iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.00e-29	101.4	165	196
UBD/Beta-Prp	3.20e-58	197.3	102	422

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlr 31
           Htd+v+ l+f +  ++l+s+s+Dgt+k++D+ 
   Q: 165  HTDEVSYLEFhPKeHILASASRDGTVKLFDIA 196
           ***********776999*************75 PP

UBD/Beta-Prp

   S: 6    kghhksvitcvkfspdksllatgsrdgtikvwdvttgkl..................lrslsgheaevtavkfspdgkilvtgseDrtikvwdls..t 83
            ++hk+ +++ +fs d+sl+atgs d++ik+ dv+++ +                  +r+l++h++ev+ ++f+p++ il+++s+D+t+k++d+   +
   Q: 102  VTSHKQACRAGAFSCDGSLVATGSVDASIKILDVERMLAksapediepgreqqghpvIRTLYDHTDEVSYLEFHPKEHILASASRDGTVKLFDIAkpS 199
           5789999*****************************998*******************************************************9444 PP
   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqclee..tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltggh 179
            k  h++    + vl+lsf+p+gd++++G++++++rv+d+ t qc+ +  + ++h++ v+cv+++p+g+l+++Gs+D+ +++Wd  +g+++ t  ++h
   Q: 200  VKKAHKVFTDCEPVLCLSFHPTGDYVAIGTEHNVLRVYDVATTQCFVSaiPSQQHKAGVTCVKYSPTGKLYATGSYDGDIKIWDGISGRCINTIAEAH 297
           455666668999*************************************9********************************************8888 PP
   S: 180  td.svyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfs....pnderlvsgssDgsiri..Wdlrsgdllktlqlhnssvisv 270
            + ++ sl+f++ngk+l+s ++d+ v lw+l t++ ++t++g  ++ k+ + +    +++e +v   ++ + ++  W++r+g  l+  +l ++  +  
   Q: 298  GGaAICSLEFTRNGKYLLSSGMDSLVYLWELCTSRPIQTYTGAGTTGKQEHQTeavfNHTEDYVLFPDEATTSLcsWNSRNGCRLTLNSLGHNGPVRY 395
           7636999***********************************9988888776666669*********999888888******9999999999888888 PP
   S: 271  avlsfgdnvlvlgsedskvniwklkkn 297
            ++s++++ ++++s+d ++++w  + n
   Q: 396  ITHSPNGPAFLTCSDDFRARFWYRRAN 422
           889*******************98876 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MRDEILDPSN LVKNREILYR LMISQLMYDG LEKFAMELSM LVKADQCAPS ERLLHVMIAG 60
MQTLSDKDKT NSDDVLPGID LEFEPEASAL APEPHSYETA YVTSHKQACR AGAFSCDGSL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGTTTTCGAT AACGATAACG GCACGGCGTT ATCTACAAGA TTTTGTTTAT ATCCGTAGGA 60
AACAAAATAT AAATTAAGCC ACCATGCGTG ATGAGATTTT GGACCCCAGT AACCTAGTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR011042--6-blade_b-propeller_TolB-like
IPR024977--Apc4_WD40_dom
IPR032028--CSTF1_dimer
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF16699--CSTF1_dimer
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005848--C:mRNA cleavage stimulating factor complex
GO:0005654--C:nucleoplasm

KEGG

dme:Dmel_CG2261

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002163	Ailuropoda melanoleuca	55.34	1.00e-133	468.00
IUUC-Atr-002687	Amborella trichopoda	31.09	1.00e-55	209.00
IUUC-Apl-003438	Anas platyrhynchos	54.63	3.00e-132	464.00
IUUC-Aca-005178	Anolis carolinensis	54.82	1.00e-132	465.00
IUUC-Aly-005791	Arabidopsis lyrata	38.20	3.00e-70	258.00
IUUC-Ath-006689	Arabidopsis thaliana	38.20	2.00e-69	255.00
IUUC-Ame-011217	Astyanax mexicanus	55.40	7.00e-96	342.00
IUUC-Bta-012619	Bos taurus	55.11	3.00e-133	467.00
IUUC-Bdi-014515	Brachypodium distachyon	40.50	8.00e-68	249.00
IUUC-Bra-017450	Brassica rapa	36.49	1.00e-68	253.00
IUUC-Cel-018151	Caenorhabditis elegans	49.05	5.00e-120	423.00
IUUC-Cja-019304	Callithrix jacchus	55.11	2.00e-132	464.00
IUUC-Cfa-020208	Canis familiaris	55.34	1.00e-133	468.00
IUUC-Cpo-022245	Cavia porcellus	55.34	1.00e-133	468.00
IUUC-Csa-023066	Chlorocebus sabaeus	55.11	2.00e-132	464.00
IUUC-Cho-024770	Choloepus hoffmanni	57.98	2.00e-122	431.00
IUUC-Cin-025621	Ciona intestinalis	51.98	1.00e-123	435.00
IUUC-Csv-026071	Ciona savignyi	54.48	4.00e-129	453.00
IUUC-Dre-028254	Danio rerio	53.16	1.00e-127	449.00
IUUC-Dno-029903	Dasypus novemcinctus	55.34	1.00e-133	468.00
IUUC-Dor-030423	Dipodomys ordii	55.58	1.00e-133	469.00
IUUC-Ete-032689	Echinops telfairi	68.29	3.00e-31	128.00
IUUC-Eca-033316	Equus caballus	55.11	3.00e-133	467.00
IUUC-Eeu-035192	Erinaceus europaeus	53.21	9.00e-127	446.00
IUUC-Fca-036447	Felis catus	55.34	1.00e-133	468.00
IUUC-Fal-037601	Ficedula albicollis	54.63	3.00e-132	464.00
IUUC-Gmo-038531	Gadus morhua	53.27	8.00e-125	439.00
IUUC-Gga-040869	Gallus gallus	54.63	5.00e-132	463.00
IUUC-Gac-042380	Gasterosteus aculeatus	53.18	5.00e-126	443.00
IUUC-Gma-043478	Glycine max	34.70	2.00e-70	258.00
IUUC-Ggo-045302	Gorilla gorilla	55.11	2.00e-132	464.00
IUUC-Hsa-045678	Homo sapiens	55.11	2.00e-132	464.00
IUUC-Hvu-047301	Hordeum vulgare	40.92	2.00e-70	258.00
IUUC-Itr-048259	Ictidomys tridecemlineatus	55.34	1.00e-133	468.00
IUUC-Lch-050319	Latimeria chalumnae	54.01	5.00e-132	463.00
IUUC-Lpe-051440	Leersia perrieri	38.53	1.00e-56	213.00
IUUC-Loc-052035	Lepisosteus oculatus	54.01	1.00e-129	455.00
IUUC-Laf-054275	Loxodonta africana	55.34	1.00e-133	468.00
IUUC-Mcc-055857	Macaca mulatta	48.56	2.00e-108	384.00
IUUC-Meu-056194	Macropus eugenii	59.57	7.00e-41	159.00
IUUC-Mtr-058667	Medicago truncatula	32.17	5.00e-65	240.00
IUUC-Mga-059710	Meleagris gallopavo	54.63	5.00e-132	463.00
IUUC-Mmr-060604	Microcebus murinus	55.34	1.00e-133	468.00
IUUC-Mdo-062953	Monodelphis domestica	55.11	2.00e-133	468.00
IUUC-Mmu-064292	Mus musculus	55.11	2.00e-133	468.00
IUUC-Mac-064568	Musa acuminata	37.50	7.00e-67	246.00
IUUC-Mpu-066294	Mustela putorius furo	55.26	3.00e-76	278.00
IUUC-Mlu-067995	Myotis lucifugus	54.29	1.00e-132	465.00
IUUC-Nle-069322	Nomascus leucogenys	55.11	2.00e-132	464.00
IUUC-Opr-070580	Ochotona princeps	55.11	3.00e-133	467.00
IUUC-Ont-072554	Oreochromis niloticus	53.86	4.00e-130	457.00
IUUC-Oan-072856	Ornithorhynchus anatinus	55.11	2.00e-133	467.00
IUUC-Ocu-074150	Oryctolagus cuniculus	47.87	1.00e-103	369.00
IUUC-Oba-075585	Oryza barthii	36.29	1.00e-59	223.00
IUUC-Obr-076069	Oryza brachyantha	39.01	5.00e-65	240.00
IUUC-Ogl-077045	Oryza glaberrima	39.63	2.00e-68	252.00
IUUC-Ogu-078697	Oryza glumaepatula	39.68	5.00e-64	239.00
IUUC-Oin-080119	Oryza indica	39.63	2.00e-68	252.00
IUUC-Olo-081093	Oryza longistaminata	30.13	3.00e-38	153.00
IUUC-Ome-081718	Oryza meridionalis	33.13	1.00e-50	193.00
IUUC-Oni-082072	Oryza nivara	36.29	1.00e-59	223.00
IUUC-Opu-084080	Oryza punctata	33.75	6.00e-52	197.00
IUUC-Oru-085070	Oryza rufipogon	36.64	6.00e-60	225.00
IUUC-Osa-086149	Oryza sativa	39.63	2.00e-68	252.00
IUUC-Ola-086697	Oryzias latipes	53.16	3.00e-129	454.00
IUUC-Oga-088697	Otolemur garnettii	55.34	1.00e-133	468.00
IUUC-Oar-089774	Ovis aries	55.34	1.00e-133	468.00
IUUC-Ptr-090924	Pan troglodytes	55.11	2.00e-132	464.00
IUUC-Pan-092373	Papio anubis	55.11	1.00e-132	465.00
IUUC-Psi-094001	Pelodiscus sinensis	54.63	1.00e-131	462.00
IUUC-Pma-094274	Petromyzon marinus	55.40	1.00e-132	465.00
IUUC-Ppa-095562	Physcomitrella patens	41.05	1.00e-72	266.00
IUUC-Pfo-097235	Poecilia formosa	53.88	7.00e-130	456.00
IUUC-Pab-098608	Pongo abelii	55.11	2.00e-132	464.00
IUUC-Pca-100268	Procavia capensis	55.11	3.00e-133	467.00
IUUC-Ppe-101425	Prunus persica	39.75	2.00e-70	259.00
IUUC-Pva-103183	Pteropus vampyrus	55.34	1.00e-133	468.00
IUUC-Rno-105097	Rattus norvegicus	55.11	2.00e-133	468.00
IUUC-Sha-107642	Sarcophilus harrisii	55.11	2.00e-133	468.00
IUUC-Smo-108680	Selaginella moellendorffii	38.82	4.00e-66	244.00
IUUC-Sit-110471	Setaria italica	41.74	6.00e-70	258.00
IUUC-Sly-111143	Solanum lycopersicum	30.45	2.00e-28	118.00
IUUC-Stu-111926	Solanum tuberosum	39.49	2.00e-29	120.00
IUUC-Sar-112947	Sorex araneus	54.74	5.00e-85	306.00
IUUC-Sbi-113769	Sorghum bicolor	40.81	1.00e-69	256.00
IUUC-Ssc-115736	Sus scrofa	55.34	1.00e-133	468.00
IUUC-Tgu-117457	Taeniopygia guttata	54.63	3.00e-132	464.00
IUUC-Tru-117760	Takifugu rubripes	53.30	2.00e-129	454.00
IUUC-Tsy-118943	Tarsius syrichta	55.11	1.00e-130	458.00
IUUC-Tni-120081	Tetraodon nigroviridis	53.77	3.00e-130	457.00
IUUC-Tca-121190	Theobroma cacao	39.75	8.00e-70	256.00
IUUC-Tae-125535	Triticum aestivum	41.54	3.00e-72	265.00
IUUC-Tur-126329	Triticum urartu	41.23	3.00e-71	262.00
IUUC-Tbe-127878	Tupaia belangeri	54.68	6.00e-130	456.00
IUUC-Ttr-128985	Tursiops truncatus	55.34	1.00e-133	468.00
IUUC-Vpa-130147	Vicugna pacos	55.34	1.00e-133	468.00
IUUC-Vvi-130935	Vitis vinifera	38.51	6.00e-68	250.00
IUUC-Xtr-132482	Xenopus tropicalis	54.63	1.00e-131	462.00
IUUC-Xma-133929	Xiphophorus maculatus	53.88	7.00e-130	456.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence