iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Post-translational Modifications (PTMs)
CPLM	dbPAF	dbPTM	UniProt
BioGRID
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-07	29.4	188	226

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..........sdtllvsGsdDgtikvWDl 30
           Ht +vt+++           +dt l + s D ti+++Dl
   Q: 188  HTLPVTDFQVsssqgkflscTDTKLFTVSQDATIRCYDL 226
           666666666666666668766799**************7 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA.

Protein Sequence
(Fasta)

MDEQVIFTTN TSGTIASVHS FEQINLRQCS TQSRNSCVQV GNKYLFIAQA QKALINVYNL 60
SGSFKRESVE QRLPLPEILK CLEVVENDGV QYDRIQGVNH NLPDFNLPYL LLGSTESGKL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGATGAGC AAGTTATTTT TACAACAAAT ACCTCAGGAA CAATAGCTTC TGTACACTCA 60
TTTGAACAGA TAAATTTGAG GCAATGCTCC ACTCAATCAA GAAATAGCTG TGTTCAAGTA 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0677--Repeat
KW-0690--Ribosome biogenesis
KW-0698--rRNA processing
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR017986--WD40_repeat_dom

PROSITE

PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

SMART

SM00320--WD40

Gene Ontology

GO:0005656--C:nuclear pre-replicative complex
GO:0005654--C:nucleoplasm
GO:0097344--C:Rix1 complex
GO:0003682--F:chromatin binding
GO:0006267--P:pre-replicative complex assembly involved in nuclear cell cycle DNA replication
GO:0030174--P:regulation of DNA-dependent DNA replication initiation
GO:0000027--P:ribosomal large subunit assembly
GO:0006364--P:rRNA processing

KEGG

sce:YNL182C

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008357	Aspergillus clavatus	24.68	2.00e-17	82.00
IUUC-Afl-008564	Aspergillus flavus	25.35	6.00e-17	80.50
IUUC-Afu-009113	Aspergillus fumigatus	23.91	2.00e-17	81.60
IUUC-Ani-009132	Aspergillus nidulans	23.80	1.00e-16	79.30
IUUC-Ang-009586	Aspergillus niger	25.56	3.00e-20	90.90
IUUC-Aor-009882	Aspergillus oryzae	25.35	4.00e-17	80.90
IUUC-Ate-010249	Aspergillus terreus	24.38	2.00e-19	88.60
IUUC-Ame-010912	Astyanax mexicanus	25.69	4.00e-20	90.50
IUUC-Bta-013402	Bos taurus	25.64	7.00e-10	56.60
IUUC-Bci-013791	Botrytis cinerea	22.53	2.00e-09	55.10
IUUC-Cja-019758	Callithrix jacchus	22.16	4.00e-12	63.90
IUUC-Cfa-020495	Canis familiaris	23.83	2.00e-10	57.80
IUUC-Csa-023416	Chlorocebus sabaeus	24.20	9.00e-14	69.30
IUUC-Csv-025918	Ciona savignyi	23.31	7.00e-15	73.20
IUUC-Cgl-026618	Colletotrichum gloeosporioides	22.46	9.00e-10	55.80
IUUC-Cne-026843	Cryptococcus neoformans	24.37	7.00e-19	86.70
IUUC-Cme-027256	Cyanidioschyzon merolae	20.65	2.00e-03	35.40
IUUC-Dre-027560	Danio rerio	23.06	2.00e-18	85.10
IUUC-Dse-031492	Dothistroma septosporum	25.67	5.00e-15	73.60
IUUC-Dme-032059	Drosophila melanogaster	24.92	3.00e-15	74.30
IUUC-Fca-036068	Felis catus	23.26	3.00e-08	50.80
IUUC-Fox-037903	Fusarium oxysporum	22.71	1.00e-08	52.40
IUUC-Gmo-039323	Gadus morhua	24.94	6.00e-14	69.70
IUUC-Ggr-040050	Gaeumannomyces graminis	26.15	1.00e-09	55.50
IUUC-Gac-042641	Gasterosteus aculeatus	21.04	2.00e-14	71.60
IUUC-Ggo-045137	Gorilla gorilla	24.13	2.00e-10	58.50
IUUC-Hsa-046335	Homo sapiens	23.84	7.00e-10	56.60
IUUC-Itr-048032	Ictidomys tridecemlineatus	22.32	1.00e-13	68.90
IUUC-Kpa-049129	Komagataella pastoris	28.20	2.00e-44	171.00
IUUC-Lch-049532	Latimeria chalumnae	24.87	4.00e-21	94.00
IUUC-Loc-052471	Lepisosteus oculatus	22.30	5.00e-15	73.20
IUUC-Lma-053091	Leptosphaeria maculans	23.20	1.00e-16	79.30
IUUC-Laf-054331	Loxodonta africana	22.67	7.00e-12	63.20
IUUC-Mcc-055803	Macaca mulatta	24.20	9.00e-14	69.30
IUUC-Meu-056090	Macropus eugenii	22.16	6.00e-16	76.60
IUUC-Mor-057160	Magnaporthe oryzae	25.74	3.00e-09	54.30
IUUC-Mla-058943	Melampsora laricipopulina	30.18	6.00e-15	73.60
IUUC-Mga-059282	Meleagris gallopavo	22.09	5.00e-11	60.10
IUUC-Mvi-060315	Microbotryum violaceum	27.70	3.00e-17	81.30
IUUC-Nfi-068454	Neosartorya fischeri	23.65	7.00e-17	80.10
IUUC-Ncr-068914	Neurospora crassa	22.87	6.00e-14	69.70
IUUC-Nle-069518	Nomascus leucogenys	23.62	3.00e-13	67.80
IUUC-Ont-071435	Oreochromis niloticus	24.13	1.00e-19	89.00
IUUC-Ola-086571	Oryzias latipes	24.30	4.00e-18	83.60
IUUC-Oar-090131	Ovis aries	22.55	1.00e-10	58.50
IUUC-Pan-092810	Papio anubis	24.20	8.00e-14	69.30
IUUC-Pno-095047	Phaeosphaeria nodorum	24.11	2.00e-11	62.00
IUUC-Pfo-096996	Poecilia formosa	23.47	2.00e-14	72.00
IUUC-Pab-097747	Pongo abelii	23.91	3.00e-13	67.80
IUUC-Pca-100972	Procavia capensis	25.81	2.00e-10	57.80
IUUC-Pte-104120	Pyrenophora teres	23.14	4.00e-17	80.90
IUUC-Pyt-104558	Pyrenophora triticirepentis	22.80	2.00e-17	81.60
IUUC-Sja-107783	Schizosaccharomyces japonicus	25.07	9.00e-26	108.00
IUUC-Spo-108192	Schizosaccharomyces pombe	25.81	2.00e-22	97.80
IUUC-Ssl-108384	Sclerotinia sclerotiorum	24.20	8.00e-10	56.20
IUUC-Sre-115223	Sporisorium reilianum	23.89	9.00e-23	99.80
IUUC-Ssc-115627	Sus scrofa	25.64	2.00e-10	57.80
IUUC-Tru-117629	Takifugu rubripes	22.91	9.00e-16	75.90
IUUC-Tni-119839	Tetraodon nigroviridis	22.60	5.00e-13	66.60
IUUC-Tre-122047	Trichoderma reesei	22.52	1.00e-11	62.00
IUUC-Tvi-122668	Trichoderma virens	23.80	2.00e-12	64.70
IUUC-Tme-127070	Tuber melanosporum	23.23	3.00e-20	90.90
IUUC-Ttr-128735	Tursiops truncatus	26.28	6.00e-11	59.70
IUUC-Uma-129521	Ustilago maydis	23.59	2.00e-23	102.00
IUUC-Xtr-131838	Xenopus tropicalis	23.92	2.00e-14	71.20
IUUC-Xma-134106	Xiphophorus maculatus	25.41	2.00e-12	64.30

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence