01020543

Gene Name

RNF139

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000014388.1	ENSFALT00000015068.1	ENSFALP00000015003.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	9.20e-09	35.4	470	508

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlC 45
           CaiC+ +f +  +++pC+H fha Cl kw       + +++CP C
   Q: 470  CAICYHEFTTSARITPCNHYFHALCLRKW------LYIQDTCPMC 508
           ********999******************......********** PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

MIASAFLLAA TSVLVNYYAA LHINFHSAYY TPAFGIQIFL QKGPSLWMAL SVLQLTFGIG 60
YVTLLNMQSI YSQLIILDIL IPVIGLVVEL PLNVRQVLVF ISGLVLTLNT TAILVTKMKW 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATTGCCT CAGCGTTTCT GCTGGCTGCA ACTTCAGTGT TGGTGAATTA CTATGCTGCT 60
TTGCACATAA ACTTCCACAG TGCCTACTAC ACACCTGCAT TTGGAATTCA GATCTTCCTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR025754--TRC8_N_dom
IPR001841--Znf_RING
IPR011016--Znf_RING-CH
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF13705--TRC8_N
PF13639--zf-RING_2

SMART

SM00184--RING
SM00744--RINGv

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0016021--C:integral component of membrane
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0036503--P:ERAD pathway
GO:0008285--P:negative regulation of cell proliferation
GO:0017148--P:negative regulation of translation
GO:2000060--P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0031648--P:protein destabilization
GO:0060628--P:regulation of ER to Golgi vesicle-mediated transport
GO:0070613--P:regulation of protein processing

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002401	Ailuropoda melanoleuca	82.47	0.00e+00	946.00
IUUC-Apl-004214	Anas platyrhynchos	91.30	0.00e+00	1047.00
IUUC-Aca-005326	Anolis carolinensis	87.55	0.00e+00	971.00
IUUC-Ame-011687	Astyanax mexicanus	72.63	0.00e+00	827.00
IUUC-Bta-013394	Bos taurus	81.36	0.00e+00	969.00
IUUC-Cja-019499	Callithrix jacchus	80.31	0.00e+00	971.00
IUUC-Cfa-020357	Canis familiaris	81.83	0.00e+00	952.00
IUUC-Cpo-021924	Cavia porcellus	84.25	0.00e+00	991.00
IUUC-Csa-023513	Chlorocebus sabaeus	80.98	0.00e+00	964.00
IUUC-Cho-024285	Choloepus hoffmanni	74.92	0.00e+00	821.00
IUUC-Cin-025223	Ciona intestinalis	53.18	9.00e-74	269.00
IUUC-Csv-026018	Ciona savignyi	47.62	3.00e-65	241.00
IUUC-Dre-028660	Danio rerio	71.98	0.00e+00	743.00
IUUC-Dno-029463	Dasypus novemcinctus	86.36	3.00e-116	412.00
IUUC-Dor-030728	Dipodomys ordii	84.17	0.00e+00	943.00
IUUC-Dse-031284	Dothistroma septosporum	45.83	9.00e-09	53.90
IUUC-Dme-032186	Drosophila melanogaster	44.47	3.00e-99	356.00
IUUC-Ete-032368	Echinops telfairi	77.46	0.00e+00	947.00
IUUC-Eca-034325	Equus caballus	80.98	0.00e+00	947.00
IUUC-Fca-035537	Felis catus	82.67	0.00e+00	947.00
IUUC-Gmo-039442	Gadus morhua	78.36	3.00e-99	355.00
IUUC-Gga-041071	Gallus gallus	95.02	0.00e+00	1031.00
IUUC-Gac-042483	Gasterosteus aculeatus	72.24	0.00e+00	857.00
IUUC-Ggo-044672	Gorilla gorilla	80.81	0.00e+00	962.00
IUUC-Hsa-045836	Homo sapiens	80.75	0.00e+00	936.00
IUUC-Itr-048588	Ictidomys tridecemlineatus	83.57	0.00e+00	976.00
IUUC-Lch-050073	Latimeria chalumnae	78.93	0.00e+00	937.00
IUUC-Loc-052908	Lepisosteus oculatus	74.20	0.00e+00	904.00
IUUC-Laf-053519	Loxodonta africana	80.31	0.00e+00	978.00
IUUC-Mor-057262	Magnaporthe oryzae	34.52	8.00e-09	55.80
IUUC-Mga-059922	Meleagris gallopavo	93.81	0.00e+00	1012.00
IUUC-Mmr-061452	Microcebus murinus	80.48	0.00e+00	952.00
IUUC-Mdo-062412	Monodelphis domestica	81.96	0.00e+00	972.00
IUUC-Mmu-063147	Mus musculus	82.33	0.00e+00	974.00
IUUC-Mpu-065929	Mustela putorius furo	81.29	0.00e+00	949.00
IUUC-Mlu-067899	Myotis lucifugus	84.80	0.00e+00	932.00
IUUC-Nle-070083	Nomascus leucogenys	80.81	0.00e+00	963.00
IUUC-Opr-070461	Ochotona princeps	80.39	0.00e+00	946.00
IUUC-Ont-072256	Oreochromis niloticus	74.21	0.00e+00	841.00
IUUC-Oan-073150	Ornithorhynchus anatinus	82.23	0.00e+00	909.00
IUUC-Ocu-073748	Oryctolagus cuniculus	78.68	0.00e+00	922.00
IUUC-Oga-088565	Otolemur garnettii	83.87	0.00e+00	969.00
IUUC-Oar-089432	Ovis aries	81.36	0.00e+00	991.00
IUUC-Ptr-091422	Pan troglodytes	80.81	0.00e+00	961.00
IUUC-Pan-092331	Papio anubis	80.98	0.00e+00	964.00
IUUC-Psi-092933	Pelodiscus sinensis	90.19	0.00e+00	988.00
IUUC-Pfo-097466	Poecilia formosa	66.24	0.00e+00	852.00
IUUC-Pab-098702	Pongo abelii	80.81	0.00e+00	960.00
IUUC-Pca-100125	Procavia capensis	81.04	0.00e+00	966.00
IUUC-Pva-102628	Pteropus vampyrus	82.47	0.00e+00	948.00
IUUC-Rno-104886	Rattus norvegicus	83.04	0.00e+00	978.00
IUUC-Sha-106702	Sarcophilus harrisii	81.90	0.00e+00	968.00
IUUC-Ssc-115482	Sus scrofa	80.81	0.00e+00	966.00
IUUC-Tgu-116829	Taeniopygia guttata	97.59	0.00e+00	1077.00
IUUC-Tru-118557	Takifugu rubripes	70.93	0.00e+00	825.00
IUUC-Tsy-119399	Tarsius syrichta	79.24	4.00e-167	580.00
IUUC-Tni-120006	Tetraodon nigroviridis	64.13	0.00e+00	679.00
IUUC-Tbe-127664	Tupaia belangeri	82.82	0.00e+00	934.00
IUUC-Ttr-129144	Tursiops truncatus	85.02	0.00e+00	982.00
IUUC-Vpa-130226	Vicugna pacos	81.66	0.00e+00	969.00
IUUC-Vvi-131278	Vitis vinifera	42.59	1.00e-10	58.90
IUUC-Xtr-132461	Xenopus tropicalis	77.32	0.00e+00	875.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence