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Basic Information Integrated Annotations

Tag Content
iUUCD ID IUUC-Ath-007370
Ensembl Protein ID AT1G04240.2
UniProt Accession Q38822; O04741; IAA3_ARATH
Genbank Protein ID AAC49045.1; AAB70452.1; AEE27673.1; AAG48757.1; AAL36363.1
Protein Name Auxin-responsive protein IAA3; Indoleacetic acid-induced protein 3; Short hypocotyl; Suppressor of HY2
Genbank Nucleotide ID U18406; AC000104; CP002684; AF332393; AY064007
Gene Name IAA3; SHY2; At1g04240; F19P19.32
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
AT1G04240 AT1G04240.2 AT1G04240.2
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpress
DNA & RNA Element
TRANSFAC
Protein-protein Interaction
iRefIndexPINAHINTMentha
Post-translational Modifications (PTMs)
dbPPT
Protein Expression/Proteomics
Status Unreviewed
Classification
Family E-Value Score Start End
ULD/UDP/UFD/PB1 2.70e-17 63.6 193 278
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   ULD/UDP/UFD/PB1

   S: 2    vrvkvsykgeirsfaldlekpgkfedLlkavrt.lt..........elknsevalkYeDedGDlvtlksDedldkavsllaskksllrlliqk 83
    + vkvs++g+++++++dl+ + ++++Llka++ ++ ++k+s++ ++YeD+dGD++ l +D+++++++ ++rl+i+k
   Q: 193 IYVKVSMDGAPYLRKIDLSCYKGYSELLKALEVmFKfsvgeyferdGYKGSDFVPTYEDKDGDWM-LIGDVPWEMFIC------TCKRLRIMK 278
    78*******************************6448899999999*******************.************......9******98 PP
   

Organism Arabidopsis thaliana
Functional Description
(View)

Functional Description



     Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Plays a central role in auxin regulation of root growth, in gravitropism, and in lateral root formation (PubMed:9895319). Regulated by an auxin-induced protein turnover (PubMed:14617065). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. When activated by cytokinin, restricts the expression of the PIN genes to the vascular transition zone (PubMed:19039136). Induction of SHY2 in the vascular transition zone restricts BRX expression to down-regulate PIN3 and thus limit meristem growth, but proper SHY2 expression requires BRX (PubMed:21149702). Involved in meristem growth and in determining its size (PubMed:20605455). May participate in strigolactone signaling to regulate meristem size and lateral root formation (PubMed:23425316).
Aux/IAA proteins are short-lived transcriptional factors that function as repressors of early auxin response genes at low auxin concentrations. Repression is thought to result from the interaction with auxin response factors (ARFs), proteins that bind to the auxin-responsive promoter element (AuxRE). Plays a central role in auxin regulation of root growth, in gravitropism, and in lateral root formation (PubMed:9895319). Regulated by an auxin-induced protein turnover (PubMed:14617065). Formation of heterodimers with ARF proteins may alter their ability to modulate early auxin response genes expression. When activated by cytokinin, restricts the expression of the PIN genes to the vascular transition zone (PubMed:19039136). Induction of SHY2 in the vascular transition zone restricts BRX expression to down-regulate PIN3 and thus limit meristem growth, but proper SHY2 expression requires BRX (PubMed:21149702). Involved in meristem growth and in determining its size (PubMed:20605455). May participate in strigolactone signaling to regulate meristem size and lateral root formation (PubMed:23425316).
Protein Sequence
(Fasta)
MGEKESVPTN VPKKMGHTFA SKLLLLLPTS LAFFPLSLIQ KTVSSLSTSI YLYSPLTCIK 60
HSASSKPLIF IISSFSISLL SFKDNNQKLF FLSSPAILEE MDEFVNLKET ELRLGLPGTD 120
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Protein Fasta Sequence



>IUUC-Ath-007370|ULD,PB1|Arabidopsis thaliana
Please wait for a moment...
Nucleotide Sequence
(Fasta)
CGAAGATTTG ATCTGGACCG TCTATCACAA GAAAGAAAGA TGAAAATATT TTGTTTTTGG 60
GTTTGGACAG ATGGGAGAAA AAGAAAGTGT CCCCACAAAT GTCCCCAAGA AGATGGGACA 120
It may take some time, please wait.

Nucleotide Fasta Sequence



>IUUC-Ath-007370|ULD,PB1|Arabidopsis thaliana
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0927--Auxin signaling pathway
KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation

Interpro

IPR033389--AUX/IAA_dom
IPR003311--AUX_IAA
IPR000270--PB1_dom

PROSITE

PS51745--PB1

Pfam

PF02309--AUX_IAA

Gene Ontology

GO:0005634--C:nucleus
GO:0003700--F:transcription factor activity, sequence-specific DNA binding
GO:0044212--F:transcription regulatory region DNA binding
GO:0009734--P:auxin-activated signaling pathway
GO:0009733--P:response to auxin
GO:0006351--P:transcription, DNA-templated

KEGG ath:AT1G04240
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000969 Aegilops tauschii 45.15 9.00e-37 145.00
IUUC-Aly-005805 Arabidopsis lyrata 94.21 3.00e-95 340.00
IUUC-Bdi-014020 Brachypodium distachyon 48.51 4.00e-39 153.00
IUUC-Bol-015408 Brassica oleracea 83.16 8.00e-91 325.00
IUUC-Bra-016684 Brassica rapa 84.74 9.00e-92 328.00
IUUC-Hvu-047853 Hordeum vulgare 46.83 8.00e-43 166.00
IUUC-Mac-064820 Musa acuminata 55.38 9.00e-55 205.00
IUUC-Ncr-068890 Neurospora crassa 37.74 2.10e-01 29.30
IUUC-Oba-075141 Oryza barthii 51.00 1.00e-46 178.00
IUUC-Obr-076144 Oryza brachyantha 48.53 3.00e-40 157.00
IUUC-Ogu-078093 Oryza glumaepatula 49.50 1.00e-45 175.00
IUUC-Oin-079780 Oryza indica 49.50 2.00e-44 171.00
IUUC-Oni-083078 Oryza nivara 49.50 2.00e-44 171.00
IUUC-Oru-084991 Oryza rufipogon 49.50 2.00e-44 171.00
IUUC-Osa-085321 Oryza sativa 49.50 2.00e-44 171.00
IUUC-Pab-098295 Pongo abelii 40.00 3.90e-01 27.30
IUUC-Ppe-101322 Prunus persica 65.61 1.00e-70 258.00
IUUC-Sit-109772 Setaria italica 50.81 3.00e-44 171.00
Created Date 25-Jun-2017

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