iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Eca-033367

Ensembl Protein ID

ENSECAP00000009489.1

UniProt Accession

F7B9Q9; F7B9Q9_HORSE

Protein Name

Uncharacterized protein

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSECAG00000011667.1	ENSECAT00000012057.1	ENSECAP00000009489.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	2.70e-16	59.4	423	479

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g  Gl P+n+ve ++
   Q: 423  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDNGTVGLYPANYVEAIQ 479
           799************************.9**********.59*************9885 PP

Organism

Equus caballus

Protein Sequence
(Fasta)

MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCTD LMNCLHERAR IEKAYAQQLT 60
EWARRWRQLV EKGPQYGTVE KAWIAVMSEA ERVSELHLEV RAALMNKDFE KIKNWQKEAF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TAAGCGTTCC CTGCTGCTCC CTCACCCTTT GAAGAGATGT CGGTCACTTA TGATGACTCC 60
GTTGGAGTAG AAGTGTCCAG CGATAGCTTC TGGGAGGTAA TGCCCGTGCT TTCTTCCTGA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome
GO:0030100--P:regulation of endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	93.62	0.00e+00	864.00
IUUC-Apl-003574	Anas platyrhynchos	85.57	0.00e+00	769.00
IUUC-Aca-004251	Anolis carolinensis	80.75	0.00e+00	746.00
IUUC-Ame-011756	Astyanax mexicanus	67.12	0.00e+00	681.00
IUUC-Bta-013193	Bos taurus	90.53	0.00e+00	811.00
IUUC-Cel-018168	Caenorhabditis elegans	31.11	2.00e-60	226.00
IUUC-Cja-018756	Callithrix jacchus	91.36	0.00e+00	831.00
IUUC-Cfa-020545	Canis familiaris	93.62	0.00e+00	893.00
IUUC-Cpo-022000	Cavia porcellus	87.24	0.00e+00	885.00
IUUC-Csa-024030	Chlorocebus sabaeus	89.66	0.00e+00	740.00
IUUC-Cin-025707	Ciona intestinalis	42.95	1.00e-105	376.00
IUUC-Csv-026244	Ciona savignyi	42.59	3.00e-53	201.00
IUUC-Dre-028104	Danio rerio	63.69	3.00e-165	574.00
IUUC-Dno-029429	Dasypus novemcinctus	89.62	0.00e+00	797.00
IUUC-Dor-030122	Dipodomys ordii	84.77	0.00e+00	762.00
IUUC-Dme-032120	Drosophila melanogaster	42.57	2.00e-104	372.00
IUUC-Eeu-034821	Erinaceus europaeus	76.34	0.00e+00	678.00
IUUC-Fca-036079	Felis catus	93.38	0.00e+00	857.00
IUUC-Fal-036682	Ficedula albicollis	85.47	0.00e+00	765.00
IUUC-Gmo-039681	Gadus morhua	64.52	6.00e-153	533.00
IUUC-Gga-040717	Gallus gallus	85.47	0.00e+00	768.00
IUUC-Gac-042262	Gasterosteus aculeatus	65.15	1.00e-172	599.00
IUUC-Ggo-044841	Gorilla gorilla	90.74	0.00e+00	799.00
IUUC-Hsa-046411	Homo sapiens	90.74	0.00e+00	799.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	90.74	0.00e+00	815.00
IUUC-Lch-050070	Latimeria chalumnae	65.10	8.00e-177	613.00
IUUC-Loc-051975	Lepisosteus oculatus	69.83	0.00e+00	678.00
IUUC-Laf-053839	Loxodonta africana	87.68	0.00e+00	833.00
IUUC-Mcc-055783	Macaca mulatta	90.74	0.00e+00	800.00
IUUC-Mga-060087	Meleagris gallopavo	80.34	0.00e+00	702.00
IUUC-Mmr-060827	Microcebus murinus	91.98	0.00e+00	846.00
IUUC-Mmu-064109	Mus musculus	91.56	0.00e+00	840.00
IUUC-Mpu-066591	Mustela putorius furo	94.03	0.00e+00	869.00
IUUC-Mlu-067826	Myotis lucifugus	93.62	0.00e+00	863.00
IUUC-Nle-069797	Nomascus leucogenys	91.15	0.00e+00	802.00
IUUC-Ont-072188	Oreochromis niloticus	62.58	1.00e-166	579.00
IUUC-Oan-073076	Ornithorhynchus anatinus	85.80	4.00e-159	553.00
IUUC-Ocu-074425	Oryctolagus cuniculus	91.93	0.00e+00	818.00
IUUC-Ola-087556	Oryzias latipes	65.88	1.00e-166	579.00
IUUC-Oga-089009	Otolemur garnettii	84.57	0.00e+00	778.00
IUUC-Oar-089806	Ovis aries	90.95	0.00e+00	815.00
IUUC-Ptr-091111	Pan troglodytes	90.33	0.00e+00	794.00
IUUC-Pan-091749	Papio anubis	88.38	0.00e+00	789.00
IUUC-Psi-093704	Pelodiscus sinensis	85.90	0.00e+00	781.00
IUUC-Pfo-096680	Poecilia formosa	64.72	3.00e-170	591.00
IUUC-Pab-098584	Pongo abelii	88.64	8.00e-155	539.00
IUUC-Pva-102649	Pteropus vampyrus	91.77	0.00e+00	821.00
IUUC-Pgr-103636	Puccinia graminis	41.82	2.00e-09	55.50
IUUC-Rno-105431	Rattus norvegicus	90.57	0.00e+00	864.00
IUUC-Sha-106641	Sarcophilus harrisii	88.20	0.00e+00	803.00
IUUC-Sar-113461	Sorex araneus	79.84	0.00e+00	712.00
IUUC-Ssc-115349	Sus scrofa	92.99	0.00e+00	830.00
IUUC-Tgu-116876	Taeniopygia guttata	85.47	0.00e+00	766.00
IUUC-Tru-118306	Takifugu rubripes	67.88	2.00e-176	612.00
IUUC-Tsy-118901	Tarsius syrichta	82.69	2.00e-152	531.00
IUUC-Tni-120120	Tetraodon nigroviridis	68.11	9.00e-180	622.00
IUUC-Xtr-132925	Xenopus tropicalis	80.70	0.00e+00	748.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence