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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-046532
Ensembl Protein ID ENSP00000376139.4
UniProt Accession Q5MNZ6; O95328; Q2MCP6; Q6IBN2; WIPI3_HUMAN
Genbank Protein ID CAJ57996.1; EAW89810.1; AAC72952.1; AAV80763.1; CAG33051.1
Protein Name WD repeat domain phosphoinositide-interacting protein 3; WD repeat-containing protein 45-like; WD repeat-containing protein 45B; WIPI49-like protein
Genbank Nucleotide ID AM182326; CH471099; AF091083; AY691427; CR456770
Gene Name WDR45B; WDR45L; WIPI3
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000141580.15 ENST00000392325.8 ENSP00000376139.4
ENSG00000141580.15 ENST00000572583.5 ENSP00000461488.1
ENSG00000141580.15 ENST00000576517.1 ENSP00000460297.1
ENSG00000141580.15 ENST00000573616.5 ENSP00000458738.1
ENSG00000141580.15 ENST00000571817.5 ENSP00000461355.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICHPM
DNA & RNA Element
UTRdbAREsitecircRNADbCircNet
miRTarBasemicroRNATRANSFACTargetScan
RepTarSomamiRmiRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
ClinVarOMIM
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGCCOSMIC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.00e-09 39.1 184 222
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sdtllvsGsdDgt.ikvWDlrtgvllk 37
           H++  +c+a+  ++t+++++s  gt i+++D+++g+l++
   Q: 184  HEGVLSCIALnlQGTRIATASEKGTlIRIFDTSSGHLIQ 222
           9999******9777********************99887 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MNLLPCNPHG NGLLYAGFNQ DHGCFACGME NGFRVYNTDP LKEKEKQEFL EGGVGHVEML 60
FRCNYLALVG GGKKPKYPPN KVMIWDDLKK KTVIEIEFST EVKAVKLRRD RIVVVLDSMI 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-046532|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGCTCCATAG GCTCCCTGGT GGGGCGCGGG CGCGCGCACG GACGTCCAGC ACGCACGCAC 60
GCACGTCCAG CACACACGCA CATCCAGCAC GCACGCACGT ACGTCCGGCA CTTCCGGCCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-046532|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
SMART

SM00320--WD40
KEGG hsa:56270
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000966 Aegilops tauschii 44.23 7.00e-78 284.00
IUUC-Aml-001504 Ailuropoda melanoleuca 99.71 0.00e+00 658.00
IUUC-Atr-002710 Amborella trichopoda 43.51 3.00e-73 268.00
IUUC-Apl-003741 Anas platyrhynchos 98.14 2.00e-174 604.00
IUUC-Aca-004629 Anolis carolinensis 96.51 0.00e+00 643.00
IUUC-Aly-006440 Arabidopsis lyrata 43.07 1.00e-64 240.00
IUUC-Ath-006629 Arabidopsis thaliana 44.21 9.00e-66 244.00
IUUC-Ame-011233 Astyanax mexicanus 95.93 0.00e+00 640.00
IUUC-Bta-012842 Bos taurus 98.84 0.00e+00 657.00
IUUC-Bdi-014739 Brachypodium distachyon 43.96 1.00e-78 286.00
IUUC-Bol-015119 Brassica oleracea 44.41 5.00e-67 248.00
IUUC-Bra-017319 Brassica rapa 44.88 4.00e-67 248.00
IUUC-Cja-018855 Callithrix jacchus 99.68 3.00e-173 600.00
IUUC-Cfa-020539 Canis familiaris 99.68 2.00e-172 597.00
IUUC-Cpo-021981 Cavia porcellus 100.00 0.00e+00 662.00
IUUC-Cre-022613 Chlamydomonas reinhardtii 33.85 5.00e-31 129.00
IUUC-Csa-023140 Chlorocebus sabaeus 100.00 0.00e+00 662.00
IUUC-Cin-025655 Ciona intestinalis 63.96 4.00e-117 414.00
IUUC-Csv-025977 Ciona savignyi 63.66 1.00e-123 436.00
IUUC-Dre-028091 Danio rerio 95.93 0.00e+00 639.00
IUUC-Dno-029987 Dasypus novemcinctus 97.97 0.00e+00 652.00
IUUC-Dme-031881 Drosophila melanogaster 67.93 9.00e-134 469.00
IUUC-Ete-032771 Echinops telfairi 86.64 6.00e-122 429.00
IUUC-Eca-033323 Equus caballus 100.00 2.00e-177 615.00
IUUC-Eeu-034479 Erinaceus europaeus 98.71 8.00e-127 446.00
IUUC-Fca-035675 Felis catus 97.87 3.00e-177 614.00
IUUC-Fal-037218 Ficedula albicollis 97.09 0.00e+00 644.00
IUUC-Fso-038422 Fusarium solani 32.18 6.00e-49 187.00
IUUC-Ggr-039909 Gaeumannomyces graminis 37.80 2.00e-52 199.00
IUUC-Gga-040977 Gallus gallus 97.38 0.00e+00 645.00
IUUC-Gac-042096 Gasterosteus aculeatus 95.35 0.00e+00 659.00
IUUC-Gma-043922 Glycine max 45.85 2.00e-75 276.00
IUUC-Ggo-045466 Gorilla gorilla 80.52 3.00e-147 514.00
IUUC-Hvu-047851 Hordeum vulgare 44.23 5.00e-78 284.00
IUUC-Itr-048277 Ictidomys tridecemlineatus 99.71 0.00e+00 661.00
IUUC-Lch-049800 Latimeria chalumnae 95.64 0.00e+00 640.00
IUUC-Lpe-051205 Leersia perrieri 44.93 6.00e-78 284.00
IUUC-Loc-052379 Lepisosteus oculatus 97.20 5.00e-173 600.00
IUUC-Laf-054084 Loxodonta africana 93.23 5.00e-171 593.00
IUUC-Mcc-055304 Macaca mulatta 100.00 2.00e-173 601.00
IUUC-Meu-056020 Macropus eugenii 87.70 5.00e-141 493.00
IUUC-Mpo-057416 Magnaporthe poae 39.37 5.00e-54 205.00
IUUC-Mtr-058609 Medicago truncatula 45.29 3.00e-65 242.00
IUUC-Mla-058885 Melampsora laricipopulina 37.50 1.00e-37 149.00
IUUC-Mga-060051 Meleagris gallopavo 96.08 3.00e-176 610.00
IUUC-Mmr-061076 Microcebus murinus 91.91 4.00e-171 593.00
IUUC-Mdo-062465 Monodelphis domestica 98.55 0.00e+00 653.00
IUUC-Mmu-063289 Mus musculus 99.13 0.00e+00 656.00
IUUC-Mac-064838 Musa acuminata 42.43 2.00e-75 276.00
IUUC-Mpu-066052 Mustela putorius furo 98.76 4.00e-176 610.00
IUUC-Mlu-067972 Myotis lucifugus 99.71 0.00e+00 660.00
IUUC-Nfi-068596 Neosartorya fischeri 36.07 5.00e-54 204.00
IUUC-Nle-069047 Nomascus leucogenys 100.00 1.00e-176 611.00
IUUC-Ont-071875 Oreochromis niloticus 95.93 0.00e+00 663.00
IUUC-Ocu-074736 Oryctolagus cuniculus 91.19 5.00e-162 563.00
IUUC-Oba-075827 Oryza barthii 44.23 4.00e-78 285.00
IUUC-Obr-076476 Oryza brachyantha 43.96 9.00e-78 283.00
IUUC-Ogl-077630 Oryza glaberrima 44.23 4.00e-78 285.00
IUUC-Ogu-078126 Oryza glumaepatula 44.51 2.00e-78 286.00
IUUC-Oin-080115 Oryza indica 44.23 4.00e-78 285.00
IUUC-Olo-080657 Oryza longistaminata 45.66 6.00e-77 283.00
IUUC-Ome-081702 Oryza meridionalis 45.72 5.00e-75 275.00
IUUC-Oni-082884 Oryza nivara 44.93 6.00e-78 285.00
IUUC-Opu-083460 Oryza punctata 44.93 2.00e-77 284.00
IUUC-Oru-084193 Oryza rufipogon 44.23 4.00e-78 285.00
IUUC-Osa-085948 Oryza sativa 44.23 4.00e-78 285.00
IUUC-Ola-086628 Oryzias latipes 94.77 0.00e+00 658.00
IUUC-Olu-087808 Ostreococcus lucimarinus 41.57 5.00e-72 264.00
IUUC-Oga-088642 Otolemur garnettii 100.00 0.00e+00 662.00
IUUC-Oar-089538 Ovis aries 93.91 6.00e-177 613.00
IUUC-Ptr-091326 Pan troglodytes 100.00 0.00e+00 662.00
IUUC-Pan-091795 Papio anubis 100.00 0.00e+00 662.00
IUUC-Psi-093258 Pelodiscus sinensis 97.83 1.00e-174 605.00
IUUC-Pno-094851 Phaeosphaeria nodorum 34.08 2.00e-44 173.00
IUUC-Ppa-095480 Physcomitrella patens 43.42 7.00e-71 261.00
IUUC-Pfo-096099 Poecilia formosa 95.64 0.00e+00 662.00
IUUC-Pab-098681 Pongo abelii 100.00 0.00e+00 662.00
IUUC-Pop-099760 Populus trichocarpa 44.89 1.00e-77 283.00
IUUC-Ppe-101963 Prunus persica 45.40 6.00e-66 244.00
IUUC-Pva-103006 Pteropus vampyrus 99.38 6.00e-176 609.00
IUUC-Pgr-103258 Puccinia graminis 36.08 1.00e-40 161.00
IUUC-Ptt-103915 Puccinia triticina 34.63 4.00e-38 152.00
IUUC-Pte-104115 Pyrenophora teres 35.05 5.00e-46 178.00
IUUC-Rno-106112 Rattus norvegicus 99.13 0.00e+00 656.00
IUUC-Sce-106327 Saccharomyces cerevisiae 29.58 2.00e-35 143.00
IUUC-Sha-107573 Sarcophilus harrisii 98.26 0.00e+00 652.00
IUUC-Sja-107791 Schizosaccharomyces japonicus 34.78 2.00e-44 172.00
IUUC-Spo-108254 Schizosaccharomyces pombe 34.16 5.00e-41 161.00
IUUC-Smo-109446 Selaginella moellendorffii 43.21 2.00e-81 296.00
IUUC-Sit-110095 Setaria italica 43.96 4.00e-78 285.00
IUUC-Sly-111030 Solanum lycopersicum 40.77 1.00e-70 259.00
IUUC-Stu-111954 Solanum tuberosum 44.12 1.00e-66 247.00
IUUC-Sar-113276 Sorex araneus 88.05 3.00e-109 387.00
IUUC-Sbi-114020 Sorghum bicolor 43.41 1.00e-77 283.00
IUUC-Ssc-116163 Sus scrofa 98.55 0.00e+00 658.00
IUUC-Tgu-116488 Taeniopygia guttata 97.52 8.00e-173 599.00
IUUC-Tru-118329 Takifugu rubripes 95.06 0.00e+00 689.00
IUUC-Tni-119729 Tetraodon nigroviridis 87.39 0.00e+00 634.00
IUUC-Tca-121459 Theobroma cacao 44.69 4.00e-61 228.00
IUUC-Tre-122255 Trichoderma reesei 32.97 4.00e-51 195.00
IUUC-Tvi-122643 Trichoderma virens 34.77 9.00e-56 210.00
IUUC-Tae-123911 Triticum aestivum 44.23 3.00e-78 285.00
IUUC-Tur-126757 Triticum urartu 43.96 5.00e-78 284.00
IUUC-Ttr-128940 Tursiops truncatus 98.99 7.00e-160 556.00
IUUC-Vda-129980 Verticillium dahliae 30.33 1.00e-42 166.00
IUUC-Vvi-131053 Vitis vinifera 45.69 4.00e-76 278.00
IUUC-Xtr-131806 Xenopus tropicalis 97.09 0.00e+00 646.00
IUUC-Xma-134275 Xiphophorus maculatus 95.64 0.00e+00 662.00
IUUC-Yli-134566 Yarrowia lipolytica 33.91 1.00e-58 220.00
Created Date 25-Jun-2017

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