iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Pan-091692

Ensembl Protein ID

ENSPANP00000012766.1

UniProt Accession

A0A096NIG8; A0A096NIG8_PAPAN

Genbank Protein ID

ENSPANP00000012766

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AHZZ01049876

Gene Name

AMFR

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSPANG00000015100.1	ENSPANT00000015074.1	ENSPANP00000012766.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RING/RING	1.90e-09	38.0	341	379
UBD/Alpha-Helix/CUE	1.50e-10	40.9	455	495

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RING/RING

   S: 1    CaiCledfkdgplvlpCgHvfhadClqkwpglknssskefrCPlCr 46
           CaiC+++++   + lpCgH+fh +Cl  w        +  +CP+Cr
   Q: 341  CAICWDSMQA-ARKLPCGHLFHNSCLRSW------LEQDTSCPTCR 379
           ********99.******************......9*********8 PP

UBD/Alpha-Helix/CUE

   S: 2    letaleqLkeiFPnldysviqvvLeantgsleaavnnLLegs 43
           l+++++q++e+FP+++y ++ ++L ++t s+e +++n+Leg 
   Q: 455  LNSLAHQIQEMFPQVPYHLVLQDL-QLTRSVEITTDNILEGR 495
           67899*******************.***************95 PP

Organism

Papio anubis

Protein Sequence
(Fasta)

MPLLFLERFP WPSLRTYTGL SGLALLGTII SAYRALSQPE VGPGEPDQLT ASLQPEPPAP 60
ARPSAGGPRA RDVAQYLLSD SLFVWVVVNT ACCVLMLVAK LIQCIVFGPL RVSERQHLKD 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CGCCGAGGCT CTTCCGCGCC GGCAGGGGCA GCAGCGGGAG CGGCGCGTGG CGGAGCGGCG 60
CCATCAGCCA GGATCGGTCC GGCCCGGCCC GGCGCGGCTG CGTCGGCGGC GGCGGCGGCG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-1185--Reference proteome
KW-0812--Transmembrane
KW-1133--Transmembrane helix

Interpro

IPR003892--CUE
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS51140--CUE
PS50089--ZF_RING_2

Pfam

PF02845--CUE
PF13639--zf-RING_2

SMART

SM00546--CUE
SM00184--RING

Gene Ontology

GO:0036513--C:Derlin-1 retrotranslocation complex
GO:0005794--C:Golgi apparatus
GO:0030176--C:integral component of endoplasmic reticulum membrane
GO:0048471--C:perinuclear region of cytoplasm
GO:0004872--F:receptor activity
GO:0034450--F:ubiquitin-ubiquitin ligase activity
GO:0008270--F:zinc ion binding
GO:0030968--P:endoplasmic reticulum unfolded protein response
GO:0032092--P:positive regulation of protein binding
GO:0051865--P:protein autoubiquitination
GO:0070936--P:protein K48-linked ubiquitination
GO:0051259--P:protein oligomerization
GO:0030433--P:ubiquitin-dependent ERAD pathway

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001300	Ailuropoda melanoleuca	89.41	0.00e+00	959.00
IUUC-Apl-003404	Anas platyrhynchos	83.63	0.00e+00	875.00
IUUC-Aca-004559	Anolis carolinensis	81.13	0.00e+00	812.00
IUUC-Ame-011640	Astyanax mexicanus	67.61	0.00e+00	776.00
IUUC-Bta-012980	Bos taurus	84.21	0.00e+00	1013.00
IUUC-Cel-018598	Caenorhabditis elegans	24.88	4.00e-33	135.00
IUUC-Cja-019577	Callithrix jacchus	93.47	0.00e+00	1157.00
IUUC-Cfa-020793	Canis familiaris	90.00	0.00e+00	947.00
IUUC-Cpo-022387	Cavia porcellus	91.45	0.00e+00	1121.00
IUUC-Csa-023168	Chlorocebus sabaeus	95.33	0.00e+00	1180.00
IUUC-Cho-024433	Choloepus hoffmanni	91.02	0.00e+00	781.00
IUUC-Cin-025215	Ciona intestinalis	42.51	3.00e-138	485.00
IUUC-Csv-026133	Ciona savignyi	45.26	4.00e-122	431.00
IUUC-Dre-027594	Danio rerio	65.13	0.00e+00	727.00
IUUC-Dno-029407	Dasypus novemcinctus	92.47	0.00e+00	957.00
IUUC-Dor-030961	Dipodomys ordii	92.46	0.00e+00	988.00
IUUC-Ete-032962	Echinops telfairi	86.20	0.00e+00	857.00
IUUC-Eca-033683	Equus caballus	85.56	0.00e+00	1007.00
IUUC-Eeu-034515	Erinaceus europaeus	80.74	1.00e-61	230.00
IUUC-Fca-035398	Felis catus	90.82	0.00e+00	916.00
IUUC-Fal-036758	Ficedula albicollis	95.15	2.00e-179	622.00
IUUC-Gmo-039014	Gadus morhua	64.93	0.00e+00	712.00
IUUC-Gga-040575	Gallus gallus	81.03	0.00e+00	949.00
IUUC-Gac-041414	Gasterosteus aculeatus	64.16	0.00e+00	693.00
IUUC-Hsa-046272	Homo sapiens	95.33	0.00e+00	1136.00
IUUC-Itr-047956	Ictidomys tridecemlineatus	91.28	0.00e+00	970.00
IUUC-Lch-050491	Latimeria chalumnae	72.23	0.00e+00	805.00
IUUC-Loc-052758	Lepisosteus oculatus	71.95	0.00e+00	780.00
IUUC-Laf-053452	Loxodonta africana	92.32	0.00e+00	970.00
IUUC-Mcc-055820	Macaca mulatta	94.89	0.00e+00	989.00
IUUC-Meu-056726	Macropus eugenii	84.83	0.00e+00	857.00
IUUC-Mga-059937	Meleagris gallopavo	82.19	0.00e+00	893.00
IUUC-Mmr-060730	Microcebus murinus	89.11	0.00e+00	1082.00
IUUC-Mdo-062771	Monodelphis domestica	85.10	0.00e+00	1008.00
IUUC-Mmu-064219	Mus musculus	90.37	0.00e+00	1113.00
IUUC-Mpu-066796	Mustela putorius furo	91.06	0.00e+00	954.00
IUUC-Mlu-068189	Myotis lucifugus	89.51	0.00e+00	945.00
IUUC-Nle-069239	Nomascus leucogenys	94.83	0.00e+00	1126.00
IUUC-Opr-070702	Ochotona princeps	81.88	5.00e-123	434.00
IUUC-Ont-072033	Oreochromis niloticus	67.00	0.00e+00	756.00
IUUC-Oan-073717	Ornithorhynchus anatinus	80.89	0.00e+00	808.00
IUUC-Ocu-074145	Oryctolagus cuniculus	89.42	0.00e+00	1090.00
IUUC-Ogl-077929	Oryza glaberrima	53.49	1.00e-11	62.40
IUUC-Ola-087152	Oryzias latipes	65.64	0.00e+00	742.00
IUUC-Oga-088486	Otolemur garnettii	92.72	0.00e+00	983.00
IUUC-Oar-089310	Ovis aries	90.71	0.00e+00	978.00
IUUC-Ptr-090649	Pan troglodytes	94.80	0.00e+00	1008.00
IUUC-Psi-093064	Pelodiscus sinensis	88.69	0.00e+00	716.00
IUUC-Pma-094763	Petromyzon marinus	77.05	8.00e-97	346.00
IUUC-Ppa-095969	Physcomitrella patens	29.91	6.00e-36	145.00
IUUC-Pfo-096810	Poecilia formosa	65.90	0.00e+00	741.00
IUUC-Pab-097859	Pongo abelii	94.89	0.00e+00	991.00
IUUC-Pop-099576	Populus trichocarpa	27.06	2.00e-28	120.00
IUUC-Pca-100344	Procavia capensis	88.84	0.00e+00	1038.00
IUUC-Pva-103114	Pteropus vampyrus	67.03	0.00e+00	709.00
IUUC-Rno-105880	Rattus norvegicus	88.34	0.00e+00	1062.00
IUUC-Sha-107015	Sarcophilus harrisii	88.61	0.00e+00	926.00
IUUC-Smo-109664	Selaginella moellendorffii	30.92	3.00e-33	136.00
IUUC-Sar-113397	Sorex araneus	91.91	0.00e+00	706.00
IUUC-Ssc-115988	Sus scrofa	83.68	4.00e-124	437.00
IUUC-Tgu-116717	Taeniopygia guttata	85.04	0.00e+00	884.00
IUUC-Tru-117805	Takifugu rubripes	65.02	0.00e+00	763.00
IUUC-Tsy-119442	Tarsius syrichta	89.61	0.00e+00	937.00
IUUC-Tni-119777	Tetraodon nigroviridis	67.36	2.00e-152	532.00
IUUC-Tbe-127322	Tupaia belangeri	68.67	2.00e-115	409.00
IUUC-Ttr-128181	Tursiops truncatus	90.14	0.00e+00	973.00
IUUC-Vpa-130483	Vicugna pacos	84.05	0.00e+00	656.00
IUUC-Xtr-132614	Xenopus tropicalis	72.82	0.00e+00	737.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence