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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Rno-105155
Ensembl Protein ID ENSRNOP00000027553.4
UniProt Accession Q5I0C9; Q5I0C9_RAT
Genbank Protein ID AAH88461.1
Protein Name Cirrhosis, autosomal recessive 1A (Human); UTP4 small subunit processome component
Genbank Nucleotide ID AC116255
Gene Name Utp4; Cirh1a
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSRNOG00000020333.6 ENSRNOT00000027553.6 ENSRNOP00000027553.4
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
microRNATRANSFACRAID2
Protein-protein Interaction
IID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.70e-14 53.1 196 231
UBD/Beta-Prp 5.90e-40 137.7 17 263
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 4    dsvtclaf.sdtllvsGsdDgtikvWDlrtgvllks 38
           + v+++af sd++++s    g++++WD  tg+l+ks
   Q: 196  CIVWGVAFlSDGTVISVDSVGKVQLWDSATGTLVKS 231
           56899999*99888999999**********999875 PP
   

   UBD/Beta-Prp
   S: 11   svitcvkfspdksllatgsrdgtikvwdvttgkllrsl.sghea.evtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsv 97
           s i+cv++ ++++ la++ +dgt+++++++   + +++  ghe+ ++ a+++ + +  l +++  + i  +dl++  + +tl +    +
   Q: 17   SGIRCVAYNNQSNRLAVSRTDGTVEIYNLSANYFQEKFfPGHESrGTEALCWAEGQ-RLFSAGLNGEILEYDLQALNIKYTLDAFGGPI 104
           5689******************************9999988865279999999998.77777777777779****************** PP
   S: 98   lslsfspsgdklvsGshdrtirvwdletgqclee.tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtl...tgghtds 182
           +s++ spsg+ l++G +d  ++++++  ++   +  ++ +++ + ++++hp g  +++Gs D  + ++d+k+g++ r++   +  ++  
   Q: 105  WSMTASPSGSQLLVGCEDGSVKLFEVTPDKIQFArNFDRQKSRILSLSWHPAGTHVAAGSIDY-ISVFDVKSGSITRKMvldR--QHLG 190
           **************************9888765559999999********************7.8**************9752..4444 PP
   S: 183  vysls.......fdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriW 249
           v++         f s+g  ++s++  g+v+lwd  tg+ v++    ++ v+s+++ ++++ +v+g+++g+++ +
   Q: 191  VTKSRcivwgvaFLSDG-TVISVDSVGKVQLWDSATGTLVKSHLIANADVQSIAVADQEDSFVVGTAEGTVFHF 263
           44444455666788887.9****************************************************977 PP
   
Organism Rattus norvegicus
Protein Sequence
(Fasta)
MGEFKVHRVR FFNYVPSGIR CVAYNNQSNR LAVSRTDGTV EIYNLSANYF QEKFFPGHES 60
RGTEALCWAE GQRLFSAGLN GEILEYDLQA LNIKYTLDAF GGPIWSMTAS PSGSQLLVGC 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Rno-105155|E3,WD_repeat;UBD,Beta-Prp|Rattus norvegicus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGGGACGGAG CTATAGAGTG CGCACGCGCG CACGTGGGAC CGGGGCGGAG AGAGGCGAGG 60
TCCCGGGTAG CGAGTGCCTG GCGGTAGGTG AGTTCGGGGA GAATCCCCGG GGGTAGCTGA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Rno-105155|E3,WD_repeat;UBD,Beta-Prp|Rattus norvegicus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005694--C:chromosome
GO:0001650--C:fibrillar center
GO:0005730--C:nucleolus
GO:0034455--C:t-UTP complex
GO:0003723--F:RNA binding
GO:0030490--P:maturation of SSU-rRNA
GO:0006355--P:regulation of transcription, DNA-templated
KEGG rno:291987
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001161 Aegilops tauschii 25.35 8.00e-46 178.00
IUUC-Aml-001310 Ailuropoda melanoleuca 91.55 0.00e+00 1334.00
IUUC-Atr-003076 Amborella trichopoda 23.49 8.00e-35 142.00
IUUC-Apl-003367 Anas platyrhynchos 57.14 3.00e-55 207.00
IUUC-Aca-004429 Anolis carolinensis 60.05 3.00e-142 497.00
IUUC-Aly-006271 Arabidopsis lyrata 23.22 9.00e-41 162.00
IUUC-Ath-007331 Arabidopsis thaliana 24.34 2.00e-38 154.00
IUUC-Ago-007843 Ashbya gossypii 25.16 9.00e-40 158.00
IUUC-Acl-008229 Aspergillus clavatus 25.88 2.00e-39 158.00
IUUC-Afl-008438 Aspergillus flavus 26.57 2.00e-39 157.00
IUUC-Afu-008910 Aspergillus fumigatus 25.14 7.00e-36 146.00
IUUC-Ani-009321 Aspergillus nidulans 29.51 3.00e-39 157.00
IUUC-Ang-009592 Aspergillus niger 26.59 2.00e-41 164.00
IUUC-Aor-010220 Aspergillus oryzae 26.27 2.00e-39 157.00
IUUC-Ate-010317 Aspergillus terreus 26.84 1.00e-38 155.00
IUUC-Ame-010957 Astyanax mexicanus 53.78 0.00e+00 772.00
IUUC-Bgr-012057 Blumeria graminis 26.74 2.00e-37 150.00
IUUC-Bta-012473 Bos taurus 88.21 0.00e+00 1286.00
IUUC-Bdi-014203 Brachypodium distachyon 23.47 2.00e-39 157.00
IUUC-Bol-016163 Brassica oleracea 24.64 2.00e-47 184.00
IUUC-Bra-017482 Brassica rapa 23.77 2.00e-46 181.00
IUUC-Cja-019942 Callithrix jacchus 89.80 0.00e+00 1312.00
IUUC-Cfa-020549 Canis familiaris 91.49 0.00e+00 934.00
IUUC-Cpo-022088 Cavia porcellus 91.84 0.00e+00 1315.00
IUUC-Csa-023773 Chlorocebus sabaeus 90.96 0.00e+00 1325.00
IUUC-Cho-024302 Choloepus hoffmanni 87.87 0.00e+00 1047.00
IUUC-Cin-025384 Ciona intestinalis 33.33 4.00e-114 405.00
IUUC-Dre-027460 Danio rerio 53.42 0.00e+00 765.00
IUUC-Dno-029594 Dasypus novemcinctus 89.22 0.00e+00 1261.00
IUUC-Dor-030564 Dipodomys ordii 87.95 0.00e+00 805.00
IUUC-Dse-031179 Dothistroma septosporum 25.76 4.00e-35 143.00
IUUC-Dme-031603 Drosophila melanogaster 24.36 9.00e-57 214.00
IUUC-Ete-032655 Echinops telfairi 82.65 0.00e+00 1189.00
IUUC-Eca-033838 Equus caballus 91.11 0.00e+00 1327.00
IUUC-Eeu-034548 Erinaceus europaeus 87.03 0.00e+00 1262.00
IUUC-Fca-035715 Felis catus 91.11 0.00e+00 1328.00
IUUC-Fal-037394 Ficedula albicollis 57.21 0.00e+00 755.00
IUUC-Gmo-039235 Gadus morhua 47.81 0.00e+00 680.00
IUUC-Ggr-040043 Gaeumannomyces graminis 26.21 1.00e-31 132.00
IUUC-Gga-041172 Gallus gallus 60.32 0.00e+00 870.00
IUUC-Gac-042466 Gasterosteus aculeatus 53.56 0.00e+00 764.00
IUUC-Gma-044222 Glycine max 25.04 1.00e-41 165.00
IUUC-Ggo-045416 Gorilla gorilla 87.76 0.00e+00 1265.00
IUUC-Hsa-046115 Homo sapiens 90.99 0.00e+00 1290.00
IUUC-Hvu-047229 Hordeum vulgare 24.39 4.00e-43 169.00
IUUC-Itr-048015 Ictidomys tridecemlineatus 91.25 0.00e+00 1330.00
IUUC-Kpa-049370 Komagataella pastoris 20.67 4.00e-30 126.00
IUUC-Lch-050153 Latimeria chalumnae 58.08 0.00e+00 828.00
IUUC-Lpe-051220 Leersia perrieri 24.15 7.00e-45 175.00
IUUC-Loc-052617 Lepisosteus oculatus 54.03 0.00e+00 795.00
IUUC-Laf-053613 Loxodonta africana 88.78 0.00e+00 1287.00
IUUC-Mcc-055707 Macaca mulatta 90.57 0.00e+00 1286.00
IUUC-Meu-056800 Macropus eugenii 66.61 0.00e+00 793.00
IUUC-Mor-057245 Magnaporthe oryzae 26.72 6.00e-29 122.00
IUUC-Mpo-057446 Magnaporthe poae 26.26 7.00e-31 129.00
IUUC-Mtr-058748 Medicago truncatula 23.70 1.00e-42 168.00
IUUC-Mga-060018 Meleagris gallopavo 59.85 0.00e+00 839.00
IUUC-Mmr-061115 Microcebus murinus 90.52 0.00e+00 1297.00
IUUC-Mdo-062235 Monodelphis domestica 76.38 0.00e+00 1129.00
IUUC-Mmu-063158 Mus musculus 97.23 0.00e+00 1399.00
IUUC-Mac-065380 Musa acuminata 24.73 6.00e-53 202.00
IUUC-Mpu-065805 Mustela putorius furo 90.96 0.00e+00 1328.00
IUUC-Mlu-066951 Myotis lucifugus 89.21 0.00e+00 1298.00
IUUC-Nfi-068295 Neosartorya fischeri 25.78 3.00e-37 150.00
IUUC-Ncr-068880 Neurospora crassa 26.03 8.00e-37 149.00
IUUC-Nle-069657 Nomascus leucogenys 91.40 0.00e+00 1336.00
IUUC-Opr-070250 Ochotona princeps 88.63 0.00e+00 1278.00
IUUC-Ont-072642 Oreochromis niloticus 51.82 0.00e+00 727.00
IUUC-Ocu-074741 Oryctolagus cuniculus 90.09 0.00e+00 1312.00
IUUC-Oba-074974 Oryza barthii 23.69 5.00e-45 176.00
IUUC-Obr-076586 Oryza brachyantha 25.27 6.00e-42 165.00
IUUC-Ogl-077782 Oryza glaberrima 24.15 2.00e-47 184.00
IUUC-Ogu-078333 Oryza glumaepatula 24.45 5.00e-43 169.00
IUUC-Oin-079852 Oryza indica 24.27 1.00e-48 188.00
IUUC-Olo-080370 Oryza longistaminata 26.57 5.00e-39 155.00
IUUC-Ome-081442 Oryza meridionalis 24.07 6.00e-48 186.00
IUUC-Oni-082341 Oryza nivara 24.45 3.00e-43 170.00
IUUC-Opu-083824 Oryza punctata 23.82 4.00e-46 179.00
IUUC-Oru-084827 Oryza rufipogon 24.02 1.00e-46 181.00
IUUC-Osa-085742 Oryza sativa 24.18 4.00e-49 189.00
IUUC-Ola-086466 Oryzias latipes 53.54 0.00e+00 744.00
IUUC-Olu-087761 Ostreococcus lucimarinus 24.85 3.00e-51 196.00
IUUC-Oga-088721 Otolemur garnettii 83.50 0.00e+00 1168.00
IUUC-Oar-089532 Ovis aries 89.07 0.00e+00 1300.00
IUUC-Ptr-091604 Pan troglodytes 91.11 0.00e+00 1329.00
IUUC-Pan-092060 Papio anubis 93.30 0.00e+00 766.00
IUUC-Psi-093070 Pelodiscus sinensis 60.79 0.00e+00 853.00
IUUC-Pma-094201 Petromyzon marinus 49.38 1.00e-139 489.00
IUUC-Ppa-095599 Physcomitrella patens 28.06 2.00e-32 134.00
IUUC-Pfo-097207 Poecilia formosa 51.09 0.00e+00 717.00
IUUC-Pab-097746 Pongo abelii 91.11 0.00e+00 1327.00
IUUC-Pop-099669 Populus trichocarpa 24.24 3.00e-52 200.00
IUUC-Pca-100562 Procavia capensis 80.29 0.00e+00 915.00
IUUC-Ppe-101747 Prunus persica 23.33 1.00e-48 187.00
IUUC-Pva-103054 Pteropus vampyrus 90.38 0.00e+00 1321.00
IUUC-Pte-104064 Pyrenophora teres 25.55 5.00e-29 123.00
IUUC-Pyt-104595 Pyrenophora triticirepentis 26.08 4.00e-31 130.00
IUUC-Sce-106369 Saccharomyces cerevisiae 23.36 1.00e-42 168.00
IUUC-Sha-107149 Sarcophilus harrisii 75.80 0.00e+00 1126.00
IUUC-Sja-107777 Schizosaccharomyces japonicus 28.30 3.00e-65 243.00
IUUC-Spo-108372 Schizosaccharomyces pombe 28.57 3.00e-69 256.00
IUUC-Ssl-108650 Sclerotinia sclerotiorum 27.52 2.00e-42 167.00
IUUC-Smo-108851 Selaginella moellendorffii 24.03 2.00e-53 204.00
IUUC-Sit-110454 Setaria italica 25.00 4.00e-42 166.00
IUUC-Sly-111875 Solanum lycopersicum 24.52 2.00e-49 191.00
IUUC-Stu-112275 Solanum tuberosum 23.46 1.00e-43 171.00
IUUC-Sar-113254 Sorex araneus 77.27 0.00e+00 687.00
IUUC-Sbi-114624 Sorghum bicolor 24.73 4.00e-41 162.00
IUUC-Sre-114985 Sporisorium reilianum 20.06 2.00e-16 81.60
IUUC-Tgu-117407 Taeniopygia guttata 58.60 6.00e-144 503.00
IUUC-Tru-118733 Takifugu rubripes 47.74 0.00e+00 685.00
IUUC-Tsy-119213 Tarsius syrichta 79.94 0.00e+00 1023.00
IUUC-Tni-120894 Tetraodon nigroviridis 48.50 1.00e-98 352.00
IUUC-Tca-121606 Theobroma cacao 23.90 1.00e-43 171.00
IUUC-Tre-121958 Trichoderma reesei 27.00 9.00e-38 152.00
IUUC-Tvi-122290 Trichoderma virens 26.71 1.00e-38 154.00
IUUC-Tae-125538 Triticum aestivum 25.04 2.00e-45 177.00
IUUC-Tme-126995 Tuber melanosporum 25.71 2.00e-32 134.00
IUUC-Tbe-127605 Tupaia belangeri 74.29 5.00e-69 255.00
IUUC-Ttr-128720 Tursiops truncatus 88.92 0.00e+00 1288.00
IUUC-Uma-129564 Ustilago maydis 20.84 2.00e-15 78.20
IUUC-Vpa-130412 Vicugna pacos 89.43 3.00e-134 472.00
IUUC-Vvi-131256 Vitis vinifera 25.36 7.00e-49 189.00
IUUC-Xtr-131828 Xenopus tropicalis 55.94 0.00e+00 804.00
IUUC-Xma-133394 Xiphophorus maculatus 52.17 0.00e+00 729.00
IUUC-Yli-134565 Yarrowia lipolytica 28.35 1.00e-34 141.00
Created Date 25-Jun-2017

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