iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fca-036079

Ensembl Protein ID

ENSFCAP00000009374.2

UniProt Accession

M3WCP1; M3WCP1_FELCA

Genbank Protein ID

ENSFCAP00000009374

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AANG02167075

Gene Name

PACSIN2

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFCAG00000010098.2	ENSFCAT00000010101.2	ENSFCAP00000009374.2

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	7.00e-17	61.2	412	468

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 5    kvqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           +v++lydye+q+ deL++k+Gd ++ i ++e ++gW+kg + ++g+ Gl P+n+ve ++
   Q: 412  RVRALYDYEGQEHDELSFKAGDELTKI-EDEDEQGWCKG-RLDNGQVGLYPANYVEAIQ 468
           799************************.9**********.59*************9885 PP

Organism

Felis catus

Protein Sequence
(Fasta)

WQVGNYKRTV KRIDDGHRLC SDLMNCLHER ARIEKAYAQQ LTEWARRWRQ LVEKGPQYGT 60
VEKAWTAVMA EAERVSELHL EVKASLMNED FEKIKNWQKE AFHKQMMGGF KETKEAEDGF 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

TGGCAGGGCA GTATTTGCAG GTGCAAAACA CCTGCTGTGT TGCCTGGCAC ATAGTAGGTG 60
CTCAGAAGGT GGGAGAGTAT TGAGGGCTGT AATCGGGAAG TGATAATAAT CCAGCATGGG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0728--SH3 domain

Interpro

IPR031160--F_BAR
IPR001060--FCH_dom
IPR028521--PACSIN2
IPR001452--SH3_domain

PROSITE

PS51741--F_BAR
PS50002--SH3

Pfam

PF00611--FCH
PF00018--SH3_1

PRINTS

PR00452--SH3DOMAIN

SMART

SM00055--FCH
SM00326--SH3

Gene Ontology

GO:0005901--C:caveola
GO:0005911--C:cell-cell junction
GO:0005829--C:cytosol
GO:0005768--C:endosome
GO:0070062--C:extracellular exosome
GO:0019898--C:extrinsic component of membrane
GO:0005925--C:focal adhesion
GO:0016607--C:nuclear speck
GO:0055038--C:recycling endosome membrane
GO:0070300--F:phosphatidic acid binding
GO:0030036--P:actin cytoskeleton organization
GO:0070836--P:caveola assembly
GO:0072584--P:caveolin-mediated endocytosis
GO:0048858--P:cell projection morphogenesis
GO:0045806--P:negative regulation of endocytosis
GO:0097320--P:plasma membrane tubulation
GO:0036010--P:protein localization to endosome
GO:0030100--P:regulation of endocytosis

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001887	Ailuropoda melanoleuca	97.44	0.00e+00	898.00
IUUC-Apl-003574	Anas platyrhynchos	86.97	0.00e+00	786.00
IUUC-Aca-004251	Anolis carolinensis	85.26	0.00e+00	762.00
IUUC-Ame-011756	Astyanax mexicanus	67.14	0.00e+00	663.00
IUUC-Bta-013193	Bos taurus	92.95	0.00e+00	832.00
IUUC-Cja-018756	Callithrix jacchus	95.09	0.00e+00	820.00
IUUC-Cfa-020545	Canis familiaris	97.65	0.00e+00	901.00
IUUC-Cpo-022000	Cavia porcellus	89.32	0.00e+00	877.00
IUUC-Csa-024030	Chlorocebus sabaeus	93.48	0.00e+00	760.00
IUUC-Cin-025707	Ciona intestinalis	42.25	3.00e-103	368.00
IUUC-Csv-026244	Ciona savignyi	42.70	2.00e-54	205.00
IUUC-Dre-028104	Danio rerio	63.60	1.00e-162	566.00
IUUC-Dno-029429	Dasypus novemcinctus	94.49	0.00e+00	819.00
IUUC-Dor-030122	Dipodomys ordii	86.32	0.00e+00	775.00
IUUC-Dme-032120	Drosophila melanogaster	43.22	9.00e-106	377.00
IUUC-Eca-033367	Equus caballus	93.38	0.00e+00	856.00
IUUC-Eeu-034821	Erinaceus europaeus	76.92	0.00e+00	689.00
IUUC-Fal-036682	Ficedula albicollis	87.18	0.00e+00	786.00
IUUC-Gmo-039681	Gadus morhua	65.18	9.00e-152	529.00
IUUC-Gga-040717	Gallus gallus	87.18	0.00e+00	787.00
IUUC-Gac-042262	Gasterosteus aculeatus	64.54	6.00e-169	586.00
IUUC-Ggo-044841	Gorilla gorilla	94.44	0.00e+00	813.00
IUUC-Hsa-046411	Homo sapiens	94.44	0.00e+00	814.00
IUUC-Itr-049063	Ictidomys tridecemlineatus	94.02	0.00e+00	833.00
IUUC-Loc-051975	Lepisosteus oculatus	71.49	0.00e+00	701.00
IUUC-Laf-053839	Loxodonta africana	93.36	0.00e+00	850.00
IUUC-Mcc-055783	Macaca mulatta	93.80	0.00e+00	810.00
IUUC-Mga-060087	Meleagris gallopavo	81.20	0.00e+00	714.00
IUUC-Mmr-060827	Microcebus murinus	93.80	0.00e+00	861.00
IUUC-Mmu-064109	Mus musculus	93.16	0.00e+00	855.00
IUUC-Mpu-066591	Mustela putorius furo	97.65	0.00e+00	900.00
IUUC-Mlu-067826	Myotis lucifugus	96.15	0.00e+00	887.00
IUUC-Nle-069797	Nomascus leucogenys	94.23	0.00e+00	811.00
IUUC-Oan-073076	Ornithorhynchus anatinus	85.51	5.00e-160	556.00
IUUC-Ocu-074425	Oryctolagus cuniculus	93.80	0.00e+00	834.00
IUUC-Ola-087556	Oryzias latipes	65.59	3.00e-162	565.00
IUUC-Oga-089009	Otolemur garnettii	87.17	0.00e+00	796.00
IUUC-Oar-089806	Ovis aries	93.59	0.00e+00	837.00
IUUC-Ptr-091111	Pan troglodytes	94.02	0.00e+00	809.00
IUUC-Pan-091749	Papio anubis	93.78	0.00e+00	803.00
IUUC-Psi-093704	Pelodiscus sinensis	88.27	0.00e+00	805.00
IUUC-Pfo-096680	Poecilia formosa	63.64	2.00e-166	578.00
IUUC-Pab-098584	Pongo abelii	94.30	6.00e-161	560.00
IUUC-Pva-102649	Pteropus vampyrus	95.09	0.00e+00	853.00
IUUC-Rno-105431	Rattus norvegicus	92.55	0.00e+00	881.00
IUUC-Sha-106641	Sarcophilus harrisii	91.42	0.00e+00	837.00
IUUC-Sar-113461	Sorex araneus	82.26	0.00e+00	738.00
IUUC-Ssc-115349	Sus scrofa	96.15	0.00e+00	853.00
IUUC-Tgu-116876	Taeniopygia guttata	87.18	0.00e+00	786.00
IUUC-Tru-118306	Takifugu rubripes	67.84	7.00e-173	600.00
IUUC-Tsy-118901	Tarsius syrichta	84.78	1.00e-157	549.00
IUUC-Tni-120120	Tetraodon nigroviridis	68.50	5.00e-176	610.00
IUUC-Xtr-132925	Xenopus tropicalis	82.52	0.00e+00	763.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence