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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Hsa-045976
Ensembl Protein ID ENSP00000314193.4
UniProt Accession Q8IWA0; Q96J10; Q9H8U8; Q9H9U5; Q9H9V8; Q9UIX2; WDR75_HUMAN
Genbank Protein ID CAB59265.1; CAH18278.1; AAX93081.1; AAH40567.1; AAH06816.1; BAB14111.1; BAB14126.1; BAB14503.1
Protein Name WD repeat-containing protein 75; U3 small nucleolar RNA-associated protein 17 homolog
Genbank Nucleotide ID AL122097; CR749440; AC013439; BC040567; BC006816; AK022581; AK022607; AK023276
Gene Name WDR75; UTP17
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSG00000115368.9 ENST00000314761.8 ENSP00000314193.4
ENSG00000115368.9 ENST00000436347.5 ENSP00000414226.1
ENSG00000115368.9 ENST00000427960.5 ENSP00000400728.1
Annotation
Cancer Mutation
TCGAICGCCOSMICCGAP
IntOGen
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressTCGAICGC
COSMICTHPAHPM
DNA & RNA Element
UTRdbAREsitecircBasecircRNADb
CircNetmiRTarBasemicroRNATRANSFAC
TargetScanRepTarmiRNAMapSomamiR
miRcodeRAID2
Protein-protein Interaction
IIDiRefIndexPINAHINT
MenthaInWeb_IM
Disease-associated Variation
GWASdbGWAS Central
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
HPRDPhospho.ELMUniProtPHOSIDA
BioGRIDmUbiSiDa
DNA Methylation
TCGAICGC
Protein Expression/Proteomics
THPAHPMGPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.20e-19 71.2 55 93
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf..sd.tllvsGsdDgtikvWDlrtgvll 36
           gH + vt++++  ++   l s+s Dgtik+WD+ +g l+
   Q: 55   GHRNLVTGIQLnpNNhLQLYSCSLDGTIKLWDYIDGILI 93
           8**********95434448*************8877665 PP
   
Organism Homo sapiens
Protein Sequence
(Fasta)
MVEEENIRVV RCGGSELNFR RAVFSADSKY IFCVSGDFVK VYSTVTEECV HILHGHRNLV 60
TGIQLNPNNH LQLYSCSLDG TIKLWDYIDG ILIKTFIVGC KLHALFTLAQ AEDSVFVIVN 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Hsa-045976|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Nucleotide Sequence
(Fasta)
GGCTCAACGA AGGAAGTTCA GGGCGGGACC AGAGATTGGC CATTCCGCTA CTGCGCAAAG 60
ATGGTGGAGG AGGAGAACAT CCGCGTGGTT CGTTGTGGCG GCAGCGAGTT GAACTTTAGG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Hsa-045976|E3,WD_repeat|Homo sapiens
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0007--Acetylation
KW-0181--Complete proteome
KW-1017--Isopeptide bond
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0832--Ubl conjugation
KW-0853--WD repeat
Interpro

IPR011047--Quinoprotein_ADH-like_supfam
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0005654--C:nucleoplasm
GO:0003723--F:RNA binding
GO:1903955--P:positive regulation of protein targeting to mitochondrion
GO:1903146--P:regulation of mitophagy
GO:0006364--P:rRNA processing
KEGG hsa:84128
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-001159 Aegilops tauschii 23.55 7.00e-31 129.00
IUUC-Aml-001772 Ailuropoda melanoleuca 92.81 0.00e+00 1535.00
IUUC-Atr-003057 Amborella trichopoda 27.09 1.00e-56 214.00
IUUC-Apl-004225 Anas platyrhynchos 62.64 0.00e+00 888.00
IUUC-Aca-004528 Anolis carolinensis 63.65 0.00e+00 1073.00
IUUC-Aly-005971 Arabidopsis lyrata 25.62 8.00e-44 172.00
IUUC-Ath-006605 Arabidopsis thaliana 24.68 2.00e-43 171.00
IUUC-Ani-009273 Aspergillus nidulans 23.82 1.00e-27 118.00
IUUC-Ate-010477 Aspergillus terreus 21.83 2.00e-16 81.60
IUUC-Ame-011596 Astyanax mexicanus 54.60 0.00e+00 892.00
IUUC-Bta-013087 Bos taurus 91.58 0.00e+00 1528.00
IUUC-Bdi-014281 Brachypodium distachyon 24.76 2.00e-46 180.00
IUUC-Bol-015950 Brassica oleracea 26.17 6.00e-47 182.00
IUUC-Bra-016891 Brassica rapa 25.74 1.00e-44 175.00
IUUC-Cja-019291 Callithrix jacchus 95.56 0.00e+00 1610.00
IUUC-Cfa-020826 Canis familiaris 90.72 0.00e+00 1533.00
IUUC-Cpo-022075 Cavia porcellus 88.67 0.00e+00 1506.00
IUUC-Cre-022871 Chlamydomonas reinhardtii 48.72 1.00e-16 78.60
IUUC-Csa-023922 Chlorocebus sabaeus 98.80 0.00e+00 1651.00
IUUC-Cho-025070 Choloepus hoffmanni 89.66 0.00e+00 1417.00
IUUC-Cin-025661 Ciona intestinalis 33.77 1.00e-76 281.00
IUUC-Csv-025929 Ciona savignyi 29.28 1.00e-19 89.70
IUUC-Cgl-026473 Colletotrichum gloeosporioides 23.11 2.00e-17 84.70
IUUC-Cne-026862 Cryptococcus neoformans 25.15 7.00e-35 142.00
IUUC-Cme-027187 Cyanidioschyzon merolae 36.25 2.00e-07 52.00
IUUC-Dre-028194 Danio rerio 53.65 0.00e+00 885.00
IUUC-Dno-029393 Dasypus novemcinctus 91.31 0.00e+00 1459.00
IUUC-Dor-030476 Dipodomys ordii 83.75 0.00e+00 1363.00
IUUC-Dse-031561 Dothistroma septosporum 25.43 2.00e-14 75.50
IUUC-Dme-031625 Drosophila melanogaster 30.33 2.00e-66 247.00
IUUC-Ete-033185 Echinops telfairi 82.65 0.00e+00 1150.00
IUUC-Eca-034192 Equus caballus 93.56 0.00e+00 1494.00
IUUC-Eeu-034737 Erinaceus europaeus 81.71 4.00e-163 568.00
IUUC-Fca-036473 Felis catus 92.77 0.00e+00 1560.00
IUUC-Fal-037083 Ficedula albicollis 60.47 0.00e+00 911.00
IUUC-Fox-037801 Fusarium oxysporum 22.24 4.00e-13 70.50
IUUC-Fso-038117 Fusarium solani 23.06 8.00e-14 72.80
IUUC-Gmo-038612 Gadus morhua 52.00 0.00e+00 790.00
IUUC-Ggr-040067 Gaeumannomyces graminis 22.09 3.00e-11 64.70
IUUC-Gga-040173 Gallus gallus 62.47 5.00e-140 490.00
IUUC-Gac-042628 Gasterosteus aculeatus 50.77 0.00e+00 835.00
IUUC-Gma-043929 Glycine max 25.35 3.00e-45 177.00
IUUC-Ggo-044723 Gorilla gorilla 99.64 0.00e+00 1634.00
IUUC-Itr-048873 Ictidomys tridecemlineatus 92.17 0.00e+00 1467.00
IUUC-Lch-049534 Latimeria chalumnae 64.82 0.00e+00 1083.00
IUUC-Lpe-050961 Leersia perrieri 24.54 1.00e-42 168.00
IUUC-Loc-052545 Lepisosteus oculatus 60.29 0.00e+00 910.00
IUUC-Laf-053408 Loxodonta africana 91.34 0.00e+00 1485.00
IUUC-Mcc-055400 Macaca mulatta 98.67 0.00e+00 1651.00
IUUC-Meu-056448 Macropus eugenii 71.58 0.00e+00 699.00
IUUC-Mor-057047 Magnaporthe oryzae 32.18 4.00e-07 50.80
IUUC-Mpo-057552 Magnaporthe poae 22.48 4.00e-09 57.40
IUUC-Mtr-058588 Medicago truncatula 25.28 1.00e-39 158.00
IUUC-Mla-059102 Melampsora laricipopulina 26.18 2.00e-21 97.80
IUUC-Mga-059364 Meleagris gallopavo 61.53 0.00e+00 885.00
IUUC-Mvi-060387 Microbotryum violaceum 28.17 1.00e-37 152.00
IUUC-Mmr-061240 Microcebus murinus 92.24 0.00e+00 1533.00
IUUC-Mdo-062461 Monodelphis domestica 76.75 0.00e+00 1307.00
IUUC-Mmu-063820 Mus musculus 85.03 0.00e+00 1404.00
IUUC-Mac-064657 Musa acuminata 23.64 3.00e-37 150.00
IUUC-Mpu-066642 Mustela putorius furo 91.17 0.00e+00 1452.00
IUUC-Mlu-067113 Myotis lucifugus 80.25 0.00e+00 1341.00
IUUC-Ncr-068881 Neurospora crassa 21.58 7.00e-14 73.20
IUUC-Nle-069700 Nomascus leucogenys 99.04 0.00e+00 1654.00
IUUC-Opr-070788 Ochotona princeps 79.16 0.00e+00 1282.00
IUUC-Ont-071934 Oreochromis niloticus 53.89 0.00e+00 893.00
IUUC-Oan-073397 Ornithorhynchus anatinus 60.38 1.00e-88 319.00
IUUC-Ocu-074934 Oryctolagus cuniculus 90.96 0.00e+00 1510.00
IUUC-Oba-075556 Oryza barthii 24.85 3.00e-36 147.00
IUUC-Obr-076321 Oryza brachyantha 23.63 1.00e-42 169.00
IUUC-Ogl-077721 Oryza glaberrima 24.37 8.00e-43 169.00
IUUC-Ogu-078969 Oryza glumaepatula 24.70 2.00e-44 174.00
IUUC-Oin-079774 Oryza indica 24.37 2.00e-42 167.00
IUUC-Olo-080797 Oryza longistaminata 24.43 2.00e-19 90.90
IUUC-Ome-081288 Oryza meridionalis 24.20 1.00e-42 168.00
IUUC-Oni-082679 Oryza nivara 24.13 3.00e-42 167.00
IUUC-Opu-083382 Oryza punctata 23.69 2.00e-43 171.00
IUUC-Oru-085008 Oryza rufipogon 24.37 3.00e-43 170.00
IUUC-Osa-086286 Oryza sativa 24.25 9.00e-43 169.00
IUUC-Ola-087159 Oryzias latipes 51.48 0.00e+00 853.00
IUUC-Olu-087737 Ostreococcus lucimarinus 21.20 3.00e-33 137.00
IUUC-Oga-087932 Otolemur garnettii 91.49 0.00e+00 1547.00
IUUC-Oar-090087 Ovis aries 91.25 0.00e+00 1505.00
IUUC-Ptr-090836 Pan troglodytes 99.52 0.00e+00 1668.00
IUUC-Pan-091703 Papio anubis 96.90 0.00e+00 1594.00
IUUC-Psi-093289 Pelodiscus sinensis 67.03 0.00e+00 1109.00
IUUC-Pma-094549 Petromyzon marinus 40.48 8.00e-164 570.00
IUUC-Ppa-095363 Physcomitrella patens 24.91 1.00e-42 168.00
IUUC-Pfo-096805 Poecilia formosa 49.05 0.00e+00 790.00
IUUC-Pab-098646 Pongo abelii 99.40 0.00e+00 1657.00
IUUC-Pop-099099 Populus trichocarpa 25.92 2.00e-46 180.00
IUUC-Pca-100866 Procavia capensis 87.00 0.00e+00 1434.00
IUUC-Ppe-101421 Prunus persica 26.75 2.00e-43 170.00
IUUC-Pva-103237 Pteropus vampyrus 81.45 0.00e+00 1306.00
IUUC-Pgr-103514 Puccinia graminis 25.91 1.00e-16 82.40
IUUC-Pte-104266 Pyrenophora teres 23.41 4.00e-20 94.00
IUUC-Pyt-104657 Pyrenophora triticirepentis 22.24 1.00e-20 95.50
IUUC-Rno-105785 Rattus norvegicus 84.49 0.00e+00 1379.00
IUUC-Sha-107623 Sarcophilus harrisii 76.52 0.00e+00 1329.00
IUUC-Sja-107756 Schizosaccharomyces japonicus 22.20 3.00e-15 77.40
IUUC-Spo-108237 Schizosaccharomyces pombe 21.73 2.00e-22 101.00
IUUC-Smo-109506 Selaginella moellendorffii 24.05 2.00e-41 164.00
IUUC-Sit-110013 Setaria italica 23.69 1.00e-47 184.00
IUUC-Sly-111872 Solanum lycopersicum 24.82 1.00e-41 164.00
IUUC-Sar-113336 Sorex araneus 59.18 4.00e-134 472.00
IUUC-Sbi-114792 Sorghum bicolor 24.79 1.00e-48 188.00
IUUC-Sre-114923 Sporisorium reilianum 27.80 6.00e-53 203.00
IUUC-Ssc-115517 Sus scrofa 91.85 0.00e+00 1525.00
IUUC-Tgu-116868 Taeniopygia guttata 60.29 0.00e+00 984.00
IUUC-Tru-118503 Takifugu rubripes 51.10 0.00e+00 802.00
IUUC-Tsy-119349 Tarsius syrichta 93.37 0.00e+00 1563.00
IUUC-Tni-120437 Tetraodon nigroviridis 49.16 0.00e+00 811.00
IUUC-Tca-121127 Theobroma cacao 25.47 6.00e-44 172.00
IUUC-Tvi-122323 Trichoderma virens 22.83 4.00e-12 67.40
IUUC-Tae-123418 Triticum aestivum 23.59 1.00e-44 174.00
IUUC-Tme-127167 Tuber melanosporum 19.52 1.00e-19 92.80
IUUC-Tbe-127376 Tupaia belangeri 89.14 0.00e+00 653.00
IUUC-Ttr-128949 Tursiops truncatus 87.73 0.00e+00 1480.00
IUUC-Uma-129522 Ustilago maydis 27.72 9.00e-52 199.00
IUUC-Vda-129794 Verticillium dahliae 35.14 5.00e-05 43.90
IUUC-Vpa-130282 Vicugna pacos 92.36 0.00e+00 1367.00
IUUC-Xtr-132078 Xenopus tropicalis 51.12 0.00e+00 837.00
IUUC-Xma-133958 Xiphophorus maculatus 47.36 0.00e+00 778.00
IUUC-Zma-135807 Zea mays 23.92 3.00e-45 177.00
Created Date 25-Jun-2017

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