iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Annotation

Single Nucleotide Polymorphisms (SNP)
dbSNP
mRNA Expression
GEO	ArrayExpress
DNA & RNA Element
TRANSFAC	miRNAMap	RAID2
Protein Expression/Proteomics
GPMDB

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
E3 adaptor/Cullin RING/APC_C/APC_C	23.03	1.80e-01	32.70	IUUC-Sce-106193

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Rattus norvegicus

Protein Sequence
(Fasta)

MPSYTVTVAT GSQWFAGTDD YIYLSLIGSA GCSEKHLLDK AFYNDFERGA VDSYDVTVDE 60
ELGEIYLVKI EKRKYWLHDD WYLKYITLKT PHGDYIEFPC YRWITGEGEI VLRDGCAKLA 120

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Nucleotide Sequence
(Fasta)

CGCCTGCTGG CCACTGTGGC AGGGAGCTGC CTTGAGTGAC AGAGTCAAGA ATCTGGTGGG 60
CTGCCACCTG AACTTCCCGG GCTCCTGCGC CCACGCCAGC AGCGCTCACT TCCCAGAGCC 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-0223--Dioxygenase
KW-0408--Iron
KW-0479--Metal-binding
KW-0560--Oxidoreductase
KW-1185--Reference proteome

Interpro

IPR000907--LipOase
IPR013819--LipOase_C
IPR020834--LipOase_CS
IPR020833--LipOase_Fe_BS
IPR001885--LipOase_mml
IPR001024--PLAT/LH2_dom

PROSITE

PS00711--LIPOXYGENASE_1
PS00081--LIPOXYGENASE_2
PS51393--LIPOXYGENASE_3
PS50095--PLAT

Pfam

PF00305--Lipoxygenase
PF01477--PLAT

PRINTS

PR00087--LIPOXYGENASE
PR00467--MAMLPOXGNASE

SMART

Gene Ontology

GO:0005829--C:cytosol
GO:0005615--C:extracellular space
GO:0005641--C:nuclear envelope lumen
GO:0016363--C:nuclear matrix
GO:0031965--C:nuclear membrane
GO:0005654--C:nucleoplasm
GO:0004051--F:arachidonate 5-lipoxygenase activity
GO:0005506--F:iron ion binding
GO:0019370--P:leukotriene biosynthetic process
GO:0002540--P:leukotriene production involved in inflammatory response

Orthology

Created Date

25-Jun-2017

Protein Fasta Sequence