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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Ath-006763
Ensembl Protein ID AT3G54610.1
UniProt Accession Q9AR19; O22654; Q7G1G9; Q9M1G7; GCN5_ARATH
Genbank Protein ID AAB92257.1; AAB87070.1; AAK31318.1; AAK31321.1; CAB77581.1; AEE79255.1; AAP68348.1; AAN72068.1
Protein Name Histone acetyltransferase GCN5; BIG TOP protein
Genbank Nucleotide ID AF037442; AF031958; AF338768; AF338771; AL138656; CP002686; BT008909; BT002057
Gene Name HAG1; BGT; GCN5; HAT1; At3g54610; T14E10.180
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT3G54610 AT3G54610.1 AT3G54610.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
Protein-protein Interaction
iRefIndexPINAHINTMentha
Post-translational Modifications (PTMs)
dbPPTdbPTM
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
E3 activity/Other 43.51 3.00e-75 280.00 IUUC-Hsa-046970
Active Site
Position(s) Description Evidence
289 Proton donor/acceptor {ECO:0000250|UniProtKB:Q92830}
Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description


     Acetylates histone H3 and ADA2 proteins in vitro. Acetylates 'Lys-14' of histone H3. Acetylation of histones gives a specific tag for epigenetic transcription activation. Operates in concert with certain DNA-binding transcriptional activators. Acts via the formation of large multiprotein complexes that modify the chromatin (By similarity).
 Acetylates histone H3 and ADA2 proteins in vitro. Acetylates 'Lys-14' of histone H3. Acetylation of histones gives a specific tag for epigenetic transcription activation. Operates in concert with certain DNA-binding transcriptional activators. Acts via the formation of large multiprotein complexes that modify the chromatin (By similarity).
Protein Sequence
(Fasta)
MDSHSSHLNA ANRSRSSQTP SPSHSASASV TSSLHKRKLA ATTAANAAAS EDHAPPSSSF 60
PPSSFSADTR DGALTSNDEL ESISARGADT DSDPDESEDI VVDDDEDEFA PEQDQDSSIR 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Ath-006763|E3,E3 activity/Other|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGAATTACA ATTACCGAAT TAGTTTCGGT TTAAAATTTG TTGGATCAAT AAAACAAAAA 60
AAAAAAAACG ATGCCAGAAT ATTCCGTTCG TCGGCGTAGT CTTTCCCGCC CCCAAATTAT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Ath-006763|E3,E3 activity/Other|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0010--Activator
KW-0012--Acyltransferase
KW-0103--Bromodomain
KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0808--Transferase
Interpro

IPR016181--Acyl_CoA_acyltransferase
IPR001487--Bromodomain
IPR018359--Bromodomain_CS
IPR000182--GNAT_dom
PROSITE

PS00633--BROMODOMAIN_1
PS50014--BROMODOMAIN_2
PS51186--GNAT
Pfam

PF00583--Acetyltransf_1
PF00439--Bromodomain
PRINTS

PR00503--BROMODOMAIN
SMART

SM00297--BROMO
Gene Ontology

GO:0000123--C:histone acetyltransferase complex
GO:0005634--C:nucleus
GO:0016407--F:acetyltransferase activity
GO:0003677--F:DNA binding
GO:0010484--F:H3 histone acetyltransferase activity
GO:0004402--F:histone acetyltransferase activity
GO:0009908--P:flower development
GO:0016573--P:histone acetylation
GO:0045893--P:positive regulation of transcription, DNA-templated
GO:0010321--P:regulation of vegetative phase change
GO:0009416--P:response to light stimulus
GO:0010015--P:root morphogenesis
GO:0006351--P:transcription, DNA-templated
KEGG ath:AT3G54610
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Aml-001599 Ailuropoda melanoleuca 42.64 6.00e-77 281.00
IUUC-Atr-003130 Amborella trichopoda 74.68 0.00e+00 634.00
IUUC-Apl-004026 Anas platyrhynchos 43.84 9.00e-80 290.00
IUUC-Aca-005148 Anolis carolinensis 44.68 3.00e-22 100.00
IUUC-Aly-006486 Arabidopsis lyrata 98.59 0.00e+00 927.00
IUUC-Ago-007819 Ashbya gossypii 46.13 2.00e-91 328.00
IUUC-Acl-008194 Aspergillus clavatus 42.98 4.00e-83 301.00
IUUC-Afl-008546 Aspergillus flavus 42.41 2.00e-83 301.00
IUUC-Afu-009124 Aspergillus fumigatus 43.55 3.00e-84 304.00
IUUC-Ani-009432 Aspergillus nidulans 43.32 6.00e-81 293.00
IUUC-Ang-009824 Aspergillus niger 43.27 8.00e-83 300.00
IUUC-Aor-010076 Aspergillus oryzae 41.57 1.00e-80 292.00
IUUC-Ame-011093 Astyanax mexicanus 45.83 1.00e-23 106.00
IUUC-Bgr-012003 Blumeria graminis 42.37 7.00e-79 286.00
IUUC-Bta-012381 Bos taurus 44.74 1.00e-81 297.00
IUUC-Bci-013974 Botrytis cinerea 42.21 7.00e-81 293.00
IUUC-Bdi-015016 Brachypodium distachyon 74.87 1.00e-178 619.00
IUUC-Cel-018633 Caenorhabditis elegans 34.99 5.00e-60 225.00
IUUC-Cja-019375 Callithrix jacchus 42.64 6.00e-77 281.00
IUUC-Cfa-020400 Canis familiaris 42.64 7.00e-77 281.00
IUUC-Cpo-021686 Cavia porcellus 44.14 3.00e-80 292.00
IUUC-Cre-023019 Chlamydomonas reinhardtii 47.93 4.00e-106 377.00
IUUC-Csa-024252 Chlorocebus sabaeus 44.14 3.00e-80 292.00
IUUC-Cho-024635 Choloepus hoffmanni 57.27 6.00e-34 138.00
IUUC-Cin-025450 Ciona intestinalis 36.52 5.00e-18 84.70
IUUC-Csv-026235 Ciona savignyi 37.00 8.00e-18 82.80
IUUC-Cgl-026660 Colletotrichum gloeosporioides 42.21 2.00e-79 288.00
IUUC-Cne-027050 Cryptococcus neoformans 40.33 2.00e-64 239.00
IUUC-Dre-027468 Danio rerio 43.24 8.00e-80 291.00
IUUC-Dno-029306 Dasypus novemcinctus 43.84 8.00e-80 290.00
IUUC-Dor-030465 Dipodomys ordii 33.00 5.00e-45 175.00
IUUC-Dse-031386 Dothistroma septosporum 41.37 4.00e-77 281.00
IUUC-Dme-032140 Drosophila melanogaster 45.26 9.00e-23 103.00
IUUC-Ete-032789 Echinops telfairi 45.83 1.00e-22 103.00
IUUC-Eca-034212 Equus caballus 42.64 9.00e-77 280.00
IUUC-Eeu-034605 Erinaceus europaeus 35.54 9.00e-51 194.00
IUUC-Fca-035972 Felis catus 44.14 3.00e-80 292.00
IUUC-Fal-037223 Ficedula albicollis 43.54 4.00e-80 291.00
IUUC-Fox-037874 Fusarium oxysporum 42.78 8.00e-81 293.00
IUUC-Fso-038286 Fusarium solani 43.06 2.00e-80 291.00
IUUC-Gmo-039102 Gadus morhua 43.90 3.00e-79 289.00
IUUC-Ggr-039925 Gaeumannomyces graminis 40.56 6.00e-81 293.00
IUUC-Gga-041181 Gallus gallus 43.84 3.00e-80 292.00
IUUC-Gac-041887 Gasterosteus aculeatus 43.03 1.00e-78 286.00
IUUC-Gma-043540 Glycine max 70.65 0.00e+00 715.00
IUUC-Ggo-044607 Gorilla gorilla 44.14 2.00e-80 293.00
IUUC-Hsa-046970 Homo sapiens 44.14 2.00e-80 293.00
IUUC-Hvu-047105 Hordeum vulgare 78.54 2.00e-99 354.00
IUUC-Itr-048740 Ictidomys tridecemlineatus 45.83 4.00e-23 104.00
IUUC-Kpa-049146 Komagataella pastoris 42.93 1.00e-86 313.00
IUUC-Lch-049478 Latimeria chalumnae 43.84 7.00e-80 291.00
IUUC-Lpe-051678 Leersia perrieri 66.59 5.00e-160 556.00
IUUC-Loc-052255 Lepisosteus oculatus 40.90 5.00e-83 301.00
IUUC-Laf-054575 Loxodonta africana 42.64 9.00e-77 281.00
IUUC-Mcc-055161 Macaca mulatta 44.14 2.00e-80 293.00
IUUC-Mor-057026 Magnaporthe oryzae 40.40 1.00e-78 286.00
IUUC-Mpo-057590 Magnaporthe poae 40.68 1.00e-79 289.00
IUUC-Mtr-057835 Medicago truncatula 68.17 1.00e-157 548.00
IUUC-Mla-058950 Melampsora laricipopulina 42.45 2.00e-74 272.00
IUUC-Mga-060204 Meleagris gallopavo 44.79 2.00e-22 102.00
IUUC-Mvi-060295 Microbotryum violaceum 43.90 3.00e-86 312.00
IUUC-Mmr-060643 Microcebus murinus 42.94 4.00e-76 278.00
IUUC-Mdo-062732 Monodelphis domestica 43.24 7.00e-79 288.00
IUUC-Mmu-064125 Mus musculus 42.34 8.00e-77 281.00
IUUC-Mpu-066371 Mustela putorius furo 44.14 3.00e-80 291.00
IUUC-Mlu-067447 Myotis lucifugus 44.44 4.00e-79 288.00
IUUC-Nfi-068373 Neosartorya fischeri 43.27 8.00e-85 306.00
IUUC-Ncr-068652 Neurospora crassa 42.62 3.00e-80 291.00
IUUC-Nle-069659 Nomascus leucogenys 44.14 2.00e-80 293.00
IUUC-Ont-071244 Oreochromis niloticus 43.54 1.00e-80 293.00
IUUC-Oan-072794 Ornithorhynchus anatinus 43.54 7.00e-79 287.00
IUUC-Ocu-074701 Oryctolagus cuniculus 42.64 2.00e-76 280.00
IUUC-Oba-075479 Oryza barthii 66.38 9.00e-134 469.00
IUUC-Ogl-076970 Oryza glaberrima 68.62 1.00e-169 588.00
IUUC-Oin-079610 Oryza indica 66.38 1.00e-133 469.00
IUUC-Oni-083016 Oryza nivara 67.86 6.00e-168 583.00
IUUC-Opu-083976 Oryza punctata 75.81 2.00e-164 571.00
IUUC-Osa-085814 Oryza sativa 68.62 1.00e-169 588.00
IUUC-Ola-087071 Oryzias latipes 43.54 2.00e-80 293.00
IUUC-Olu-087711 Ostreococcus lucimarinus 50.00 8.00e-115 406.00
IUUC-Oga-089043 Otolemur garnettii 42.64 6.00e-77 281.00
IUUC-Oar-089893 Ovis aries 43.84 4.00e-81 295.00
IUUC-Ptr-090629 Pan troglodytes 44.14 2.00e-80 293.00
IUUC-Pan-092305 Papio anubis 43.88 7.00e-79 288.00
IUUC-Psi-093574 Pelodiscus sinensis 42.81 6.00e-75 274.00
IUUC-Pma-094160 Petromyzon marinus 42.86 4.00e-80 291.00
IUUC-Ppa-095410 Physcomitrella patens 62.47 8.00e-160 556.00
IUUC-Pfo-097043 Poecilia formosa 43.54 1.00e-80 293.00
IUUC-Pab-098748 Pongo abelii 44.14 7.00e-80 291.00
IUUC-Pca-100223 Procavia capensis 44.14 1.00e-79 290.00
IUUC-Ppe-101832 Prunus persica 72.89 0.00e+00 721.00
IUUC-Pva-102122 Pteropus vampyrus 41.74 4.00e-76 278.00
IUUC-Pte-104228 Pyrenophora teres 42.69 4.00e-82 297.00
IUUC-Pyt-104702 Pyrenophora triticirepentis 42.69 7.00e-82 296.00
IUUC-Rno-105749 Rattus norvegicus 44.79 9.00e-23 103.00
IUUC-Sce-106432 Saccharomyces cerevisiae 47.27 2.00e-94 338.00
IUUC-Sha-107338 Sarcophilus harrisii 43.54 9.00e-79 287.00
IUUC-Spo-108273 Schizosaccharomyces pombe 43.84 1.00e-89 322.00
IUUC-Ssl-108545 Sclerotinia sclerotiorum 40.79 4.00e-75 274.00
IUUC-Smo-109385 Selaginella moellendorffii 67.90 5.00e-154 536.00
IUUC-Sit-110222 Setaria italica 74.55 5.00e-168 583.00
IUUC-Sly-111498 Solanum lycopersicum 68.07 1.00e-134 471.00
IUUC-Sar-113574 Sorex araneus 42.64 2.00e-76 279.00
IUUC-Sbi-114471 Sorghum bicolor 74.29 5.00e-167 580.00
IUUC-Sre-114915 Sporisorium reilianum 41.30 2.00e-87 316.00
IUUC-Ssc-116097 Sus scrofa 42.64 1.00e-76 280.00
IUUC-Tgu-116699 Taeniopygia guttata 43.84 3.00e-80 292.00
IUUC-Tru-118001 Takifugu rubripes 44.31 2.00e-79 290.00
IUUC-Tsy-118910 Tarsius syrichta 38.74 9.00e-62 231.00
IUUC-Tni-119684 Tetraodon nigroviridis 43.24 4.00e-79 288.00
IUUC-Tca-121066 Theobroma cacao 72.58 0.00e+00 721.00
IUUC-Tre-122112 Trichoderma reesei 43.06 2.00e-81 295.00
IUUC-Tvi-122355 Trichoderma virens 43.06 3.00e-81 294.00
IUUC-Tae-123931 Triticum aestivum 73.51 3.00e-167 581.00
IUUC-Tur-126587 Triticum urartu 72.75 2.00e-165 574.00
IUUC-Tme-126963 Tuber melanosporum 41.62 5.00e-83 300.00
IUUC-Tbe-127304 Tupaia belangeri 39.34 1.00e-63 236.00
IUUC-Ttr-128536 Tursiops truncatus 42.34 4.00e-76 278.00
IUUC-Uma-129538 Ustilago maydis 42.09 5.00e-87 314.00
IUUC-Vda-129860 Verticillium dahliae 42.57 2.00e-82 298.00
IUUC-Vpa-130239 Vicugna pacos 51.49 5.00e-38 152.00
IUUC-Vvi-130897 Vitis vinifera 66.14 0.00e+00 708.00
IUUC-Xtr-132300 Xenopus tropicalis 43.54 3.00e-79 289.00
IUUC-Xma-134105 Xiphophorus maculatus 42.77 8.00e-78 284.00
IUUC-Yli-134345 Yarrowia lipolytica 43.65 1.00e-88 319.00
IUUC-Zma-135384 Zea mays 73.54 9.00e-164 569.00
Created Date 25-Jun-2017

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