iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Pab-098453

UUCD1 version

Ensembl Protein ID

UniProt Accession

Genbank Protein ID

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

ABGA01207099

Gene Name

USP43

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPPYG00000007972.2	ENSPPYT00000009330.2	ENSPPYP00000008964.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	2.00e-76	257.5	120	692

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 46   kgellkslqklfeelw..kskkkavsprellkalkkeaeefsgyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsde..a 130
            +e++++l+ l+++lw  +++ +  +  ++ +a++k+ ++f+g++q+Da Efl +lld+++e+l+ +++ p++e+   + +++s++  +
   Q: 120  RAEVTEQLAALVRALWtrEYTPQLSAEFKFQNAVSKYGSQFQGNSQHDALEFLLWLLDRVHEDLEGSSRGPVSEKLPPEATKTSENclS 208
           56899***********777777788888899*********************************9999999999988888888887778 PP
   S: 131  eekkkkknkslisdlFqgqlksqikclecdnvssreepfldlslpvpgkeetkke.................................. 185
           ++ +   ++s+++  Fq q++s+++c++c ++s++++pfl +slp+p ++++ ++                                  
   Q: 209  PSAQLPLGQSFVQSHFQAQYRSSLTCPHCLKQSNTFDPFLCVSLPIPLRQTRFLSvtlvfpsksqrflrvglavpilstvaalrkmvae 297
           89999999******************************************98888********************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 298  eggipadevilvelypsgfqrsffdeedlntiaegdnvyafqvppspspgtlsahplglsvsprlaaregqrfslslhseskvlilfcn 386
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 387  lvgsgqqasrfgppfliredravswaqlqqsilskvrhlmkseaplqnlgslfsirvvglsvacsylspkdsrplchwavdrvlhlrrp 475
           ***************************************************************************************** PP
   S: 186  ...............................................slqdcLesftkeeelegenkyycekckkkqeaekklklkklP 227
                                                          +l++c++ +tkee+l ++++++c++c+ +q+   kl+l++lP
   Q: 476  ggpphvklavewdssvkerlfgslqeeraqdadsvwqqqqahqqhscTLDECFQFYTKEEQLAQDDAWKCPHCQVLQQGMVKLSLWTLP 564
           ***************************************************************************************** PP
   S: 228  evLilhLkRfsfseeqksrekinkkvefple.Ldlspfctspeekqke....................kkkYeLiavvvHsGslssGHY 295
           ++Li+hLkRf   + +++r+k+++ v+fpl+ L+++p++++++++ +                     +  Y+L+av++H+G+l++GHY
   Q: 565  DILIIHLKRF--CQVGERRNKLSTLVKFPLSgLNMAPHVAQRSTSPEAglgpwpswkqpdclptsyplDFLYDLYAVCNHHGNLQGGHY 651
           **********..88899************************7777766999999999999999**999********************* PP
   S: 296  vayvkn.ekgkWllfdDskVtevkeeevleetgstaYvlfYkrr 338
           +ay++n  +g+W+ +dDs+V++++e+ev++   + aY+lfY++r
   Q: 652  TAYCRNsLDGQWYSYDDSTVEPLREDEVNT---RGAYILFYQKR 692
           ******55788*******************...********985 PP

Organism

Pongo abelii

Protein Sequence
(Fasta)

MDLGPGDAAG GGLLAPRPRR RRSLRRLFSR FLLALGSRSR PGDSPPRPQP GHCDGDGEGG 60
FACAPGPVPA APGSPGEERP PGPQPQLQLP AGDGARPPGA NTDLLAEFLA LGRYRAAPGR 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGACCTGG GCCCCGGGGA CGCGGCAGGA GGGGGACTGC TCGCGCCCCG GCCCCGCCGC 60
CGCCGCTCCC TGCGCCGCCT GTTCAGCCGC TTCCTGCTGG CGCTGGGCAG CCGCTCACGC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001922	Ailuropoda melanoleuca	77.14	0.00e+00	1389.00
IUUC-Aca-004436	Anolis carolinensis	53.92	0.00e+00	802.00
IUUC-Ame-011153	Astyanax mexicanus	49.54	0.00e+00	822.00
IUUC-Bta-013560	Bos taurus	79.11	0.00e+00	1519.00
IUUC-Cja-018737	Callithrix jacchus	90.59	0.00e+00	1808.00
IUUC-Cfa-020347	Canis familiaris	76.76	0.00e+00	1431.00
IUUC-Csa-023656	Chlorocebus sabaeus	97.42	0.00e+00	1880.00
IUUC-Cho-024864	Choloepus hoffmanni	71.10	0.00e+00	868.00
IUUC-Dre-028066	Danio rerio	49.07	0.00e+00	853.00
IUUC-Dno-028855	Dasypus novemcinctus	71.17	0.00e+00	1305.00
IUUC-Dor-030475	Dipodomys ordii	88.55	0.00e+00	724.00
IUUC-Dme-032088	Drosophila melanogaster	34.86	4.00e-95	343.00
IUUC-Eca-034147	Equus caballus	82.81	0.00e+00	1403.00
IUUC-Eeu-034703	Erinaceus europaeus	62.42	0.00e+00	758.00
IUUC-Fca-036550	Felis catus	74.49	0.00e+00	1258.00
IUUC-Gmo-038903	Gadus morhua	50.53	6.00e-178	617.00
IUUC-Gac-042087	Gasterosteus aculeatus	50.19	0.00e+00	848.00
IUUC-Ggo-045171	Gorilla gorilla	98.41	0.00e+00	1896.00
IUUC-Hsa-045961	Homo sapiens	96.93	0.00e+00	1907.00
IUUC-Itr-048673	Ictidomys tridecemlineatus	74.95	0.00e+00	684.00
IUUC-Loc-052852	Lepisosteus oculatus	62.05	0.00e+00	875.00
IUUC-Laf-054033	Loxodonta africana	76.52	0.00e+00	1490.00
IUUC-Mcc-055431	Macaca mulatta	96.72	0.00e+00	1885.00
IUUC-Mmr-061035	Microcebus murinus	86.11	0.00e+00	1619.00
IUUC-Mdo-062172	Monodelphis domestica	64.25	0.00e+00	917.00
IUUC-Mmu-063966	Mus musculus	78.06	0.00e+00	1506.00
IUUC-Mpu-066307	Mustela putorius furo	78.23	0.00e+00	1405.00
IUUC-Nle-070172	Nomascus leucogenys	96.28	0.00e+00	1902.00
IUUC-Opr-070499	Ochotona princeps	72.39	0.00e+00	1347.00
IUUC-Ont-071920	Oreochromis niloticus	51.82	0.00e+00	893.00
IUUC-Ocu-074014	Oryctolagus cuniculus	84.31	0.00e+00	1216.00
IUUC-Ola-086360	Oryzias latipes	52.04	0.00e+00	893.00
IUUC-Oga-088202	Otolemur garnettii	81.74	0.00e+00	1628.00
IUUC-Oar-089819	Ovis aries	77.54	0.00e+00	1477.00
IUUC-Ptr-091076	Pan troglodytes	96.55	0.00e+00	1899.00
IUUC-Pan-092248	Papio anubis	97.02	0.00e+00	1869.00
IUUC-Pfo-096534	Poecilia formosa	59.32	0.00e+00	766.00
IUUC-Pca-100290	Procavia capensis	63.39	0.00e+00	729.00
IUUC-Pva-102317	Pteropus vampyrus	72.16	0.00e+00	1351.00
IUUC-Rno-104948	Rattus norvegicus	78.26	0.00e+00	1409.00
IUUC-Sha-106558	Sarcophilus harrisii	55.38	0.00e+00	1083.00
IUUC-Sar-113105	Sorex araneus	63.88	0.00e+00	1058.00
IUUC-Ssc-115312	Sus scrofa	77.57	0.00e+00	1493.00
IUUC-Tru-117995	Takifugu rubripes	52.61	0.00e+00	885.00
IUUC-Tsy-119325	Tarsius syrichta	77.98	0.00e+00	771.00
IUUC-Tni-120517	Tetraodon nigroviridis	57.09	0.00e+00	810.00
IUUC-Tbe-127439	Tupaia belangeri	71.68	5.00e-144	504.00
IUUC-Ttr-128829	Tursiops truncatus	71.24	0.00e+00	1346.00
IUUC-Vpa-130306	Vicugna pacos	76.83	9.00e-168	584.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence