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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106254
UUCD1 version UUC-SaC-00113
Ensembl Protein ID YBR281C
UniProt Accession P38149; D6VQS6; DUG2_YEAST
Genbank Protein ID CAA53644.1; CAA85245.1; DAA07396.1
Protein Name Probable di- and tripeptidase DUG2; Deficient in utilization of glutathione protein 2; GSH degradosomal complex subunit DUG2
Genbank Nucleotide ID X76053; Z36150; BK006936
Gene Name DUG2; YBR281C; YBR2018
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YBR281C YBR281C YBR281C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
CPLMdbPAFdbPTMBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.70e-16 57.5 295 318
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 9    lafsdtllvsGsdDgtikvWDlrtgv 34
           ++f  ++l +G  Dg ik+WDl t+ 
   Q: 295  IEF--PFLYCGLTDGIIKIWDLNTQQ 318
           677..79**************99876 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond.
 Component of the GSH degradosomal complex involved in the degradation of glutathione (GSH) and other peptides containing a gamma-glu-X bond.
Protein Sequence
(Fasta)
MYDSRGVALH SELIHRWNHA FSILSIVAFP KKRLLFAGSQ DSKILVFDLP TYNLIHTIRL 60
GESQEETHTR SSVLCLTGSE DENFLFSGGA DSLVRIWSIG EKTIRDDFLP VTEIATVYSV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106254|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTACGATA GCAGGGGTGT CGCATTGCAC TCTGAACTAA TTCATAGGTG GAATCACGCT 60
TTTTCCATCT TATCCATTGT TGCATTTCCA AAAAAAAGAT TGTTGTTTGC TGGTAGCCAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106254|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0224--Dipeptidase
KW-0378--Hydrolase
KW-0479--Metal-binding
KW-0482--Metalloprotease
KW-0539--Nucleus
KW-0645--Protease
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
KW-0862--Zinc
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR017149--GSH_degradosome_DUG2
IPR002933--Peptidase_M20
IPR011650--Peptidase_M20_dimer
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF07687--M20_dimer
PF01546--Peptidase_M20
PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0061672--C:glutathione hydrolase complex
GO:0034399--C:nuclear periphery
GO:0016805--F:dipeptidase activity
GO:0046872--F:metal ion binding
GO:0008237--F:metallopeptidase activity
GO:0008242--F:omega peptidase activity
GO:0008233--F:peptidase activity
GO:0006751--P:glutathione catabolic process
KEGG sce:YBR281C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ago-007956 Ashbya gossypii 51.83 0.00e+00 896.00
IUUC-Acl-008006 Aspergillus clavatus 32.97 1.00e-111 395.00
IUUC-Afl-008619 Aspergillus flavus 31.29 3.00e-102 364.00
IUUC-Afu-009116 Aspergillus fumigatus 32.48 2.00e-112 398.00
IUUC-Ani-009184 Aspergillus nidulans 32.15 1.00e-103 369.00
IUUC-Ang-009849 Aspergillus niger 31.47 4.00e-95 340.00
IUUC-Aor-010088 Aspergillus oryzae 31.58 8.00e-118 416.00
IUUC-Ate-010369 Aspergillus terreus 32.20 2.00e-112 398.00
IUUC-Bgr-012070 Blumeria graminis 33.73 1.00e-112 399.00
IUUC-Bci-013989 Botrytis cinerea 31.97 1.00e-120 425.00
IUUC-Cgl-026547 Colletotrichum gloeosporioides 33.69 2.00e-132 464.00
IUUC-Cne-026813 Cryptococcus neoformans 31.34 2.00e-109 388.00
IUUC-Cme-027264 Cyanidioschyzon merolae 26.87 4.00e-38 152.00
IUUC-Dse-031431 Dothistroma septosporum 32.65 7.00e-118 416.00
IUUC-Fox-037806 Fusarium oxysporum 31.57 1.00e-120 425.00
IUUC-Fso-038250 Fusarium solani 32.73 6.00e-126 442.00
IUUC-Ggr-039782 Gaeumannomyces graminis 31.25 8.00e-115 405.00
IUUC-Kpa-049302 Komagataella pastoris 40.66 0.00e+00 631.00
IUUC-Lma-053087 Leptosphaeria maculans 32.22 1.00e-131 462.00
IUUC-Mor-057089 Magnaporthe oryzae 31.49 8.00e-135 472.00
IUUC-Mpo-057545 Magnaporthe poae 31.56 2.00e-111 395.00
IUUC-Mla-059181 Melampsora laricipopulina 32.75 2.00e-107 382.00
IUUC-Mvi-060505 Microbotryum violaceum 29.72 1.00e-98 352.00
IUUC-Nfi-068381 Neosartorya fischeri 32.23 4.00e-112 397.00
IUUC-Ncr-068684 Neurospora crassa 31.80 6.00e-100 356.00
IUUC-Pno-094934 Phaeosphaeria nodorum 33.50 2.00e-120 424.00
IUUC-Pgr-103367 Puccinia graminis 31.89 8.00e-106 376.00
IUUC-Pte-104056 Pyrenophora teres 34.50 2.00e-122 431.00
IUUC-Pyt-104783 Pyrenophora triticirepentis 34.44 4.00e-115 407.00
IUUC-Ssl-108564 Sclerotinia sclerotiorum 31.81 3.00e-124 437.00
IUUC-Sre-115152 Sporisorium reilianum 41.82 6.00e-87 313.00
IUUC-Tre-122000 Trichoderma reesei 31.53 2.00e-119 421.00
IUUC-Tvi-122379 Trichoderma virens 32.00 1.00e-125 442.00
IUUC-Tme-127022 Tuber melanosporum 36.34 8.00e-151 525.00
IUUC-Uma-129519 Ustilago maydis 40.00 3.00e-85 308.00
IUUC-Vda-129987 Verticillium dahliae 32.49 1.00e-126 445.00
IUUC-Yli-134574 Yarrowia lipolytica 38.27 8.00e-161 558.00
Created Date 25-Jun-2017

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