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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Mmu-063321
Ensembl Protein ID ENSMUSP00000006254.5
UniProt Accession Q9D1E6; Q9CWR6; Q9DCZ6; TBCB_MOUSE
Genbank Protein ID BAB22009.1; BAB22918.2; BAB26939.1; AAH10684.1
Protein Name Tubulin-folding cofactor B; Cytoskeleton-associated protein 1; Cytoskeleton-associated protein CKAPI; Tubulin-specific chaperone B
Genbank Nucleotide ID AK002316; AK003655; AK010438; BC010684
Gene Name Tbcb; Ckap1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMUSG00000006095.12 ENSMUST00000006254.5 ENSMUSP00000006254.5
Annotation
Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEOArrayExpressGXD
DNA & RNA Element
microRNATRANSFACRepTarmiRNAMap
RAID2
Protein-protein Interaction
IIDMentha
Protein 3D Structure
PDBMMDB
Post-translational Modifications (PTMs)
CPLMdbPAFPhosphositePlusdbPTM
UniProtPHOSIDAmUbiSiDa
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family Identity E-Value Score Source Orthology
ULD/UDP/UBQ/UBQ_Other 41.89 3.00e-43 171.00 IUUC-Cel-018176
ULD/UDP/UBQ/UBQ_Other 32.48 1.00e-26 114.00 IUUC-Spo-108310
Active Site
Position(s) Description Evidence
N/A N/A N/A
Organism Mus musculus
Functional Description
(View)

Functional Description


     Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation (PubMed:17184771). May function as a negative regulator of axonal growth (PubMed:17217416).
 Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer (By similarity). Involved in regulation of tubulin heterodimer dissociation (PubMed:17184771). May function as a negative regulator of axonal growth (PubMed:17217416).
Protein Sequence
(Fasta)
MEVTGISAPT VMVFISSSLN SFRSEKRYSR SLTIAEFKCK LELVVGSPAS CMELELYGAD 60
DKFYSKLDQE DALLGSYPVD DGCRIHVIDH SGVRLGEYED VSKVEKYEIS PEAYERRQNT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mmu-063321|ULD,UBQ_Other|Mus musculus
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Nucleotide Sequence
(Fasta)
CTGCACCAAA CTAGGGCGAT GCTGCGCGCA TGCGCGGGTT CCTTATTTTT TTATTTTTTT 60
TATTTTTTTT TTTATGGATG TCTGGCTGAC GGCTTGCGTC GATCCTTTGA TACCCTCTGC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mmu-063321|ULD,UBQ_Other|Mus musculus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0007--Acetylation
KW-0143--Chaperone
KW-0181--Complete proteome
KW-0963--Cytoplasm
KW-0206--Cytoskeleton
KW-0217--Developmental protein
KW-0221--Differentiation
KW-0493--Microtubule
KW-0524--Neurogenesis
KW-0597--Phosphoprotein
KW-1185--Reference proteome
KW-0832--Ubl conjugation
Interpro

IPR000938--CAP-Gly_domain
IPR029071--Ubiquitin-rel_dom
IPR000626--Ubiquitin_dom
PROSITE

PS00845--CAP_GLY_1
PS50245--CAP_GLY_2
Pfam

PF01302--CAP_GLY
PF14560--Ubiquitin_2
SMART

SM01052--CAP_GLY
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005829--C:cytosol
GO:0005874--C:microtubule
GO:0030154--P:cell differentiation
GO:0007399--P:nervous system development
KEGG mmu:66411
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000863 Aegilops tauschii 39.02 2.00e-25 109.00
IUUC-Aml-002358 Ailuropoda melanoleuca 87.15 3.00e-118 417.00
IUUC-Atr-003043 Amborella trichopoda 38.46 6.00e-35 140.00
IUUC-Aca-004737 Anolis carolinensis 71.84 3.00e-81 294.00
IUUC-Aly-005916 Arabidopsis lyrata 38.86 8.00e-35 140.00
IUUC-Ath-007038 Arabidopsis thaliana 38.86 4.00e-35 141.00
IUUC-Ago-007723 Ashbya gossypii 35.66 2.00e-14 72.80
IUUC-Acl-008216 Aspergillus clavatus 34.60 4.00e-33 134.00
IUUC-Afl-008534 Aspergillus flavus 34.13 4.00e-31 128.00
IUUC-Afu-008927 Aspergillus fumigatus 35.04 2.00e-31 129.00
IUUC-Ani-009283 Aspergillus nidulans 37.15 2.00e-32 132.00
IUUC-Ang-009564 Aspergillus niger 35.44 3.00e-32 132.00
IUUC-Aor-010034 Aspergillus oryzae 34.13 4.00e-31 128.00
IUUC-Ate-010424 Aspergillus terreus 35.74 2.00e-31 129.00
IUUC-Ame-011741 Astyanax mexicanus 61.89 4.00e-79 287.00
IUUC-Bgr-011988 Blumeria graminis 34.96 5.00e-30 124.00
IUUC-Bta-013304 Bos taurus 85.66 8.00e-118 416.00
IUUC-Bci-013694 Botrytis cinerea 40.98 8.00e-39 153.00
IUUC-Bdi-014585 Brachypodium distachyon 37.17 3.00e-32 132.00
IUUC-Bol-015891 Brassica oleracea 38.14 2.00e-35 142.00
IUUC-Bra-017389 Brassica rapa 38.72 2.00e-35 142.00
IUUC-Cel-018176 Caenorhabditis elegans 43.69 5.00e-47 181.00
IUUC-Cja-019754 Callithrix jacchus 89.34 3.00e-116 410.00
IUUC-Cfa-020813 Canis familiaris 90.98 3.00e-122 431.00
IUUC-Cpo-021932 Cavia porcellus 90.16 3.00e-120 424.00
IUUC-Cre-022753 Chlamydomonas reinhardtii 38.10 1.00e-32 132.00
IUUC-Csa-023261 Chlorocebus sabaeus 89.75 8.00e-117 412.00
IUUC-Cin-025428 Ciona intestinalis 48.18 1.00e-59 222.00
IUUC-Csv-025811 Ciona savignyi 49.07 4.00e-56 211.00
IUUC-Cgl-026504 Colletotrichum gloeosporioides 35.91 7.00e-31 127.00
IUUC-Cne-026867 Cryptococcus neoformans 35.80 6.00e-31 127.00
IUUC-Cme-027227 Cyanidioschyzon merolae 37.69 2.00e-13 69.30
IUUC-Dre-028683 Danio rerio 64.46 5.00e-80 290.00
IUUC-Dno-029817 Dasypus novemcinctus 89.34 1.00e-117 415.00
IUUC-Dor-030906 Dipodomys ordii 88.11 5.00e-112 396.00
IUUC-Dse-031240 Dothistroma septosporum 39.73 1.00e-33 136.00
IUUC-Dme-031894 Drosophila melanogaster 41.77 8.00e-49 186.00
IUUC-Eca-034216 Equus caballus 87.70 1.00e-126 444.00
IUUC-Eeu-035155 Erinaceus europaeus 83.01 3.00e-92 330.00
IUUC-Fca-035461 Felis catus 90.57 3.00e-122 430.00
IUUC-Fal-037458 Ficedula albicollis 49.30 5.00e-14 73.20
IUUC-Fox-037822 Fusarium oxysporum 38.50 2.00e-33 135.00
IUUC-Fso-038149 Fusarium solani 37.17 9.00e-33 133.00
IUUC-Gmo-038810 Gadus morhua 54.96 2.00e-70 258.00
IUUC-Ggr-039751 Gaeumannomyces graminis 30.00 2.00e-19 89.40
IUUC-Gga-040168 Gallus gallus 41.05 1.00e-14 73.90
IUUC-Gac-041700 Gasterosteus aculeatus 60.91 8.00e-79 286.00
IUUC-Gma-044336 Glycine max 39.57 6.00e-38 150.00
IUUC-Ggo-044442 Gorilla gorilla 88.41 9.00e-95 338.00
IUUC-Hsa-046441 Homo sapiens 89.34 7.00e-116 409.00
IUUC-Hvu-047163 Hordeum vulgare 38.01 7.00e-28 117.00
IUUC-Itr-048652 Ictidomys tridecemlineatus 88.93 2.00e-128 451.00
IUUC-Kpa-049126 Komagataella pastoris 32.80 2.00e-31 129.00
IUUC-Lch-050256 Latimeria chalumnae 65.56 5.00e-92 330.00
IUUC-Lpe-051676 Leersia perrieri 37.45 2.00e-31 129.00
IUUC-Loc-051891 Lepisosteus oculatus 66.67 5.00e-84 303.00
IUUC-Lma-052977 Leptosphaeria maculans 39.84 2.00e-34 139.00
IUUC-Laf-053381 Loxodonta africana 87.30 9.00e-117 412.00
IUUC-Mcc-055434 Macaca mulatta 89.75 8.00e-117 412.00
IUUC-Meu-056675 Macropus eugenii 67.08 1.00e-82 298.00
IUUC-Mor-056937 Magnaporthe oryzae 40.00 4.00e-30 124.00
IUUC-Mpo-057404 Magnaporthe poae 38.05 7.00e-30 124.00
IUUC-Mtr-058357 Medicago truncatula 40.54 1.00e-35 143.00
IUUC-Mla-059125 Melampsora laricipopulina 41.13 6.00e-42 164.00
IUUC-Mga-059996 Meleagris gallopavo 48.61 4.00e-14 72.40
IUUC-Mvi-060558 Microbotryum violaceum 34.38 9.00e-35 140.00
IUUC-Mmr-061473 Microcebus murinus 91.39 8.00e-122 429.00
IUUC-Mdo-061846 Monodelphis domestica 78.60 2.00e-103 368.00
IUUC-Mac-065590 Musa acuminata 38.40 1.00e-36 146.00
IUUC-Mpu-066149 Mustela putorius furo 90.16 2.00e-121 427.00
IUUC-Mlu-067002 Myotis lucifugus 88.93 1.00e-119 422.00
IUUC-Nfi-068351 Neosartorya fischeri 34.47 1.00e-29 123.00
IUUC-Ncr-068854 Neurospora crassa 34.91 9.00e-31 126.00
IUUC-Nle-069008 Nomascus leucogenys 83.61 1.00e-106 378.00
IUUC-Opr-070608 Ochotona princeps 83.20 2.00e-110 391.00
IUUC-Ont-071543 Oreochromis niloticus 61.57 1.00e-83 302.00
IUUC-Oan-073488 Ornithorhynchus anatinus 72.97 4.00e-68 250.00
IUUC-Ocu-073951 Oryctolagus cuniculus 90.16 2.00e-120 425.00
IUUC-Oba-075033 Oryza barthii 38.79 2.00e-35 142.00
IUUC-Obr-076908 Oryza brachyantha 38.63 3.00e-37 148.00
IUUC-Ogl-077907 Oryza glaberrima 38.36 8.00e-38 150.00
IUUC-Ogu-078871 Oryza glumaepatula 38.79 2.00e-35 142.00
IUUC-Oin-080206 Oryza indica 38.36 7.00e-38 150.00
IUUC-Olo-080756 Oryza longistaminata 52.38 2.00e-20 90.10
IUUC-Ome-081319 Oryza meridionalis 52.38 2.00e-20 90.10
IUUC-Oni-082550 Oryza nivara 38.63 9.00e-35 140.00
IUUC-Opu-083656 Oryza punctata 34.78 1.00e-32 133.00
IUUC-Oru-084482 Oryza rufipogon 38.79 2.00e-35 142.00
IUUC-Osa-085952 Oryza sativa 38.36 8.00e-38 150.00
IUUC-Ola-087407 Oryzias latipes 56.50 7.00e-79 286.00
IUUC-Olu-087778 Ostreococcus lucimarinus 36.99 2.00e-35 142.00
IUUC-Oga-088233 Otolemur garnettii 89.34 1.00e-116 412.00
IUUC-Oar-089581 Ovis aries 85.66 1.00e-124 438.00
IUUC-Ptr-091547 Pan troglodytes 89.34 7.00e-116 409.00
IUUC-Pan-092061 Papio anubis 89.75 8.00e-117 412.00
IUUC-Psi-093234 Pelodiscus sinensis 70.31 8.00e-73 266.00
IUUC-Pma-094359 Petromyzon marinus 57.53 1.00e-72 265.00
IUUC-Pno-094999 Phaeosphaeria nodorum 39.02 7.00e-37 147.00
IUUC-Ppa-095653 Physcomitrella patens 36.02 2.00e-29 122.00
IUUC-Pfo-096130 Poecilia formosa 58.85 3.00e-80 291.00
IUUC-Pop-099133 Populus trichocarpa 39.47 9.00e-38 150.00
IUUC-Pca-100784 Procavia capensis 77.05 1.00e-94 339.00
IUUC-Ppe-101764 Prunus persica 39.15 1.00e-37 149.00
IUUC-Pva-102882 Pteropus vampyrus 90.57 2.00e-123 434.00
IUUC-Pgr-103337 Puccinia graminis 38.66 1.00e-39 156.00
IUUC-Ptt-103764 Puccinia triticina 34.80 3.00e-29 122.00
IUUC-Pte-104265 Pyrenophora teres 37.61 5.00e-31 127.00
IUUC-Pyt-104528 Pyrenophora triticirepentis 28.47 7.00e-24 104.00
IUUC-Rno-104851 Rattus norvegicus 96.72 4.00e-124 436.00
IUUC-Sce-106183 Saccharomyces cerevisiae 28.99 2.00e-12 66.20
IUUC-Sha-106933 Sarcophilus harrisii 36.36 1.00e-06 48.50
IUUC-Sja-107978 Schizosaccharomyces japonicus 37.78 3.00e-32 131.00
IUUC-Spo-108310 Schizosaccharomyces pombe 34.19 8.00e-30 123.00
IUUC-Ssl-108484 Sclerotinia sclerotiorum 34.08 1.00e-25 109.00
IUUC-Sit-110751 Setaria italica 38.36 1.00e-32 133.00
IUUC-Sly-111811 Solanum lycopersicum 39.32 8.00e-37 146.00
IUUC-Stu-111984 Solanum tuberosum 39.74 2.00e-37 148.00
IUUC-Sar-113382 Sorex araneus 81.87 4.00e-78 283.00
IUUC-Sbi-113807 Sorghum bicolor 37.44 3.00e-29 121.00
IUUC-Sre-115083 Sporisorium reilianum 34.54 1.00e-31 129.00
IUUC-Ssc-116306 Sus scrofa 87.30 1.00e-118 418.00
IUUC-Tru-117880 Takifugu rubripes 63.22 7.00e-90 323.00
IUUC-Tni-119713 Tetraodon nigroviridis 63.91 6.00e-81 293.00
IUUC-Tca-121819 Theobroma cacao 39.91 3.00e-37 148.00
IUUC-Tre-122044 Trichoderma reesei 40.62 1.00e-34 139.00
IUUC-Tvi-122273 Trichoderma virens 40.18 2.00e-34 139.00
IUUC-Tae-123023 Triticum aestivum 38.46 1.00e-28 119.00
IUUC-Tur-126446 Triticum urartu 40.76 2.00e-23 101.00
IUUC-Tme-127153 Tuber melanosporum 37.04 1.00e-36 146.00
IUUC-Tbe-127834 Tupaia belangeri 88.19 4.00e-58 216.00
IUUC-Ttr-128351 Tursiops truncatus 71.31 6.00e-96 343.00
IUUC-Uma-129608 Ustilago maydis 32.14 1.00e-27 116.00
IUUC-Vda-129806 Verticillium dahliae 34.58 2.00e-31 129.00
IUUC-Vpa-130329 Vicugna pacos 48.10 5.00e-15 76.30
IUUC-Vvi-131178 Vitis vinifera 40.53 6.00e-36 144.00
IUUC-Xtr-132139 Xenopus tropicalis 69.00 3.00e-94 337.00
IUUC-Xma-134015 Xiphophorus maculatus 59.26 2.00e-80 291.00
IUUC-Yli-134439 Yarrowia lipolytica 38.46 4.00e-33 134.00
IUUC-Zma-135720 Zea mays 37.28 2.00e-27 115.00
Created Date 25-Jun-2017

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