iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Mac-065137

Ensembl Protein ID

GSMUA_Achr8P33050_001

UniProt Accession

M0TVQ7; M0TVQ7_MUSAM

Protein Name

Protein HIRA

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
GSMUA_Achr8G33050_001	GSMUA_Achr8T33050_001	GSMUA_Achr8P33050_001

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/DCX/DWD	2.30e-23	82.1	123	160
UBD/Beta-Prp	8.30e-41	140.9	13	208

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgvll 36
           gHt++v +l++ +d  +l+sGs D+ti++W+++tg ++
   Q: 123  GHTADVVDLNWsPDdLTLASGSLDNTIHIWNITTGICT 160
           8***********776889*****************997 PP

UBD/Beta-Prp

   S: 10   ksvitcvkfspdksllatgsrdgtikvwdvttgkl...........lrslsgheaevtavkfspdgkilvtgseDrtikvw....... 79
             +i ++++  ++  +atg+ d+++++w++++  +           l++l +h + v++v++ ++g +l++gs+D++i +        
   Q: 13   GMQIFSIDIQAGGLRFATGGGDHKVRIWNMKSVATdsendssnprlLATLRDHFGSVNCVRWAKHGRFLASGSDDHVILIHerkpgsg 100
           556667778788999*****************888**********************************************8888888 PP
   S: 80   ..........dlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdgnllvsGsl 157
                     d+++ k ++tl+gh+++v++l++sp++ +l+sGs d+ti++w++ tg c   +l+gh+++v +v+++p g+ ++s s+
   Q: 101  ttefgsgeppDVENWKVTMTLRGHTADVVDLNWSPDDLTLASGSLDNTIHIWNITTGICTA-VLRGHSSLVKGVTWDPIGSFIASQSD 187
           8888888888888************************************************.************************** PP
   S: 158  DrtvrlWdlktgkllrtltggh 179
           D+tv +W+ +  +l ++ +g h
   Q: 188  DKTVIIWRTSDWSLAHRTEG-H 208
           ********999999998887.5 PP

Organism

Musa acuminata

Functional Description
(View)

Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle.

Protein Sequence
(Fasta)

MITEKPSWVT HEGMQIFSID IQAGGLRFAT GGGDHKVRIW NMKSVATDSE NDSSNPRLLA 60
TLRDHFGSVN CVRWAKHGRF LASGSDDHVI LIHERKPGSG TTEFGSGEPP DVENWKVTMT 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGATCACCG AGAAGCCTAG CTGGGTTACG CATGAGGGGA TGCAGATCTT CTCCATCGAC 60
ATCCAAGCCG GAGGTCTCCG GTTTGCCACT GGTGGCGGAG ACCACAAGGT GAGTCTTTTT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0156--Chromatin regulator
KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0678--Repressor
KW-0804--Transcription
KW-0805--Transcription regulation
KW-0853--WD repeat

Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR031120--HIR1
IPR011494--Hira
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF07569--Hira
PF00400--WD40

PRINTS

PR00320--GPROTEINBRPT

SMART

SM00320--WD40

Gene Ontology

GO:0005634--C:nucleus
GO:0016569--P:covalent chromatin modification
GO:0006355--P:regulation of transcription, DNA-templated
GO:0006351--P:transcription, DNA-templated

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Aml-001723	Ailuropoda melanoleuca	38.43	4.00e-83	302.00
IUUC-Apl-003197	Anas platyrhynchos	37.61	3.00e-83	302.00
IUUC-Aca-004733	Anolis carolinensis	37.87	7.00e-88	318.00
IUUC-Ago-007766	Ashbya gossypii	31.92	4.00e-57	216.00
IUUC-Acl-008104	Aspergillus clavatus	34.22	8.00e-68	251.00
IUUC-Afl-008591	Aspergillus flavus	33.74	1.00e-66	248.00
IUUC-Afu-008781	Aspergillus fumigatus	32.66	1.00e-63	238.00
IUUC-Ani-009272	Aspergillus nidulans	29.68	3.00e-53	203.00
IUUC-Ang-009655	Aspergillus niger	34.46	6.00e-69	255.00
IUUC-Aor-010119	Aspergillus oryzae	33.74	1.00e-66	248.00
IUUC-Ate-010530	Aspergillus terreus	26.80	1.00e-53	204.00
IUUC-Bgr-012237	Blumeria graminis	34.39	3.00e-64	239.00
IUUC-Bta-013320	Bos taurus	38.23	8.00e-83	301.00
IUUC-Bci-013795	Botrytis cinerea	34.70	2.00e-71	263.00
IUUC-Bra-016651	Brassica rapa	66.88	0.00e+00	1207.00
IUUC-Cel-018692	Caenorhabditis elegans	29.03	1.00e-43	171.00
IUUC-Cja-018987	Callithrix jacchus	38.19	1.00e-77	284.00
IUUC-Cfa-020132	Canis familiaris	38.43	4.00e-83	302.00
IUUC-Cpo-021484	Cavia porcellus	38.84	2.00e-87	317.00
IUUC-Cre-022846	Chlamydomonas reinhardtii	35.98	3.00e-72	266.00
IUUC-Csa-023081	Chlorocebus sabaeus	39.27	1.00e-89	324.00
IUUC-Cin-025182	Ciona intestinalis	36.03	2.00e-88	320.00
IUUC-Csv-026154	Ciona savignyi	38.20	9.00e-84	304.00
IUUC-Cgl-026655	Colletotrichum gloeosporioides	34.98	3.00e-65	243.00
IUUC-Cne-026891	Cryptococcus neoformans	39.39	2.00e-82	299.00
IUUC-Cme-027349	Cyanidioschyzon merolae	28.89	5.00e-51	196.00
IUUC-Dre-027655	Danio rerio	35.53	2.00e-88	320.00
IUUC-Dor-030687	Dipodomys ordii	32.54	8.00e-67	248.00
IUUC-Dse-031334	Dothistroma septosporum	34.63	2.00e-68	253.00
IUUC-Dme-031746	Drosophila melanogaster	38.49	1.00e-88	320.00
IUUC-Ete-032384	Echinops telfairi	35.45	2.00e-65	244.00
IUUC-Eca-033430	Equus caballus	38.43	2.00e-84	306.00
IUUC-Fca-036121	Felis catus	38.36	2.00e-84	307.00
IUUC-Fal-036817	Ficedula albicollis	37.39	5.00e-84	305.00
IUUC-Fox-037906	Fusarium oxysporum	34.89	2.00e-67	249.00
IUUC-Gmo-039151	Gadus morhua	42.94	1.00e-83	304.00
IUUC-Ggr-040016	Gaeumannomyces graminis	34.46	3.00e-67	249.00
IUUC-Gga-040936	Gallus gallus	39.11	2.00e-87	317.00
IUUC-Gac-041405	Gasterosteus aculeatus	37.37	1.00e-83	304.00
IUUC-Ggo-045430	Gorilla gorilla	39.27	1.00e-89	324.00
IUUC-Hsa-046442	Homo sapiens	39.27	1.00e-89	324.00
IUUC-Itr-048910	Ictidomys tridecemlineatus	43.00	6.00e-64	236.00
IUUC-Kpa-049145	Komagataella pastoris	33.41	9.00e-60	224.00
IUUC-Lch-050474	Latimeria chalumnae	38.05	5.00e-83	302.00
IUUC-Loc-052119	Lepisosteus oculatus	37.53	9.00e-83	301.00
IUUC-Lma-053237	Leptosphaeria maculans	32.92	5.00e-64	239.00
IUUC-Laf-053718	Loxodonta africana	39.83	8.00e-90	324.00
IUUC-Mcc-055621	Macaca mulatta	37.38	2.00e-76	280.00
IUUC-Meu-055914	Macropus eugenii	37.99	5.00e-56	212.00
IUUC-Mor-057090	Magnaporthe oryzae	35.37	4.00e-68	253.00
IUUC-Mpo-057364	Magnaporthe poae	34.46	1.00e-67	251.00
IUUC-Mla-058914	Melampsora laricipopulina	27.42	4.00e-81	295.00
IUUC-Mga-060181	Meleagris gallopavo	38.74	5.00e-83	302.00
IUUC-Mvi-060432	Microbotryum violaceum	34.04	3.00e-57	216.00
IUUC-Mmr-060871	Microcebus murinus	39.27	4.00e-89	322.00
IUUC-Mdo-062301	Monodelphis domestica	38.92	2.00e-87	317.00
IUUC-Mmu-063888	Mus musculus	39.27	1.00e-89	324.00
IUUC-Mpu-066732	Mustela putorius furo	38.43	3.00e-83	303.00
IUUC-Mlu-067542	Myotis lucifugus	38.28	3.00e-85	309.00
IUUC-Nfi-068396	Neosartorya fischeri	32.66	1.00e-63	238.00
IUUC-Ncr-068842	Neurospora crassa	36.01	3.00e-69	256.00
IUUC-Nle-070156	Nomascus leucogenys	39.27	1.00e-89	324.00
IUUC-Ont-072105	Oreochromis niloticus	38.58	2.00e-84	306.00
IUUC-Ocu-074962	Oryctolagus cuniculus	38.65	1.00e-84	307.00
IUUC-Olo-081048	Oryza longistaminata	71.55	0.00e+00	1162.00
IUUC-Ola-087302	Oryzias latipes	36.32	1.00e-78	288.00
IUUC-Olu-087611	Ostreococcus lucimarinus	36.57	3.00e-158	551.00
IUUC-Oga-087935	Otolemur garnettii	38.34	5.00e-85	308.00
IUUC-Oar-089229	Ovis aries	33.55	3.00e-64	239.00
IUUC-Ptr-090715	Pan troglodytes	39.27	1.00e-89	324.00
IUUC-Pan-092318	Papio anubis	38.86	2.00e-85	310.00
IUUC-Psi-094053	Pelodiscus sinensis	36.38	2.00e-80	293.00
IUUC-Pno-094985	Phaeosphaeria nodorum	31.33	7.00e-58	218.00
IUUC-Ppa-095499	Physcomitrella patens	49.01	0.00e+00	892.00
IUUC-Pfo-096857	Poecilia formosa	36.25	7.00e-81	295.00
IUUC-Pab-098047	Pongo abelii	39.27	1.00e-89	324.00
IUUC-Pca-100558	Procavia capensis	49.22	2.00e-48	187.00
IUUC-Ppe-101261	Prunus persica	72.03	0.00e+00	1360.00
IUUC-Pva-102683	Pteropus vampyrus	39.06	1.00e-86	313.00
IUUC-Pgr-103660	Puccinia graminis	28.26	3.00e-69	256.00
IUUC-Ptt-103900	Puccinia triticina	28.34	3.00e-62	232.00
IUUC-Pte-104209	Pyrenophora teres	32.84	2.00e-66	247.00
IUUC-Pyt-104802	Pyrenophora triticirepentis	32.84	6.00e-66	245.00
IUUC-Rno-105566	Rattus norvegicus	39.27	2.00e-89	323.00
IUUC-Sce-106291	Saccharomyces cerevisiae	32.29	4.00e-60	225.00
IUUC-Sha-107514	Sarcophilus harrisii	36.05	3.00e-72	266.00
IUUC-Spo-108162	Schizosaccharomyces pombe	39.14	7.00e-74	271.00
IUUC-Smo-109186	Selaginella moellendorffii	51.93	0.00e+00	895.00
IUUC-Stu-112705	Solanum tuberosum	69.75	0.00e+00	1335.00
IUUC-Sar-113222	Sorex araneus	37.17	4.00e-78	285.00
IUUC-Sre-115061	Sporisorium reilianum	34.07	5.00e-71	262.00
IUUC-Ssc-116364	Sus scrofa	38.21	2.00e-84	306.00
IUUC-Tgu-116645	Taeniopygia guttata	36.96	8.00e-84	305.00
IUUC-Tru-117590	Takifugu rubripes	38.46	4.00e-88	318.00
IUUC-Tsy-119212	Tarsius syrichta	35.82	4.00e-71	262.00
IUUC-Tni-119915	Tetraodon nigroviridis	38.15	5.00e-88	318.00
IUUC-Tre-121887	Trichoderma reesei	35.05	1.00e-62	234.00
IUUC-Tvi-122262	Trichoderma virens	34.31	2.00e-61	230.00
IUUC-Tme-127202	Tuber melanosporum	30.15	4.00e-48	186.00
IUUC-Tbe-127350	Tupaia belangeri	34.44	2.00e-50	194.00
IUUC-Ttr-129077	Tursiops truncatus	35.60	4.00e-75	275.00
IUUC-Uma-129465	Ustilago maydis	33.85	1.00e-73	271.00
IUUC-Vda-129844	Verticillium dahliae	33.49	1.00e-65	244.00
IUUC-Xtr-132057	Xenopus tropicalis	37.61	7.00e-87	315.00
IUUC-Xma-134139	Xiphophorus maculatus	30.46	7.00e-69	254.00
IUUC-Yli-134424	Yarrowia lipolytica	33.41	3.00e-60	226.00

Created Date

25-Jun-2017

Functional Description

Protein Fasta Sequence

Nucleotide Fasta Sequence