iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
FBgn0264442	FBtr0332557	FBpp0304815
FBgn0264442	FBtr0332558	FBpp0304816
FBgn0264442	FBtr0332561	FBpp0304819

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
miRTarBase	microRNA	TRANSFAC	miRecords
RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Post-translational Modifications (PTMs)
dbPAF	dbPTM	Phospho.ELM	UniProt
Protein Expression/Proteomics

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/BCR/BTB_Other: BTB	2.80e-11	43.6	104	166

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/BCR/BTB_Other: BTB

   S: 2    DvilvvggeeffahkivLaasSsvFyalflmeleesksklmveikdvqpevfrallkFlYtgklde 67
           Dv+l ++++ f ahk+vL+a+S++F++l++ +  e   ++ v ++dv ++ ++ ll+F+Y g+++ 
   Q: 104  DVTLACDERSFTAHKVVLSACSPYFRRLLKANPCE---HPIVILRDVRCDDVENLLSFMYNGEVNV 166
           9****************************999999...5899999*****************9975 PP

Organism

Drosophila melanogaster

Functional Description
(View)

Expression is vital for development; may be involved in transcriptional regulation. In embryos, muscle specific expression is required for segmental nerve b (SNb) motoneuron target recognition within ventral longitudinal muscles. Has a role in establishing and maintaining embryonic muscle attachments, adult sensory cell formation (macrochaetae) and morphogenesis of adult appendages (legs, antenna aristae and male external genitalia). Has a role in the morphogenesis of the class I dendritic neurons: selective expression of ab in class I da neurons plays a pivotal role in forming dendritic arbors, which are characteristic of the class I cells. The development of more complex arbors of class II-IV neurons depends on the absence of ab.

Protein Sequence
(Fasta)

MTESTQLQTA ENNNAGVVKM EPPPPATSSV SVSAAAAAHA LSSLSSLTMA ATGSALSPAT 60
PPPSLNLSHQ QQQHQQHYAL KWNDFQSSIL SSFRHLRDEE DFVDVTLACD ERSFTAHKVV 120

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Nucleotide Sequence
(Fasta)

CGCAGTACAA TTTCAGAAAT CAGACGGGCA GCAAGTGTCG TGGTTCAAGT GCGGCTAATT 60
TGGCTTATAT GTGATTTTCA GTGTTTTGAT GGCTTAGTAA ACTATCAGAA ACACAGAGAC 120

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Sequence Source

Ensembl

Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0217--Developmental protein
KW-0238--DNA-binding
KW-0479--Metal-binding
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR000210--BTB/POZ_dom
IPR011333--SKP1/BTB/POZ
IPR013087--Znf_C2H2_type

PROSITE

PS50097--BTB
PS00028--ZINC_FINGER_C2H2_1
PS50157--ZINC_FINGER_C2H2_2

Pfam

PF00651--BTB

SMART

SM00225--BTB
SM00355--ZnF_C2H2

Gene Ontology

GO:0005634--C:nucleus
GO:0003677--F:DNA binding
GO:0046872--F:metal ion binding
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0016198--P:axon choice point recognition
GO:0007298--P:border follicle cell migration
GO:0048813--P:dendrite morphogenesis
GO:0016203--P:muscle attachment
GO:0007517--P:muscle organ development
GO:0016319--P:mushroom body development
GO:0000122--P:negative regulation of transcription from RNA polymerase II promoter
GO:0048666--P:neuron development
GO:0044719--P:regulation of imaginal disc-derived wing size
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007423--P:sensory organ development
GO:0008039--P:synaptic target recognition
GO:0006351--P:transcription, DNA-templated

KEGG

dme:Dmel_CG43860

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Mpo-057526	Magnaporthe poae	33.72	6.00e-09	53.10

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence