iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Meu-056155

Ensembl Protein ID

ENSMEUP00000011791.1

UniProt Accession

M1JPB0; M1JPB0_MACEU

Genbank Protein ID

AGE97655.1

Protein Name

Tyrosine-protein kinase

Genbank Nucleotide ID

KC153239

Gene Name

FGR; LynA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMEUG00000012926.1	ENSMEUT00000012965.1	ENSMEUP00000011791.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
UBD/SH3	3.30e-14	52.2	6	61

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

UBD/SH3

   S: 6    vqvlydyeaqnddeLtlkkGdvvlviekeeqdegWlkgvkelegkrGlfPenFvekle 63
           + +ly y+a ++d+Lt++kG++ +++  ++++++W+++ +  +g+ G +P n+v+ ++
   Q: 6    FVALYGYDARTEDDLTFTKGEKFHIL--NNTEGDWWEARSLSSGRTGYIPGNYVAPVN 61
           789***********************..8999**********************9997 PP

Organism

Macropus eugenii

Protein Sequence
(Fasta)

AGVTLFVALY GYDARTEDDL TFTKGEKFHI LNNTEGDWWE ARSLSSGRTG YIPGNYVAPV 60
NSIQAEEWYF GKTGRKDAER QLLSPSNPRG TFLVRESETT QGAYSLSIRD WDENKGDHVK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GCTGGAGTAA CTCTTTTCGT CGCCCTTTAT GGATATGATG CCAGGACTGA AGATGACCTC 60
ACCTTCACAA AAGGAGAAAA ATTCCACATC CTCAACAACA CGTGAGTGAC CCATGGGCCC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0067--ATP-binding
KW-0418--Kinase
KW-0547--Nucleotide-binding
KW-0728--SH3 domain
KW-0808--Transferase
KW-0829--Tyrosine-protein kinase

Interpro

IPR011009--Kinase-like_dom
IPR000719--Prot_kinase_dom
IPR017441--Protein_kinase_ATP_BS
IPR001245--Ser-Thr/Tyr_kinase_cat_dom
IPR000980--SH2
IPR001452--SH3_domain
IPR008266--Tyr_kinase_AS
IPR020635--Tyr_kinase_cat_dom

PROSITE

PS00107--PROTEIN_KINASE_ATP
PS50011--PROTEIN_KINASE_DOM
PS00109--PROTEIN_KINASE_TYR
PS50001--SH2
PS50002--SH3

Pfam

PF07714--Pkinase_Tyr
PF00017--SH2
PF00018--SH3_1

PRINTS

PR00401--SH2DOMAIN
PR00452--SH3DOMAIN
PR00109--TYRKINASE

SMART

SM00252--SH2
SM00326--SH3
SM00219--TyrKc

Gene Ontology

GO:0005524--F:ATP binding
GO:0004715--F:non-membrane spanning protein tyrosine kinase activity

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001938	Ailuropoda melanoleuca	82.74	0.00e+00	785.00
IUUC-Apl-003716	Anas platyrhynchos	77.01	0.00e+00	719.00
IUUC-Aca-004483	Anolis carolinensis	78.17	0.00e+00	726.00
IUUC-Ame-011876	Astyanax mexicanus	76.91	0.00e+00	719.00
IUUC-Bta-012607	Bos taurus	81.86	0.00e+00	775.00
IUUC-Cel-018682	Caenorhabditis elegans	54.14	2.00e-132	465.00
IUUC-Cja-018914	Callithrix jacchus	82.96	0.00e+00	785.00
IUUC-Cfa-020165	Canis familiaris	81.64	0.00e+00	769.00
IUUC-Cpo-021476	Cavia porcellus	81.74	0.00e+00	774.00
IUUC-Csa-023692	Chlorocebus sabaeus	82.52	0.00e+00	783.00
IUUC-Cho-025014	Choloepus hoffmanni	75.72	0.00e+00	704.00
IUUC-Cin-025390	Ciona intestinalis	65.35	4.00e-170	590.00
IUUC-Csv-026029	Ciona savignyi	66.59	9.00e-162	563.00
IUUC-Dre-027978	Danio rerio	76.58	0.00e+00	715.00
IUUC-Dno-028920	Dasypus novemcinctus	82.30	0.00e+00	775.00
IUUC-Dor-030202	Dipodomys ordii	75.11	0.00e+00	717.00
IUUC-Dme-031976	Drosophila melanogaster	59.34	7.00e-152	530.00
IUUC-Ete-033170	Echinops telfairi	69.74	0.00e+00	658.00
IUUC-Eca-033581	Equus caballus	83.63	0.00e+00	793.00
IUUC-Eeu-034950	Erinaceus europaeus	75.76	1.00e-122	432.00
IUUC-Fca-036499	Felis catus	83.44	0.00e+00	786.00
IUUC-Fal-036786	Ficedula albicollis	79.30	0.00e+00	735.00
IUUC-Gmo-038929	Gadus morhua	75.68	0.00e+00	706.00
IUUC-Gga-040762	Gallus gallus	78.85	0.00e+00	731.00
IUUC-Gac-042321	Gasterosteus aculeatus	75.39	0.00e+00	715.00
IUUC-Ggo-044640	Gorilla gorilla	82.30	0.00e+00	778.00
IUUC-Hsa-046751	Homo sapiens	82.30	0.00e+00	779.00
IUUC-Itr-048218	Ictidomys tridecemlineatus	82.96	0.00e+00	786.00
IUUC-Lch-050239	Latimeria chalumnae	76.27	0.00e+00	724.00
IUUC-Loc-052620	Lepisosteus oculatus	78.10	0.00e+00	726.00
IUUC-Laf-054128	Loxodonta africana	81.46	0.00e+00	776.00
IUUC-Mcc-054715	Macaca mulatta	82.52	0.00e+00	782.00
IUUC-Mga-059310	Meleagris gallopavo	76.05	0.00e+00	724.00
IUUC-Mmr-060615	Microcebus murinus	82.96	0.00e+00	789.00
IUUC-Mdo-062963	Monodelphis domestica	75.17	0.00e+00	716.00
IUUC-Mmu-063286	Mus musculus	79.91	0.00e+00	763.00
IUUC-Mpu-066641	Mustela putorius furo	82.52	0.00e+00	783.00
IUUC-Mlu-067315	Myotis lucifugus	75.72	0.00e+00	704.00
IUUC-Nle-068978	Nomascus leucogenys	76.91	0.00e+00	723.00
IUUC-Opr-070299	Ochotona princeps	67.41	0.00e+00	629.00
IUUC-Ont-072337	Oreochromis niloticus	75.83	0.00e+00	722.00
IUUC-Oan-073486	Ornithorhynchus anatinus	80.71	0.00e+00	766.00
IUUC-Ocu-074552	Oryctolagus cuniculus	83.71	0.00e+00	782.00
IUUC-Ola-086657	Oryzias latipes	77.75	0.00e+00	725.00
IUUC-Oga-088731	Otolemur garnettii	82.52	0.00e+00	784.00
IUUC-Oar-090207	Ovis aries	82.74	0.00e+00	782.00
IUUC-Ptr-090979	Pan troglodytes	82.30	0.00e+00	778.00
IUUC-Pan-092188	Papio anubis	82.52	0.00e+00	783.00
IUUC-Psi-093310	Pelodiscus sinensis	76.50	0.00e+00	729.00
IUUC-Pma-094232	Petromyzon marinus	76.69	0.00e+00	735.00
IUUC-Pfo-096519	Poecilia formosa	80.49	0.00e+00	760.00
IUUC-Pab-098617	Pongo abelii	82.08	0.00e+00	779.00
IUUC-Pca-100245	Procavia capensis	75.88	0.00e+00	709.00
IUUC-Pva-102645	Pteropus vampyrus	75.50	0.00e+00	704.00
IUUC-Rno-104945	Rattus norvegicus	80.57	0.00e+00	767.00
IUUC-Sha-107103	Sarcophilus harrisii	90.27	0.00e+00	855.00
IUUC-Sar-113364	Sorex araneus	71.40	0.00e+00	674.00
IUUC-Ssc-116389	Sus scrofa	75.88	0.00e+00	709.00
IUUC-Tgu-117206	Taeniopygia guttata	77.35	0.00e+00	724.00
IUUC-Tru-117594	Takifugu rubripes	76.05	0.00e+00	721.00
IUUC-Tni-120886	Tetraodon nigroviridis	77.75	0.00e+00	725.00
IUUC-Tbe-127707	Tupaia belangeri	75.33	0.00e+00	696.00
IUUC-Ttr-128893	Tursiops truncatus	74.94	0.00e+00	715.00
IUUC-Vpa-130060	Vicugna pacos	75.17	0.00e+00	716.00
IUUC-Xtr-132957	Xenopus tropicalis	77.83	0.00e+00	751.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence