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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018108
Ensembl Protein ID T14G8.1
UniProt Accession Q22516; Q18794; CHD3_CAEEL
Genbank Protein ID AAG29837.1; CAA91810.1; CAA91810.1
Protein Name Chromodomain-helicase-DNA-binding protein 3 homolog
Genbank Nucleotide ID AF308444; Z67884; Z67881
Gene Name chd-3; T14G8.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00000482 T14G8.1 T14G8.1
Annotation
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 activity/RING/PHD 1.50e-13 51.0 329 372
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 activity/RING/PHD
   S: 2    kvClvCgeggedekslveCekCrewfHpaClklsveeelpnsekwiCpkC 51
           ++C +C+e+++    ++ C+ C + +H+ C  ++  +e p+ e w Cp+C
   Q: 329  DYCRICKETSN----ILLCDTCPSSYHAYCIDPP-LTEIPEGE-WSCPRC 372
           69*******99....9******************.*******8.****** PP
   
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Chromatin-remodeling protein that has a role in notch signaling-dependent vulval cell fate determination. May also have a role in pharyngeal precursor cell specification.
 Chromatin-remodeling protein that has a role in notch signaling-dependent vulval cell fate determination. May also have a role in pharyngeal precursor cell specification.
Protein Sequence
(Fasta)
MSDDQHESID GDETMEEDSM LAEGHEDGEE DVGEDEEEVE TEESQGVPTT SEKKKPPPKK 60
KKGGKKSSKK KNNCDYPDPY KSTSAEISAA IGLTDVDVDY EQEEFQSITN LKNFSSLVKP 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018108|E3,PHD|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
TAATTCCCAT AAAGAACAAT GTCAGACGAT CAACACGAAT CAATCGACGG TGATGAGACA 60
ATGGAGGAGG ATTCCATGCT AGCAGAAGGT CATGAGGATG GAGAAGAAGA TGTCGGCGAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018108|E3,PHD|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0067--ATP-binding
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0238--DNA-binding
KW-0347--Helicase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR012957--CHD_C2
IPR012958--CHD_N
IPR000953--Chromo/chromo_shadow_dom
IPR023780--Chromo_domain
IPR016197--Chromodomain-like
IPR002464--DNA/RNA_helicase_DEAH_CS
IPR009462--DUF1086
IPR009463--DUF1087
IPR014001--Helicase_ATP-bd
IPR001650--Helicase_C
IPR027417--P-loop_NTPase
IPR000330--SNF2_N
IPR019786--Zinc_finger_PHD-type_CS
IPR011011--Znf_FYVE_PHD
IPR001965--Znf_PHD
IPR019787--Znf_PHD-finger
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD
PROSITE

PS50013--CHROMO_2
PS00690--DEAH_ATP_HELICASE
PS51192--HELICASE_ATP_BIND_1
PS51194--HELICASE_CTER
PS01359--ZF_PHD_1
PS50016--ZF_PHD_2
Pfam

PF08074--CHDCT2
PF08073--CHDNT
PF00385--Chromo
PF06461--DUF1086
PF06465--DUF1087
PF00271--Helicase_C
PF00628--PHD
PF00176--SNF2_N
SMART

SM00298--CHROMO
SM00487--DEXDc
SM01146--DUF1086
SM01147--DUF1087
SM00490--HELICc
SM00249--PHD
SM00184--RING
Gene Ontology

GO:0000118--C:histone deacetylase complex
GO:0005524--F:ATP binding
GO:0008026--F:ATP-dependent helicase activity
GO:0003682--F:chromatin binding
GO:0003677--F:DNA binding
GO:0003678--F:DNA helicase activity
GO:0008270--F:zinc ion binding
GO:0001709--P:cell fate determination
GO:0006338--P:chromatin remodeling
GO:0016569--P:covalent chromatin modification
GO:0046580--P:negative regulation of Ras protein signal transduction
GO:0040027--P:negative regulation of vulval development
GO:0006355--P:regulation of transcription, DNA-templated
KEGG cel:CELE_T14G8.1
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001361 Ailuropoda melanoleuca 56.46 0.00e+00 1292.00
IUUC-Aca-004671 Anolis carolinensis 57.42 0.00e+00 1288.00
IUUC-Ath-007406 Arabidopsis thaliana 40.53 7.00e-146 511.00
IUUC-Ame-011098 Astyanax mexicanus 58.12 0.00e+00 1280.00
IUUC-Bra-016724 Brassica rapa 40.48 9.00e-147 514.00
IUUC-Cja-019018 Callithrix jacchus 58.65 0.00e+00 1292.00
IUUC-Cpo-022083 Cavia porcellus 56.79 0.00e+00 1271.00
IUUC-Csa-023625 Chlorocebus sabaeus 57.68 0.00e+00 1301.00
IUUC-Cho-024361 Choloepus hoffmanni 60.09 0.00e+00 947.00
IUUC-Csv-025847 Ciona savignyi 46.92 0.00e+00 1183.00
IUUC-Dre-027505 Danio rerio 57.37 0.00e+00 1288.00
IUUC-Dor-030167 Dipodomys ordii 57.64 0.00e+00 1271.00
IUUC-Dme-032150 Drosophila melanogaster 52.96 0.00e+00 1238.00
IUUC-Ete-032757 Echinops telfairi 53.50 0.00e+00 1118.00
IUUC-Eeu-034777 Erinaceus europaeus 52.82 0.00e+00 1125.00
IUUC-Gmo-038957 Gadus morhua 60.16 0.00e+00 1060.00
IUUC-Gac-041375 Gasterosteus aculeatus 55.85 0.00e+00 1305.00
IUUC-Gma-043999 Glycine max 39.54 0.00e+00 699.00
IUUC-Ggo-044514 Gorilla gorilla 57.15 0.00e+00 1293.00
IUUC-Hsa-046181 Homo sapiens 57.15 0.00e+00 1294.00
IUUC-Lch-050343 Latimeria chalumnae 56.99 0.00e+00 1306.00
IUUC-Loc-052383 Lepisosteus oculatus 57.57 0.00e+00 1250.00
IUUC-Laf-053870 Loxodonta africana 58.13 0.00e+00 1281.00
IUUC-Mcc-055856 Macaca mulatta 57.15 0.00e+00 1294.00
IUUC-Meu-056292 Macropus eugenii 48.35 1.00e-151 530.00
IUUC-Mmr-060986 Microcebus murinus 56.90 0.00e+00 1284.00
IUUC-Mdo-062971 Monodelphis domestica 58.13 0.00e+00 1275.00
IUUC-Nle-069824 Nomascus leucogenys 57.28 0.00e+00 1297.00
IUUC-Opr-070960 Ochotona princeps 57.30 0.00e+00 1253.00
IUUC-Ont-072418 Oreochromis niloticus 56.74 0.00e+00 1277.00
IUUC-Oan-072885 Ornithorhynchus anatinus 55.03 0.00e+00 849.00
IUUC-Ola-086880 Oryzias latipes 56.91 0.00e+00 1304.00
IUUC-Oga-088775 Otolemur garnettii 56.81 0.00e+00 1287.00
IUUC-Oar-089784 Ovis aries 57.97 0.00e+00 1286.00
IUUC-Ptr-090586 Pan troglodytes 56.70 0.00e+00 1289.00
IUUC-Pan-092441 Papio anubis 57.68 0.00e+00 1302.00
IUUC-Psi-093007 Pelodiscus sinensis 55.69 0.00e+00 1276.00
IUUC-Ppa-095213 Physcomitrella patens 43.57 0.00e+00 637.00
IUUC-Pfo-097530 Poecilia formosa 56.14 0.00e+00 1292.00
IUUC-Pca-100559 Procavia capensis 52.47 0.00e+00 1136.00
IUUC-Pva-103186 Pteropus vampyrus 56.45 0.00e+00 1283.00
IUUC-Sha-107233 Sarcophilus harrisii 58.13 0.00e+00 1274.00
IUUC-Smo-108946 Selaginella moellendorffii 35.62 2.00e-160 560.00
IUUC-Sly-110976 Solanum lycopersicum 40.11 0.00e+00 708.00
IUUC-Ssc-116303 Sus scrofa 56.90 0.00e+00 1283.00
IUUC-Tgu-117484 Taeniopygia guttata 57.97 0.00e+00 1302.00
IUUC-Tru-118745 Takifugu rubripes 56.02 0.00e+00 1282.00
IUUC-Tsy-119261 Tarsius syrichta 61.45 0.00e+00 781.00
IUUC-Tni-120764 Tetraodon nigroviridis 57.18 0.00e+00 1273.00
IUUC-Tbe-128117 Tupaia belangeri 53.89 0.00e+00 691.00
IUUC-Ttr-128301 Tursiops truncatus 57.84 0.00e+00 1279.00
IUUC-Vpa-130209 Vicugna pacos 69.69 3.00e-126 445.00
IUUC-Vvi-130849 Vitis vinifera 41.02 0.00e+00 703.00
Created Date 25-Jun-2017

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