iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Oga-089069

Ensembl Protein ID

ENSOGAP00000014152.2

UniProt Accession

H0XE16; H0XE16_OTOGA

Genbank Protein ID

ENSOGAP00000014152

Protein Name

Uncharacterized protein

Genbank Nucleotide ID

AAQR03127523

Gene Name

A2M

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
ENSOGAG00000015791.2	ENSOGAT00000015805.2	ENSOGAP00000014152.2

Status

Unreviewed

Classification

Family	Identity	E-Value	Score	Source Orthology
UBD/Alpha-Helix/CUE	37.74	1.30e+00	31.20	IUUC-Sce-106180

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Organism

Otolemur garnettii

Protein Sequence
(Fasta)

MGKNKLLHSS LALLLLVFLP TDASVSGKPH YMVLVPSLLH AETPEKGCVL LSHLNETVTV 60
SASLESLKGN RSLFTDLVVK KDLFHCVSFT VPKPSSNEEV MFLTVEVKGP TQKFSRRSTV 120

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Nucleotide Sequence
(Fasta)

ATGGGGAAGA ACAAACTCCT TCATTCAAGT CTTGCTCTTC TCCTCCTGGT CTTCCTGCCC 60
ACAGATGCCT CAGTCTCTGG AAAACCGTGA GTTCTACACA GAACCTGAAG CATGACTTGA 120

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Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0732--Signal

Interpro

IPR009048--A-macroglobulin_rcpt-bd
IPR011626--A2M_comp
IPR002890--A2M_N
IPR011625--A2M_N_2
IPR013783--Ig-like_fold
IPR014756--Ig_E-set
IPR001599--Macroglobln_a2
IPR019742--MacrogloblnA2_CS
IPR019565--MacrogloblnA2_thiol-ester-bond
IPR008930--Terpenoid_cyclase/PrenylTrfase
IPR010916--TonB_box_CS

PROSITE

PS00477--ALPHA_2_MACROGLOBULIN
PS00430--TONB_DEPENDENT_REC_1

Pfam

PF00207--A2M
PF07678--A2M_comp
PF01835--A2M_N
PF07703--A2M_N_2
PF07677--A2M_recep
PF10569--Thiol-ester_cl

SMART

SM01360--A2M
SM01359--A2M_N_2
SM01361--A2M_recep

Gene Ontology

GO:0072562--C:blood microparticle
GO:0070062--C:extracellular exosome
GO:0004867--F:serine-type endopeptidase inhibitor activity
GO:0001869--P:negative regulation of complement activation, lectin pathway
GO:0048863--P:stem cell differentiation

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Psi-093739	Pelodiscus sinensis	22.16	1.00e-47	186.00
IUUC-Pva-102340	Pteropus vampyrus	78.76	0.00e+00	2324.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence