iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 activity/RING/RING	42.81	4.00e-147	518.00	IUUC-Cel-018432
E3 activity/RING/RING	45.27	7.00e-164	575.00	IUUC-Hsa-046503
E3 activity/RING/RING	46.36	9.00e-166	580.00	IUUC-Rno-105306

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MEDELRCPTC KQLYANPVLL PCFHALCLGC ALDIQTPYSP GSALPGAVNG AGAASAAGHN 60
GLHGNGGGAG GGAAAPVTNP NGPGTRHSSH SSAASTASSN TGSESVTSDQ DQSDKVSIFS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTCGTTCA AAAATCTCAA GCGGATCGGT CGTGTTGCGG ATGCCCAAAA TCGAAATTGG 60
TCGCGTTCAA AAGTTAGGCG CGTAATCAAA GTGGCAAGAA AGTTGAATAG AAAGAAAACA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR001870--B30.2/SPRY
IPR003649--Bbox_C
IPR013320--ConA-like_dom
IPR017903--COS_domain
IPR003961--FN3_dom
IPR013783--Ig-like_fold
IPR003877--SPRY_dom
IPR000315--Znf_B-box
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50188--B302_SPRY
PS51262--COS
PS50853--FN3
PS50119--ZF_BBOX

Pfam

PF00041--fn3
PF00622--SPRY
PF00643--zf-B_box

SMART

SM00502--BBC
SM00336--BBOX
SM00060--FN3
SM00184--RING
SM00449--SPRY

Gene Ontology

GO:0005622--C:intracellular
GO:0004842--F:ubiquitin-protein transferase activity
GO:0008270--F:zinc ion binding
GO:0007411--P:axon guidance
GO:0016199--P:axon midline choice point recognition
GO:0007409--P:axonogenesis
GO:0038007--P:netrin-activated signaling pathway
GO:0022008--P:neurogenesis
GO:0043161--P:proteasome-mediated ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002033	Ailuropoda melanoleuca	49.54	8.00e-130	456.00
IUUC-Apl-004004	Anas platyrhynchos	47.83	7.00e-165	573.00
IUUC-Aca-004773	Anolis carolinensis	41.11	2.00e-153	535.00
IUUC-Ame-011429	Astyanax mexicanus	39.91	5.00e-133	467.00
IUUC-Bta-013184	Bos taurus	42.63	2.00e-179	622.00
IUUC-Cel-018432	Caenorhabditis elegans	42.73	1.00e-144	506.00
IUUC-Cja-019517	Callithrix jacchus	43.23	1.00e-152	532.00
IUUC-Cfa-020240	Canis familiaris	41.40	4.00e-151	527.00
IUUC-Cpo-022321	Cavia porcellus	42.46	7.00e-150	523.00
IUUC-Csa-024114	Chlorocebus sabaeus	41.58	2.00e-153	535.00
IUUC-Cho-024399	Choloepus hoffmanni	49.83	4.00e-79	288.00
IUUC-Cin-025387	Ciona intestinalis	41.83	3.00e-139	488.00
IUUC-Csv-025851	Ciona savignyi	39.78	9.00e-139	486.00
IUUC-Dre-027691	Danio rerio	44.93	8.00e-168	583.00
IUUC-Dno-029047	Dasypus novemcinctus	42.63	2.00e-180	625.00
IUUC-Dor-030823	Dipodomys ordii	37.75	2.00e-77	283.00
IUUC-Ete-032674	Echinops telfairi	39.69	6.00e-134	470.00
IUUC-Eca-034107	Equus caballus	39.92	2.00e-157	548.00
IUUC-Eeu-034755	Erinaceus europaeus	55.32	2.00e-77	282.00
IUUC-Fca-036046	Felis catus	39.10	6.00e-110	390.00
IUUC-Fal-036997	Ficedula albicollis	46.76	3.00e-133	468.00
IUUC-Gmo-039639	Gadus morhua	44.13	2.00e-144	505.00
IUUC-Gga-040951	Gallus gallus	48.36	2.00e-169	588.00
IUUC-Gac-041390	Gasterosteus aculeatus	38.43	1.00e-151	529.00
IUUC-Ggo-044878	Gorilla gorilla	41.69	2.00e-152	531.00
IUUC-Hsa-046503	Homo sapiens	44.96	2.00e-170	591.00
IUUC-Itr-047884	Ictidomys tridecemlineatus	42.25	2.00e-155	542.00
IUUC-Lch-049521	Latimeria chalumnae	44.66	7.00e-105	374.00
IUUC-Loc-052458	Lepisosteus oculatus	40.62	4.00e-169	587.00
IUUC-Laf-054442	Loxodonta africana	42.37	2.00e-178	618.00
IUUC-Mcc-054887	Macaca mulatta	41.71	2.00e-176	611.00
IUUC-Meu-056251	Macropus eugenii	34.86	7.00e-97	347.00
IUUC-Mga-059961	Meleagris gallopavo	46.48	4.00e-131	460.00
IUUC-Mmr-061677	Microcebus murinus	42.37	4.00e-179	620.00
IUUC-Mdo-062608	Monodelphis domestica	40.58	7.00e-132	463.00
IUUC-Mmu-063314	Mus musculus	45.07	9.00e-156	543.00
IUUC-Mpu-065904	Mustela putorius furo	41.67	3.00e-152	531.00
IUUC-Mlu-067137	Myotis lucifugus	42.50	1.00e-179	622.00
IUUC-Nle-070127	Nomascus leucogenys	41.84	6.00e-177	613.00
IUUC-Opr-070450	Ochotona princeps	41.19	8.00e-140	490.00
IUUC-Ont-071416	Oreochromis niloticus	45.32	4.00e-168	583.00
IUUC-Oan-073661	Ornithorhynchus anatinus	51.91	5.00e-67	246.00
IUUC-Ocu-074651	Oryctolagus cuniculus	41.64	2.00e-152	532.00
IUUC-Ola-086349	Oryzias latipes	50.96	7.00e-58	215.00
IUUC-Oga-088823	Otolemur garnettii	40.94	5.00e-150	524.00
IUUC-Oar-089807	Ovis aries	42.25	6.00e-176	610.00
IUUC-Ptr-091267	Pan troglodytes	41.69	2.00e-152	531.00
IUUC-Pan-092803	Papio anubis	41.42	2.00e-150	525.00
IUUC-Psi-093885	Pelodiscus sinensis	49.15	6.00e-139	486.00
IUUC-Pma-094534	Petromyzon marinus	21.85	1.00e-07	49.70
IUUC-Pfo-096684	Poecilia formosa	44.73	1.00e-166	579.00
IUUC-Pab-097638	Pongo abelii	41.84	3.00e-176	611.00
IUUC-Pca-101102	Procavia capensis	39.00	7.00e-116	410.00
IUUC-Pva-103059	Pteropus vampyrus	54.79	7.00e-62	231.00
IUUC-Rno-105306	Rattus norvegicus	48.63	5.00e-171	593.00
IUUC-Sha-106771	Sarcophilus harrisii	47.58	9.00e-135	473.00
IUUC-Sar-113278	Sorex araneus	40.09	2.00e-134	471.00
IUUC-Ssc-115634	Sus scrofa	42.37	2.00e-179	621.00
IUUC-Tgu-117319	Taeniopygia guttata	43.94	5.00e-149	520.00
IUUC-Tru-117583	Takifugu rubripes	44.21	2.00e-165	575.00
IUUC-Tsy-119427	Tarsius syrichta	46.12	5.00e-66	244.00
IUUC-Tni-120847	Tetraodon nigroviridis	43.98	1.00e-164	572.00
IUUC-Tbe-127239	Tupaia belangeri	45.07	5.00e-82	297.00
IUUC-Ttr-128462	Tursiops truncatus	41.40	3.00e-90	324.00
IUUC-Vpa-130241	Vicugna pacos	44.31	3.00e-102	365.00
IUUC-Xtr-131998	Xenopus tropicalis	44.96	3.00e-165	574.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence