iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.80e-31	105.3	179	210
UBD/Beta-Prp	5.10e-41	139.2	82	229

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclafsd.tllvsGsdDgtikvWDlr 31
           gHt+ +++++f+d  +++++s+D t+ +WD+ 
   Q: 179  GHTCYISDIEFTDnAHILTASGDMTCALWDIP 210
           8**********55599**************75 PP

UBD/Beta-Prp

   S: 84   gkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdl.....ktgkllrtltggh 179
            k+ ++lkgh++++ + ++s+++++++s+s+d    +wd  +g + +      +++v + +++p++ l++s++l++ + ++++       +++   ++g h
   Q: 82   LKPNIVLKGHNNKISDFRWSRDSKRILSASQDGFMLIWDSASGLKQN-AIPLDSQWVLSCAISPSSTLVASAGLNNNCTIYRVskenrVAQNVASIFKG-H 180
           567789****************************************9.7788889****************************7766666666667798.* PP
   S: 180  tdsvyslsfdsngkelvsgsldgtvklwdlqtgecvrtlnghtdnvksvr 229
           t ++  ++f++n  +++++s d t  lwd+ + + vr++ +h   v+ ++
   Q: 181  TCYISDIEFTDN-AHILTASGDMTCALWDIPKAKRVREYSDHLGDVLALA 229
           ***********8.7****************************99988765 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

G proteins are composed of 3 units, alpha, beta and gamma. The beta-gamma subunit complex (STE4-STE18 complex) interacts with PLP1 and PLP2. Interacts with SYG1.

Protein Sequence
(Fasta)

MAAHQMDSIT YSNNVTQQYI QPQSLQDISA VEDEIQNKIE AARQESKQLH AQINKAKHKI 60
QDASLFQMAN KVTSLTKNKI NLKPNIVLKG HNNKISDFRW SRDSKRILSA SQDGFMLIWD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGCAGCAC ATCAGATGGA CTCGATAACG TATTCTAATA ATGTCACCCA ACAGTATATA 60
CAACCACAAA GTCTACAGGA TATCTCTGCA GTGGAGGATG AAATTCAAAA TAAAATAGAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0589--Pheromone response
KW-1185--Reference proteome
KW-0677--Repeat
KW-0807--Transducer
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR016346--Guanine_nucleotide-bd_bsu
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005834--C:heterotrimeric G-protein complex
GO:0005937--C:mating projection
GO:0005886--C:plasma membrane
GO:0004871--F:signal transducer activity
GO:0043577--P:chemotropism
GO:0031684--P:heterotrimeric G-protein complex cycle
GO:0001403--P:invasive growth in response to glucose limitation
GO:0000750--P:pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0010525--P:regulation of transposition, RNA-mediated

KEGG

sce:YOR212W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000161	Aegilops tauschii	30.70	1.00e-42	164.00
IUUC-Aml-001727	Ailuropoda melanoleuca	37.13	3.00e-64	236.00
IUUC-Atr-002610	Amborella trichopoda	31.73	4.00e-52	196.00
IUUC-Apl-004079	Anas platyrhynchos	36.39	4.00e-66	242.00
IUUC-Aca-004861	Anolis carolinensis	35.50	3.00e-68	249.00
IUUC-Aly-006025	Arabidopsis lyrata	32.63	2.00e-52	197.00
IUUC-Ath-006617	Arabidopsis thaliana	32.63	4.00e-52	196.00
IUUC-Ago-007831	Ashbya gossypii	57.27	1.00e-136	477.00
IUUC-Acl-008154	Aspergillus clavatus	39.90	3.00e-77	280.00
IUUC-Afl-008568	Aspergillus flavus	40.05	1.00e-79	287.00
IUUC-Afu-008789	Aspergillus fumigatus	39.69	9.00e-77	278.00
IUUC-Ani-009213	Aspergillus nidulans	39.79	2.00e-78	283.00
IUUC-Ang-009836	Aspergillus niger	40.31	2.00e-80	290.00
IUUC-Aor-010165	Aspergillus oryzae	40.05	1.00e-79	287.00
IUUC-Ate-010520	Aspergillus terreus	34.79	4.00e-53	199.00
IUUC-Ame-011205	Astyanax mexicanus	40.00	2.00e-66	243.00
IUUC-Bgr-012079	Blumeria graminis	38.74	2.00e-74	270.00
IUUC-Bta-013200	Bos taurus	37.13	2.00e-64	236.00
IUUC-Bci-013621	Botrytis cinerea	37.89	2.00e-71	260.00
IUUC-Bdi-014785	Brachypodium distachyon	32.26	1.00e-51	194.00
IUUC-Bol-015759	Brassica oleracea	34.29	4.00e-48	184.00
IUUC-Bra-016695	Brassica rapa	33.42	3.00e-49	187.00
IUUC-Cel-018704	Caenorhabditis elegans	36.10	7.00e-69	251.00
IUUC-Cja-019845	Callithrix jacchus	37.13	2.00e-64	237.00
IUUC-Cfa-020395	Canis familiaris	37.13	3.00e-64	236.00
IUUC-Cpo-021398	Cavia porcellus	36.32	5.00e-69	252.00
IUUC-Csa-023295	Chlorocebus sabaeus	37.13	3.00e-64	236.00
IUUC-Cho-024766	Choloepus hoffmanni	37.03	2.00e-64	236.00
IUUC-Cin-025309	Ciona intestinalis	34.90	4.00e-68	249.00
IUUC-Csv-026258	Ciona savignyi	35.42	2.00e-68	250.00
IUUC-Cgl-026673	Colletotrichum gloeosporioides	38.15	1.00e-76	278.00
IUUC-Cne-026811	Cryptococcus neoformans	37.05	2.00e-72	264.00
IUUC-Dre-028432	Danio rerio	38.04	1.00e-65	241.00
IUUC-Dno-029001	Dasypus novemcinctus	35.77	8.00e-62	229.00
IUUC-Dor-030322	Dipodomys ordii	32.25	2.00e-48	184.00
IUUC-Dse-031388	Dothistroma septosporum	37.73	3.00e-76	276.00
IUUC-Dme-031748	Drosophila melanogaster	35.32	1.00e-65	240.00
IUUC-Ete-032710	Echinops telfairi	37.54	7.00e-61	225.00
IUUC-Eca-033628	Equus caballus	37.13	4.00e-64	236.00
IUUC-Eeu-035079	Erinaceus europaeus	35.27	3.00e-69	253.00
IUUC-Fca-035392	Felis catus	35.77	3.00e-67	246.00
IUUC-Fal-037345	Ficedula albicollis	36.15	3.00e-69	253.00
IUUC-Fox-037946	Fusarium oxysporum	38.14	9.00e-72	261.00
IUUC-Fso-038136	Fusarium solani	37.66	7.00e-72	261.00
IUUC-Gmo-039222	Gadus morhua	37.10	9.00e-67	244.00
IUUC-Ggr-039969	Gaeumannomyces graminis	38.40	7.00e-75	271.00
IUUC-Gga-040320	Gallus gallus	35.90	6.00e-69	252.00
IUUC-Gac-042161	Gasterosteus aculeatus	37.86	5.00e-70	255.00
IUUC-Gma-044308	Glycine max	33.91	2.00e-52	197.00
IUUC-Ggo-044954	Gorilla gorilla	37.13	2.00e-64	236.00
IUUC-Hsa-046105	Homo sapiens	37.13	3.00e-64	236.00
IUUC-Hvu-047596	Hordeum vulgare	32.61	1.00e-51	195.00
IUUC-Itr-048501	Ictidomys tridecemlineatus	36.13	6.00e-67	245.00
IUUC-Kpa-049192	Komagataella pastoris	39.49	5.00e-79	285.00
IUUC-Lch-049422	Latimeria chalumnae	36.27	4.00e-63	233.00
IUUC-Lpe-051040	Leersia perrieri	31.11	1.00e-52	198.00
IUUC-Loc-052790	Lepisosteus oculatus	36.86	7.00e-65	239.00
IUUC-Lma-052985	Leptosphaeria maculans	38.56	4.00e-78	282.00
IUUC-Laf-054255	Loxodonta africana	34.95	2.00e-67	247.00
IUUC-Mcc-055787	Macaca mulatta	37.13	3.00e-64	236.00
IUUC-Meu-056902	Macropus eugenii	35.77	9.00e-62	228.00
IUUC-Mor-057188	Magnaporthe oryzae	38.08	3.00e-74	270.00
IUUC-Mpo-057544	Magnaporthe poae	38.14	3.00e-75	273.00
IUUC-Mtr-058752	Medicago truncatula	31.77	1.00e-53	201.00
IUUC-Mla-059086	Melampsora laricipopulina	40.05	9.00e-77	278.00
IUUC-Mga-059516	Meleagris gallopavo	36.29	4.00e-66	243.00
IUUC-Mvi-060482	Microbotryum violaceum	40.16	1.00e-79	288.00
IUUC-Mmr-060931	Microcebus murinus	37.13	3.00e-64	236.00
IUUC-Mdo-062619	Monodelphis domestica	35.38	3.00e-68	249.00
IUUC-Mmu-064266	Mus musculus	34.54	2.00e-68	250.00
IUUC-Mac-064871	Musa acuminata	30.45	2.00e-52	197.00
IUUC-Mpu-066358	Mustela putorius furo	37.13	3.00e-64	236.00
IUUC-Mlu-067628	Myotis lucifugus	36.29	7.00e-68	248.00
IUUC-Nfi-068332	Neosartorya fischeri	39.90	3.00e-77	279.00
IUUC-Ncr-068650	Neurospora crassa	37.21	4.00e-72	262.00
IUUC-Nle-069612	Nomascus leucogenys	37.13	3.00e-64	236.00
IUUC-Opr-070866	Ochotona princeps	35.77	6.00e-62	228.00
IUUC-Ont-071338	Oreochromis niloticus	38.32	2.00e-68	249.00
IUUC-Oan-072913	Ornithorhynchus anatinus	36.86	2.00e-59	220.00
IUUC-Ocu-074126	Oryctolagus cuniculus	36.59	8.00e-64	235.00
IUUC-Oba-075818	Oryza barthii	33.83	4.00e-49	186.00
IUUC-Obr-076229	Oryza brachyantha	30.52	7.00e-49	186.00
IUUC-Ogl-077730	Oryza glaberrima	32.53	1.00e-52	197.00
IUUC-Ogu-078583	Oryza glumaepatula	33.11	2.00e-39	153.00
IUUC-Oin-079661	Oryza indica	30.52	8.00e-49	185.00
IUUC-Olo-080225	Oryza longistaminata	33.11	2.00e-39	153.00
IUUC-Oni-082161	Oryza nivara	32.53	2.00e-52	197.00
IUUC-Opu-084072	Oryza punctata	32.80	5.00e-53	199.00
IUUC-Oru-084316	Oryza rufipogon	30.52	8.00e-49	185.00
IUUC-Osa-085380	Oryza sativa	30.52	8.00e-49	185.00
IUUC-Ola-086578	Oryzias latipes	37.60	8.00e-66	241.00
IUUC-Oga-089046	Otolemur garnettii	35.77	6.00e-62	228.00
IUUC-Oar-089360	Ovis aries	37.13	3.00e-64	236.00
IUUC-Ptr-091437	Pan troglodytes	37.13	3.00e-64	236.00
IUUC-Pan-092195	Papio anubis	37.13	2.00e-64	237.00
IUUC-Psi-092965	Pelodiscus sinensis	36.81	5.00e-67	245.00
IUUC-Pma-094692	Petromyzon marinus	39.83	1.00e-43	167.00
IUUC-Pno-095135	Phaeosphaeria nodorum	38.30	1.00e-77	281.00
IUUC-Ppa-095726	Physcomitrella patens	29.51	8.00e-47	178.00
IUUC-Pfo-097165	Poecilia formosa	38.38	9.00e-69	251.00
IUUC-Pab-098157	Pongo abelii	35.50	4.00e-68	250.00
IUUC-Pop-099370	Populus trichocarpa	32.62	6.00e-53	199.00
IUUC-Pca-100940	Procavia capensis	35.77	6.00e-62	228.00
IUUC-Ppe-102016	Prunus persica	29.95	1.00e-52	197.00
IUUC-Pva-102666	Pteropus vampyrus	36.29	2.00e-67	247.00
IUUC-Pgr-103321	Puccinia graminis	40.31	3.00e-77	280.00
IUUC-Ptt-103728	Puccinia triticina	40.31	3.00e-77	280.00
IUUC-Pte-104053	Pyrenophora teres	38.30	7.00e-78	281.00
IUUC-Pyt-104426	Pyrenophora triticirepentis	35.44	1.00e-66	244.00
IUUC-Rno-106104	Rattus norvegicus	35.77	6.00e-62	228.00
IUUC-Sha-106754	Sarcophilus harrisii	36.68	5.00e-65	239.00
IUUC-Sja-107891	Schizosaccharomyces japonicus	27.14	2.00e-37	147.00
IUUC-Spo-108352	Schizosaccharomyces pombe	30.14	1.00e-42	164.00
IUUC-Ssl-108539	Sclerotinia sclerotiorum	37.89	2.00e-71	260.00
IUUC-Smo-109652	Selaginella moellendorffii	31.55	4.00e-49	186.00
IUUC-Sit-110441	Setaria italica	31.99	1.00e-51	194.00
IUUC-Sly-111784	Solanum lycopersicum	31.28	2.00e-52	197.00
IUUC-Stu-112400	Solanum tuberosum	31.28	3.00e-52	196.00
IUUC-Sar-113642	Sorex araneus	38.41	7.00e-56	208.00
IUUC-Sbi-114038	Sorghum bicolor	32.58	2.00e-50	191.00
IUUC-Sre-115035	Sporisorium reilianum	37.76	2.00e-75	274.00
IUUC-Ssc-115390	Sus scrofa	34.79	2.00e-68	250.00
IUUC-Tgu-117198	Taeniopygia guttata	36.86	1.00e-59	221.00
IUUC-Tru-118056	Takifugu rubripes	38.12	3.00e-69	253.00
IUUC-Tsy-119354	Tarsius syrichta	37.13	3.00e-64	236.00
IUUC-Tni-120669	Tetraodon nigroviridis	37.01	5.00e-64	235.00
IUUC-Tca-121224	Theobroma cacao	31.82	3.00e-51	193.00
IUUC-Tre-122156	Trichoderma reesei	37.63	2.00e-75	273.00
IUUC-Tvi-122640	Trichoderma virens	37.63	2.00e-75	273.00
IUUC-Tae-125653	Triticum aestivum	32.61	9.00e-52	195.00
IUUC-Tur-126755	Triticum urartu	32.43	3.00e-51	195.00
IUUC-Tme-126886	Tuber melanosporum	40.93	3.00e-76	276.00
IUUC-Tbe-127469	Tupaia belangeri	34.03	1.00e-62	231.00
IUUC-Ttr-129243	Tursiops truncatus	37.13	3.00e-64	236.00
IUUC-Uma-129589	Ustilago maydis	38.27	5.00e-76	275.00
IUUC-Vda-129855	Verticillium dahliae	39.94	6.00e-70	255.00
IUUC-Vpa-130173	Vicugna pacos	35.77	1.00e-43	168.00
IUUC-Vvi-131162	Vitis vinifera	32.09	1.00e-53	201.00
IUUC-Xtr-132928	Xenopus tropicalis	36.49	4.00e-64	236.00
IUUC-Xma-133368	Xiphophorus maculatus	38.12	3.00e-68	249.00
IUUC-Yli-134396	Yarrowia lipolytica	28.71	2.00e-52	197.00
IUUC-Zma-135893	Zea mays	32.58	9.00e-51	191.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence