iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Tru-118585

UUCD1 version

UUC-TaR-01108

Ensembl Protein ID

ENSTRUP00000035470.1

UniProt Accession

H2UEV1; H2UEV1_TAKRU

Protein Name

Ubiquitin carboxyl-terminal hydrolase

Gene Name

bap1

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSTRUG00000013867.1	ENSTRUT00000035597.1	ENSTRUP00000035469.1
ENSTRUG00000013867.1	ENSTRUT00000035598.1	ENSTRUP00000035470.1
ENSTRUG00000013867.1	ENSTRUT00000035599.1	ENSTRUP00000035471.1
ENSTRUG00000013867.1	ENSTRUT00000035600.1	ENSTRUP00000035472.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/UCH	5.40e-160	533.7	3	725

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/UCH

   S: 6    kewleLesdPglftllvedfgvkrdiqveelysLdpenlglyqepvegllllFkinekressrksqvtsndlevvdediiktiffakqv 94
           k+wleLesdPglftllvedfgvk++ qvee+y+L++++    q pv+g+++lFk++e+r+s+rk+++++++++v+de+i++ +ffa+q+
   Q: 3    KGWLELESDPGLFTLLVEDFGVKGV-QVEEIYDLQSKC----QSPVYGFIFLFKWIEERRSRRKVNTLVDETSVIDEEIVNDMFFAHQL 86
           89***********************.************....*********************************************** PP
   S: 95   igNsCatyAllsvllncedklldlGttlsrlkestkaespenkalalgnqqvlecihnslariesrseperqdedneqytkeafhfvsy 183
           i+NsCat+Allsvllnc+ +  +lGttlsr+k +tk++spe+k++a+gn+++l+ +hns+ar+e+r++pe+q++ ++++t+eafhfvsy
   Q: 87   IPNSCATHALLSVLLNCSGV--ELGTTLSRIKAFTKGFSPESKGYAIGNAPELARAHNSHARPEPRHLPEKQNGISAVRTMEAFHFVSY 173
           ******************99..9****************************************************************** PP
   S: 184  vningrlyeldglkpfPldlgkkketeelkdklkvvraflerikllesde....irfnllaivadrrviktlrlnvlkid......... 259
           v+i++rl+eldglk++P+d+g+++e+ee++dk+++v+  +eri+l++++e    irfnl+a+v+drr++++ +l++lk +         
   Q: 174  VPIKDRLFELDGLKAYPIDHGPWGEEEEWTDKARRVI--MERIGLATAGEpyhdIRFNLMAVVPDRRIKYESKLEILKKNrqiileglq 260
           *************************************..************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 261  kmirltqtelvhekkekdssspddstpaikkeaesepvpaqstdqapsdsvaesgaqskeatspsenimgkpsvpkgggppqvtspnpi 349
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 350  vqrlpafldnhnyakspmqeeediaagvgrtrmsappqppysddeddyedeeeevtgsavtsnrfrrkaslrsrtgrvgtgvesqialt 438
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 439  vlaeklkkeaqrkdalntplsvrtegrtggicitsasqpsptpsnestdtaseigsafnsplrsparsqaatrpsspvashlsrvlfge 527
           ***************************************************************************************** PP
   S: 260  ......................................................................................... 259
                                                                                                    
   Q: 528  demlrldsrhnravrelglsvstallhlqedgvifavppsveltadcskqpcthektkdkgkaslipkekegvnegdegpsvsletvdn 616
           ***************************************************************************************** PP
   S: 260  .........keLlkLlkdieseeekieaqlddekekrkkfkiddirRtenydeficifikdlaregilrklveetisevrefgvnegrl 339
                    keLl+Llk++e+ ++++e +l++e+ekrkk+kidd+rRt+nydefic+fi++la+eg+l+ lve++is++r++gv++grl
   Q: 617  kpagdkyspKELLALLKCVEADIANYEVSLKEEVEKRKKYKIDDQRRTHNYDEFICTFISMLAQEGMLASLVEQNISVRRRQGVSIGRL 705
           ***************************************************************************************** PP
   S: 340  akqrkqgrekkirplkrkrk 359
           +kqrk++r+k++rp+k+kr+
   Q: 706  HKQRKPDRRKRSRPYKAKRQ 725
           ******************97 PP

Organism

Takifugu rubripes

Protein Sequence
(Fasta)

MNKGWLELES DPGLFTLLVE DFGVKGVQVE EIYDLQSKCQ SPVYGFIFLF KWIEERRSRR 60
KVNTLVDETS VIDEEIVNDM FFAHQLIPNS CATHALLSVL LNCSGVELGT TLSRIKAFTK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAACAAAG GTTGGCTGGA GCTTGAGAGT GATCCAGGTA AGGATTTTCG TAAGAAAACA 60
CAGCTAAACA ACGTTAGCTT CCACATAAAG CCAGATCCAC ACTTGAGCTT CCTTAAGCAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-0645--Protease
KW-1185--Reference proteome
KW-0788--Thiol protease
KW-0833--Ubl conjugation pathway

Interpro

IPR001578--Peptidase_C12_UCH

Pfam

PF01088--Peptidase_C12

PRINTS

PR00707--UBCTHYDRLASE

Gene Ontology

GO:0005737--C:cytoplasm
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001263	Ailuropoda melanoleuca	66.53	0.00e+00	882.00
IUUC-Apl-003405	Anas platyrhynchos	53.60	7.00e-129	454.00
IUUC-Aca-004836	Anolis carolinensis	66.62	0.00e+00	914.00
IUUC-Ame-011946	Astyanax mexicanus	71.76	0.00e+00	995.00
IUUC-Bta-013131	Bos taurus	61.95	0.00e+00	742.00
IUUC-Cja-019599	Callithrix jacchus	68.19	0.00e+00	922.00
IUUC-Cfa-021003	Canis familiaris	66.76	0.00e+00	879.00
IUUC-Cpo-022143	Cavia porcellus	67.07	0.00e+00	899.00
IUUC-Csa-023477	Chlorocebus sabaeus	67.79	0.00e+00	906.00
IUUC-Cho-024734	Choloepus hoffmanni	50.29	4.00e-123	435.00
IUUC-Csv-025842	Ciona savignyi	60.73	8.00e-94	337.00
IUUC-Dre-027793	Danio rerio	73.53	0.00e+00	1063.00
IUUC-Dno-029253	Dasypus novemcinctus	66.89	0.00e+00	887.00
IUUC-Dor-030891	Dipodomys ordii	62.80	0.00e+00	828.00
IUUC-Dme-031796	Drosophila melanogaster	59.18	4.00e-95	342.00
IUUC-Ete-032646	Echinops telfairi	83.06	2.00e-117	416.00
IUUC-Eca-033805	Equus caballus	67.24	0.00e+00	891.00
IUUC-Eeu-035216	Erinaceus europaeus	65.87	1.00e-93	337.00
IUUC-Fca-035611	Felis catus	66.89	0.00e+00	850.00
IUUC-Fal-037186	Ficedula albicollis	65.60	0.00e+00	787.00
IUUC-Gmo-038824	Gadus morhua	81.40	0.00e+00	762.00
IUUC-Gga-040875	Gallus gallus	67.53	0.00e+00	907.00
IUUC-Gac-042226	Gasterosteus aculeatus	84.01	0.00e+00	1172.00
IUUC-Ggo-045122	Gorilla gorilla	66.49	0.00e+00	915.00
IUUC-Hsa-045882	Homo sapiens	67.16	0.00e+00	912.00
IUUC-Itr-048185	Ictidomys tridecemlineatus	67.79	0.00e+00	906.00
IUUC-Lch-049960	Latimeria chalumnae	64.40	0.00e+00	853.00
IUUC-Loc-052408	Lepisosteus oculatus	74.79	0.00e+00	646.00
IUUC-Laf-054187	Loxodonta africana	67.74	0.00e+00	912.00
IUUC-Mcc-055273	Macaca mulatta	66.71	0.00e+00	884.00
IUUC-Meu-056267	Macropus eugenii	65.00	0.00e+00	875.00
IUUC-Mga-059958	Meleagris gallopavo	82.15	1.00e-143	501.00
IUUC-Mmr-061280	Microcebus murinus	67.65	0.00e+00	899.00
IUUC-Mdo-062625	Monodelphis domestica	69.10	0.00e+00	951.00
IUUC-Mmu-063853	Mus musculus	67.20	0.00e+00	900.00
IUUC-Mlu-067771	Myotis lucifugus	68.15	0.00e+00	900.00
IUUC-Opr-070741	Ochotona princeps	68.06	0.00e+00	905.00
IUUC-Ont-072172	Oreochromis niloticus	85.66	0.00e+00	1251.00
IUUC-Oan-073167	Ornithorhynchus anatinus	63.35	0.00e+00	858.00
IUUC-Ocu-074176	Oryctolagus cuniculus	66.08	0.00e+00	880.00
IUUC-Ola-087203	Oryzias latipes	92.05	2.00e-145	508.00
IUUC-Oga-089153	Otolemur garnettii	66.89	0.00e+00	887.00
IUUC-Oar-090008	Ovis aries	66.13	0.00e+00	894.00
IUUC-Ptr-091234	Pan troglodytes	66.85	0.00e+00	912.00
IUUC-Pan-092005	Papio anubis	67.65	0.00e+00	912.00
IUUC-Psi-093995	Pelodiscus sinensis	74.87	2.00e-166	579.00
IUUC-Pma-094110	Petromyzon marinus	47.46	1.00e-117	416.00
IUUC-Pfo-097418	Poecilia formosa	82.24	0.00e+00	1160.00
IUUC-Pab-098267	Pongo abelii	66.85	0.00e+00	888.00
IUUC-Pca-101084	Procavia capensis	66.33	0.00e+00	855.00
IUUC-Pva-102292	Pteropus vampyrus	68.52	0.00e+00	636.00
IUUC-Rno-105251	Rattus norvegicus	66.01	0.00e+00	887.00
IUUC-Sha-107100	Sarcophilus harrisii	68.31	0.00e+00	931.00
IUUC-Sar-113559	Sorex araneus	61.73	1.00e-114	407.00
IUUC-Ssc-115688	Sus scrofa	68.20	0.00e+00	900.00
IUUC-Tgu-117424	Taeniopygia guttata	67.35	0.00e+00	909.00
IUUC-Tsy-119299	Tarsius syrichta	56.82	0.00e+00	628.00
IUUC-Tni-120808	Tetraodon nigroviridis	91.31	0.00e+00	1277.00
IUUC-Tbe-127705	Tupaia belangeri	73.33	5.00e-146	510.00
IUUC-Ttr-128225	Tursiops truncatus	66.22	0.00e+00	875.00
IUUC-Vpa-130193	Vicugna pacos	68.31	2.00e-89	323.00
IUUC-Xtr-132449	Xenopus tropicalis	65.32	0.00e+00	848.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence