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Basic Information Integrated Annotations
Tag Content
iUUCD ID IUUC-Sce-106140
Ensembl Protein ID YBL106C
UniProt Accession P38163; D6VPP7; SRO77_YEAST
Genbank Protein ID CAA55989.1; CAA84933.1; DAA07017.2
Protein Name Lethal(2) giant larvae protein homolog SRO77; Sodium protection protein 2; Suppressor of RHO3 protein 77
Genbank Nucleotide ID X79489; Z35867; BK006936
Gene Name SRO77; SNI2; SOP2; YBL106C; YBL0806
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YBL106C YBL106C YBL106C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Post-translational Modifications (PTMs)
dbPAFdbPTMBioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 8.50e-06 24.5 247 273
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 12   sd.tllvsGsdDgtikvWDlrtgvllk 37
           ++  ++++   D+++  WD+ +g+l++
   Q: 247  PNsLHILTVHEDNSLVFWDVNSGKLIH 273
           45579*****************99876 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Acts as an allosteric regulator of polarized exocytosis by promoting the targeted fusion of vesicles with the plasma membrane. Involved in maintenance of ion homeostasis in cells exposed to NaCl stress. May be involved in the targeting of the myosin proteins to their intrinsic pathways. Multicopy suppressor of RHO3. May also participate in the maintenance of cell polarity and bud growth.
 Acts as an allosteric regulator of polarized exocytosis by promoting the targeted fusion of vesicles with the plasma membrane. Involved in maintenance of ion homeostasis in cells exposed to NaCl stress. May be involved in the targeting of the myosin proteins to their intrinsic pathways. Multicopy suppressor of RHO3. May also participate in the maintenance of cell polarity and bud growth.
Protein Sequence
(Fasta)
MFKKSRHLKN VSNAIKSARV HDVSNGINSK FFDTKKICTY GINGRITVTT FDYTQSLLAV 60
ATTAGEIHVY GQKQIEVVFT LKNRPQIKHM RFIKGIYLIA VDEKSNIIVL SVHSKQILTT 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106140|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGTTTAAGA AAAGCAGGCA TTTGAAGAAT GTGTCAAATG CTATCAAATC CGCGAGAGTT 60
CATGACGTCT CAAATGGTAT TAACTCCAAA TTTTTCGATA CTAAGAAAAT ATGCACATAC 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106140|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0268--Exocytosis
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR013905--Lgl_C_dom
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08596--Lgl_C
SMART

SM00320--WD40
Gene Ontology

GO:0005737--C:cytoplasm
GO:0005886--C:plasma membrane
GO:0005096--F:GTPase activator activity
GO:0017137--F:Rab GTPase binding
GO:0019905--F:syntaxin binding
GO:0030010--P:establishment of cell polarity
GO:0006887--P:exocytosis
GO:0006893--P:Golgi to plasma membrane transport
GO:0017157--P:regulation of exocytosis
GO:0050708--P:regulation of protein secretion
KEGG sce:YBL106C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000919 Aegilops tauschii 28.00 9.00e-12 63.90
IUUC-Aml-001923 Ailuropoda melanoleuca 23.83 3.00e-12 65.50
IUUC-Atr-002583 Amborella trichopoda 22.79 6.00e-09 54.70
IUUC-Apl-003619 Anas platyrhynchos 20.15 6.00e-08 51.20
IUUC-Aca-004796 Anolis carolinensis 22.66 8.00e-11 61.20
IUUC-Aly-005770 Arabidopsis lyrata 23.03 8.00e-07 47.80
IUUC-Ath-007643 Arabidopsis thaliana 23.13 6.00e-08 51.20
IUUC-Ago-007756 Ashbya gossypii 46.03 0.00e+00 894.00
IUUC-Acl-008044 Aspergillus clavatus 30.45 6.00e-132 462.00
IUUC-Afl-008612 Aspergillus flavus 31.28 2.00e-128 451.00
IUUC-Afu-008901 Aspergillus fumigatus 30.72 5.00e-136 476.00
IUUC-Ani-009223 Aspergillus nidulans 32.40 4.00e-120 424.00
IUUC-Ang-009861 Aspergillus niger 31.49 6.00e-128 449.00
IUUC-Aor-010078 Aspergillus oryzae 31.32 7.00e-130 456.00
IUUC-Ate-010462 Aspergillus terreus 31.21 3.00e-128 451.00
IUUC-Ame-010663 Astyanax mexicanus 22.89 1.00e-10 60.50
IUUC-Bgr-012214 Blumeria graminis 26.87 8.00e-86 310.00
IUUC-Bta-013413 Bos taurus 23.83 4.00e-12 65.50
IUUC-Bci-013698 Botrytis cinerea 31.85 7.00e-130 456.00
IUUC-Bdi-015011 Brachypodium distachyon 28.57 5.00e-11 61.60
IUUC-Bol-015788 Brassica oleracea 27.62 9.00e-09 54.30
IUUC-Bra-017845 Brassica rapa 23.98 1.00e-08 53.90
IUUC-Cel-018519 Caenorhabditis elegans 20.75 3.00e-05 42.70
IUUC-Cja-018984 Callithrix jacchus 23.44 5.00e-12 65.10
IUUC-Cfa-021212 Canis familiaris 23.83 3.00e-12 65.50
IUUC-Cpo-021354 Cavia porcellus 21.38 4.00e-04 38.90
IUUC-Csa-023249 Chlorocebus sabaeus 23.83 4.00e-12 65.10
IUUC-Cho-024743 Choloepus hoffmanni 25.58 5.00e-05 41.60
IUUC-Cin-025731 Ciona intestinalis 25.89 6.00e-08 48.90
IUUC-Csv-026036 Ciona savignyi 21.82 9.00e-09 54.30
IUUC-Cgl-026432 Colletotrichum gloeosporioides 30.73 4.00e-108 384.00
IUUC-Dre-027886 Danio rerio 22.09 8.00e-10 57.80
IUUC-Dno-029866 Dasypus novemcinctus 24.10 1.00e-10 60.50
IUUC-Dor-031024 Dipodomys ordii 24.26 2.00e-10 59.30
IUUC-Dse-031263 Dothistroma septosporum 30.88 3.00e-128 451.00
IUUC-Dme-031607 Drosophila melanogaster 23.83 1.00e-06 47.40
IUUC-Ete-032893 Echinops telfairi 23.83 4.00e-12 65.50
IUUC-Eca-034305 Equus caballus 30.21 2.00e-04 39.70
IUUC-Eeu-034943 Erinaceus europaeus 23.41 4.00e-09 55.50
IUUC-Fca-036249 Felis catus 23.83 4.00e-12 65.50
IUUC-Fal-036915 Ficedula albicollis 21.88 6.00e-11 61.60
IUUC-Fox-037853 Fusarium oxysporum 30.45 2.00e-122 431.00
IUUC-Fso-038327 Fusarium solani 30.37 2.00e-119 421.00
IUUC-Gmo-038889 Gadus morhua 25.00 1.00e-11 63.50
IUUC-Ggr-039723 Gaeumannomyces graminis 30.81 2.00e-121 428.00
IUUC-Gga-040529 Gallus gallus 23.72 8.00e-11 61.20
IUUC-Gac-041391 Gasterosteus aculeatus 23.65 2.00e-09 56.60
IUUC-Gma-043398 Glycine max 28.57 2.00e-09 56.60
IUUC-Ggo-045391 Gorilla gorilla 23.83 5.00e-12 65.10
IUUC-Hsa-045903 Homo sapiens 23.83 5.00e-12 65.10
IUUC-Hvu-047650 Hordeum vulgare 30.11 4.00e-13 68.20
IUUC-Itr-048031 Ictidomys tridecemlineatus 19.62 1.00e-04 40.40
IUUC-Lch-050258 Latimeria chalumnae 22.22 5.00e-04 38.50
IUUC-Lpe-051115 Leersia perrieri 29.94 6.00e-11 61.20
IUUC-Loc-052677 Lepisosteus oculatus 23.05 3.00e-09 55.80
IUUC-Lma-053029 Leptosphaeria maculans 31.90 8.00e-137 479.00
IUUC-Laf-053723 Loxodonta africana 23.83 7.00e-12 63.90
IUUC-Mcc-055526 Macaca mulatta 23.83 5.00e-12 65.10
IUUC-Meu-056246 Macropus eugenii 23.40 4.00e-07 48.90
IUUC-Mor-057129 Magnaporthe oryzae 31.09 9.00e-121 426.00
IUUC-Mpo-057585 Magnaporthe poae 30.27 1.00e-118 419.00
IUUC-Mtr-058362 Medicago truncatula 28.93 9.00e-10 57.40
IUUC-Mla-058927 Melampsora laricipopulina 27.97 3.00e-15 75.90
IUUC-Mga-060026 Meleagris gallopavo 21.04 3.00e-08 52.40
IUUC-Mvi-060348 Microbotryum violaceum 25.34 4.00e-23 102.00
IUUC-Mmr-061246 Microcebus murinus 23.83 5.00e-12 65.10
IUUC-Mdo-062626 Monodelphis domestica 24.12 4.00e-11 62.40
IUUC-Mmu-063848 Mus musculus 23.44 7.00e-12 64.70
IUUC-Mac-065436 Musa acuminata 26.40 2.00e-06 46.60
IUUC-Mpu-065780 Mustela putorius furo 23.32 6.00e-11 60.10
IUUC-Mlu-067504 Myotis lucifugus 24.32 9.00e-11 60.80
IUUC-Nfi-068318 Neosartorya fischeri 30.96 4.00e-135 473.00
IUUC-Ncr-068624 Neurospora crassa 29.81 8.00e-117 412.00
IUUC-Nle-069640 Nomascus leucogenys 23.83 5.00e-12 65.10
IUUC-Opr-070681 Ochotona princeps 28.41 4.00e-06 45.40
IUUC-Ont-071645 Oreochromis niloticus 24.37 3.00e-12 65.90
IUUC-Oan-073349 Ornithorhynchus anatinus 24.26 6.00e-10 55.80
IUUC-Ocu-074803 Oryctolagus cuniculus 23.83 4.00e-12 65.90
IUUC-Oba-075180 Oryza barthii 28.57 3.00e-11 62.40
IUUC-Obr-076139 Oryza brachyantha 29.14 2.00e-10 60.10
IUUC-Ogl-077142 Oryza glaberrima 28.57 4.00e-11 62.00
IUUC-Ogu-079037 Oryza glumaepatula 27.43 4.00e-10 58.90
IUUC-Oin-079192 Oryza indica 28.57 3.00e-11 62.40
IUUC-Olo-080693 Oryza longistaminata 28.57 2.00e-11 63.20
IUUC-Oni-082885 Oryza nivara 28.57 3.00e-11 62.40
IUUC-Oru-084893 Oryza rufipogon 28.57 2.00e-11 62.80
IUUC-Osa-085916 Oryza sativa 28.57 3.00e-11 62.40
IUUC-Ola-087197 Oryzias latipes 26.83 8.00e-05 41.20
IUUC-Oga-088333 Otolemur garnettii 23.74 3.00e-12 65.90
IUUC-Oar-090261 Ovis aries 24.02 2.00e-10 59.70
IUUC-Ptr-091012 Pan troglodytes 23.83 5.00e-12 65.10
IUUC-Pan-091748 Papio anubis 24.12 5.00e-11 62.00
IUUC-Psi-093405 Pelodiscus sinensis 22.96 4.00e-11 62.00
IUUC-Pno-095147 Phaeosphaeria nodorum 31.68 4.00e-129 453.00
IUUC-Pfo-096143 Poecilia formosa 22.39 3.00e-10 59.30
IUUC-Pab-098201 Pongo abelii 23.83 5.00e-12 65.10
IUUC-Pop-099276 Populus trichocarpa 27.86 4.00e-09 55.10
IUUC-Pca-101111 Procavia capensis 23.32 3.00e-10 59.30
IUUC-Ppe-101236 Prunus persica 25.86 1.00e-10 60.50
IUUC-Pva-102373 Pteropus vampyrus 21.45 2.00e-05 42.70
IUUC-Pgr-103363 Puccinia graminis 24.70 3.00e-05 42.70
IUUC-Pte-104412 Pyrenophora teres 31.90 1.00e-133 468.00
IUUC-Pyt-104770 Pyrenophora triticirepentis 32.62 1.00e-141 495.00
IUUC-Rno-106102 Rattus norvegicus 23.44 6.00e-12 64.70
IUUC-Sit-110386 Setaria italica 25.63 5.00e-09 55.10
IUUC-Sly-111338 Solanum lycopersicum 26.72 1.00e-06 45.40
IUUC-Stu-112417 Solanum tuberosum 26.72 2.00e-06 44.70
IUUC-Sar-113007 Sorex araneus 24.11 6.00e-11 61.60
IUUC-Sbi-114175 Sorghum bicolor 27.65 3.00e-09 55.80
IUUC-Sre-115050 Sporisorium reilianum 26.84 2.00e-23 102.00
IUUC-Ssc-115307 Sus scrofa 24.22 2.00e-12 65.90
IUUC-Tgu-116507 Taeniopygia guttata 23.05 3.00e-10 59.30
IUUC-Tru-118038 Takifugu rubripes 25.00 3.00e-10 59.30
IUUC-Tsy-119133 Tarsius syrichta 26.00 5.00e-11 61.60
IUUC-Tni-120014 Tetraodon nigroviridis 25.00 4.00e-10 58.50
IUUC-Tca-121778 Theobroma cacao 26.67 6.00e-10 58.20
IUUC-Tre-122192 Trichoderma reesei 29.77 1.00e-118 418.00
IUUC-Tvi-122424 Trichoderma virens 30.33 2.00e-120 425.00
IUUC-Tae-125452 Triticum aestivum 28.57 5.00e-12 65.10
IUUC-Tur-126560 Triticum urartu 29.30 3.00e-10 58.90
IUUC-Tbe-127510 Tupaia belangeri 21.57 1.00e-09 57.40
IUUC-Ttr-128804 Tursiops truncatus 23.05 6.00e-12 64.70
IUUC-Uma-129388 Ustilago maydis 25.37 6.00e-22 98.20
IUUC-Vda-129843 Verticillium dahliae 29.87 1.00e-111 395.00
IUUC-Vpa-130524 Vicugna pacos 23.72 1.00e-10 60.10
IUUC-Vvi-131379 Vitis vinifera 27.32 2.00e-09 56.20
IUUC-Xtr-132160 Xenopus tropicalis 30.49 3.00e-06 45.80
IUUC-Xma-133008 Xiphophorus maculatus 22.01 7.00e-10 57.80
IUUC-Yli-134491 Yarrowia lipolytica 33.33 3.00e-163 566.00
IUUC-Zma-135923 Zea mays 27.59 4.00e-08 52.40
Created Date 25-Jun-2017

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