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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Cel-018691
Ensembl Protein ID R10E11.1b
UniProt Accession P34545; B0M0M3; CBP1_CAEEL
Genbank Protein ID CAA82353.3; CAD18875.2; CAP72377.2
Protein Name Protein cbp-1
Genbank Nucleotide ID Z29095; Z29095; Z29095
Gene Name cbp-1; R10E11.1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
WBGene00000366 R10E11.1a R10E11.1a
WBGene00000366 R10E11.1b R10E11.1b
WBGene00000366 R10E11.1c R10E11.1c
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNARAID2
Protein-protein Interaction
IIDPINAMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMPhospho.ELMPHOSIDA
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/Other 50.43 0.00e+00 846.00 IUUC-Hsa-046884
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Caenorhabditis elegans
Functional Description
(View)

Functional Description


     Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation (By similarity). May prevent DNA damage-induced apoptosis by inhibiting cep-1-dependent transcription activation of the programmed cell death activator egl-1 (PubMed:19521535).
 Acetyltransferase enzyme. Acetylates histones, giving a specific tag for transcriptional activation (By similarity). May prevent DNA damage-induced apoptosis by inhibiting cep-1-dependent transcription activation of the programmed cell death activator egl-1 (PubMed:19521535).
Protein Sequence
(Fasta)
MDEPPSKKSR ADSDYDSGLD ALSALESLEA FPTSSKDTDV DNNPSTSAGG SGGPSGSTPH 60
PQGTPQPAPS NNGGFNLQPG QSQPQQPPQN MGGGVNGSVL QELLMNPSQT SNNSPRPQAY 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Cel-018691|E3,E3 activity/Other|Caenorhabditis elegans
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AAACAAACAG CTATATCTGG TGATTTTGCC AAACTAACCC AAATAAGCGG GAACTCTGAT 60
GAAGTAGTGG TTGACGTGGG AATTCAAAAA CCGACGGACG CAACCAATTC AGGTGTTCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Cel-018691|E3,E3 activity/Other|Caenorhabditis elegans
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0010--Activator
KW-0012--Acyltransferase
KW-0025--Alternative splicing
KW-0053--Apoptosis
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0479--Metal-binding
KW-0488--Methylation
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
KW-0862--Zinc
KW-0863--Zinc-finger
Interpro

IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR031162--CBP_P300_HAT
IPR013178--Histone_AcTrfase_Rtt109/CBP
IPR003101--KIX_dom
IPR010303--RING_CBP-p300
IPR000197--Znf_TAZ
IPR000433--Znf_ZZ
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51727--CBP_P300_HAT
PS50952--KIX
PS01359--ZF_PHD_1
PS50134--ZF_TAZ
PS01357--ZF_ZZ_1
PS50135--ZF_ZZ_2
Pfam

PF00439--Bromodomain
PF06001--DUF902
PF08214--HAT_KAT11
PF02172--KIX
PF02135--zf-TAZ
PF00569--ZZ
PRINTS

PR00503--BROMODOMAIN
SMART

SM00297--BROMO
SM01250--KAT11
SM00551--ZnF_TAZ
SM00291--ZnF_ZZ
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0004402--F:histone acetyltransferase activity
GO:0004468--F:lysine N-acetyltransferase activity, acting on acetyl phosphate as donor
GO:0061733--F:peptide-lysine-N-acetyltransferase activity
GO:0061629--F:RNA polymerase II sequence-specific DNA binding transcription factor binding
GO:0003712--F:transcription cofactor activity
GO:0008134--F:transcription factor binding
GO:0008270--F:zinc ion binding
GO:0006915--P:apoptotic process
GO:0009792--P:embryo development ending in birth or egg hatching
GO:0016573--P:histone acetylation
GO:0018393--P:internal peptidyl-lysine acetylation
GO:0043065--P:positive regulation of apoptotic process
GO:0045944--P:positive regulation of transcription from RNA polymerase II promoter
GO:0010975--P:regulation of neuron projection development
GO:0006355--P:regulation of transcription, DNA-templated
GO:0007283--P:spermatogenesis
GO:0006351--P:transcription, DNA-templated
KEGG cel:CELE_R10E11.1
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001156 Aegilops tauschii 33.73 7.00e-61 228.00
IUUC-Aml-002027 Ailuropoda melanoleuca 51.79 0.00e+00 816.00
IUUC-Apl-003917 Anas platyrhynchos 53.24 8.00e-167 581.00
IUUC-Aca-005040 Anolis carolinensis 52.80 6.00e-170 591.00
IUUC-Ath-007233 Arabidopsis thaliana 35.25 4.00e-66 246.00
IUUC-Ame-011395 Astyanax mexicanus 53.83 6.00e-167 581.00
IUUC-Bta-012649 Bos taurus 51.66 0.00e+00 812.00
IUUC-Bdi-014481 Brachypodium distachyon 34.36 3.00e-64 239.00
IUUC-Bol-016000 Brassica oleracea 36.14 4.00e-68 252.00
IUUC-Bra-018090 Brassica rapa 36.14 2.00e-68 253.00
IUUC-Cja-019649 Callithrix jacchus 52.19 0.00e+00 817.00
IUUC-Cfa-020764 Canis familiaris 49.17 0.00e+00 813.00
IUUC-Cpo-022345 Cavia porcellus 51.34 0.00e+00 807.00
IUUC-Cre-022852 Chlamydomonas reinhardtii 30.96 2.00e-55 210.00
IUUC-Csa-023866 Chlorocebus sabaeus 51.79 0.00e+00 816.00
IUUC-Cho-024951 Choloepus hoffmanni 53.32 1.00e-171 597.00
IUUC-Cin-025624 Ciona intestinalis 48.17 0.00e+00 822.00
IUUC-Csv-026122 Ciona savignyi 51.39 6.00e-152 530.00
IUUC-Cme-027299 Cyanidioschyzon merolae 24.04 3.50e-01 28.50
IUUC-Dre-027824 Danio rerio 52.16 0.00e+00 831.00
IUUC-Dno-029638 Dasypus novemcinctus 52.03 3.00e-164 572.00
IUUC-Dor-030279 Dipodomys ordii 48.97 1.00e-136 480.00
IUUC-Dme-031716 Drosophila melanogaster 52.04 9.00e-163 568.00
IUUC-Ete-032742 Echinops telfairi 52.09 2.00e-160 559.00
IUUC-Eca-034048 Equus caballus 51.53 0.00e+00 814.00
IUUC-Eeu-035154 Erinaceus europaeus 54.21 5.00e-157 548.00
IUUC-Fca-035891 Felis catus 51.79 0.00e+00 816.00
IUUC-Fal-037585 Ficedula albicollis 50.81 0.00e+00 822.00
IUUC-Gmo-039348 Gadus morhua 51.13 1.00e-162 567.00
IUUC-Gga-040916 Gallus gallus 50.94 0.00e+00 837.00
IUUC-Gac-042302 Gasterosteus aculeatus 49.24 0.00e+00 826.00
IUUC-Ggo-045189 Gorilla gorilla 51.79 0.00e+00 816.00
IUUC-Hsa-046884 Homo sapiens 51.79 0.00e+00 816.00
IUUC-Hvu-047619 Hordeum vulgare 33.81 1.00e-61 231.00
IUUC-Itr-048564 Ictidomys tridecemlineatus 54.15 2.00e-166 578.00
IUUC-Loc-052536 Lepisosteus oculatus 52.82 1.00e-167 583.00
IUUC-Laf-054423 Loxodonta africana 51.79 0.00e+00 819.00
IUUC-Mcc-054847 Macaca mulatta 51.79 0.00e+00 816.00
IUUC-Meu-056217 Macropus eugenii 47.85 0.00e+00 805.00
IUUC-Mtr-058740 Medicago truncatula 34.06 4.00e-63 236.00
IUUC-Mga-059250 Meleagris gallopavo 53.11 5.00e-171 595.00
IUUC-Mmr-061496 Microcebus murinus 51.79 0.00e+00 817.00
IUUC-Mdo-062478 Monodelphis domestica 49.36 0.00e+00 837.00
IUUC-Mmu-063456 Mus musculus 51.78 0.00e+00 812.00
IUUC-Mac-064767 Musa acuminata 34.93 1.00e-65 244.00
IUUC-Mpu-065963 Mustela putorius furo 51.79 0.00e+00 818.00
IUUC-Mlu-067185 Myotis lucifugus 50.81 0.00e+00 810.00
IUUC-Nle-069907 Nomascus leucogenys 51.19 0.00e+00 818.00
IUUC-Opr-070324 Ochotona princeps 43.10 3.00e-119 422.00
IUUC-Ont-071852 Oreochromis niloticus 51.72 0.00e+00 822.00
IUUC-Oan-073723 Ornithorhynchus anatinus 51.28 0.00e+00 834.00
IUUC-Ocu-074707 Oryctolagus cuniculus 52.19 0.00e+00 816.00
IUUC-Oba-075590 Oryza barthii 35.12 7.00e-66 245.00
IUUC-Ogu-078580 Oryza glumaepatula 34.94 2.00e-66 246.00
IUUC-Oin-079283 Oryza indica 35.02 1.00e-65 244.00
IUUC-Olo-080969 Oryza longistaminata 35.02 2.00e-65 243.00
IUUC-Ome-081615 Oryza meridionalis 35.12 7.00e-66 245.00
IUUC-Oni-082636 Oryza nivara 35.12 7.00e-66 245.00
IUUC-Opu-084073 Oryza punctata 35.12 4.00e-66 246.00
IUUC-Oru-084994 Oryza rufipogon 35.12 7.00e-66 245.00
IUUC-Osa-085860 Oryza sativa 45.58 4.00e-58 219.00
IUUC-Ola-086899 Oryzias latipes 48.33 0.00e+00 813.00
IUUC-Olu-087701 Ostreococcus lucimarinus 32.70 2.00e-60 226.00
IUUC-Oga-088700 Otolemur garnettii 51.66 0.00e+00 816.00
IUUC-Oar-089787 Ovis aries 51.66 0.00e+00 810.00
IUUC-Ptr-091620 Pan troglodytes 51.66 0.00e+00 815.00
IUUC-Pan-092166 Papio anubis 51.79 0.00e+00 816.00
IUUC-Psi-093992 Pelodiscus sinensis 52.69 4.00e-170 592.00
IUUC-Pma-094328 Petromyzon marinus 59.79 2.00e-108 385.00
IUUC-Ppa-095569 Physcomitrella patens 35.36 1.00e-66 247.00
IUUC-Pfo-096203 Poecilia formosa 52.67 8.00e-167 581.00
IUUC-Pab-098235 Pongo abelii 51.79 0.00e+00 817.00
IUUC-Pop-098947 Populus trichocarpa 33.33 1.00e-63 238.00
IUUC-Pca-100780 Procavia capensis 51.08 0.00e+00 747.00
IUUC-Ppe-101498 Prunus persica 32.62 2.00e-59 223.00
IUUC-Pva-103071 Pteropus vampyrus 50.37 0.00e+00 824.00
IUUC-Sha-106736 Sarcophilus harrisii 49.24 0.00e+00 835.00
IUUC-Smo-109420 Selaginella moellendorffii 34.00 3.00e-61 229.00
IUUC-Sit-110128 Setaria italica 34.38 2.00e-65 243.00
IUUC-Stu-112845 Solanum tuberosum 32.99 1.00e-58 219.00
IUUC-Sar-113479 Sorex araneus 41.18 1.00e-96 348.00
IUUC-Sbi-114827 Sorghum bicolor 35.11 8.00e-68 251.00
IUUC-Ssc-116077 Sus scrofa 49.63 1.00e-169 590.00
IUUC-Tgu-116872 Taeniopygia guttata 50.12 0.00e+00 824.00
IUUC-Tru-118390 Takifugu rubripes 48.00 0.00e+00 823.00
IUUC-Tsy-119451 Tarsius syrichta 48.97 6.00e-129 455.00
IUUC-Tca-121835 Theobroma cacao 34.22 2.00e-64 240.00
IUUC-Tae-125906 Triticum aestivum 33.57 6.00e-61 228.00
IUUC-Tur-126284 Triticum urartu 33.98 6.00e-61 228.00
IUUC-Tbe-127772 Tupaia belangeri 43.85 5.00e-91 329.00
IUUC-Ttr-128447 Tursiops truncatus 52.03 2.00e-165 577.00
IUUC-Vpa-130766 Vicugna pacos 52.11 3.00e-167 582.00
IUUC-Xtr-131854 Xenopus tropicalis 54.39 3.00e-169 589.00
Created Date 25-Jun-2017

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