iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	RAID2
Protein-protein Interaction
IID	iRefIndex
Post-translational Modifications (PTMs)
dbPAF	PHOSIDA
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.40e-30	103.5	464	495
UBD/Beta-Prp	1.80e-46	159.0	352	550

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf..sdtllvsGsdDgtikvWDl 30
           gHtd ++++a+  s+ +lvs+s D t+++W++
   Q: 464  GHTDAIWSVAYhsSNSRLVSASSDSTVRLWEP 495
           8***********65599*************96 PP

UBD/Beta-Prp

   S: 45   lrslsgheaevtavkfspdgkilvtgseDrtikvwdls............tgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdle..tgqclee 131
             +l +h + ++a++f+p +++l t+seD++ik+w+l+              ++v+t++gh+  vl+l +sp+gd+l +G+ d  i +++++  +g  + +
   Q: 352  KVTLRSHLDSIRAMQFHPVEPVLFTASEDGLIKLWNLDqkkdekhnsggtELEPVYTFRGHKGPVLCLVLSPTGDHLYTGGIDGNICCFNVPssNGDPFDS 452
           56899********************************************999************************************8875114555555 PP
   S: 132  ........tlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvysls...fdsngkelvsgsldgtvklwdlqtgecvrtl 218
                   tl+gh++++++v++h++++ lvs+s D+tvrlW   +g+ l +  g+ ++ +  +s   ++ +  +l+++ ++ + ++ d+ tg++v+ +
   Q: 453  ydprvlteTLTGHTDAIWSVAYHSSNSRLVSASSDSTVRLWEPGNGEPLIRTIGAPKSGILPTSvdfVSTETSHLLAAYTNCYAQIIDIDTGSTVMVF 550
           88888888***********************************888876666566888885444445555669******************9998765 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MEDASQLSNS QNDKAKDETT RPQYTMSGIL HFIQHEWTKN ELDRTRWEAE RAEMQARIAF 60
LQGERKGQEN LKQDLVRRIK MLEFCLKQER AKNYRLTHNG EEPPSLEESP NENSAPSENS 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AGCTTTTGCA CTTGCTTCAT TAACGTAAAT TACTCGAAAT AAGATCGGAT TCGAGTAGTT 60
TACAATGGAG GACGCCAGTC AATTGTCAAA CTCACAAAAT GACAAAGCAA AGGACGAAAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0175--Coiled coil
KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR013258--Striatin_N
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF08232--Striatin
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

KEGG

cel:CELE_K07C5.8

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-002046	Ailuropoda melanoleuca	49.54	7.00e-101	360.00
IUUC-Apl-003472	Anas platyrhynchos	50.46	7.00e-102	363.00
IUUC-Aca-005286	Anolis carolinensis	48.36	1.00e-99	356.00
IUUC-Acl-008170	Aspergillus clavatus	40.96	2.00e-16	80.10
IUUC-Afl-008585	Aspergillus flavus	41.67	8.00e-19	87.80
IUUC-Ani-009405	Aspergillus nidulans	27.03	5.00e-28	118.00
IUUC-Aor-009982	Aspergillus oryzae	41.67	9.00e-19	87.80
IUUC-Ame-010997	Astyanax mexicanus	49.55	2.00e-103	369.00
IUUC-Bgr-012143	Blumeria graminis	25.33	2.00e-31	129.00
IUUC-Bta-012797	Bos taurus	49.54	3.00e-100	358.00
IUUC-Bci-013742	Botrytis cinerea	24.83	2.00e-31	129.00
IUUC-Cja-018786	Callithrix jacchus	50.30	9.00e-102	363.00
IUUC-Cfa-021098	Canis familiaris	49.54	1.00e-100	359.00
IUUC-Cpo-022357	Cavia porcellus	50.46	2.00e-102	365.00
IUUC-Csa-023725	Chlorocebus sabaeus	49.85	2.00e-101	362.00
IUUC-Cho-024338	Choloepus hoffmanni	44.38	3.00e-84	305.00
IUUC-Cin-025167	Ciona intestinalis	37.98	2.00e-92	332.00
IUUC-Csv-026143	Ciona savignyi	46.36	9.00e-91	326.00
IUUC-Cne-026783	Cryptococcus neoformans	30.53	3.00e-51	195.00
IUUC-Dre-027566	Danio rerio	46.51	1.00e-105	375.00
IUUC-Dno-029926	Dasypus novemcinctus	49.54	2.00e-101	362.00
IUUC-Dor-030721	Dipodomys ordii	45.97	3.00e-92	331.00
IUUC-Dse-031486	Dothistroma septosporum	26.03	2.00e-32	132.00
IUUC-Dme-032158	Drosophila melanogaster	51.98	8.00e-104	370.00
IUUC-Ete-032770	Echinops telfairi	42.86	2.00e-80	291.00
IUUC-Eca-033309	Equus caballus	49.09	5.00e-100	357.00
IUUC-Eeu-034953	Erinaceus europaeus	48.36	4.00e-101	360.00
IUUC-Fca-036530	Felis catus	48.96	7.00e-103	367.00
IUUC-Fal-037408	Ficedula albicollis	50.46	3.00e-102	364.00
IUUC-Fox-037678	Fusarium oxysporum	38.83	1.00e-19	90.50
IUUC-Gmo-039653	Gadus morhua	37.52	9.00e-129	452.00
IUUC-Gga-041218	Gallus gallus	50.15	5.00e-102	363.00
IUUC-Gac-042142	Gasterosteus aculeatus	48.94	4.00e-101	360.00
IUUC-Ggo-045607	Gorilla gorilla	50.15	4.00e-102	364.00
IUUC-Hsa-045717	Homo sapiens	49.54	1.00e-100	359.00
IUUC-Itr-048177	Ictidomys tridecemlineatus	48.96	2.00e-99	355.00
IUUC-Lch-050441	Latimeria chalumnae	45.10	3.00e-103	368.00
IUUC-Loc-052193	Lepisosteus oculatus	45.36	4.00e-103	367.00
IUUC-Lma-053183	Leptosphaeria maculans	24.94	3.00e-32	133.00
IUUC-Laf-053964	Loxodonta africana	49.85	3.00e-98	351.00
IUUC-Mcc-055639	Macaca mulatta	49.85	1.00e-101	362.00
IUUC-Meu-056845	Macropus eugenii	43.67	2.00e-84	305.00
IUUC-Mpo-057337	Magnaporthe poae	25.86	2.00e-26	112.00
IUUC-Mla-058988	Melampsora laricipopulina	30.43	9.00e-49	187.00
IUUC-Mga-059885	Meleagris gallopavo	50.15	6.00e-101	359.00
IUUC-Mmr-061084	Microcebus murinus	49.85	3.00e-101	361.00
IUUC-Mdo-063016	Monodelphis domestica	49.54	9.00e-101	360.00
IUUC-Mmu-063914	Mus musculus	49.24	4.00e-100	357.00
IUUC-Mpu-065827	Mustela putorius furo	48.50	6.00e-102	363.00
IUUC-Mlu-067102	Myotis lucifugus	48.36	2.00e-100	359.00
IUUC-Nfi-068560	Neosartorya fischeri	40.96	2.00e-16	79.70
IUUC-Ncr-068831	Neurospora crassa	40.78	4.00e-19	89.00
IUUC-Nle-070032	Nomascus leucogenys	49.85	2.00e-101	362.00
IUUC-Opr-070496	Ochotona princeps	44.68	2.00e-87	315.00
IUUC-Ont-072025	Oreochromis niloticus	49.25	5.00e-104	370.00
IUUC-Oan-072822	Ornithorhynchus anatinus	48.96	4.00e-100	357.00
IUUC-Ocu-073876	Oryctolagus cuniculus	49.54	4.00e-101	361.00
IUUC-Ola-086321	Oryzias latipes	48.63	1.00e-99	356.00
IUUC-Oga-088045	Otolemur garnettii	50.15	2.00e-101	362.00
IUUC-Oar-090304	Ovis aries	48.36	3.00e-101	361.00
IUUC-Ptr-090871	Pan troglodytes	49.85	6.00e-102	363.00
IUUC-Pan-092139	Papio anubis	49.70	5.00e-100	357.00
IUUC-Psi-093424	Pelodiscus sinensis	50.15	4.00e-102	364.00
IUUC-Pma-094286	Petromyzon marinus	48.97	1.00e-94	338.00
IUUC-Pno-094905	Phaeosphaeria nodorum	27.01	3.00e-33	135.00
IUUC-Pfo-097042	Poecilia formosa	49.55	1.00e-103	369.00
IUUC-Pab-098626	Pongo abelii	45.64	4.00e-104	371.00
IUUC-Pca-100746	Procavia capensis	38.06	2.00e-66	245.00
IUUC-Pva-102824	Pteropus vampyrus	48.36	3.00e-101	361.00
IUUC-Pgr-103483	Puccinia graminis	31.79	1.00e-45	177.00
IUUC-Ptt-103828	Puccinia triticina	31.85	3.00e-39	156.00
IUUC-Pte-104374	Pyrenophora teres	25.12	4.00e-29	122.00
IUUC-Pyt-104568	Pyrenophora triticirepentis	25.58	3.00e-33	135.00
IUUC-Rno-105999	Rattus norvegicus	48.96	2.00e-100	358.00
IUUC-Sha-106786	Sarcophilus harrisii	49.54	8.00e-101	360.00
IUUC-Spo-108015	Schizosaccharomyces pombe	30.19	2.00e-21	96.30
IUUC-Ssl-108495	Sclerotinia sclerotiorum	24.60	4.00e-30	125.00
IUUC-Sar-113296	Sorex araneus	43.03	2.00e-57	215.00
IUUC-Sre-115115	Sporisorium reilianum	32.90	2.00e-54	206.00
IUUC-Ssc-115280	Sus scrofa	48.36	1.00e-101	362.00
IUUC-Tgu-116759	Taeniopygia guttata	47.16	4.00e-94	337.00
IUUC-Tru-117944	Takifugu rubripes	49.55	5.00e-103	367.00
IUUC-Tsy-119356	Tarsius syrichta	49.09	9.00e-50	190.00
IUUC-Tni-120571	Tetraodon nigroviridis	48.66	1.00e-101	362.00
IUUC-Tre-122113	Trichoderma reesei	27.94	1.00e-21	97.10
IUUC-Tme-126990	Tuber melanosporum	27.16	1.00e-31	130.00
IUUC-Tbe-128127	Tupaia belangeri	42.22	2.00e-83	302.00
IUUC-Ttr-128600	Tursiops truncatus	49.85	8.00e-101	360.00
IUUC-Uma-129659	Ustilago maydis	32.73	1.00e-55	210.00
IUUC-Vda-129673	Verticillium dahliae	40.96	4.00e-17	82.00
IUUC-Vpa-130294	Vicugna pacos	48.36	2.00e-101	361.00
IUUC-Xtr-132330	Xenopus tropicalis	45.88	4.00e-103	367.00
IUUC-Xma-133846	Xiphophorus maculatus	49.55	2.00e-102	365.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence