iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSMMUG00000004660.3	ENSMMUT00000048273.2	ENSMMUP00000041308.2
ENSMMUG00000004660.3	ENSMMUT00000053512.1	ENSMMUP00000058228.1
ENSMMUG00000004660.3	ENSMMUT00000066966.1	ENSMMUP00000046977.1
ENSMMUG00000004660.3	ENSMMUT00000072149.1	ENSMMUP00000055313.1
ENSMMUG00000004660.3	ENSMMUT00000006589.3	ENSMMUP00000006198.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-65	223.1	105	480
ULD/UDP/UBQ/UBQ_Other	2.70e-09	37.9	5	74

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrelllekkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefs.... 85
           +Gl+NlgNtCYmN+++Qc+ ++pel+++l++ +  +l+++ +  + + ++ +l++lf ++ +++++++ p  ll+ l+++ ++f     
   Q: 105  CGLTNLGNTCYMNATVQCIRSVPELKDALKR-YAGALRASGEMASAQYITAALRDLFDSM-DKTSSSIPPIILLQFLHMAFPQFAekge 191
           7******************************.****************************.99999******************999*9 PP
   S: 86   ..gyeqqDaqEflaflldqleeelkkeknkpkeeeeeedkselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldl 172
             +y qqDa+E++ +++  l+++l+  ++ +++e+        s++a+  +++k+ksli++ F++++++++kc e +++ +++ + ++l
   Q: 192  qgQYLQQDANECWIQMMRVLQQKLEAIEDDSVKETD-------SSSASAATPSKKKSLIDQFFGVEFETTMKCTESEEEEVTKGKENQL 273
           999*********************664444444443.......33478899**************************999999888888 PP
   S: 173  slpvpgkeetkkeslqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksrekinkkvefpleLdl 261
           +l+   ++e   + l   L+   +ee  +     ++++ +++    k+ k+++lP +L++++ Rf ++e+++++ k+ k v+fpl+Ld+
   Q: 274  QLSCFINQEV--KYLFTGLKLRLQEEITK-----QSPTLQRNALYIKSSKISRLPAYLTIQMVRFFYKEKESVNAKVLKDVKFPLMLDM 355
           8888877754..58999999999999998.....58899999999******************************************** PP
   S: 262  spfcts........................peekqke...........................kkkYeLiavvvHsG.slssGHYvay 298
            + ct                         p     +                           +  Y+L av+ H+G s+ssGHYv++
   Q: 356  YELCTPelqekmvsfrskfkdledkkvnqqP-----NtsdkksspqkevkyepfsfaddigsnnCGYYDLQAVLTHQGrSSSSGHYVSW 439
           ******6666666666666666665555551.....0555556666677777777777777777************************* PP
   S: 299  vknekgkWllfdDskVtevkeeevleetg....staYvlfY 335
           vk ++++W++fdD+kV+ v+ e++l+ +g    + aYvl+Y
   Q: 440  VKRKQDEWIKFDDDKVSIVTPEDILRLSGggdwHIAYVLLY 480
           **************************988************ PP

ULD/UDP/UBQ/UBQ_Other

   S: 2    qvtvksldgseltlkvnpsdtVaeLKekiekklgippeqqrLiykGkiLeddktLadyglkdgstihllek 72
           +vtvk+ + +  ++++n +++  ++K +++ ++g++p++q+ ++kG  L+dd ++++ ++k+g+t++++ +
   Q: 5    SVTVKWGKEKFEGVELNTDEPPMVFKAQLFALTGVQPARQKVMVKGGTLKDD-DWGNIKIKNGMTLLMMGS 74
           69********99*************************************999.9**************965 PP

Organism

Macaca mulatta

Protein Sequence
(Fasta)

MPLYSVTVKW GKEKFEGVEL NTDEPPMVFK AQLFALTGVQ PARQKVMVKG GTLKDDDWGN 60
IKIKNGMTLL MMGSADALPE EPSAKTVFVE DMTEEQLASA MELPCGLTNL GNTCYMNATV 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCTTGTCAGG CCCAGCCCTC CTGCGCCGCC GCCTCCCGCC GCGCCCCGCC ATGCCGCTCT 60
ACTCCGGTGA GCCCCGTCCT GGCCTCGCGC GCAGTACACG GGGCCGGCGC TAGGCCTCCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0378--Hydrolase
KW-1185--Reference proteome

Interpro

IPR001394--Peptidase_C19_UCH
IPR029071--Ubiquitin-rel_dom
IPR019954--Ubiquitin_CS
IPR000626--Ubiquitin_dom
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS00299--UBIQUITIN_1
PS50053--UBIQUITIN_2
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF00443--UCH

SMART

SM00213--UBQ

Gene Ontology

GO:0036459--F:thiol-dependent ubiquitinyl hydrolase activity
GO:0016579--P:protein deubiquitination
GO:0006511--P:ubiquitin-dependent protein catabolic process

KEGG

mcc:698087

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000893	Aegilops tauschii	43.96	2.00e-38	154.00
IUUC-Aml-002053	Ailuropoda melanoleuca	98.98	0.00e+00	933.00
IUUC-Atr-002725	Amborella trichopoda	42.03	1.00e-102	367.00
IUUC-Apl-004031	Anas platyrhynchos	91.24	0.00e+00	891.00
IUUC-Aca-004361	Anolis carolinensis	89.27	0.00e+00	910.00
IUUC-Aly-006078	Arabidopsis lyrata	42.20	3.00e-112	398.00
IUUC-Ath-007623	Arabidopsis thaliana	42.18	1.00e-112	400.00
IUUC-Ago-007796	Ashbya gossypii	32.22	2.00e-58	220.00
IUUC-Acl-008258	Aspergillus clavatus	36.52	8.00e-65	241.00
IUUC-Afl-008732	Aspergillus flavus	33.33	4.00e-72	265.00
IUUC-Afu-008755	Aspergillus fumigatus	34.83	1.00e-79	290.00
IUUC-Ani-009148	Aspergillus nidulans	37.90	4.00e-70	259.00
IUUC-Ang-009878	Aspergillus niger	37.32	3.00e-65	243.00
IUUC-Aor-010239	Aspergillus oryzae	33.33	5.00e-72	265.00
IUUC-Ate-010243	Aspergillus terreus	33.74	1.00e-70	261.00
IUUC-Ame-011327	Astyanax mexicanus	50.91	8.00e-127	447.00
IUUC-Bgr-012231	Blumeria graminis	34.15	3.00e-79	289.00
IUUC-Bta-012553	Bos taurus	97.57	0.00e+00	947.00
IUUC-Bci-013606	Botrytis cinerea	39.95	7.00e-70	258.00
IUUC-Bdi-014567	Brachypodium distachyon	42.91	4.00e-112	398.00
IUUC-Bol-016127	Brassica oleracea	42.60	3.00e-114	405.00
IUUC-Bra-017501	Brassica rapa	42.40	2.00e-113	402.00
IUUC-Cel-018140	Caenorhabditis elegans	41.55	2.00e-100	359.00
IUUC-Cja-019516	Callithrix jacchus	98.99	0.00e+00	965.00
IUUC-Cfa-020808	Canis familiaris	99.19	0.00e+00	959.00
IUUC-Cpo-021688	Cavia porcellus	96.96	0.00e+00	939.00
IUUC-Cre-022663	Chlamydomonas reinhardtii	37.78	7.00e-83	301.00
IUUC-Csa-023429	Chlorocebus sabaeus	99.80	0.00e+00	946.00
IUUC-Cho-024347	Choloepus hoffmanni	97.77	0.00e+00	954.00
IUUC-Cin-025198	Ciona intestinalis	54.38	6.00e-151	527.00
IUUC-Csv-026007	Ciona savignyi	53.01	4.00e-153	534.00
IUUC-Cgl-026757	Colletotrichum gloeosporioides	38.44	1.00e-63	237.00
IUUC-Cne-026963	Cryptococcus neoformans	34.68	2.00e-76	279.00
IUUC-Cme-027240	Cyanidioschyzon merolae	30.62	7.00e-60	224.00
IUUC-Dre-027647	Danio rerio	82.45	0.00e+00	831.00
IUUC-Dno-029967	Dasypus novemcinctus	97.97	0.00e+00	935.00
IUUC-Dor-030886	Dipodomys ordii	92.26	0.00e+00	762.00
IUUC-Dse-031466	Dothistroma septosporum	35.03	7.00e-57	215.00
IUUC-Dme-032079	Drosophila melanogaster	55.35	5.00e-159	554.00
IUUC-Ete-032351	Echinops telfairi	86.21	0.00e+00	858.00
IUUC-Eca-033461	Equus caballus	97.97	0.00e+00	992.00
IUUC-Eeu-035220	Erinaceus europaeus	74.13	0.00e+00	687.00
IUUC-Fca-036210	Felis catus	99.39	0.00e+00	961.00
IUUC-Fal-037528	Ficedula albicollis	90.65	0.00e+00	874.00
IUUC-Fox-037805	Fusarium oxysporum	39.90	1.00e-70	260.00
IUUC-Fso-038177	Fusarium solani	37.82	1.00e-67	250.00
IUUC-Gmo-038953	Gadus morhua	78.21	0.00e+00	767.00
IUUC-Ggr-039972	Gaeumannomyces graminis	34.12	7.00e-74	271.00
IUUC-Gga-040462	Gallus gallus	90.26	0.00e+00	884.00
IUUC-Gac-041312	Gasterosteus aculeatus	81.72	0.00e+00	802.00
IUUC-Gma-043255	Glycine max	42.43	5.00e-109	388.00
IUUC-Ggo-045458	Gorilla gorilla	82.63	0.00e+00	788.00
IUUC-Hsa-045706	Homo sapiens	100.00	0.00e+00	947.00
IUUC-Hvu-047821	Hordeum vulgare	46.76	1.00e-57	216.00
IUUC-Itr-048654	Ictidomys tridecemlineatus	97.97	0.00e+00	960.00
IUUC-Lch-050464	Latimeria chalumnae	82.45	0.00e+00	822.00
IUUC-Lpe-051419	Leersia perrieri	42.71	3.00e-108	385.00
IUUC-Loc-052732	Lepisosteus oculatus	80.85	0.00e+00	841.00
IUUC-Lma-053177	Leptosphaeria maculans	40.51	1.00e-70	260.00
IUUC-Laf-053822	Loxodonta africana	97.97	0.00e+00	950.00
IUUC-Meu-056307	Macropus eugenii	82.58	0.00e+00	793.00
IUUC-Mor-057171	Magnaporthe oryzae	38.42	8.00e-68	251.00
IUUC-Mpo-057415	Magnaporthe poae	38.83	1.00e-69	257.00
IUUC-Mtr-057901	Medicago truncatula	43.00	1.00e-111	397.00
IUUC-Mla-058897	Melampsora laricipopulina	39.63	1.00e-75	277.00
IUUC-Mga-060016	Meleagris gallopavo	90.84	0.00e+00	888.00
IUUC-Mvi-060562	Microbotryum violaceum	38.77	3.00e-67	249.00
IUUC-Mmr-060624	Microcebus murinus	97.97	0.00e+00	997.00
IUUC-Mdo-061809	Monodelphis domestica	93.32	0.00e+00	900.00
IUUC-Mmu-063869	Mus musculus	96.75	0.00e+00	939.00
IUUC-Mac-064876	Musa acuminata	39.68	1.00e-96	347.00
IUUC-Mpu-066480	Mustela putorius furo	98.78	0.00e+00	956.00
IUUC-Mlu-067866	Myotis lucifugus	97.36	0.00e+00	955.00
IUUC-Nfi-068393	Neosartorya fischeri	36.38	4.00e-65	242.00
IUUC-Ncr-068815	Neurospora crassa	35.66	9.00e-82	297.00
IUUC-Nle-070121	Nomascus leucogenys	100.00	5.00e-141	493.00
IUUC-Opr-070712	Ochotona princeps	77.34	3.00e-173	601.00
IUUC-Ont-071544	Oreochromis niloticus	81.87	0.00e+00	769.00
IUUC-Oan-073635	Ornithorhynchus anatinus	91.57	0.00e+00	744.00
IUUC-Ocu-074926	Oryctolagus cuniculus	97.16	0.00e+00	931.00
IUUC-Oba-075633	Oryza barthii	42.18	3.00e-108	385.00
IUUC-Obr-076423	Oryza brachyantha	42.86	2.00e-110	392.00
IUUC-Ogl-077913	Oryza glaberrima	42.02	4.00e-111	394.00
IUUC-Ogu-078435	Oryza glumaepatula	42.18	3.00e-108	385.00
IUUC-Oin-080072	Oryza indica	42.15	2.00e-108	386.00
IUUC-Olo-080535	Oryza longistaminata	39.00	6.00e-93	334.00
IUUC-Ome-081309	Oryza meridionalis	42.18	3.00e-108	385.00
IUUC-Oni-083113	Oryza nivara	42.18	3.00e-108	385.00
IUUC-Opu-083168	Oryza punctata	41.24	1.00e-102	366.00
IUUC-Oru-084253	Oryza rufipogon	42.18	3.00e-108	385.00
IUUC-Osa-085554	Oryza sativa	42.02	5.00e-111	394.00
IUUC-Ola-086998	Oryzias latipes	81.14	0.00e+00	794.00
IUUC-Olu-087818	Ostreococcus lucimarinus	36.09	5.00e-71	261.00
IUUC-Oga-088571	Otolemur garnettii	97.97	0.00e+00	948.00
IUUC-Oar-089526	Ovis aries	97.35	0.00e+00	940.00
IUUC-Ptr-091433	Pan troglodytes	100.00	0.00e+00	947.00
IUUC-Pan-091966	Papio anubis	99.80	0.00e+00	946.00
IUUC-Psi-093458	Pelodiscus sinensis	89.22	0.00e+00	851.00
IUUC-Pma-094343	Petromyzon marinus	68.86	4.00e-121	427.00
IUUC-Pno-095109	Phaeosphaeria nodorum	39.65	1.00e-65	244.00
IUUC-Ppa-095756	Physcomitrella patens	43.90	2.00e-111	395.00
IUUC-Pfo-096514	Poecilia formosa	82.28	0.00e+00	785.00
IUUC-Pab-098477	Pongo abelii	87.45	0.00e+00	749.00
IUUC-Pop-099221	Populus trichocarpa	41.16	3.00e-103	368.00
IUUC-Pca-100791	Procavia capensis	81.54	3.00e-179	621.00
IUUC-Ppe-101812	Prunus persica	41.77	1.00e-107	383.00
IUUC-Pva-102462	Pteropus vampyrus	93.22	0.00e+00	766.00
IUUC-Pgr-103623	Puccinia graminis	40.69	6.00e-75	275.00
IUUC-Ptt-103767	Puccinia triticina	39.40	4.00e-68	252.00
IUUC-Pte-104109	Pyrenophora teres	38.94	1.00e-69	257.00
IUUC-Pyt-104766	Pyrenophora triticirepentis	40.56	5.00e-70	258.00
IUUC-Rno-105351	Rattus norvegicus	96.55	0.00e+00	903.00
IUUC-Sce-106168	Saccharomyces cerevisiae	32.41	1.00e-62	234.00
IUUC-Sha-107491	Sarcophilus harrisii	93.10	0.00e+00	912.00
IUUC-Sja-107769	Schizosaccharomyces japonicus	33.92	3.00e-78	285.00
IUUC-Spo-108174	Schizosaccharomyces pombe	37.63	7.00e-81	294.00
IUUC-Ssl-108659	Sclerotinia sclerotiorum	34.74	3.00e-84	305.00
IUUC-Smo-108805	Selaginella moellendorffii	43.27	7.00e-110	390.00
IUUC-Sit-110361	Setaria italica	42.34	4.00e-113	401.00
IUUC-Sly-110965	Solanum lycopersicum	40.35	2.00e-108	386.00
IUUC-Sar-113355	Sorex araneus	84.58	0.00e+00	661.00
IUUC-Sbi-114778	Sorghum bicolor	43.03	3.00e-112	399.00
IUUC-Sre-115011	Sporisorium reilianum	36.06	1.00e-61	231.00
IUUC-Ssc-116273	Sus scrofa	97.56	0.00e+00	934.00
IUUC-Tgu-117063	Taeniopygia guttata	90.02	0.00e+00	871.00
IUUC-Tru-118381	Takifugu rubripes	78.86	0.00e+00	790.00
IUUC-Tsy-119076	Tarsius syrichta	82.54	2.00e-119	422.00
IUUC-Tni-119941	Tetraodon nigroviridis	81.02	0.00e+00	781.00
IUUC-Tca-121246	Theobroma cacao	41.49	2.00e-109	389.00
IUUC-Tre-121969	Trichoderma reesei	34.49	2.00e-75	276.00
IUUC-Tvi-122543	Trichoderma virens	34.87	2.00e-77	283.00
IUUC-Tae-125484	Triticum aestivum	41.88	6.00e-109	387.00
IUUC-Tur-126128	Triticum urartu	41.87	2.00e-39	156.00
IUUC-Tbe-128030	Tupaia belangeri	91.17	0.00e+00	852.00
IUUC-Ttr-128701	Tursiops truncatus	96.69	0.00e+00	768.00
IUUC-Uma-129657	Ustilago maydis	36.80	9.00e-65	241.00
IUUC-Vda-129723	Verticillium dahliae	32.31	3.00e-71	263.00
IUUC-Vpa-130284	Vicugna pacos	70.64	0.00e+00	632.00
IUUC-Vvi-131037	Vitis vinifera	42.55	2.00e-108	385.00
IUUC-Xtr-132235	Xenopus tropicalis	86.06	0.00e+00	876.00
IUUC-Xma-133840	Xiphophorus maculatus	82.28	0.00e+00	810.00
IUUC-Yli-134453	Yarrowia lipolytica	36.78	3.00e-82	299.00
IUUC-Zma-135669	Zea mays	36.27	7.00e-94	337.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence