iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

UUCD2 ID

IUUC-Aca-004252

UUCD1 version

UUC-AnC-00203

Ensembl Protein ID

ENSACAP00000016134.3

UniProt Accession

H9GN76; H9GN76_ANOCA

Protein Name

Uncharacterized protein

Gene Name

RNF19A

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSACAG00000016401.3	ENSACAT00000016455.3	ENSACAP00000016134.3

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 activity/RBR	4.50e-52	177.4	113	313

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 activity/RBR

   S: 1    CkvCllelsveeltvlleCehtfCkeClkqylelkikegqvteiscpaaecpekleeseikellveeelykryekllleevveadaalkw 90
           C++Cll++s+e+++ +++C+h+ C +Cl+qyl+++i+e++ ++iscp  ec+e++++++i+ +l ++ l+++ye+++l++++ ad++++w
   Q: 113  CPLCLLRHSKERFPEIMTCHHRSCVDCLRQYLRIEISESR-VNISCP--ECSERFNPHDIRLILNDDILMEKYEEFMLRRWLVADPDCRW 199
           ****************************************.9*****..89*************************************** PP
   S: 91   cpapdCslvvllekea..eklevecekcgkefCveCkeewHeglsCkelkeklakteeek.......eeaeskelleanskkCpkCkvyi 171
           cpapdC ++v++  +a  +kl++ +e+c++efC++Ck++wH++++C+++++++a++ + +       + ++++ ++++++k+Cp+C +yi
   Q: 200  CPAPDCGYAVIAFGCAscPKLTCGREGCETEFCYHCKQIWHPNQTCDAARQERAQSLRLRtirsssiSYSQESGAAADDIKPCPRCAAYI 289
           *************999889************************************99998999*99999999****************** PP
   S: 172  ek..negCnhmtCakCkaefCwlC 193
           +k  +++CnhmtCa C++efCwlC
   Q: 290  IKmnDGSCNHMTCAVCGCEFCWLC 313
           *997889***************** PP

Organism

Anolis carolinensis

Protein Sequence
(Fasta)

MCFDQFLMNI LAMSLHRQMG SDRDLQSSAS SVSLPSIKKA PKKRRISLGS LFRRKRDTKR 60
KSRDINGGVD GIASIETIHS EMCTDKNSFF SAYMSPENGA NICSKQSGDF MECPLCLLRH 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

AATCTTTGAA GAATCCCTGG AATTACATGC TGTGAAGAAT TTTGTGCATA TACAAGTATG 60
ACCTGATGAT GCCTAAAATG ACTTCAACCC ACCTTTCAGG ATAACCTGAA TATGCTGCTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0472--Membrane
KW-0479--Metal-binding
KW-1185--Reference proteome
KW-0677--Repeat
KW-0808--Transferase
KW-0812--Transmembrane
KW-1133--Transmembrane helix
KW-0862--Zinc
KW-0863--Zinc-finger

Interpro

IPR016150--Casein_kin_II_reg-sub_b-sht
IPR031127--E3_UB_ligase_RBR
IPR002867--IBR_dom
IPR001841--Znf_RING
IPR013083--Znf_RING/FYVE/PHD

PROSITE

PS50089--ZF_RING_2

Pfam

PF01485--IBR

SMART

SM00647--IBR
SM00184--RING

Gene Ontology

GO:0005813--C:centrosome
GO:0005737--C:cytoplasm
GO:0016021--C:integral component of membrane
GO:0000151--C:ubiquitin ligase complex
GO:0031624--F:ubiquitin conjugating enzyme binding
GO:0061630--F:ubiquitin protein ligase activity
GO:0008270--F:zinc ion binding
GO:0032436--P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0000209--P:protein polyubiquitination
GO:0042787--P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001958	Ailuropoda melanoleuca	86.95	0.00e+00	1182.00
IUUC-Apl-003427	Anas platyrhynchos	91.55	0.00e+00	1179.00
IUUC-Ame-011434	Astyanax mexicanus	74.43	0.00e+00	871.00
IUUC-Bta-013558	Bos taurus	87.20	0.00e+00	1186.00
IUUC-Cel-018626	Caenorhabditis elegans	53.93	2.00e-111	397.00
IUUC-Cja-019070	Callithrix jacchus	87.20	0.00e+00	1186.00
IUUC-Cfa-020286	Canis familiaris	86.95	0.00e+00	1182.00
IUUC-Cpo-022015	Cavia porcellus	86.95	0.00e+00	1177.00
IUUC-Csa-023975	Chlorocebus sabaeus	87.68	0.00e+00	1172.00
IUUC-Cho-024442	Choloepus hoffmanni	73.29	0.00e+00	967.00
IUUC-Dre-028422	Danio rerio	75.51	0.00e+00	887.00
IUUC-Dno-029018	Dasypus novemcinctus	87.03	0.00e+00	1144.00
IUUC-Dor-030548	Dipodomys ordii	80.67	2.00e-152	533.00
IUUC-Eca-034249	Equus caballus	87.68	0.00e+00	1194.00
IUUC-Eeu-035298	Erinaceus europaeus	92.29	0.00e+00	763.00
IUUC-Fca-035912	Felis catus	87.07	0.00e+00	1184.00
IUUC-Fal-037488	Ficedula albicollis	88.56	0.00e+00	1138.00
IUUC-Gmo-038893	Gadus morhua	81.66	0.00e+00	791.00
IUUC-Gga-040380	Gallus gallus	90.37	0.00e+00	1142.00
IUUC-Gac-041421	Gasterosteus aculeatus	75.41	0.00e+00	880.00
IUUC-Ggo-044893	Gorilla gorilla	87.29	0.00e+00	1184.00
IUUC-Hsa-046876	Homo sapiens	87.41	0.00e+00	1185.00
IUUC-Itr-048257	Ictidomys tridecemlineatus	87.07	0.00e+00	1181.00
IUUC-Lch-049774	Latimeria chalumnae	85.91	0.00e+00	1114.00
IUUC-Loc-052040	Lepisosteus oculatus	79.69	0.00e+00	982.00
IUUC-Laf-053874	Loxodonta africana	87.32	0.00e+00	1166.00
IUUC-Mcc-054817	Macaca mulatta	86.21	9.00e-88	315.00
IUUC-Meu-056648	Macropus eugenii	90.67	1.00e-165	576.00
IUUC-Mla-059062	Melampsora laricipopulina	25.00	9.00e-11	61.20
IUUC-Mga-060175	Meleagris gallopavo	90.49	0.00e+00	1161.00
IUUC-Mmr-060800	Microcebus murinus	87.56	0.00e+00	1191.00
IUUC-Mdo-061827	Monodelphis domestica	87.13	0.00e+00	1093.00
IUUC-Mmu-064134	Mus musculus	84.83	0.00e+00	1118.00
IUUC-Mpu-066076	Mustela putorius furo	87.07	0.00e+00	1185.00
IUUC-Mlu-068218	Myotis lucifugus	86.26	0.00e+00	1117.00
IUUC-Nle-069707	Nomascus leucogenys	92.28	0.00e+00	979.00
IUUC-Opr-070977	Ochotona princeps	86.59	0.00e+00	1189.00
IUUC-Ont-072373	Oreochromis niloticus	76.73	0.00e+00	934.00
IUUC-Oan-073376	Ornithorhynchus anatinus	89.63	1.00e-167	582.00
IUUC-Ocu-074878	Oryctolagus cuniculus	86.34	0.00e+00	1154.00
IUUC-Ola-086472	Oryzias latipes	78.36	0.00e+00	912.00
IUUC-Oga-088377	Otolemur garnettii	87.32	0.00e+00	1181.00
IUUC-Oar-089540	Ovis aries	86.95	0.00e+00	1181.00
IUUC-Ptr-090613	Pan troglodytes	87.41	0.00e+00	1185.00
IUUC-Pan-092879	Papio anubis	87.80	0.00e+00	1174.00
IUUC-Psi-093201	Pelodiscus sinensis	90.88	0.00e+00	1159.00
IUUC-Pma-094620	Petromyzon marinus	71.75	0.00e+00	799.00
IUUC-Pfo-096615	Poecilia formosa	82.50	0.00e+00	875.00
IUUC-Pca-100625	Procavia capensis	86.34	0.00e+00	1150.00
IUUC-Pva-103110	Pteropus vampyrus	80.00	0.00e+00	938.00
IUUC-Rno-105998	Rattus norvegicus	84.85	0.00e+00	1126.00
IUUC-Sha-107523	Sarcophilus harrisii	86.36	0.00e+00	1083.00
IUUC-Sar-113089	Sorex araneus	83.47	0.00e+00	845.00
IUUC-Ssc-115471	Sus scrofa	86.83	0.00e+00	1150.00
IUUC-Tgu-117080	Taeniopygia guttata	89.42	0.00e+00	1171.00
IUUC-Tru-117547	Takifugu rubripes	79.03	0.00e+00	880.00
IUUC-Tsy-119143	Tarsius syrichta	85.61	0.00e+00	1162.00
IUUC-Tni-119693	Tetraodon nigroviridis	73.67	0.00e+00	877.00
IUUC-Ttr-129175	Tursiops truncatus	86.59	0.00e+00	1169.00
IUUC-Vpa-130594	Vicugna pacos	80.22	0.00e+00	1089.00
IUUC-Xtr-132579	Xenopus tropicalis	87.61	0.00e+00	1123.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence