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Tag Content
UUCD2 ID IUUC-Mlu-068123
UUCD1 version UUC-MyL-00585
Ensembl Protein ID ENSMLUP00000011387.2
UniProt Accession G1PKP7; G1PKP7_MYOLU
Genbank Protein ID ENSMLUP00000011387
Protein Name Uncharacterized protein
Genbank Nucleotide ID AAPE02043925
Gene Name NLE1
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
ENSMLUG00000012506.2 ENSMLUT00000012512.2 ENSMLUP00000011387.2
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 1.60e-66 217.2 197 240
UBD/Beta-Prp 7.10e-80 268.4 106 299
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf......sd.tllvsGsdDgtikvWDlrtgvllk 37
           gH+ ++t+l++      ++ ++++s+s Dg+++vWD+++g++++
   Q: 197  GHSKWITGLSWeplhvnPEcRYVASSSKDGSVRVWDTTSGRCER 240
           8***************9889**********************86 PP
   

   UBD/Beta-Prp
   S: 44   llrslsgheaevtavkfspdgkilvtgseDrtikvwdlstgkcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleet 132
           + +sl+gh+++v +v fsp+gk+l++gs D t++ wdlst ++  t +gh + vls+s+sp+g+kl+sG +   i +wd +tg+ +  t
   Q: 106  CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCQGHRHWVLSISWSPDGKKLASGCKNGQILLWDPNTGKQVGRT 194
           5899************************************************************************************* PP
   S: 133  lsghdgvvncvvv.....hpdgnllvsGslDrtvrlWdlktgkllrtltgghtdsvyslsfdsngkelvsgsldgtvklwdlqtgecvr 216
           l+gh+++++++++     +p++++++s+s+D+ vr+Wd  +g++ r ltg ht+sv++l +  +g  l s+s+d+t+k+w  + g   r
   Q: 195  LAGHSKWITGLSWeplhvNPECRYVASSSKDGSVRVWDTTSGRCERILTG-HTQSVTCLRWGGDG-LLYSASQDRTIKVWRAHDGVLCR 281
           *********98652222278899**************************9.************98.*********************** PP
   S: 217  tlnghtdnvksvrfspnde 235
           tl+gh  +v+ +++s  d 
   Q: 282  TLQGHGHWVNTMALS-TDY 299
           **************9.333 PP
   
Organism Myotis lucifugus
Protein Sequence
(Fasta)
MAAAVADEAA ARDVQRLLVQ FQDEGGQLLG SPFDVPVDIT PDKLQLICNA LLAQEDPLPL 60
AFYVHDAEIV SSLGRTLEAQ AVETEKVLDI IYQPQAIFKV RAVTRCTSSL EGHSEAVISV 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Mlu-068123|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGCGGCGG CAGTGGCGGT GGGTGTGCGT GGATGGGGGC GGGGGCGCGC GACGGGCGCA 60
GGTGCCCGGG GTCCGCGAGG CGGGAGGGCG GCGGGAGGGG GGACCCTCCT CTCCCCGGCG 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Mlu-068123|E3,WD_repeat;UBD,Beta-Prp|Myotis lucifugus
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0181--Complete proteome
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR001632--Gprotein_B
IPR012972--NLE
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF08154--NLE
PF00400--WD40
PRINTS

PR00319--GPROTEINB
PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0005730--C:nucleolus
GO:0061484--P:hematopoietic stem cell homeostasis
GO:0001826--P:inner cell mass cell differentiation
GO:0001822--P:kidney development
GO:2001268--P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway
GO:0045930--P:negative regulation of mitotic cell cycle
GO:0007219--P:Notch signaling pathway
GO:0090263--P:positive regulation of canonical Wnt signaling pathway
GO:0042273--P:ribosomal large subunit biogenesis
GO:0048705--P:skeletal system morphogenesis
GO:0001756--P:somitogenesis
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000437 Aegilops tauschii 58.37 1.00e-169 589.00
IUUC-Aml-001793 Ailuropoda melanoleuca 96.41 0.00e+00 945.00
IUUC-Atr-002507 Amborella trichopoda 59.06 2.00e-168 585.00
IUUC-Apl-003964 Anas platyrhynchos 83.92 0.00e+00 813.00
IUUC-Aly-006396 Arabidopsis lyrata 54.47 2.00e-161 561.00
IUUC-Ath-007278 Arabidopsis thaliana 54.68 3.00e-161 561.00
IUUC-Ago-007951 Ashbya gossypii 48.36 7.00e-130 457.00
IUUC-Acl-008298 Aspergillus clavatus 46.67 2.00e-119 422.00
IUUC-Afl-008581 Aspergillus flavus 52.38 2.00e-108 385.00
IUUC-Afu-008906 Aspergillus fumigatus 45.66 1.00e-118 420.00
IUUC-Ani-009189 Aspergillus nidulans 44.72 3.00e-116 412.00
IUUC-Ang-009630 Aspergillus niger 47.59 2.00e-122 432.00
IUUC-Aor-010038 Aspergillus oryzae 47.29 5.00e-126 444.00
IUUC-Ate-010278 Aspergillus terreus 46.29 1.00e-121 429.00
IUUC-Ame-011890 Astyanax mexicanus 80.34 0.00e+00 820.00
IUUC-Bgr-012011 Blumeria graminis 48.03 8.00e-131 460.00
IUUC-Bta-012964 Bos taurus 96.41 0.00e+00 945.00
IUUC-Bci-013592 Botrytis cinerea 45.62 6.00e-121 427.00
IUUC-Bdi-015035 Brachypodium distachyon 58.46 1.00e-170 592.00
IUUC-Bol-015501 Brassica oleracea 55.56 1.00e-161 562.00
IUUC-Bra-017642 Brassica rapa 55.34 1.00e-160 559.00
IUUC-Cel-018430 Caenorhabditis elegans 57.94 1.00e-167 582.00
IUUC-Cja-019125 Callithrix jacchus 95.99 0.00e+00 945.00
IUUC-Cfa-021013 Canis familiaris 95.38 0.00e+00 857.00
IUUC-Cpo-021743 Cavia porcellus 95.56 0.00e+00 939.00
IUUC-Cre-022973 Chlamydomonas reinhardtii 46.50 7.00e-121 427.00
IUUC-Csa-024270 Chlorocebus sabaeus 95.99 0.00e+00 946.00
IUUC-Cin-025795 Ciona intestinalis 66.10 0.00e+00 685.00
IUUC-Csv-025953 Ciona savignyi 66.95 0.00e+00 683.00
IUUC-Cgl-026517 Colletotrichum gloeosporioides 51.46 1.00e-108 386.00
IUUC-Cne-026901 Cryptococcus neoformans 48.91 4.00e-138 484.00
IUUC-Cme-027281 Cyanidioschyzon merolae 47.67 2.00e-113 402.00
IUUC-Dre-028515 Danio rerio 78.01 0.00e+00 803.00
IUUC-Dno-029596 Dasypus novemcinctus 95.77 0.00e+00 940.00
IUUC-Dor-030494 Dipodomys ordii 95.76 0.00e+00 936.00
IUUC-Dse-031538 Dothistroma septosporum 48.65 4.00e-130 458.00
IUUC-Dme-031974 Drosophila melanogaster 59.83 4.00e-168 584.00
IUUC-Ete-032948 Echinops telfairi 97.13 5.00e-118 417.00
IUUC-Eca-033399 Equus caballus 97.88 0.00e+00 950.00
IUUC-Eeu-035013 Erinaceus europaeus 95.22 1.00e-116 412.00
IUUC-Fca-035860 Felis catus 96.20 0.00e+00 943.00
IUUC-Fal-037069 Ficedula albicollis 88.00 1.00e-132 465.00
IUUC-Fox-038059 Fusarium oxysporum 46.56 2.00e-125 442.00
IUUC-Fso-038445 Fusarium solani 47.81 3.00e-126 445.00
IUUC-Gmo-039319 Gadus morhua 76.17 0.00e+00 736.00
IUUC-Ggr-040095 Gaeumannomyces graminis 47.59 1.00e-122 433.00
IUUC-Gga-040303 Gallus gallus 86.00 6.00e-131 459.00
IUUC-Gac-042267 Gasterosteus aculeatus 78.48 0.00e+00 764.00
IUUC-Gma-043974 Glycine max 57.66 5.00e-170 590.00
IUUC-Ggo-044637 Gorilla gorilla 96.60 0.00e+00 942.00
IUUC-Hsa-046128 Homo sapiens 96.62 0.00e+00 952.00
IUUC-Hvu-047373 Hordeum vulgare 57.82 1.00e-168 586.00
IUUC-Itr-048070 Ictidomys tridecemlineatus 95.40 0.00e+00 941.00
IUUC-Kpa-049274 Komagataella pastoris 44.47 9.00e-126 443.00
IUUC-Lch-049907 Latimeria chalumnae 81.97 0.00e+00 824.00
IUUC-Lpe-050778 Leersia perrieri 53.65 4.00e-152 531.00
IUUC-Loc-051889 Lepisosteus oculatus 80.97 0.00e+00 830.00
IUUC-Lma-053041 Leptosphaeria maculans 49.18 5.00e-116 411.00
IUUC-Laf-053598 Loxodonta africana 96.41 0.00e+00 949.00
IUUC-Mcc-055660 Macaca mulatta 95.78 0.00e+00 943.00
IUUC-Meu-056197 Macropus eugenii 80.38 0.00e+00 782.00
IUUC-Mor-056949 Magnaporthe oryzae 46.47 1.00e-120 426.00
IUUC-Mpo-057571 Magnaporthe poae 44.75 5.00e-63 234.00
IUUC-Mtr-058530 Medicago truncatula 58.09 1.00e-165 576.00
IUUC-Mla-059133 Melampsora laricipopulina 46.48 4.00e-125 441.00
IUUC-Mga-059252 Meleagris gallopavo 84.38 0.00e+00 662.00
IUUC-Mvi-060522 Microbotryum violaceum 49.39 3.00e-135 475.00
IUUC-Mmr-061117 Microcebus murinus 96.00 0.00e+00 936.00
IUUC-Mdo-062892 Monodelphis domestica 89.43 0.00e+00 892.00
IUUC-Mmu-064108 Mus musculus 95.35 0.00e+00 914.00
IUUC-Mac-064430 Musa acuminata 59.53 5.00e-173 600.00
IUUC-Mpu-065882 Mustela putorius furo 96.19 0.00e+00 938.00
IUUC-Nfi-068484 Neosartorya fischeri 46.14 3.00e-118 418.00
IUUC-Ncr-068649 Neurospora crassa 43.54 5.00e-115 407.00
IUUC-Nle-069140 Nomascus leucogenys 96.39 0.00e+00 942.00
IUUC-Opr-070220 Ochotona princeps 88.32 0.00e+00 821.00
IUUC-Ont-072643 Oreochromis niloticus 80.21 0.00e+00 820.00
IUUC-Ocu-074007 Oryctolagus cuniculus 95.98 0.00e+00 913.00
IUUC-Oba-075904 Oryza barthii 58.89 6.00e-172 597.00
IUUC-Obr-076280 Oryza brachyantha 58.46 5.00e-171 593.00
IUUC-Ogl-077425 Oryza glaberrima 58.89 5.00e-172 597.00
IUUC-Ogu-078586 Oryza glumaepatula 58.89 6.00e-172 597.00
IUUC-Oin-079489 Oryza indica 56.75 5.00e-163 567.00
IUUC-Olo-080766 Oryza longistaminata 58.76 1.00e-171 596.00
IUUC-Ome-081905 Oryza meridionalis 58.89 6.00e-172 597.00
IUUC-Oni-083022 Oryza nivara 58.89 3.00e-172 597.00
IUUC-Opu-083615 Oryza punctata 58.89 4.00e-172 597.00
IUUC-Oru-085076 Oryza rufipogon 58.89 3.00e-172 597.00
IUUC-Osa-085744 Oryza sativa 59.10 1.00e-172 598.00
IUUC-Ola-087290 Oryzias latipes 78.53 0.00e+00 806.00
IUUC-Olu-087898 Ostreococcus lucimarinus 52.62 5.00e-144 504.00
IUUC-Oga-088980 Otolemur garnettii 95.12 0.00e+00 932.00
IUUC-Oar-089580 Ovis aries 95.85 0.00e+00 820.00
IUUC-Ptr-090845 Pan troglodytes 95.97 0.00e+00 935.00
IUUC-Pan-092836 Papio anubis 95.99 0.00e+00 946.00
IUUC-Psi-093965 Pelodiscus sinensis 81.58 5.00e-56 208.00
IUUC-Pno-095052 Phaeosphaeria nodorum 46.91 4.00e-122 431.00
IUUC-Ppa-095432 Physcomitrella patens 58.64 2.00e-170 592.00
IUUC-Pfo-096963 Poecilia formosa 71.79 0.00e+00 702.00
IUUC-Pab-097716 Pongo abelii 92.57 0.00e+00 896.00
IUUC-Pop-099224 Populus trichocarpa 58.94 3.00e-171 594.00
IUUC-Pca-100682 Procavia capensis 92.11 0.00e+00 677.00
IUUC-Ppe-101819 Prunus persica 58.42 8.00e-169 586.00
IUUC-Pva-102338 Pteropus vampyrus 97.49 0.00e+00 726.00
IUUC-Pgr-103583 Puccinia graminis 55.12 6.00e-132 464.00
IUUC-Ptt-103737 Puccinia triticina 44.34 4.00e-99 355.00
IUUC-Pte-104150 Pyrenophora teres 49.89 3.00e-121 428.00
IUUC-Pyt-104606 Pyrenophora triticirepentis 49.89 3.00e-121 428.00
IUUC-Rno-105987 Rattus norvegicus 94.92 0.00e+00 934.00
IUUC-Sce-106315 Saccharomyces cerevisiae 47.66 4.00e-130 458.00
IUUC-Sha-107273 Sarcophilus harrisii 90.27 0.00e+00 905.00
IUUC-Sja-107677 Schizosaccharomyces japonicus 46.54 3.00e-118 419.00
IUUC-Spo-108092 Schizosaccharomyces pombe 48.28 2.00e-122 432.00
IUUC-Ssl-108442 Sclerotinia sclerotiorum 44.35 1.00e-115 409.00
IUUC-Smo-108855 Selaginella moellendorffii 55.65 1.00e-163 569.00
IUUC-Sit-110329 Setaria italica 59.31 3.00e-172 598.00
IUUC-Sly-111830 Solanum lycopersicum 59.53 1.00e-174 605.00
IUUC-Stu-112603 Solanum tuberosum 59.53 2.00e-174 605.00
IUUC-Sar-113504 Sorex araneus 90.85 1.00e-73 270.00
IUUC-Sbi-114560 Sorghum bicolor 58.24 6.00e-169 587.00
IUUC-Sre-115133 Sporisorium reilianum 42.64 2.00e-125 442.00
IUUC-Ssc-115903 Sus scrofa 95.99 0.00e+00 943.00
IUUC-Tgu-116798 Taeniopygia guttata 84.57 0.00e+00 855.00
IUUC-Tru-118361 Takifugu rubripes 78.32 0.00e+00 803.00
IUUC-Tsy-118849 Tarsius syrichta 96.60 0.00e+00 940.00
IUUC-Tni-120094 Tetraodon nigroviridis 78.48 0.00e+00 802.00
IUUC-Tca-121634 Theobroma cacao 58.30 3.00e-168 584.00
IUUC-Tre-122051 Trichoderma reesei 46.25 1.00e-119 423.00
IUUC-Tvi-122322 Trichoderma virens 47.50 1.00e-123 436.00
IUUC-Tae-125822 Triticum aestivum 58.24 1.00e-169 589.00
IUUC-Tur-126766 Triticum urartu 52.00 3.00e-161 561.00
IUUC-Tme-127175 Tuber melanosporum 50.95 2.00e-131 462.00
IUUC-Tbe-127779 Tupaia belangeri 95.78 0.00e+00 834.00
IUUC-Ttr-128224 Tursiops truncatus 92.06 0.00e+00 813.00
IUUC-Uma-129537 Ustilago maydis 42.50 5.00e-126 444.00
IUUC-Vda-129927 Verticillium dahliae 45.61 8.00e-112 397.00
IUUC-Vpa-130658 Vicugna pacos 84.71 0.00e+00 800.00
IUUC-Vvi-131659 Vitis vinifera 58.64 6.00e-171 593.00
IUUC-Xtr-132918 Xenopus tropicalis 77.05 0.00e+00 791.00
IUUC-Xma-133700 Xiphophorus maculatus 80.21 0.00e+00 815.00
IUUC-Yli-134478 Yarrowia lipolytica 49.90 2.00e-138 485.00
IUUC-Zma-135835 Zea mays 55.78 5.00e-166 577.00
Created Date 25-Jun-2017

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