iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
miRNAMap	RAID2
Protein-protein Interaction
IID
Post-translational Modifications (PTMs)
dbPAF	PhosphositePlus
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.10e-40	136.3	588	626
UBD/Beta-Prp	6.50e-94	314.8	549	706

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ +v c++  +d  l+++Gs D ++k+W l+ g++ +
   Q: 588  GHKLPVICMDIsHDgALIATGSADRNVKIWGLDFGDCHR 626
           7999999**99977799*******************977 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkllrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvl 98
           ++v++ v++spd++lla++  d t+k++ v+t k++ sl+gh+ +v ++++s+dg +++tgs Dr++k+w l+ g+c ++l +h+dsv+
   Q: 549  EDVLY-VCYSPDQRLLAVSLLDCTVKIFYVDTLKFFLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHRSLFAHDDSVM 636
           56788.9********************************************************************************** PP
   S: 99   slsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGslDrtvrlWdlktg 169
            l+f p+++ + ++++d  i+ wd ++ + ++ tl+gh++ ++c++v+p+g+++vs+s D+ +rlW   ++
   Q: 637  HLRFVPKSHLFFTAGKDHKIKQWDADKFEHIQ-TLEGHHQEIWCLAVSPSGDYVVSASHDKSLRLWERTRE 706
           ********************************.*********************************98555 PP

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MGLTKQYLRY VASAVFGLIG SQKGNIVFVT LRGEKGRYVA VPACEHVFIW DLRKGEKILI 60
LQGLKQEVTC LCPSPDGLHL AVGYEDGAIR VFSLLSGEGN ITFNGHRAAV TSLKYDQLGG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

GGGGCGGGTC CGGCTGGCGG TGCTGTCTGC TGGAACCTCG TGGAGGCTGA GGTGAGTGTT 60
TATGACTGTT TAGGGATCGT GAGACGCGGT TCCCCGCACT GTGGTGTTCA CAGGGCCGAC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR011047--Quinoprotein_ADH-like_supfam
IPR007148--SSU_processome_Utp12
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF04003--Utp12
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0031965--C:nuclear membrane
GO:0034388--C:Pwp2p-containing subcomplex of 90S preribosome
GO:0032040--C:small-subunit processome
GO:0030515--F:snoRNA binding
GO:0000462--P:maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

KEGG

rno:310720

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000784	Aegilops tauschii	37.49	9.00e-149	521.00
IUUC-Aml-001245	Ailuropoda melanoleuca	89.62	0.00e+00	1600.00
IUUC-Atr-002700	Amborella trichopoda	37.67	2.00e-166	579.00
IUUC-Apl-004164	Anas platyrhynchos	76.15	0.00e+00	1049.00
IUUC-Aca-004765	Anolis carolinensis	72.69	0.00e+00	1357.00
IUUC-Aly-006503	Arabidopsis lyrata	39.17	2.00e-173	602.00
IUUC-Ath-006848	Arabidopsis thaliana	38.49	9.00e-176	610.00
IUUC-Ago-007909	Ashbya gossypii	34.83	2.00e-144	506.00
IUUC-Acl-008238	Aspergillus clavatus	38.87	8.00e-179	620.00
IUUC-Afl-008544	Aspergillus flavus	39.60	6.00e-177	614.00
IUUC-Afu-008868	Aspergillus fumigatus	38.76	5.00e-178	618.00
IUUC-Ani-009367	Aspergillus nidulans	39.06	2.00e-173	603.00
IUUC-Ang-009732	Aspergillus niger	38.63	1.00e-178	620.00
IUUC-Aor-010140	Aspergillus oryzae	39.67	2.00e-177	616.00
IUUC-Ate-010572	Aspergillus terreus	38.77	1.00e-175	610.00
IUUC-Ame-010956	Astyanax mexicanus	72.88	0.00e+00	803.00
IUUC-Bgr-012296	Blumeria graminis	37.26	1.00e-170	593.00
IUUC-Bta-012716	Bos taurus	90.15	0.00e+00	1614.00
IUUC-Bci-013699	Botrytis cinerea	36.75	7.00e-162	564.00
IUUC-Bdi-014525	Brachypodium distachyon	36.79	1.00e-156	547.00
IUUC-Bol-015117	Brassica oleracea	38.52	9.00e-171	594.00
IUUC-Bra-016869	Brassica rapa	38.08	5.00e-171	595.00
IUUC-Cel-018570	Caenorhabditis elegans	34.39	4.00e-130	459.00
IUUC-Cja-019425	Callithrix jacchus	89.32	0.00e+00	1601.00
IUUC-Cfa-020787	Canis familiaris	88.98	0.00e+00	1602.00
IUUC-Cpo-021729	Cavia porcellus	90.44	0.00e+00	1141.00
IUUC-Cre-022678	Chlamydomonas reinhardtii	43.20	4.00e-105	375.00
IUUC-Csa-024098	Chlorocebus sabaeus	90.36	0.00e+00	1615.00
IUUC-Cho-024495	Choloepus hoffmanni	74.60	0.00e+00	861.00
IUUC-Cin-025245	Ciona intestinalis	49.06	1.00e-167	582.00
IUUC-Cgl-026708	Colletotrichum gloeosporioides	38.12	2.00e-163	570.00
IUUC-Cne-026835	Cryptococcus neoformans	44.86	3.00e-122	432.00
IUUC-Cme-027162	Cyanidioschyzon merolae	29.27	6.00e-40	159.00
IUUC-Dre-027874	Danio rerio	69.21	0.00e+00	1261.00
IUUC-Dno-028905	Dasypus novemcinctus	88.77	0.00e+00	1602.00
IUUC-Dor-030383	Dipodomys ordii	87.63	0.00e+00	810.00
IUUC-Dse-031297	Dothistroma septosporum	36.67	1.00e-163	570.00
IUUC-Dme-031956	Drosophila melanogaster	41.68	0.00e+00	660.00
IUUC-Ete-032608	Echinops telfairi	78.97	0.00e+00	870.00
IUUC-Eca-034181	Equus caballus	89.51	0.00e+00	1579.00
IUUC-Eeu-034495	Erinaceus europaeus	88.80	0.00e+00	1531.00
IUUC-Fca-035994	Felis catus	89.66	0.00e+00	1502.00
IUUC-Fal-036611	Ficedula albicollis	75.90	0.00e+00	1318.00
IUUC-Fox-037807	Fusarium oxysporum	37.24	1.00e-167	583.00
IUUC-Fso-038090	Fusarium solani	37.41	1.00e-163	570.00
IUUC-Gmo-039018	Gadus morhua	62.94	0.00e+00	692.00
IUUC-Ggr-039748	Gaeumannomyces graminis	37.95	5.00e-171	595.00
IUUC-Gga-040707	Gallus gallus	75.56	0.00e+00	1323.00
IUUC-Gac-042334	Gasterosteus aculeatus	63.54	0.00e+00	682.00
IUUC-Gma-043860	Glycine max	37.41	3.00e-167	582.00
IUUC-Ggo-045334	Gorilla gorilla	89.01	0.00e+00	1574.00
IUUC-Hsa-046996	Homo sapiens	90.36	0.00e+00	1576.00
IUUC-Hvu-047381	Hordeum vulgare	34.00	8.00e-87	314.00
IUUC-Itr-047938	Ictidomys tridecemlineatus	89.94	0.00e+00	1590.00
IUUC-Kpa-049185	Komagataella pastoris	34.15	2.00e-145	509.00
IUUC-Lch-050098	Latimeria chalumnae	66.52	0.00e+00	1126.00
IUUC-Lpe-050710	Leersia perrieri	36.06	2.00e-159	556.00
IUUC-Loc-052745	Lepisosteus oculatus	67.67	0.00e+00	1167.00
IUUC-Lma-053104	Leptosphaeria maculans	38.41	2.00e-175	610.00
IUUC-Laf-054395	Loxodonta africana	87.71	0.00e+00	1560.00
IUUC-Mcc-055077	Macaca mulatta	90.36	0.00e+00	1608.00
IUUC-Meu-056418	Macropus eugenii	79.53	0.00e+00	712.00
IUUC-Mor-057031	Magnaporthe oryzae	37.56	8.00e-154	538.00
IUUC-Mpo-057420	Magnaporthe poae	38.39	7.00e-168	584.00
IUUC-Mtr-057838	Medicago truncatula	37.80	2.00e-177	616.00
IUUC-Mla-058854	Melampsora laricipopulina	36.77	1.00e-154	540.00
IUUC-Mga-060120	Meleagris gallopavo	71.44	0.00e+00	1223.00
IUUC-Mvi-060407	Microbotryum violaceum	45.17	4.00e-135	476.00
IUUC-Mmr-060635	Microcebus murinus	88.55	0.00e+00	1570.00
IUUC-Mdo-063023	Monodelphis domestica	83.56	0.00e+00	1531.00
IUUC-Mmu-064103	Mus musculus	96.07	0.00e+00	1724.00
IUUC-Mac-065569	Musa acuminata	37.81	2.00e-168	586.00
IUUC-Mpu-066462	Mustela putorius furo	89.94	0.00e+00	1615.00
IUUC-Mlu-067894	Myotis lucifugus	89.62	0.00e+00	1616.00
IUUC-Nfi-068321	Neosartorya fischeri	38.89	6.00e-177	614.00
IUUC-Ncr-068661	Neurospora crassa	37.13	1.00e-165	577.00
IUUC-Nle-069409	Nomascus leucogenys	90.04	0.00e+00	1580.00
IUUC-Opr-070445	Ochotona princeps	85.62	0.00e+00	966.00
IUUC-Ont-072339	Oreochromis niloticus	68.83	0.00e+00	1224.00
IUUC-Oan-073688	Ornithorhynchus anatinus	75.16	0.00e+00	1330.00
IUUC-Ocu-074227	Oryctolagus cuniculus	89.83	0.00e+00	1626.00
IUUC-Oba-075635	Oryza barthii	36.18	6.00e-153	535.00
IUUC-Obr-076897	Oryza brachyantha	37.34	2.00e-164	573.00
IUUC-Ogl-077555	Oryza glaberrima	36.08	1.00e-152	533.00
IUUC-Ogu-078724	Oryza glumaepatula	36.08	2.00e-153	536.00
IUUC-Oin-080030	Oryza indica	36.18	6.00e-153	535.00
IUUC-Olo-080687	Oryza longistaminata	34.35	2.00e-141	497.00
IUUC-Ome-081867	Oryza meridionalis	36.60	3.00e-155	542.00
IUUC-Oni-082559	Oryza nivara	36.18	6.00e-153	535.00
IUUC-Opu-083332	Oryza punctata	38.76	1.00e-144	507.00
IUUC-Oru-084455	Oryza rufipogon	36.18	5.00e-153	535.00
IUUC-Osa-085793	Oryza sativa	36.18	5.00e-153	535.00
IUUC-Ola-087395	Oryzias latipes	67.82	0.00e+00	1135.00
IUUC-Olu-087768	Ostreococcus lucimarinus	36.79	8.00e-150	524.00
IUUC-Oga-088574	Otolemur garnettii	89.62	0.00e+00	1613.00
IUUC-Oar-089453	Ovis aries	88.48	0.00e+00	1603.00
IUUC-Ptr-090694	Pan troglodytes	90.47	0.00e+00	1575.00
IUUC-Pan-092420	Papio anubis	90.06	0.00e+00	1600.00
IUUC-Psi-093683	Pelodiscus sinensis	80.55	0.00e+00	1430.00
IUUC-Pma-094197	Petromyzon marinus	57.46	6.00e-72	263.00
IUUC-Pno-094783	Phaeosphaeria nodorum	38.01	6.00e-174	604.00
IUUC-Ppa-095208	Physcomitrella patens	39.68	2.00e-170	593.00
IUUC-Pfo-096299	Poecilia formosa	67.72	0.00e+00	1229.00
IUUC-Pab-098706	Pongo abelii	90.24	0.00e+00	1582.00
IUUC-Pop-099275	Populus trichocarpa	38.47	1.00e-169	590.00
IUUC-Pca-100796	Procavia capensis	74.08	0.00e+00	1172.00
IUUC-Ppe-101861	Prunus persica	39.47	1.00e-177	617.00
IUUC-Pva-103241	Pteropus vampyrus	83.65	0.00e+00	1432.00
IUUC-Pgr-103432	Puccinia graminis	40.31	3.00e-115	409.00
IUUC-Ptt-103742	Puccinia triticina	39.51	2.00e-99	357.00
IUUC-Pte-104069	Pyrenophora teres	37.67	1.00e-164	573.00
IUUC-Pyt-104650	Pyrenophora triticirepentis	37.57	3.00e-171	595.00
IUUC-Sce-106271	Saccharomyces cerevisiae	36.12	5.00e-155	541.00
IUUC-Sha-107550	Sarcophilus harrisii	83.98	0.00e+00	1523.00
IUUC-Sja-107664	Schizosaccharomyces japonicus	37.95	7.00e-160	558.00
IUUC-Spo-108239	Schizosaccharomyces pombe	38.09	3.00e-168	585.00
IUUC-Ssl-108626	Sclerotinia sclerotiorum	37.66	7.00e-168	584.00
IUUC-Smo-109477	Selaginella moellendorffii	38.63	4.00e-166	578.00
IUUC-Sit-110000	Setaria italica	37.81	5.00e-155	541.00
IUUC-Sly-111595	Solanum lycopersicum	37.79	4.00e-176	612.00
IUUC-Stu-112516	Solanum tuberosum	37.87	2.00e-176	613.00
IUUC-Sar-113195	Sorex araneus	80.27	0.00e+00	1269.00
IUUC-Sbi-114465	Sorghum bicolor	36.75	2.00e-163	569.00
IUUC-Sre-115006	Sporisorium reilianum	34.55	6.00e-142	498.00
IUUC-Ssc-115929	Sus scrofa	88.67	0.00e+00	1565.00
IUUC-Tgu-117282	Taeniopygia guttata	75.79	0.00e+00	1311.00
IUUC-Tru-118406	Takifugu rubripes	67.24	0.00e+00	1177.00
IUUC-Tsy-119170	Tarsius syrichta	88.04	0.00e+00	1590.00
IUUC-Tni-119721	Tetraodon nigroviridis	66.45	0.00e+00	1150.00
IUUC-Tca-121761	Theobroma cacao	38.25	5.00e-177	614.00
IUUC-Tre-121908	Trichoderma reesei	36.11	3.00e-161	562.00
IUUC-Tvi-122547	Trichoderma virens	36.85	7.00e-165	574.00
IUUC-Tae-125496	Triticum aestivum	37.11	2.00e-160	560.00
IUUC-Tur-126811	Triticum urartu	38.25	5.00e-160	558.00
IUUC-Tme-126987	Tuber melanosporum	39.32	8.00e-175	607.00
IUUC-Tbe-127315	Tupaia belangeri	90.20	0.00e+00	842.00
IUUC-Ttr-129165	Tursiops truncatus	80.72	0.00e+00	1375.00
IUUC-Uma-129651	Ustilago maydis	34.73	1.00e-144	507.00
IUUC-Vda-129973	Verticillium dahliae	38.13	1.00e-161	564.00
IUUC-Vpa-130163	Vicugna pacos	78.32	0.00e+00	689.00
IUUC-Vvi-131402	Vitis vinifera	36.32	4.00e-172	598.00
IUUC-Xtr-132296	Xenopus tropicalis	71.84	0.00e+00	1265.00
IUUC-Xma-133028	Xiphophorus maculatus	68.01	0.00e+00	1235.00
IUUC-Yli-134484	Yarrowia lipolytica	37.83	4.00e-152	532.00
IUUC-Zma-135938	Zea mays	36.13	3.00e-160	559.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence