iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	7.50e-25	86.0	250	282
UBD/Beta-Prp	2.90e-62	210.5	40	318

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf.sd.tllvsGsdDgtikvWDlrt 32
           H   vtcl++ sd ++l+sG+ D  +k++D++t
   Q: 250  HHKTVTCLRLgSDgRRLLSGGLDRHVKIYDVST 282
           7778*******999****************987 PP

UBD/Beta-Prp

   S: 9    hksvitcvkf..spdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfsp 104
           +   i  ++f  s+ +++++t + + +++++++ t+ +++ ls  +++ +  +f +dg +l+ g e +++k++d  ++ +++ +kgh++ v  + f +
   Q: 40   N--TIDYLDFspSDPDNFVVT-C-SVRVQIYNLVTMLVVKNLSRFQKTAYGATFRQDGRLLAAGDEEGHVKLFDTTSRNILRLFKGHTAPVHRTFFTA 133
           3..477889943344454444.4.69************************************************************************ PP
   S: 105  sgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsld 201
           ++  l+s ++d+ +r+wd+ +++++++ ++ h++ v+  ++hp++  ++vsG++D++++l+d + ++ +++    h  +v+s+ f +ng  +vs++  
   Q: 134  DKLQLASFGDDKSVRLWDVANEKVVQTYEDTHTDYVRAGAMHPQAgHMFVSGGYDGKIKLYDTRAETAVQRTLD-HGAPVESMLFLPNGSIFVSAG-G 229
           **********************************************************************9998.**************9999976.6 PP
   S: 202  gtvklwdlqtgec.vrtlnghtdnvksvrfspnderlvsgssDgsiriWdlrsgdllktlqlhnssvisvavlsfgdnvlvlgsedskvni 291
           ++v++wdl +g   +  +  h ++v+++r+ +++ rl+sg+ D+ ++i+d+ + ++++tl+++n  v+s+av   gd+ +v+g  d+ v i
   Q: 230  SQVRVWDLISGCRlLTMMSQHHKTVTCLRLGSDGRRLLSGGLDRHVKIYDVSTYKTVHTLTYPN-AVVSMAV-ADGDQAVVAGMVDGLVSI 318
           89*******99553666778******************************************99.7777777.456777777777888877 PP

Organism

Drosophila melanogaster

Protein Sequence
(Fasta)

MQNSFLPLNT RRFRQRAQVE TPDTVYWDRL AKPELLKEHN TIDYLDFSPS DPDNFVVTCS 60
VRVQIYNLVT MLVVKNLSRF QKTAYGATFR QDGRLLAAGD EEGHVKLFDT TSRNILRLFK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ACTCTTCCCA TCTAACACGT GCGCGCCCGA AAGAGATTTA GTAGAAATAC ACAGACAGGA 60
TGCAGAACTC CTTTCTTCCA CTGAACACAC GGCGTTTTCG ACAGCGGGCC CAGGTGGAAA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR018983--U3_snoRNA-assocProt_15_C
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF09384--UTP15_C
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005730--C:nucleolus
GO:0034455--C:t-UTP complex
GO:0030515--F:snoRNA binding
GO:0009267--P:cellular response to starvation
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0045943--P:positive regulation of transcription from RNA polymerase I promoter

KEGG

dme:Dmel_CG3071

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002117	Ailuropoda melanoleuca	39.38	5.00e-94	337.00
IUUC-Atr-003068	Amborella trichopoda	27.89	1.00e-55	209.00
IUUC-Apl-003926	Anas platyrhynchos	39.30	6.00e-95	340.00
IUUC-Aca-004271	Anolis carolinensis	38.31	4.00e-89	321.00
IUUC-Aly-005525	Arabidopsis lyrata	30.30	8.00e-53	200.00
IUUC-Ath-006954	Arabidopsis thaliana	29.49	6.00e-51	194.00
IUUC-Ago-007973	Ashbya gossypii	31.82	6.00e-63	234.00
IUUC-Acl-008287	Aspergillus clavatus	30.42	2.00e-48	185.00
IUUC-Afl-008504	Aspergillus flavus	32.22	6.00e-61	227.00
IUUC-Afu-008983	Aspergillus fumigatus	31.88	8.00e-45	174.00
IUUC-Ani-009315	Aspergillus nidulans	31.25	3.00e-51	195.00
IUUC-Ang-009690	Aspergillus niger	30.83	7.00e-58	217.00
IUUC-Aor-010181	Aspergillus oryzae	32.22	6.00e-61	227.00
IUUC-Ate-010498	Aspergillus terreus	31.47	6.00e-57	214.00
IUUC-Ame-011814	Astyanax mexicanus	38.90	7.00e-94	337.00
IUUC-Bgr-012273	Blumeria graminis	30.41	1.00e-62	233.00
IUUC-Bta-013068	Bos taurus	38.38	1.00e-93	336.00
IUUC-Bci-013930	Botrytis cinerea	30.06	9.00e-62	230.00
IUUC-Bdi-014876	Brachypodium distachyon	29.04	1.00e-53	203.00
IUUC-Bol-015366	Brassica oleracea	29.75	6.00e-52	197.00
IUUC-Bra-017589	Brassica rapa	29.49	9.00e-52	197.00
IUUC-Cel-018159	Caenorhabditis elegans	26.75	1.00e-53	203.00
IUUC-Cja-019139	Callithrix jacchus	39.20	3.00e-92	331.00
IUUC-Cfa-020742	Canis familiaris	38.20	9.00e-91	326.00
IUUC-Cpo-021707	Cavia porcellus	39.07	4.00e-94	337.00
IUUC-Cre-022665	Chlamydomonas reinhardtii	34.75	1.00e-66	246.00
IUUC-Csa-023024	Chlorocebus sabaeus	39.67	2.00e-94	338.00
IUUC-Cho-024487	Choloepus hoffmanni	45.22	9.00e-62	230.00
IUUC-Cin-025294	Ciona intestinalis	38.93	1.00e-104	372.00
IUUC-Cgl-026388	Colletotrichum gloeosporioides	29.36	4.00e-39	154.00
IUUC-Cne-026945	Cryptococcus neoformans	34.56	2.00e-67	248.00
IUUC-Cme-027108	Cyanidioschyzon merolae	29.61	1.00e-53	203.00
IUUC-Dre-028316	Danio rerio	38.51	2.00e-95	342.00
IUUC-Dno-028985	Dasypus novemcinctus	39.04	6.00e-92	330.00
IUUC-Dor-030219	Dipodomys ordii	31.33	2.00e-44	172.00
IUUC-Dse-031495	Dothistroma septosporum	30.11	1.00e-42	167.00
IUUC-Ete-032630	Echinops telfairi	49.08	2.00e-68	252.00
IUUC-Eca-033816	Equus caballus	39.67	1.00e-93	335.00
IUUC-Eeu-034840	Erinaceus europaeus	49.03	4.00e-63	234.00
IUUC-Fca-035751	Felis catus	39.87	2.00e-95	342.00
IUUC-Fal-036733	Ficedula albicollis	38.08	2.00e-99	355.00
IUUC-Fox-037743	Fusarium oxysporum	29.44	1.00e-57	216.00
IUUC-Fso-038395	Fusarium solani	28.79	3.00e-56	211.00
IUUC-Gmo-038803	Gadus morhua	38.14	5.00e-90	323.00
IUUC-Ggr-040092	Gaeumannomyces graminis	37.06	1.00e-44	173.00
IUUC-Gga-040714	Gallus gallus	39.42	1.00e-97	349.00
IUUC-Gac-042640	Gasterosteus aculeatus	38.48	9.00e-99	353.00
IUUC-Gma-044192	Glycine max	31.14	2.00e-52	199.00
IUUC-Ggo-045616	Gorilla gorilla	37.08	4.00e-90	324.00
IUUC-Hsa-046720	Homo sapiens	38.67	1.00e-90	326.00
IUUC-Itr-048796	Ictidomys tridecemlineatus	39.25	3.00e-91	328.00
IUUC-Kpa-049291	Komagataella pastoris	30.80	1.00e-60	226.00
IUUC-Lch-049729	Latimeria chalumnae	39.28	3.00e-84	305.00
IUUC-Lpe-051141	Leersia perrieri	28.27	3.00e-50	192.00
IUUC-Loc-051756	Lepisosteus oculatus	39.22	4.00e-96	344.00
IUUC-Lma-053083	Leptosphaeria maculans	32.05	4.00e-52	198.00
IUUC-Laf-054067	Loxodonta africana	41.42	4.00e-91	328.00
IUUC-Mcc-055096	Macaca mulatta	39.67	2.00e-94	338.00
IUUC-Meu-056604	Macropus eugenii	36.04	2.00e-77	282.00
IUUC-Mor-057186	Magnaporthe oryzae	30.10	2.00e-54	205.00
IUUC-Mtr-058346	Medicago truncatula	29.59	4.00e-52	198.00
IUUC-Mla-059116	Melampsora laricipopulina	33.01	1.00e-71	263.00
IUUC-Mga-060038	Meleagris gallopavo	37.14	1.00e-66	246.00
IUUC-Mvi-060272	Microbotryum violaceum	31.02	4.00e-60	224.00
IUUC-Mmr-060877	Microcebus murinus	38.83	2.00e-92	332.00
IUUC-Mdo-062168	Monodelphis domestica	39.83	7.00e-89	320.00
IUUC-Mmu-063441	Mus musculus	38.20	1.00e-92	332.00
IUUC-Mac-065330	Musa acuminata	28.82	3.00e-38	152.00
IUUC-Mpu-065704	Mustela putorius furo	39.46	3.00e-95	341.00
IUUC-Mlu-067640	Myotis lucifugus	39.87	1.00e-94	339.00
IUUC-Nfi-068589	Neosartorya fischeri	31.88	7.00e-45	174.00
IUUC-Ncr-068769	Neurospora crassa	29.55	6.00e-56	211.00
IUUC-Nle-069105	Nomascus leucogenys	40.97	2.00e-89	322.00
IUUC-Opr-070203	Ochotona princeps	37.78	8.00e-100	356.00
IUUC-Ont-072054	Oreochromis niloticus	39.29	5.00e-100	357.00
IUUC-Oan-073624	Ornithorhynchus anatinus	40.31	3.00e-89	321.00
IUUC-Ocu-074326	Oryctolagus cuniculus	39.04	3.00e-90	325.00
IUUC-Obr-076038	Oryza brachyantha	30.61	6.00e-50	191.00
IUUC-Ogl-077463	Oryza glaberrima	29.61	1.00e-52	199.00
IUUC-Ogu-078631	Oryza glumaepatula	29.49	3.00e-55	208.00
IUUC-Oin-079242	Oryza indica	29.61	3.00e-53	202.00
IUUC-Olo-080652	Oryza longistaminata	27.94	1.00e-48	186.00
IUUC-Ome-081109	Oryza meridionalis	30.46	5.00e-47	182.00
IUUC-Oni-082187	Oryza nivara	29.61	3.00e-53	202.00
IUUC-Opu-083995	Oryza punctata	29.30	1.00e-46	179.00
IUUC-Oru-084962	Oryza rufipogon	30.73	9.00e-48	183.00
IUUC-Osa-086201	Oryza sativa	30.96	9.00e-48	183.00
IUUC-Ola-087115	Oryzias latipes	39.04	4.00e-99	354.00
IUUC-Olu-087842	Ostreococcus lucimarinus	29.57	1.00e-56	213.00
IUUC-Oga-088204	Otolemur garnettii	38.23	2.00e-93	335.00
IUUC-Oar-089297	Ovis aries	39.34	6.00e-91	327.00
IUUC-Ptr-090953	Pan troglodytes	39.25	7.00e-93	333.00
IUUC-Pan-092451	Papio anubis	36.69	2.00e-91	328.00
IUUC-Psi-092999	Pelodiscus sinensis	39.80	4.00e-93	334.00
IUUC-Pma-094304	Petromyzon marinus	30.34	4.00e-69	254.00
IUUC-Pno-095060	Phaeosphaeria nodorum	32.21	7.00e-53	201.00
IUUC-Ppa-095433	Physcomitrella patens	33.08	3.00e-76	278.00
IUUC-Pfo-096433	Poecilia formosa	38.21	1.00e-93	336.00
IUUC-Pab-098677	Pongo abelii	39.25	5.00e-93	334.00
IUUC-Pop-099329	Populus trichocarpa	32.69	8.00e-47	180.00
IUUC-Pca-100444	Procavia capensis	48.71	2.00e-67	248.00
IUUC-Ppe-101318	Prunus persica	33.99	2.00e-49	189.00
IUUC-Pva-102162	Pteropus vampyrus	33.13	2.00e-77	281.00
IUUC-Pgr-103329	Puccinia graminis	30.47	3.00e-68	251.00
IUUC-Ptt-103837	Puccinia triticina	29.91	1.00e-69	256.00
IUUC-Pte-104133	Pyrenophora teres	28.79	2.00e-53	202.00
IUUC-Pyt-104675	Pyrenophora triticirepentis	29.17	5.00e-54	204.00
IUUC-Rno-105004	Rattus norvegicus	38.64	9.00e-93	333.00
IUUC-Sce-106443	Saccharomyces cerevisiae	32.08	6.00e-63	234.00
IUUC-Sha-107199	Sarcophilus harrisii	39.60	3.00e-93	335.00
IUUC-Sja-107670	Schizosaccharomyces japonicus	33.27	1.00e-77	283.00
IUUC-Spo-108125	Schizosaccharomyces pombe	33.87	7.00e-77	280.00
IUUC-Ssl-108534	Sclerotinia sclerotiorum	29.67	1.00e-60	226.00
IUUC-Smo-109588	Selaginella moellendorffii	31.38	1.00e-76	279.00
IUUC-Sit-110043	Setaria italica	29.29	3.00e-39	155.00
IUUC-Stu-112396	Solanum tuberosum	31.26	5.00e-64	237.00
IUUC-Sar-113359	Sorex araneus	36.94	3.00e-47	181.00
IUUC-Sre-114995	Sporisorium reilianum	31.93	4.00e-70	258.00
IUUC-Ssc-115397	Sus scrofa	39.67	1.00e-93	336.00
IUUC-Tgu-116834	Taeniopygia guttata	39.67	1.00e-100	359.00
IUUC-Tru-118764	Takifugu rubripes	39.17	6.00e-104	370.00
IUUC-Tsy-119118	Tarsius syrichta	39.04	2.00e-93	335.00
IUUC-Tni-120053	Tetraodon nigroviridis	39.48	4.00e-104	370.00
IUUC-Tca-121842	Theobroma cacao	30.22	2.00e-52	199.00
IUUC-Tre-122172	Trichoderma reesei	30.75	6.00e-62	231.00
IUUC-Tvi-122288	Trichoderma virens	30.45	4.00e-47	181.00
IUUC-Tae-124909	Triticum aestivum	31.22	1.00e-43	169.00
IUUC-Tur-126846	Triticum urartu	43.38	1.00e-23	102.00
IUUC-Tme-127164	Tuber melanosporum	30.20	1.00e-66	246.00
IUUC-Tbe-127458	Tupaia belangeri	39.61	5.00e-90	323.00
IUUC-Ttr-128680	Tursiops truncatus	40.08	5.00e-88	317.00
IUUC-Uma-129508	Ustilago maydis	32.92	1.00e-67	249.00
IUUC-Vda-129696	Verticillium dahliae	33.73	7.00e-48	184.00
IUUC-Vpa-130820	Vicugna pacos	37.95	8.00e-93	333.00
IUUC-Vvi-131126	Vitis vinifera	30.40	8.00e-63	233.00
IUUC-Xtr-131826	Xenopus tropicalis	37.60	5.00e-97	347.00
IUUC-Xma-133373	Xiphophorus maculatus	38.24	5.00e-95	340.00
IUUC-Yli-134432	Yarrowia lipolytica	29.55	1.00e-55	210.00
IUUC-Zma-135241	Zea mays	28.94	5.00e-50	191.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence