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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Mmu-063616
UUCD1 version UUC-MuM-00828
Ensembl Protein ID ENSMUSP00000113014.1
UniProt Accession Q91VU6; Q3U836; Q8JZV8; DCA11_MOUSE
Genbank Protein ID BAC28348.1; BAE31183.1; AAH08545.1; AAH37001.1
Protein Name DDB1- and CUL4-associated factor 11; WD repeat-containing protein 23
Genbank Nucleotide ID AK033540; AK152395; BC008545; BC037001
Gene Name Dcaf11; D14Ucla1; Wdr23
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000022214.14 ENSMUST00000117236.7 ENSMUSP00000113014.1
ENSMUSG00000022214.14 ENSMUST00000150019.7 ENSMUSP00000117617.1
ENSMUSG00000022214.14 ENSMUST00000117701.7 ENSMUSP00000113620.1
ENSMUSG00000022214.14 ENSMUST00000143375.7 ENSMUSP00000121570.1
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarRAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
Phospho.ELMUniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.20e-25 88.8 482 514
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 2    Htdsvtclaf..sdtllvsGsdDgtikvWDlrt 32
           H++ v+++++   +  +vs+s+Dg++++W +r+
   Q: 482  HKACVRDVSWhpFEEKIVSSSWDGNLRLWQYRQ 514
           9999******965599*************9775 PP
   
Organism Mus musculus
Functional Description
(View)

Functional Description


     May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
 May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex.
Protein Sequence
(Fasta)
MGSRNSSSAG SGSLEPSEGL SRRGTGLRRS EEEEEEDEDV DLAQVLAYLL RRGQVRLVQG 60
RGAANLQLIQ ALSDSEEEHD SAWDGRLGDR YNPPVDATPD TRELEYNEIK TQVGLATGRL 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063616|E3,WD_repeat|Mus musculus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
AGGGGCGCGT GCGCACTAAG GCAACCGGAA AGGCTCCGGG GACGGCCGCG GCACTTAGGG 60
AGCGTATGCA AAGACCAAGA AAGGAAGCCA GGGGTCGTCA GACAAGACCC CCGCTGGTAA 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063616|E3,WD_repeat|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0025--Alternative splicing
KW-0181--Complete proteome
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0833--Ubl conjugation pathway
KW-0853--WD repeat
Interpro

IPR017399--DCAF11/LEC14B
IPR020472--G-protein_beta_WD-40_rep
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom
PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0080008--C:Cul4-RING E3 ubiquitin ligase complex
GO:0005654--C:nucleoplasm
GO:0016567--P:protein ubiquitination
KEGG mmu:28199
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000659 Aegilops tauschii 42.01 4.00e-65 242.00
IUUC-Aml-001732 Ailuropoda melanoleuca 95.59 0.00e+00 982.00
IUUC-Atr-002856 Amborella trichopoda 40.58 8.00e-80 290.00
IUUC-Aca-005081 Anolis carolinensis 81.37 0.00e+00 827.00
IUUC-Aly-006571 Arabidopsis lyrata 43.28 2.00e-89 323.00
IUUC-Ath-007313 Arabidopsis thaliana 43.78 2.00e-90 326.00
IUUC-Acl-008126 Aspergillus clavatus 33.81 8.00e-59 221.00
IUUC-Afl-008513 Aspergillus flavus 34.88 3.00e-60 226.00
IUUC-Afu-008765 Aspergillus fumigatus 34.76 3.00e-57 216.00
IUUC-Ani-009456 Aspergillus nidulans 36.80 4.00e-63 236.00
IUUC-Ang-009781 Aspergillus niger 33.16 2.00e-52 200.00
IUUC-Aor-010093 Aspergillus oryzae 34.88 3.00e-60 226.00
IUUC-Ate-010456 Aspergillus terreus 35.45 2.00e-60 227.00
IUUC-Ame-011825 Astyanax mexicanus 70.37 8.00e-176 609.00
IUUC-Bgr-012310 Blumeria graminis 33.97 8.00e-57 214.00
IUUC-Bta-013043 Bos taurus 93.44 0.00e+00 978.00
IUUC-Bci-013758 Botrytis cinerea 36.10 3.00e-59 223.00
IUUC-Bdi-014294 Brachypodium distachyon 43.67 3.00e-87 315.00
IUUC-Bol-016186 Brassica oleracea 44.05 9.00e-85 308.00
IUUC-Bra-018035 Brassica rapa 44.05 8.00e-85 307.00
IUUC-Cel-018145 Caenorhabditis elegans 42.59 2.00e-86 313.00
IUUC-Cja-018940 Callithrix jacchus 92.90 0.00e+00 951.00
IUUC-Cfa-020064 Canis familiaris 95.79 0.00e+00 983.00
IUUC-Cpo-022220 Cavia porcellus 92.26 0.00e+00 966.00
IUUC-Cre-022728 Chlamydomonas reinhardtii 50.00 1.00e-64 239.00
IUUC-Csa-023158 Chlorocebus sabaeus 93.49 0.00e+00 952.00
IUUC-Cho-024797 Choloepus hoffmanni 74.58 1.00e-92 333.00
IUUC-Cgl-026444 Colletotrichum gloeosporioides 36.78 2.00e-62 234.00
IUUC-Cne-026917 Cryptococcus neoformans 36.16 4.00e-49 189.00
IUUC-Cme-027273 Cyanidioschyzon merolae 28.73 1.00e-44 175.00
IUUC-Dre-028711 Danio rerio 66.86 0.00e+00 725.00
IUUC-Dno-029851 Dasypus novemcinctus 93.40 0.00e+00 946.00
IUUC-Dor-030952 Dipodomys ordii 86.78 0.00e+00 832.00
IUUC-Dse-031288 Dothistroma septosporum 32.22 3.00e-56 213.00
IUUC-Dme-031925 Drosophila melanogaster 37.13 6.00e-80 291.00
IUUC-Ete-032983 Echinops telfairi 87.45 0.00e+00 844.00
IUUC-Eca-033499 Equus caballus 94.17 0.00e+00 1013.00
IUUC-Eeu-035179 Erinaceus europaeus 90.58 0.00e+00 770.00
IUUC-Fca-035615 Felis catus 96.17 0.00e+00 969.00
IUUC-Fox-037867 Fusarium oxysporum 37.64 1.00e-56 214.00
IUUC-Fso-038274 Fusarium solani 36.29 3.00e-57 216.00
IUUC-Gmo-038731 Gadus morhua 69.23 0.00e+00 722.00
IUUC-Ggr-039861 Gaeumannomyces graminis 33.48 5.00e-57 215.00
IUUC-Gac-041615 Gasterosteus aculeatus 69.71 0.00e+00 720.00
IUUC-Gma-043167 Glycine max 42.75 3.00e-89 322.00
IUUC-Hsa-046061 Homo sapiens 93.40 0.00e+00 974.00
IUUC-Hvu-047177 Hordeum vulgare 56.16 1.00e-61 229.00
IUUC-Itr-048985 Ictidomys tridecemlineatus 93.49 0.00e+00 953.00
IUUC-Lch-050257 Latimeria chalumnae 57.96 2.00e-156 545.00
IUUC-Lpe-051521 Leersia perrieri 44.51 1.00e-84 306.00
IUUC-Lma-053067 Leptosphaeria maculans 35.73 9.00e-53 201.00
IUUC-Laf-054259 Loxodonta africana 95.46 0.00e+00 954.00
IUUC-Mcc-054958 Macaca mulatta 93.68 0.00e+00 927.00
IUUC-Meu-056889 Macropus eugenii 85.21 0.00e+00 863.00
IUUC-Mor-057196 Magnaporthe oryzae 35.66 4.00e-57 216.00
IUUC-Mpo-057340 Magnaporthe poae 30.96 3.00e-54 206.00
IUUC-Mtr-058464 Medicago truncatula 42.96 8.00e-90 324.00
IUUC-Mla-058873 Melampsora laricipopulina 29.98 4.00e-50 192.00
IUUC-Mvi-060439 Microbotryum violaceum 34.95 3.00e-63 236.00
IUUC-Mmr-061329 Microcebus murinus 91.25 0.00e+00 952.00
IUUC-Mdo-062123 Monodelphis domestica 81.57 0.00e+00 846.00
IUUC-Mac-064473 Musa acuminata 42.54 6.00e-81 295.00
IUUC-Mpu-066351 Mustela putorius furo 94.88 0.00e+00 865.00
IUUC-Mlu-067043 Myotis lucifugus 96.45 0.00e+00 940.00
IUUC-Nfi-068552 Neosartorya fischeri 32.85 3.00e-57 216.00
IUUC-Ncr-068715 Neurospora crassa 36.68 5.00e-57 215.00
IUUC-Nle-070052 Nomascus leucogenys 93.57 0.00e+00 971.00
IUUC-Opr-070605 Ochotona princeps 81.87 0.00e+00 869.00
IUUC-Ont-072411 Oreochromis niloticus 70.59 0.00e+00 709.00
IUUC-Ocu-074078 Oryctolagus cuniculus 95.30 0.00e+00 935.00
IUUC-Oba-075609 Oryza barthii 42.39 1.00e-85 310.00
IUUC-Obr-076556 Oryza brachyantha 43.82 2.00e-83 303.00
IUUC-Ogl-077227 Oryza glaberrima 44.51 1.00e-83 303.00
IUUC-Ogu-078264 Oryza glumaepatula 41.79 2.00e-79 290.00
IUUC-Oin-079655 Oryza indica 44.51 6.00e-84 304.00
IUUC-Olo-080362 Oryza longistaminata 40.51 1.00e-72 267.00
IUUC-Ome-081712 Oryza meridionalis 44.48 6.00e-84 304.00
IUUC-Oni-083108 Oryza nivara 44.51 6.00e-84 304.00
IUUC-Opu-084069 Oryza punctata 42.39 3.00e-85 308.00
IUUC-Oru-085209 Oryza rufipogon 42.39 1.00e-85 310.00
IUUC-Osa-086287 Oryza sativa 42.13 1.00e-84 306.00
IUUC-Ola-086329 Oryzias latipes 69.57 0.00e+00 720.00
IUUC-Oga-088779 Otolemur garnettii 93.49 0.00e+00 956.00
IUUC-Oar-089262 Ovis aries 93.44 0.00e+00 979.00
IUUC-Ptr-091346 Pan troglodytes 88.87 0.00e+00 942.00
IUUC-Pan-092716 Papio anubis 93.69 0.00e+00 954.00
IUUC-Pma-094148 Petromyzon marinus 72.32 3.00e-127 447.00
IUUC-Pno-095116 Phaeosphaeria nodorum 32.24 5.00e-53 202.00
IUUC-Ppa-095260 Physcomitrella patens 44.56 2.00e-92 332.00
IUUC-Pfo-096424 Poecilia formosa 68.44 0.00e+00 718.00
IUUC-Pab-098091 Pongo abelii 88.87 0.00e+00 912.00
IUUC-Pop-099095 Populus trichocarpa 41.83 4.00e-87 315.00
IUUC-Pca-100153 Procavia capensis 94.86 0.00e+00 937.00
IUUC-Ppe-102075 Prunus persica 42.61 1.00e-87 317.00
IUUC-Pva-102598 Pteropus vampyrus 91.26 0.00e+00 968.00
IUUC-Pgr-103327 Puccinia graminis 33.69 2.00e-52 200.00
IUUC-Ptt-103861 Puccinia triticina 26.35 4.00e-27 115.00
IUUC-Pte-104286 Pyrenophora teres 35.12 5.00e-61 229.00
IUUC-Pyt-104745 Pyrenophora triticirepentis 37.99 9.00e-52 198.00
IUUC-Rno-104890 Rattus norvegicus 97.24 0.00e+00 998.00
IUUC-Sha-106540 Sarcophilus harrisii 84.02 0.00e+00 855.00
IUUC-Ssl-108528 Sclerotinia sclerotiorum 32.84 2.00e-48 187.00
IUUC-Smo-109019 Selaginella moellendorffii 41.33 3.00e-83 301.00
IUUC-Sit-110726 Setaria italica 43.65 9.00e-89 320.00
IUUC-Sly-110856 Solanum lycopersicum 42.93 1.00e-91 330.00
IUUC-Stu-112589 Solanum tuberosum 41.77 3.00e-81 295.00
IUUC-Sar-113742 Sorex araneus 95.07 0.00e+00 952.00
IUUC-Sbi-114505 Sorghum bicolor 44.37 2.00e-70 259.00
IUUC-Sre-115073 Sporisorium reilianum 37.33 8.00e-55 208.00
IUUC-Ssc-116019 Sus scrofa 91.26 0.00e+00 965.00
IUUC-Tru-118536 Takifugu rubripes 67.62 0.00e+00 721.00
IUUC-Tsy-119518 Tarsius syrichta 93.36 0.00e+00 964.00
IUUC-Tni-120264 Tetraodon nigroviridis 69.43 0.00e+00 709.00
IUUC-Tca-121554 Theobroma cacao 42.39 1.00e-86 313.00
IUUC-Tre-122144 Trichoderma reesei 35.90 7.00e-57 214.00
IUUC-Tvi-122472 Trichoderma virens 36.07 1.00e-58 221.00
IUUC-Tae-124083 Triticum aestivum 46.11 8.00e-84 304.00
IUUC-Tur-126714 Triticum urartu 37.84 7.00e-74 271.00
IUUC-Tme-127050 Tuber melanosporum 34.20 1.00e-68 254.00
IUUC-Tbe-127495 Tupaia belangeri 94.87 0.00e+00 965.00
IUUC-Ttr-128553 Tursiops truncatus 94.17 0.00e+00 996.00
IUUC-Uma-129557 Ustilago maydis 37.60 5.00e-55 209.00
IUUC-Vda-129951 Verticillium dahliae 35.39 1.00e-59 224.00
IUUC-Vpa-130542 Vicugna pacos 84.45 1.00e-103 370.00
IUUC-Vvi-131266 Vitis vinifera 43.62 4.00e-89 322.00
IUUC-Xtr-132525 Xenopus tropicalis 71.46 0.00e+00 721.00
IUUC-Xma-133165 Xiphophorus maculatus 68.62 0.00e+00 721.00
IUUC-Yli-134635 Yarrowia lipolytica 25.88 6.00e-21 96.30
IUUC-Zma-135874 Zea mays 43.00 3.00e-86 311.00
Created Date 25-Jun-2017

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