iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sha-106629

Ensembl Protein ID

ENSSHAP00000010751.1

UniProt Accession

G3W5P6; G3W5P6_SARHA

Genbank Protein ID

ENSSHAP00000010751

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AEFK01005655

Gene Name

FBXW4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSSHAG00000009269.1	ENSSHAT00000010845.1	ENSSHAP00000010751.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.70e-18	66.2	111	139
UBD/Beta-Prp	3.90e-40	138.0	182	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    HtdsvtclafsdtllvsGsdDgtikvWDl 30
           H+ +v+c++ +++ +vsGs+D t kvW++
   Q: 111  HEQEVNCVDCQGGVIVSGSRDRTAKVWSI 139
           99*******95599*************96 PP

UBD/Beta-Prp

   S: 161  vrlWdlktgkllrtltgghtdsvyslsfdsng.kelvsgsldgtvklwdlq..tgecvrtlng.htdnvksvrfspnderlvsgs.sDg 244
           +r+Wdl +g+l+++l  + ++    l++ ++    l+s+++d+++++wd++  +++cv+++++ h++  ++vr +  ++ l+sgs   g
   Q: 182  LRIWDLTSGQLMTHLGRDFHRGAGVLDVLYETpSTLLSCGYDTYIRYWDIRtsSQKCVMEWEEpHDSALYCVRSD-GNHMLASGSsYYG 269
           79*************66677777777755555499****************9999*******9899999999988.999*****9789* PP
   S: 245  siriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvniwkl 294
           ++r+Wd r++ +l++++l+  ++++v +l+f+  +l+++ + s ++++++
   Q: 270  VVRLWDRRQKGCLHAFSLSSPTSSPVYCLRFSTTHLYAAVA-SALHVLDF 318
           ********************************999998866.56666666 PP

Organism

Sarcophilus harrisii

Protein Sequence
(Fasta)

IPVKERVKVS QNWRRGRCRQ GTLLKWRRNL MPWMQLEGGC LYLSQAEDIH AYQLCPDGSS 60
LHRRPLAIFS GHEEDVCRFV LASSHVVSGG GDGKIGLHKI NGTFSIKFSA HEQEVNCVDC 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CAGTATTCAC AATAAAAAGA ATATTAGACT TGGAATTATA AAAGTTATAT TCTTTTTTTT 60
GTTGTTTTTT CCCTAGCTGT ATGACCACGA GACAGCCTTG CTAAGCTTTA TTCTTCTCAT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0051216--P:cartilage development
GO:0042733--P:embryonic digit morphogenesis
GO:0002053--P:positive regulation of mesenchymal cell proliferation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002129	Ailuropoda melanoleuca	77.64	4.00e-155	540.00
IUUC-Apl-003837	Anas platyrhynchos	82.24	1.00e-161	561.00
IUUC-Aca-004776	Anolis carolinensis	78.44	8.00e-138	483.00
IUUC-Ame-010651	Astyanax mexicanus	63.86	6.00e-119	420.00
IUUC-Bta-013495	Bos taurus	77.02	4.00e-146	510.00
IUUC-Cja-018901	Callithrix jacchus	77.33	4.00e-146	510.00
IUUC-Cfa-021251	Canis familiaris	77.33	5.00e-154	537.00
IUUC-Cpo-021750	Cavia porcellus	78.57	4.00e-156	543.00
IUUC-Csa-024026	Chlorocebus sabaeus	77.02	1.00e-153	536.00
IUUC-Cho-024496	Choloepus hoffmanni	57.45	1.00e-103	369.00
IUUC-Cin-025142	Ciona intestinalis	31.72	3.00e-19	88.60
IUUC-Csv-025883	Ciona savignyi	38.14	1.00e-62	233.00
IUUC-Dre-027447	Danio rerio	61.88	3.00e-118	418.00
IUUC-Dno-029572	Dasypus novemcinctus	70.46	1.00e-131	463.00
IUUC-Dor-030982	Dipodomys ordii	77.40	1.00e-139	489.00
IUUC-Dme-031804	Drosophila melanogaster	20.86	3.00e-10	59.70
IUUC-Ete-032917	Echinops telfairi	77.33	1.00e-154	538.00
IUUC-Eca-033969	Equus caballus	77.33	2.00e-146	511.00
IUUC-Eeu-034850	Erinaceus europaeus	71.12	1.00e-134	473.00
IUUC-Fca-036182	Felis catus	77.64	8.00e-155	539.00
IUUC-Fal-037391	Ficedula albicollis	81.45	2.00e-152	531.00
IUUC-Gmo-038632	Gadus morhua	60.75	1.00e-115	409.00
IUUC-Gga-040783	Gallus gallus	81.76	4.00e-158	550.00
IUUC-Gac-042314	Gasterosteus aculeatus	58.31	5.00e-96	344.00
IUUC-Ggo-044739	Gorilla gorilla	77.64	5.00e-154	536.00
IUUC-Hsa-046705	Homo sapiens	77.64	3.00e-146	511.00
IUUC-Itr-048014	Ictidomys tridecemlineatus	77.51	5.00e-138	483.00
IUUC-Loc-052397	Lepisosteus oculatus	74.77	5.00e-139	487.00
IUUC-Laf-054544	Loxodonta africana	78.09	9.00e-155	539.00
IUUC-Meu-056363	Macropus eugenii	71.65	8.00e-120	422.00
IUUC-Mga-059275	Meleagris gallopavo	82.08	2.00e-159	554.00
IUUC-Mmr-060906	Microcebus murinus	76.71	1.00e-152	533.00
IUUC-Mdo-062400	Monodelphis domestica	98.13	0.00e+00	650.00
IUUC-Mmu-063556	Mus musculus	77.33	1.00e-153	536.00
IUUC-Mpu-066500	Mustela putorius furo	77.33	2.00e-154	538.00
IUUC-Mlu-068074	Myotis lucifugus	77.64	5.00e-155	540.00
IUUC-Nle-069601	Nomascus leucogenys	77.64	5.00e-154	536.00
IUUC-Opr-070904	Ochotona princeps	69.36	6.00e-98	350.00
IUUC-Ont-072679	Oreochromis niloticus	57.50	6.00e-112	397.00
IUUC-Oan-073434	Ornithorhynchus anatinus	85.21	2.00e-77	281.00
IUUC-Ocu-074649	Oryctolagus cuniculus	77.95	2.00e-155	541.00
IUUC-Ola-087336	Oryzias latipes	52.81	8.00e-90	323.00
IUUC-Oga-088590	Otolemur garnettii	75.47	1.00e-142	499.00
IUUC-Oar-090178	Ovis aries	77.33	9.00e-146	509.00
IUUC-Pan-092881	Papio anubis	77.02	2.00e-153	535.00
IUUC-Pfo-096176	Poecilia formosa	59.06	4.00e-101	361.00
IUUC-Pab-098285	Pongo abelii	77.64	6.00e-154	537.00
IUUC-Pca-100888	Procavia capensis	72.98	1.00e-138	486.00
IUUC-Pva-102184	Pteropus vampyrus	64.60	2.00e-119	421.00
IUUC-Rno-105668	Rattus norvegicus	77.02	1.00e-153	535.00
IUUC-Ssc-116183	Sus scrofa	78.26	1.00e-155	543.00
IUUC-Tgu-116630	Taeniopygia guttata	81.76	4.00e-158	550.00
IUUC-Tru-118761	Takifugu rubripes	55.17	1.00e-102	365.00
IUUC-Tni-120651	Tetraodon nigroviridis	52.48	2.00e-61	228.00
IUUC-Ttr-128582	Tursiops truncatus	77.33	2.00e-144	504.00
IUUC-Vpa-130431	Vicugna pacos	62.34	4.00e-80	291.00
IUUC-Xtr-132655	Xenopus tropicalis	73.44	3.00e-142	498.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence