iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Details
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Basic Information

Integrated Annotations

Tag

Content

iUUCD ID

IUUC-Sce-106308

UUCD1 version

UUC-SaC-00230

Ensembl Protein ID

YDL064W

UniProt Accession

P50623; D6VRT3; UBC9_YEAST

Genbank Protein ID

CAA57888.1; CAA98629.1; DAA11793.1

Protein Name

SUMO-conjugating enzyme UBC9; RING-type E3 SUMO transferase UBC9; Ubiquitin carrier protein 9; Ubiquitin-conjugating enzyme E2-18 kDa; Ubiquitin-protein ligase

Genbank Nucleotide ID

X82538; Z74112; BK006938

Gene Name

UBC9; YDL064W

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
YDL064W	YDL064W	YDL064W

Annotation

mRNA Expression
GEO	FFGED
Protein-protein Interaction
IID	iRefIndex	HINT	Mentha
Protein 3D Structure
PDB	MMDB
Post-translational Modifications (PTMs)
CPLM	dbPAF	UniProt	BioGRID
Protein Expression/Proteomics
GPMDB

Status

Reviewed

Details

Family	Domain	References (PMIDs)
E2/UBC	E2_UBC	16782016

Classification

Family	E-value	Score	Start	End
E2/UBC	3.50e-46	154.9	8	148

Active Site

Position(s)	Description	Evidence
93	Glycyl thioester intermediate	{ECO:0000255\|PROSITE-ProRule:PRU00388, ECO:0000255\|PROSITE-ProRule:PRU10133}

Domain Profile

E2/UBC

   S: 1    Rlkkelkelekdppegisakpvdesd....ltewevlilGpedtpYeggvFkleiefpedYPfkPPkvkfltkifhPnvyenGkvClsilkeeekWspalsv 98
           Rl++e k+++kd+p g+ akpv+++d    l++we+ i G+e+t+++ggv+ +++e+p++YP+kPPkvkf   ++hPnvy++G++Clsil+e+++W+pa+++
   Q: 8    RLQEERKKWRKDHPFGFYAKPVKKADgsmdLQKWEAGIPGKEGTNWAGGVYPITVEYPNEYPSKPPKVKFPAGFYHPNVYPSGTICLSILNEDQDWRPAITL 109
           99*********************9988888************************************************************************ PP
   S: 99   esvllsiqsllaepnpesplneeaaellkknreeykkkv 137
           ++++l++q ll++pnp+sp++e a + +++n++ey+kkv
   Q: 110  KQIVLGVQDLLDSPNPNSPAQEPAWRSFSRNKAEYDKKV 148
           *************************************98 PP

Organism

Saccharomyces cerevisiae

Functional Description
(View)

E2 ubiquitin-like--protein ligase mediating SUMO/Smt3 attachment to septins and PCNA. Seems to be involved in degradation of S- (CLB5) and M-phase cyclins (CLB2).

Protein Sequence
(Fasta)

MSSLCLQRLQ EERKKWRKDH PFGFYAKPVK KADGSMDLQK WEAGIPGKEG TNWAGGVYPI 60
TVEYPNEYPS KPPKVKFPAG FYHPNVYPSG TICLSILNED QDWRPAITLK QIVLGVQDLL 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGAGTAGTT TGTGTCTACA GCGTCTTCAG GAAGAAAGGT AAGTAGTAGT TTTCCTCCTT 60
TTATGCTTAC ATTCTGTAGG CATACACAAT TTCATCCAGC GGTATACTAA CAAATCGATG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0067--ATP-binding
KW-0131--Cell cycle
KW-0132--Cell division
KW-0181--Complete proteome
KW-0498--Mitosis
KW-0547--Nucleotide-binding
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0808--Transferase
KW-0833--Ubl conjugation pathway

Interpro

IPR027230--Ubc9
IPR000608--UBQ-conjugat_E2
IPR023313--UBQ-conjugating_AS
IPR016135--UBQ-conjugating_enzyme/RWD

PROSITE

PS00183--UBIQUITIN_CONJUGAT_1
PS50127--UBIQUITIN_CONJUGAT_2

Pfam

PF00179--UQ_con

Gene Ontology

GO:0000794--C:condensed nuclear chromosome
GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0005524--F:ATP binding
GO:0019789--F:SUMO transferase activity
GO:0051301--P:cell division
GO:0000022--P:mitotic spindle elongation
GO:0016925--P:protein sumoylation
GO:0009737--P:response to abscisic acid

KEGG

sce:YDL064W

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000510	Aegilops tauschii	61.90	4.00e-38	148.00
IUUC-Aml-002383	Ailuropoda melanoleuca	56.41	1.00e-53	199.00
IUUC-Atr-002982	Amborella trichopoda	62.16	1.00e-43	166.00
IUUC-Apl-003840	Anas platyrhynchos	56.41	1.00e-53	199.00
IUUC-Aca-004772	Anolis carolinensis	56.41	1.00e-53	199.00
IUUC-Aly-005652	Arabidopsis lyrata	59.74	2.00e-55	205.00
IUUC-Ath-007084	Arabidopsis thaliana	59.74	2.00e-55	205.00
IUUC-Ago-007998	Ashbya gossypii	80.89	7.00e-78	280.00
IUUC-Acl-008040	Aspergillus clavatus	59.87	5.00e-48	181.00
IUUC-Afl-008563	Aspergillus flavus	58.55	3.00e-47	178.00
IUUC-Afu-008873	Aspergillus fumigatus	48.65	1.00e-42	163.00
IUUC-Ani-009222	Aspergillus nidulans	63.01	2.00e-50	189.00
IUUC-Ang-009740	Aspergillus niger	60.29	2.00e-43	166.00
IUUC-Aor-010170	Aspergillus oryzae	59.21	1.00e-47	179.00
IUUC-Ate-010410	Aspergillus terreus	61.64	2.00e-47	178.00
IUUC-Ame-011711	Astyanax mexicanus	55.77	5.00e-53	197.00
IUUC-Bgr-012012	Blumeria graminis	58.22	6.00e-50	187.00
IUUC-Bta-013269	Bos taurus	56.41	1.00e-53	199.00
IUUC-Bci-013748	Botrytis cinerea	57.82	2.00e-48	182.00
IUUC-Bdi-014883	Brachypodium distachyon	63.51	6.00e-56	207.00
IUUC-Bol-016125	Brassica oleracea	60.39	5.00e-45	171.00
IUUC-Bra-017235	Brassica rapa	60.39	5.00e-45	171.00
IUUC-Cel-018448	Caenorhabditis elegans	53.21	2.00e-51	192.00
IUUC-Cja-019349	Callithrix jacchus	56.41	1.00e-53	199.00
IUUC-Cfa-021008	Canis familiaris	60.71	6.00e-41	157.00
IUUC-Cpo-021324	Cavia porcellus	56.41	1.00e-53	199.00
IUUC-Cre-022836	Chlamydomonas reinhardtii	62.58	4.00e-59	218.00
IUUC-Csa-024207	Chlorocebus sabaeus	56.41	1.00e-53	199.00
IUUC-Cin-025734	Ciona intestinalis	60.26	9.00e-57	210.00
IUUC-Csv-026049	Ciona savignyi	58.97	6.00e-57	210.00
IUUC-Cgl-026699	Colletotrichum gloeosporioides	62.22	2.00e-52	195.00
IUUC-Cne-027034	Cryptococcus neoformans	57.89	6.00e-55	204.00
IUUC-Cme-027203	Cyanidioschyzon merolae	53.38	2.00e-41	159.00
IUUC-Dre-028839	Danio rerio	57.05	5.00e-54	201.00
IUUC-Dno-030037	Dasypus novemcinctus	56.41	1.00e-53	199.00
IUUC-Dor-030622	Dipodomys ordii	57.66	1.00e-46	176.00
IUUC-Dse-031366	Dothistroma septosporum	59.59	5.00e-54	201.00
IUUC-Dme-031818	Drosophila melanogaster	53.85	9.00e-52	193.00
IUUC-Ete-032517	Echinops telfairi	58.39	1.00e-47	179.00
IUUC-Eca-033789	Equus caballus	56.41	1.00e-53	199.00
IUUC-Fca-035851	Felis catus	56.41	1.00e-53	199.00
IUUC-Fal-037177	Ficedula albicollis	56.41	1.00e-53	199.00
IUUC-Fox-037789	Fusarium oxysporum	62.33	2.00e-57	212.00
IUUC-Fso-038166	Fusarium solani	61.64	1.00e-56	209.00
IUUC-Gmo-039482	Gadus morhua	57.05	7.00e-54	200.00
IUUC-Ggr-039892	Gaeumannomyces graminis	64.44	4.00e-53	199.00
IUUC-Gga-041199	Gallus gallus	56.41	1.00e-53	199.00
IUUC-Gac-042250	Gasterosteus aculeatus	57.05	7.00e-54	200.00
IUUC-Gma-043827	Glycine max	59.35	3.00e-55	204.00
IUUC-Ggo-045530	Gorilla gorilla	56.41	1.00e-53	199.00
IUUC-Hsa-046248	Homo sapiens	56.41	1.00e-53	199.00
IUUC-Hvu-047363	Hordeum vulgare	62.84	9.00e-56	206.00
IUUC-Itr-048429	Ictidomys tridecemlineatus	56.41	1.00e-53	199.00
IUUC-Kpa-049362	Komagataella pastoris	72.61	9.00e-69	249.00
IUUC-Lch-050644	Latimeria chalumnae	56.41	8.00e-54	200.00
IUUC-Lpe-051643	Leersia perrieri	61.49	5.00e-55	204.00
IUUC-Loc-052357	Lepisosteus oculatus	57.05	8.00e-54	200.00
IUUC-Lma-053142	Leptosphaeria maculans	58.90	1.00e-55	206.00
IUUC-Laf-053577	Loxodonta africana	56.41	1.00e-53	199.00
IUUC-Mcc-054925	Macaca mulatta	56.41	1.00e-53	199.00
IUUC-Meu-056094	Macropus eugenii	51.09	1.00e-37	146.00
IUUC-Mor-057141	Magnaporthe oryzae	61.64	2.00e-55	205.00
IUUC-Mpo-057613	Magnaporthe poae	64.44	4.00e-52	194.00
IUUC-Mtr-057933	Medicago truncatula	61.29	3.00e-57	211.00
IUUC-Mla-059115	Melampsora laricipopulina	59.48	4.00e-55	204.00
IUUC-Mga-059384	Meleagris gallopavo	56.41	1.00e-53	199.00
IUUC-Mvi-060328	Microbotryum violaceum	55.56	2.00e-43	166.00
IUUC-Mmr-061541	Microcebus murinus	56.41	1.00e-53	199.00
IUUC-Mdo-062540	Monodelphis domestica	56.41	1.00e-53	199.00
IUUC-Mmu-063818	Mus musculus	56.41	1.00e-53	199.00
IUUC-Mac-065429	Musa acuminata	62.16	1.00e-54	203.00
IUUC-Mpu-065734	Mustela putorius furo	56.41	1.00e-53	199.00
IUUC-Mlu-067619	Myotis lucifugus	56.41	1.00e-53	199.00
IUUC-Nfi-068567	Neosartorya fischeri	59.21	1.00e-47	180.00
IUUC-Ncr-068897	Neurospora crassa	61.64	4.00e-56	207.00
IUUC-Nle-069541	Nomascus leucogenys	56.13	7.00e-53	197.00
IUUC-Ont-071585	Oreochromis niloticus	57.05	7.00e-54	200.00
IUUC-Ocu-074588	Oryctolagus cuniculus	51.92	1.00e-46	176.00
IUUC-Oba-075803	Oryza barthii	63.51	4.00e-56	207.00
IUUC-Obr-076591	Oryza brachyantha	61.04	7.00e-57	210.00
IUUC-Ogl-077864	Oryza glaberrima	63.51	4.00e-56	207.00
IUUC-Ogu-077979	Oryza glumaepatula	62.59	3.00e-55	205.00
IUUC-Oin-080163	Oryza indica	63.51	4.00e-56	207.00
IUUC-Olo-080940	Oryza longistaminata	52.03	1.00e-45	172.00
IUUC-Ome-081909	Oryza meridionalis	62.59	3.00e-55	205.00
IUUC-Oni-082410	Oryza nivara	63.51	4.00e-56	207.00
IUUC-Opu-083206	Oryza punctata	62.84	5.00e-56	207.00
IUUC-Oru-084706	Oryza rufipogon	63.51	4.00e-56	207.00
IUUC-Osa-086079	Oryza sativa	63.51	4.00e-56	207.00
IUUC-Ola-086314	Oryzias latipes	56.41	2.00e-53	199.00
IUUC-Olu-087900	Ostreococcus lucimarinus	55.48	1.00e-54	202.00
IUUC-Oga-088729	Otolemur garnettii	58.39	8.00e-48	180.00
IUUC-Oar-090221	Ovis aries	56.41	2.00e-53	199.00
IUUC-Ptr-090528	Pan troglodytes	56.41	1.00e-53	199.00
IUUC-Pan-092834	Papio anubis	56.41	1.00e-53	199.00
IUUC-Psi-093001	Pelodiscus sinensis	56.41	2.00e-53	199.00
IUUC-Pma-094539	Petromyzon marinus	55.13	2.00e-52	196.00
IUUC-Pno-094954	Phaeosphaeria nodorum	59.86	1.00e-55	206.00
IUUC-Ppa-095778	Physcomitrella patens	60.14	2.00e-54	202.00
IUUC-Pfo-097457	Poecilia formosa	57.69	3.00e-54	201.00
IUUC-Pab-098205	Pongo abelii	56.41	1.00e-53	199.00
IUUC-Pop-099063	Populus trichocarpa	62.16	7.00e-55	203.00
IUUC-Pca-100603	Procavia capensis	58.39	3.00e-47	179.00
IUUC-Ppe-101501	Prunus persica	61.49	3.00e-44	168.00
IUUC-Pva-103251	Pteropus vampyrus	46.72	7.00e-33	130.00
IUUC-Pte-104067	Pyrenophora teres	59.59	4.00e-55	204.00
IUUC-Pyt-104436	Pyrenophora triticirepentis	59.59	4.00e-55	204.00
IUUC-Rno-105794	Rattus norvegicus	56.41	1.00e-53	199.00
IUUC-Sha-106997	Sarcophilus harrisii	49.37	1.00e-44	170.00
IUUC-Sja-108000	Schizosaccharomyces japonicus	61.04	1.00e-50	189.00
IUUC-Spo-108311	Schizosaccharomyces pombe	61.69	1.00e-51	192.00
IUUC-Smo-108685	Selaginella moellendorffii	57.43	4.00e-42	161.00
IUUC-Sit-110037	Setaria italica	63.51	6.00e-56	207.00
IUUC-Sly-110998	Solanum lycopersicum	62.84	6.00e-56	207.00
IUUC-Stu-111975	Solanum tuberosum	60.39	9.00e-48	180.00
IUUC-Sbi-114521	Sorghum bicolor	62.84	2.00e-55	205.00
IUUC-Sre-114957	Sporisorium reilianum	58.33	2.00e-56	209.00
IUUC-Ssc-116173	Sus scrofa	56.41	1.00e-53	199.00
IUUC-Tgu-116668	Taeniopygia guttata	56.41	2.00e-53	199.00
IUUC-Tru-118365	Takifugu rubripes	57.05	3.00e-54	201.00
IUUC-Tni-120455	Tetraodon nigroviridis	57.05	2.00e-54	202.00
IUUC-Tca-120956	Theobroma cacao	60.81	5.00e-54	201.00
IUUC-Tre-121927	Trichoderma reesei	60.27	2.00e-55	206.00
IUUC-Tvi-122363	Trichoderma virens	61.64	1.00e-56	209.00
IUUC-Tae-123228	Triticum aestivum	62.84	9.00e-56	208.00
IUUC-Tur-126625	Triticum urartu	60.81	1.00e-54	203.00
IUUC-Tme-126981	Tuber melanosporum	58.11	5.00e-40	154.00
IUUC-Uma-129582	Ustilago maydis	58.33	9.00e-57	210.00
IUUC-Vda-129845	Verticillium dahliae	59.59	1.00e-55	206.00
IUUC-Vpa-130242	Vicugna pacos	58.39	1.00e-47	179.00
IUUC-Vvi-130948	Vitis vinifera	59.09	4.00e-54	201.00
IUUC-Xtr-132540	Xenopus tropicalis	56.41	1.00e-53	199.00
IUUC-Xma-133010	Xiphophorus maculatus	57.69	3.00e-54	201.00
IUUC-Yli-134673	Yarrowia lipolytica	62.34	3.00e-61	225.00
IUUC-Zma-135004	Zea mays	63.51	2.00e-56	209.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence