iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO
DNA & RNA Element
microRNA	miRNAMap	RAID2
Protein-protein Interaction
iRefIndex	PINA	Mentha
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	1.50e-15	57.0	311	343

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 2    Htdsvtclaf..sd.tllvsGsdDgtikvWDlr 31
           Ht++v+++a+  ++ +++++++dD +  +WDl 
   Q: 311  HTGPVNGIAWapHSpHHICTAGDDSQALIWDLQ 343
           ***********733699**************85 PP

Organism

Caenorhabditis elegans

Protein Sequence
(Fasta)

MATNGHAVNG EAHVMQQVAQ QPAPPGPLAP QGIGRQNEIV IGGRDRRCEI YKFTSDQQLY 60
ASAWSNKNDI KFRLAVGTVS DVSVNPCAAN KVSIVQLKDE TGELVETASF PMEFPANAVG 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AAACTTGTGA ACCCTTATCA CCTGCAATGG CTACCAATGG TCACGCAGTG AACGGAGAAG 60
CTCATGTTAT GCAACAAGTC GCACAACAAC CAGCTCCACC AGGACCATTA GCTCCGCAAG 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1267--Proteomics identification
KW-1185--Reference proteome
KW-0853--WD repeat

Interpro

IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0005737--C:cytoplasm
GO:0005634--C:nucleus
GO:0030274--F:LIM domain binding
GO:0048365--F:Rac GTPase binding
GO:0030336--P:negative regulation of cell migration
GO:0060101--P:negative regulation of phagocytosis, engulfment
GO:0030516--P:regulation of axon extension
GO:0043087--P:regulation of GTPase activity
GO:0009408--P:response to heat
GO:0006970--P:response to osmotic stress

KEGG

cel:CELE_F53C11.8

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence