iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Fal-037634

Ensembl Protein ID

ENSFALP00000009135.1

UniProt Accession

U3K281; U3K281_FICAL

Genbank Protein ID

ENSFALP00000009135

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AGTO01021123

Gene Name

USP4

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSFALG00000008747.1	ENSFALT00000009174.1	ENSFALP00000009135.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
DUB/USP	1.20e-116	389.2	303	919
ULD/UDP/UBQ/UBQ_Other	5.00e-14	51.6	143	221

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

DUB/USP

   S: 1    tGlkNlgNtCYmNSvLQcLsnipelrellle.kkkeklneenpkepkgellkslqklfeelwkskkkavsprellkalkkeaeefsgye 88
           +Gl+NlgNtC+mNS+LQcLsn+p+l++++le k++ ++n++np ++ ge+++++++l++++w++++++v+pr+++++++++a++fsgy+
   Q: 303  CGLSNLGNTCFMNSALQCLSNTPPLTDYFLEdKYEAEINQNNPLGMRGEIAEAYADLIKQMWSGRQSHVAPRMFKTQVGRFAPQFSGYQ 391
           7******************************9********************************************************* PP
   S: 89   qqDaqEflaflldqleeelkkeknkpkeeeeeed...kselsdeaeekkkkknkslisdlFqgqlksqikclecdnvssreepfldlsl 174
           qqD+qE+laflld+l+e+l++ k+kp+ e+++++   +se  +ea+e++  +n+s+i+d+F+g +ks+++c++c +vs++++pf++l+l
   Q: 392  QQDSQELLAFLLDGLHEDLNRVKKKPYLELKDANgrpDSEVAKEAWENHRLRNDSIIVDIFHGLFKSTLVCPKCSKVSVTFDPFCYLTL 480
           ***************************99988771113445555********************************************* PP
   S: 175  pvpgkeetkke.............................................................................. 185
           p+p ++++ +e                                                                              
   Q: 481  PLPLRRDRLMEvtlvyadpqrrpvqyrvvvpmmgaisdlceslsklsgvpaenmvvtdvynhrfhkifqmdeslnhilpkddifvyevc 569
           ***999998889***************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 570  kpsedgseyvtlsiyfrektmrqssntsgtvlfgqpllisvpkhkltvdhlysvvleqisrcvklplaeeystpcpdrgtcngsngvve 658
           ***************************************************************************************** PP
   S: 186  ......................................................................................... 185
                                                                                                    
   Q: 659  gdieemehqdggeegkekvtevdpchsegcmqvesardlqpckkqhftfslvnssgtseinsivegkilklnafsavaidwdsetrrll 747
           ***************************************************************************************** PP
   S: 186  .........................slqdcLesftkeeelegenkyycekckkkqeaekklklkklPevLilhLkRfsfseeqksreki 249
                                     l+dc+e ft+ e+l +++ +yc++ckk+q+a+kk++l++lP++L++hLkRfs++++   r k+
   Q: 748  ydeqeaqafekhgsmlqpqkkkavvALRDCIELFTTMETLGEHDPWYCPNCKKHQQATKKFDLWSLPRILVVHLKRFSYNRY--WRDKL 834
           *****************************************************************************99885..567** PP
   S: 250  nkkvefple.LdlspfctspeekqkekkkYeLiavvvHsGslssGHYvayvknekgk.WllfdDskVtevkeeevleetgstaYvlfYk 336
           ++ vefp++ L++s+f+++p  +   ++ Y+Liav +H+G ++ GHY+ay+kn+ ++ W++fdDs+V++ +e+++++   + aYvlfY+
   Q: 835  DTVVEFPIRgLNMSEFVCDPRAG---SYVYDLIAVSNHYGAMGVGHYTAYAKNKVNDkWYYFDDSSVSVASEDQIVT---KAAYVLFYQ 917
           *******************9988...6**************************65555*******************...********* PP
   S: 337  rr 338
           rr
   Q: 918  RR 919
           96 PP

ULD/UDP/UBQ/UBQ_Other

   S: 5    vksldgs.eltlkvnpsdtVaeLKekiekklgip.peqqrLiyk......GkiL.eddktLadyglkdgstihllekksg 75
           ++s+d   + +++++++dtVa++ ++++k+++ip + + rL+++       + L + d t++d gl +g+++++++k+++
   Q: 143  CESSDPDnVISCHFSKADTVATIEKEMRKLFNIPaEKETRLWNRymsntyEQ-LsKLDSTVQDAGLCQGQVVLIEVKNED 221
           6777888899************************777*****8877776444.46*******************999886 PP

Organism

Ficedula albicollis

Protein Sequence
(Fasta)

PPPPPPRAEL GPLLATALRP GESWYLVESR WFKQWKKYVG FDSWDMFGAG DPNLFPGPVD 60
NAGLFPGPID NSGLFGDPET QSLKEHLIDE LDYVLVPTEA WNKLVAWYGC IDGQKPIVRK 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC CCCCCCCCCC 60
CCCCCCCCCC CGGGCGGAGC TGGGGCCGCT CCTGGCCACG GCCCTCCGGC CCGGCGAGTC 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome

Interpro

IPR006615--Pept_C19_DUSP
IPR001394--Peptidase_C19_UCH
IPR028135--Ub_USP-typ
IPR018200--USP_CS
IPR028889--USP_dom

PROSITE

PS51283--DUSP
PS00972--USP_1
PS00973--USP_2
PS50235--USP_3

Pfam

PF06337--DUSP
PF14836--Ubiquitin_3
PF00443--UCH

SMART

SM00695--DUSP

Gene Ontology

GO:0005829--C:cytosol
GO:0005634--C:nucleus
GO:0005886--C:plasma membrane
GO:0004843--F:thiol-dependent ubiquitin-specific protease activity
GO:0031397--P:negative regulation of protein ubiquitination
GO:0016579--P:protein deubiquitination
GO:0034394--P:protein localization to cell surface
GO:0031647--P:regulation of protein stability
GO:0000244--P:spliceosomal tri-snRNP complex assembly
GO:0006511--P:ubiquitin-dependent protein catabolic process

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Ata-000058	Aegilops tauschii	39.53	1.00e-120	427.00
IUUC-Aml-001597	Ailuropoda melanoleuca	73.00	0.00e+00	1330.00
IUUC-Atr-002991	Amborella trichopoda	37.61	6.00e-148	518.00
IUUC-Apl-004068	Anas platyrhynchos	87.07	0.00e+00	1555.00
IUUC-Aca-004459	Anolis carolinensis	74.87	0.00e+00	1332.00
IUUC-Aly-006315	Arabidopsis lyrata	42.58	3.00e-133	469.00
IUUC-Ath-007343	Arabidopsis thaliana	38.24	3.00e-162	565.00
IUUC-Ago-007911	Ashbya gossypii	40.06	6.00e-65	243.00
IUUC-Acl-008284	Aspergillus clavatus	44.77	1.00e-55	212.00
IUUC-Afl-008507	Aspergillus flavus	41.64	6.00e-56	213.00
IUUC-Afu-008878	Aspergillus fumigatus	35.69	4.00e-59	223.00
IUUC-Ani-009479	Aspergillus nidulans	42.37	2.00e-54	208.00
IUUC-Ang-009562	Aspergillus niger	42.41	3.00e-58	221.00
IUUC-Aor-009949	Aspergillus oryzae	34.24	2.00e-55	211.00
IUUC-Ate-010323	Aspergillus terreus	42.81	3.00e-57	217.00
IUUC-Bta-012929	Bos taurus	73.80	0.00e+00	1340.00
IUUC-Bci-013993	Botrytis cinerea	46.59	3.00e-63	237.00
IUUC-Bdi-014013	Brachypodium distachyon	37.81	2.00e-155	543.00
IUUC-Bol-015570	Brassica oleracea	37.79	8.00e-161	560.00
IUUC-Bra-016885	Brassica rapa	36.54	2.00e-158	552.00
IUUC-Cel-018203	Caenorhabditis elegans	52.68	1.00e-70	261.00
IUUC-Cja-018798	Callithrix jacchus	72.06	0.00e+00	1313.00
IUUC-Cfa-020599	Canis familiaris	74.92	0.00e+00	1347.00
IUUC-Cpo-022144	Cavia porcellus	74.31	0.00e+00	1302.00
IUUC-Csa-023770	Chlorocebus sabaeus	75.89	0.00e+00	1258.00
IUUC-Cho-024595	Choloepus hoffmanni	68.57	0.00e+00	848.00
IUUC-Csv-026109	Ciona savignyi	42.27	0.00e+00	678.00
IUUC-Cgl-026741	Colletotrichum gloeosporioides	42.09	3.00e-61	231.00
IUUC-Dno-029316	Dasypus novemcinctus	73.48	0.00e+00	1333.00
IUUC-Dse-031432	Dothistroma septosporum	41.67	3.00e-59	224.00
IUUC-Ete-032970	Echinops telfairi	66.52	0.00e+00	840.00
IUUC-Eca-034012	Equus caballus	74.12	0.00e+00	1312.00
IUUC-Fca-035373	Felis catus	70.40	0.00e+00	1310.00
IUUC-Fox-037986	Fusarium oxysporum	44.85	1.00e-64	241.00
IUUC-Fso-038291	Fusarium solani	42.04	4.00e-67	250.00
IUUC-Gmo-038866	Gadus morhua	63.87	0.00e+00	1107.00
IUUC-Ggr-039740	Gaeumannomyces graminis	44.32	1.00e-63	238.00
IUUC-Gga-040729	Gallus gallus	84.69	0.00e+00	1550.00
IUUC-Gac-042631	Gasterosteus aculeatus	67.19	0.00e+00	1203.00
IUUC-Gma-043077	Glycine max	37.80	1.00e-158	553.00
IUUC-Ggo-045337	Gorilla gorilla	73.70	0.00e+00	1180.00
IUUC-Hsa-045669	Homo sapiens	74.33	0.00e+00	1327.00
IUUC-Hvu-047108	Hordeum vulgare	39.68	3.00e-124	438.00
IUUC-Itr-048610	Ictidomys tridecemlineatus	74.43	0.00e+00	1323.00
IUUC-Lch-050533	Latimeria chalumnae	68.46	0.00e+00	1165.00
IUUC-Lpe-051424	Leersia perrieri	37.42	5.00e-153	535.00
IUUC-Loc-051800	Lepisosteus oculatus	64.62	0.00e+00	1268.00
IUUC-Laf-053803	Loxodonta africana	75.14	0.00e+00	1361.00
IUUC-Mcc-055556	Macaca mulatta	70.66	0.00e+00	1231.00
IUUC-Meu-056742	Macropus eugenii	71.17	0.00e+00	907.00
IUUC-Mor-056985	Magnaporthe oryzae	40.45	1.00e-61	232.00
IUUC-Mpo-057486	Magnaporthe poae	41.46	2.00e-63	238.00
IUUC-Mtr-058138	Medicago truncatula	38.36	4.00e-164	571.00
IUUC-Mga-059300	Meleagris gallopavo	84.44	0.00e+00	1493.00
IUUC-Mdo-061848	Monodelphis domestica	75.88	0.00e+00	1351.00
IUUC-Mmu-063960	Mus musculus	72.24	0.00e+00	1316.00
IUUC-Mac-065239	Musa acuminata	33.47	5.00e-135	475.00
IUUC-Mpu-066920	Mustela putorius furo	73.92	0.00e+00	1345.00
IUUC-Mlu-068088	Myotis lucifugus	73.47	0.00e+00	1324.00
IUUC-Nfi-068330	Neosartorya fischeri	37.78	4.00e-57	217.00
IUUC-Ncr-068879	Neurospora crassa	31.89	9.00e-69	255.00
IUUC-Nle-070010	Nomascus leucogenys	74.54	0.00e+00	1313.00
IUUC-Opr-070740	Ochotona princeps	73.79	0.00e+00	962.00
IUUC-Ont-072573	Oreochromis niloticus	64.72	0.00e+00	1223.00
IUUC-Oan-073363	Ornithorhynchus anatinus	70.27	0.00e+00	1266.00
IUUC-Ocu-074242	Oryctolagus cuniculus	70.45	0.00e+00	1230.00
IUUC-Obr-076902	Oryza brachyantha	38.26	7.00e-151	527.00
IUUC-Ogl-077583	Oryza glaberrima	41.41	2.00e-129	456.00
IUUC-Oin-079300	Oryza indica	41.56	2.00e-130	459.00
IUUC-Opu-083691	Oryza punctata	36.37	1.00e-147	517.00
IUUC-Ola-086553	Oryzias latipes	65.29	0.00e+00	1238.00
IUUC-Olu-087717	Ostreococcus lucimarinus	39.44	7.00e-128	451.00
IUUC-Oga-088562	Otolemur garnettii	68.31	0.00e+00	1180.00
IUUC-Oar-090439	Ovis aries	73.59	0.00e+00	1335.00
IUUC-Ptr-090801	Pan troglodytes	74.30	0.00e+00	1326.00
IUUC-Pan-092717	Papio anubis	70.80	0.00e+00	1212.00
IUUC-Psi-093942	Pelodiscus sinensis	78.70	0.00e+00	1373.00
IUUC-Pno-094890	Phaeosphaeria nodorum	42.45	3.00e-59	224.00
IUUC-Pfo-097060	Poecilia formosa	64.08	0.00e+00	1205.00
IUUC-Pop-099801	Populus trichocarpa	38.74	1.00e-161	563.00
IUUC-Pca-100161	Procavia capensis	67.13	0.00e+00	1137.00
IUUC-Ppe-101587	Prunus persica	38.26	2.00e-155	542.00
IUUC-Rno-106081	Rattus norvegicus	75.14	0.00e+00	1351.00
IUUC-Sha-106937	Sarcophilus harrisii	75.29	0.00e+00	1339.00
IUUC-Spo-108291	Schizosaccharomyces pombe	44.62	2.00e-76	280.00
IUUC-Sit-109948	Setaria italica	36.73	4.00e-143	502.00
IUUC-Sly-111746	Solanum lycopersicum	39.47	7.00e-163	567.00
IUUC-Stu-112671	Solanum tuberosum	39.53	8.00e-163	567.00
IUUC-Sar-113542	Sorex araneus	71.89	0.00e+00	1284.00
IUUC-Sbi-114874	Sorghum bicolor	37.69	4.00e-146	512.00
IUUC-Ssc-115637	Sus scrofa	74.68	0.00e+00	1331.00
IUUC-Tgu-117267	Taeniopygia guttata	91.59	0.00e+00	1657.00
IUUC-Tru-118634	Takifugu rubripes	65.65	0.00e+00	1167.00
IUUC-Tca-121001	Theobroma cacao	38.08	1.00e-160	560.00
IUUC-Tre-121888	Trichoderma reesei	42.65	7.00e-62	233.00
IUUC-Tvi-122422	Trichoderma virens	41.18	2.00e-58	221.00
IUUC-Tae-125295	Triticum aestivum	37.12	3.00e-153	535.00
IUUC-Tur-126392	Triticum urartu	33.33	1.00e-125	443.00
IUUC-Ttr-128778	Tursiops truncatus	73.64	0.00e+00	1314.00
IUUC-Vda-129781	Verticillium dahliae	39.75	2.00e-64	241.00
IUUC-Vvi-131010	Vitis vinifera	39.68	1.00e-156	546.00
IUUC-Xtr-132305	Xenopus tropicalis	67.24	0.00e+00	1249.00
IUUC-Xma-133176	Xiphophorus maculatus	70.83	0.00e+00	808.00
IUUC-Zma-135699	Zea mays	36.92	4.00e-148	518.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence