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Basic Information Integrated Annotations
Tag Content
UUCD2 ID IUUC-Sce-106339
UUCD1 version UUC-SaC-00145
Ensembl Protein ID YDR364C
UniProt Accession P40968; D6VSZ3; Q06341; PRP17_YEAST
Genbank Protein ID AAA86875.1; AAB64800.1; DAA12203.1
Protein Name Pre-mRNA-processing factor 17; Cell division control protein 40
Genbank Nucleotide ID U17018; U28373; BK006938
Gene Name CDC40; PRP17; SLU4; XRS2; YDR364C; D9481.11
Ensembl Information
Ensembl Gene ID Ensembl Transcript ID Ensembl Protein ID
YDR364C YDR364C YDR364C
Annotation
mRNA Expression
GEOFFGED
Protein-protein Interaction
IIDiRefIndexHINTMentha
Protein 3D Structure
PDB
Post-translational Modifications (PTMs)
dbPAFPHOSIDABioGRID
Protein Expression/Proteomics
GPMDB
Status Unreviewed
Classification
Family E-Value Score Start End
E3 adaptor/Cullin RING/DCX/DWD 2.50e-24 82.8 204 239
Active Site
Position(s) Description Evidence
N/A N/A N/A
Domain Profile

   E3 adaptor/Cullin RING/DCX/DWD
   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDlrtgv 34
           gH+ ++ +l+f  d   ++s+s D ++k+WD+ tg+
   Q: 204  GHNKPIKALRFtEDcQSFLSSSFDRSVKIWDTETGK 239
           8**********955589***************9997 PP
   
Organism Saccharomyces cerevisiae
Functional Description
(View)

Functional Description


     Belongs to the CWC complex (or CEF1-associated complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least BUD13, BUD31, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2.
 Belongs to the CWC complex (or CEF1-associated complex), a spliceosome sub-complex reminiscent of a late-stage spliceosome composed of the U2, U5 and U6 snRNAs and at least BUD13, BUD31, BRR2, CDC40, CEF1, CLF1, CUS1, CWC2, CWC15, CWC21, CWC22, CWC23, CWC24, CWC25, CWC27, ECM2, HSH155, IST3, ISY1, LEA1, MSL1, NTC20, PRP8, PRP9, PRP11, PRP19, PRP21, PRP22, PRP45, PRP46, SLU7, SMB1, SMD1, SMD2, SMD3, SMX2, SMX3, SNT309, SNU114, SPP2, SYF1, SYF2, RSE1 and YJU2.
Protein Sequence
(Fasta)
MGLVDGYDTS SDSDLNFDEG KSVHEKKNGN LHEDTSYEPS SNNIHKRKSH FTKSELKRRR 60
KTRKGDGPWG SWSSSDDETS QASETQKEDQ DIFVHALAED NLDSEQIEVE EVSHFYGKSE 120
It may take some time, please wait.

Protein Fasta Sequence


>IUUC-Sce-106339|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Nucleotide Sequence
(Fasta)
ATGGGTTTAG TAGACGGTTA TGACACAAGC TCAGACTCTG ATTTGAACTT CGACGAAGGC 60
AAATCTGTTC ATGAAAAGAA AAATGGTAAT TTGCATGAAG ATACTTCGTA TGAACCTTCT 120
It may take some time, please wait.

Nucleotide Fasta Sequence


>IUUC-Sce-106339|E3,WD_repeat|Saccharomyces cerevisiae
Please wait for a moment...
Sequence Source Ensembl
Keyword

KW-0002--3D-structure
KW-0181--Complete proteome
KW-0507--mRNA processing
KW-0508--mRNA splicing
KW-0539--Nucleus
KW-1185--Reference proteome
KW-0677--Repeat
KW-0747--Spliceosome
KW-0853--WD repeat
Interpro

IPR020472--G-protein_beta_WD-40_rep
IPR032847--PRPF17
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom
PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION
Pfam

PF00400--WD40
PRINTS

PR00320--GPROTEINBRPT
SMART

SM00320--WD40
Gene Ontology

GO:0071013--C:catalytic step 2 spliceosome
GO:0034399--C:nuclear periphery
GO:0005681--C:spliceosomal complex
GO:0000350--P:generation of catalytic spliceosome for second transesterification step
GO:0000389--P:mRNA 3'-splice site recognition
GO:0000348--P:mRNA branch site recognition
KEGG sce:YDR364C
Orthology
iUUCD ID Species Identity E-value Score
IUUC-Ata-000473 Aegilops tauschii 39.00 2.00e-74 271.00
IUUC-Aml-002243 Ailuropoda melanoleuca 36.96 4.00e-46 176.00
IUUC-Atr-002612 Amborella trichopoda 36.86 4.00e-73 267.00
IUUC-Apl-003885 Anas platyrhynchos 37.53 9.00e-77 278.00
IUUC-Aca-004854 Anolis carolinensis 30.52 1.00e-45 175.00
IUUC-Aly-006158 Arabidopsis lyrata 37.39 3.00e-74 270.00
IUUC-Ath-007474 Arabidopsis thaliana 37.54 4.00e-74 270.00
IUUC-Ago-007726 Ashbya gossypii 51.95 4.00e-129 452.00
IUUC-Acl-008220 Aspergillus clavatus 41.46 7.00e-80 289.00
IUUC-Afl-008473 Aspergillus flavus 37.67 4.00e-81 293.00
IUUC-Afu-008773 Aspergillus fumigatus 35.08 1.00e-79 288.00
IUUC-Ani-009323 Aspergillus nidulans 40.97 3.00e-70 257.00
IUUC-Ang-009851 Aspergillus niger 40.97 1.00e-78 285.00
IUUC-Aor-009950 Aspergillus oryzae 37.67 4.00e-81 293.00
IUUC-Ate-010372 Aspergillus terreus 42.18 2.00e-81 294.00
IUUC-Ame-011660 Astyanax mexicanus 38.01 4.00e-80 290.00
IUUC-Bgr-012230 Blumeria graminis 36.92 4.00e-86 309.00
IUUC-Bta-012568 Bos taurus 38.36 3.00e-76 277.00
IUUC-Bci-013646 Botrytis cinerea 40.18 1.00e-78 284.00
IUUC-Bdi-014867 Brachypodium distachyon 39.00 9.00e-76 275.00
IUUC-Bol-015695 Brassica oleracea 36.81 2.00e-73 267.00
IUUC-Bra-017923 Brassica rapa 34.64 1.00e-73 268.00
IUUC-Cel-018535 Caenorhabditis elegans 38.44 7.00e-79 285.00
IUUC-Cja-019071 Callithrix jacchus 38.36 3.00e-76 277.00
IUUC-Cfa-020559 Canis familiaris 38.36 4.00e-76 276.00
IUUC-Cpo-022356 Cavia porcellus 38.36 4.00e-76 276.00
IUUC-Cre-022594 Chlamydomonas reinhardtii 30.09 1.00e-41 160.00
IUUC-Csa-023125 Chlorocebus sabaeus 38.36 2.00e-76 277.00
IUUC-Cho-024676 Choloepus hoffmanni 37.41 3.00e-78 283.00
IUUC-Cin-025229 Ciona intestinalis 35.73 1.00e-79 288.00
IUUC-Csv-025868 Ciona savignyi 40.66 2.00e-22 94.70
IUUC-Cgl-026739 Colletotrichum gloeosporioides 37.93 4.00e-71 259.00
IUUC-Cne-026885 Cryptococcus neoformans 36.66 4.00e-68 250.00
IUUC-Dre-027631 Danio rerio 36.83 5.00e-79 286.00
IUUC-Dno-029815 Dasypus novemcinctus 40.35 1.00e-72 265.00
IUUC-Dor-031143 Dipodomys ordii 40.29 3.00e-72 264.00
IUUC-Dse-031520 Dothistroma septosporum 40.27 8.00e-78 282.00
IUUC-Dme-032050 Drosophila melanogaster 35.89 2.00e-77 280.00
IUUC-Ete-032866 Echinops telfairi 36.57 1.00e-72 265.00
IUUC-Eca-033384 Equus caballus 38.36 6.00e-75 273.00
IUUC-Eeu-034471 Erinaceus europaeus 29.68 3.00e-46 177.00
IUUC-Fca-035727 Felis catus 38.36 3.00e-76 277.00
IUUC-Fal-036774 Ficedula albicollis 36.39 5.00e-77 279.00
IUUC-Fox-037951 Fusarium oxysporum 40.52 3.00e-79 287.00
IUUC-Fso-038287 Fusarium solani 41.40 3.00e-79 287.00
IUUC-Gmo-039670 Gadus morhua 37.34 1.00e-80 292.00
IUUC-Ggr-039764 Gaeumannomyces graminis 34.68 8.00e-79 285.00
IUUC-Gga-040293 Gallus gallus 38.11 1.00e-78 285.00
IUUC-Gac-042159 Gasterosteus aculeatus 37.34 9.00e-80 289.00
IUUC-Gma-044299 Glycine max 38.26 5.00e-75 273.00
IUUC-Ggo-044864 Gorilla gorilla 38.11 1.00e-75 275.00
IUUC-Hsa-046602 Homo sapiens 38.11 1.00e-75 275.00
IUUC-Hvu-047431 Hordeum vulgare 27.56 5.00e-32 129.00
IUUC-Itr-047985 Ictidomys tridecemlineatus 38.36 2.00e-76 276.00
IUUC-Kpa-049318 Komagataella pastoris 44.48 4.00e-87 313.00
IUUC-Lch-049796 Latimeria chalumnae 34.53 4.00e-65 240.00
IUUC-Lpe-051153 Leersia perrieri 38.71 2.00e-74 271.00
IUUC-Loc-052467 Lepisosteus oculatus 36.43 2.00e-79 287.00
IUUC-Lma-053107 Leptosphaeria maculans 39.27 7.00e-75 272.00
IUUC-Laf-053787 Loxodonta africana 38.36 3.00e-78 283.00
IUUC-Mcc-055706 Macaca mulatta 38.36 3.00e-76 277.00
IUUC-Meu-056757 Macropus eugenii 38.39 9.00e-63 232.00
IUUC-Mor-057079 Magnaporthe oryzae 39.89 5.00e-81 293.00
IUUC-Mpo-057533 Magnaporthe poae 39.07 3.00e-80 290.00
IUUC-Mtr-057950 Medicago truncatula 37.39 3.00e-74 270.00
IUUC-Mla-058910 Melampsora laricipopulina 33.18 4.00e-68 250.00
IUUC-Mga-059366 Meleagris gallopavo 38.11 1.00e-78 285.00
IUUC-Mvi-060349 Microbotryum violaceum 41.62 1.00e-78 285.00
IUUC-Mmr-061209 Microcebus murinus 38.36 6.00e-78 283.00
IUUC-Mdo-062118 Monodelphis domestica 37.05 3.00e-77 280.00
IUUC-Mmu-063173 Mus musculus 38.36 4.00e-76 276.00
IUUC-Mac-065109 Musa acuminata 37.86 3.00e-73 267.00
IUUC-Mpu-066659 Mustela putorius furo 38.36 3.00e-76 277.00
IUUC-Mlu-067029 Myotis lucifugus 38.36 6.00e-76 276.00
IUUC-Nfi-068334 Neosartorya fischeri 34.87 5.00e-80 289.00
IUUC-Ncr-068675 Neurospora crassa 40.06 4.00e-71 260.00
IUUC-Nle-070113 Nomascus leucogenys 38.36 3.00e-76 277.00
IUUC-Opr-070685 Ochotona princeps 40.23 3.00e-75 273.00
IUUC-Ont-071680 Oreochromis niloticus 36.57 4.00e-77 280.00
IUUC-Oan-073573 Ornithorhynchus anatinus 37.60 2.00e-75 274.00
IUUC-Ocu-074074 Oryctolagus cuniculus 38.62 9.00e-79 285.00
IUUC-Oba-075625 Oryza barthii 38.42 3.00e-74 270.00
IUUC-Obr-076510 Oryza brachyantha 38.26 3.00e-74 270.00
IUUC-Ogl-077275 Oryza glaberrima 38.42 3.00e-74 270.00
IUUC-Ogu-078563 Oryza glumaepatula 38.42 3.00e-74 270.00
IUUC-Oin-079898 Oryza indica 38.42 2.00e-74 271.00
IUUC-Olo-081080 Oryza longistaminata 38.42 1.00e-74 271.00
IUUC-Ome-081794 Oryza meridionalis 26.87 4.00e-23 100.00
IUUC-Oni-083121 Oryza nivara 38.42 3.00e-74 270.00
IUUC-Opu-083329 Oryza punctata 38.42 3.00e-74 270.00
IUUC-Oru-084807 Oryza rufipogon 38.78 7.00e-66 242.00
IUUC-Osa-086039 Oryza sativa 38.26 3.00e-74 270.00
IUUC-Ola-087149 Oryzias latipes 37.69 4.00e-80 290.00
IUUC-Olu-087627 Ostreococcus lucimarinus 36.23 5.00e-66 243.00
IUUC-Oga-088359 Otolemur garnettii 38.36 4.00e-76 276.00
IUUC-Oar-089390 Ovis aries 38.36 7.00e-76 276.00
IUUC-Ptr-090894 Pan troglodytes 38.11 1.00e-75 275.00
IUUC-Pan-092476 Papio anubis 38.36 3.00e-76 277.00
IUUC-Psi-093527 Pelodiscus sinensis 36.69 1.00e-70 258.00
IUUC-Pno-094771 Phaeosphaeria nodorum 39.71 8.00e-76 275.00
IUUC-Ppa-095386 Physcomitrella patens 37.27 5.00e-78 283.00
IUUC-Pfo-096139 Poecilia formosa 37.60 1.00e-79 288.00
IUUC-Pab-097838 Pongo abelii 37.65 1.00e-63 235.00
IUUC-Pop-098945 Populus trichocarpa 37.32 7.00e-74 269.00
IUUC-Pca-100876 Procavia capensis 35.92 3.00e-60 224.00
IUUC-Ppe-101777 Prunus persica 38.37 6.00e-74 269.00
IUUC-Pva-102418 Pteropus vampyrus 38.36 4.00e-76 276.00
IUUC-Pgr-103456 Puccinia graminis 35.31 4.00e-78 283.00
IUUC-Ptt-103731 Puccinia triticina 34.96 3.00e-72 263.00
IUUC-Pte-104386 Pyrenophora teres 40.29 6.00e-77 279.00
IUUC-Pyt-104560 Pyrenophora triticirepentis 40.46 9.00e-77 278.00
IUUC-Rno-105694 Rattus norvegicus 38.36 4.00e-76 276.00
IUUC-Sha-106709 Sarcophilus harrisii 37.97 5.00e-77 280.00
IUUC-Sja-107817 Schizosaccharomyces japonicus 42.32 7.00e-82 296.00
IUUC-Spo-108331 Schizosaccharomyces pombe 41.08 2.00e-83 300.00
IUUC-Ssl-108530 Sclerotinia sclerotiorum 41.22 1.00e-70 258.00
IUUC-Smo-108778 Selaginella moellendorffii 37.24 1.00e-68 251.00
IUUC-Sit-110446 Setaria italica 37.97 8.00e-73 265.00
IUUC-Sly-111330 Solanum lycopersicum 38.19 4.00e-73 266.00
IUUC-Stu-112610 Solanum tuberosum 38.04 3.00e-73 267.00
IUUC-Sar-113065 Sorex araneus 35.09 2.00e-24 105.00
IUUC-Sbi-114005 Sorghum bicolor 38.15 2.00e-73 268.00
IUUC-Sre-114988 Sporisorium reilianum 34.65 4.00e-82 296.00
IUUC-Ssc-115760 Sus scrofa 38.36 3.00e-76 277.00
IUUC-Tgu-116493 Taeniopygia guttata 36.56 1.00e-78 285.00
IUUC-Tru-118489 Takifugu rubripes 37.44 5.00e-77 280.00
IUUC-Tsy-119332 Tarsius syrichta 38.36 5.00e-78 283.00
IUUC-Tni-120202 Tetraodon nigroviridis 35.29 9.00e-69 252.00
IUUC-Tca-121429 Theobroma cacao 36.52 2.00e-73 268.00
IUUC-Tre-122162 Trichoderma reesei 41.38 8.00e-80 288.00
IUUC-Tvi-122500 Trichoderma virens 40.80 2.00e-79 287.00
IUUC-Tae-125557 Triticum aestivum 38.84 2.00e-74 271.00
IUUC-Tur-126554 Triticum urartu 38.95 6.00e-75 273.00
IUUC-Tme-126919 Tuber melanosporum 36.32 6.00e-77 279.00
IUUC-Tbe-127968 Tupaia belangeri 36.32 2.00e-71 261.00
IUUC-Ttr-129215 Tursiops truncatus 38.21 2.00e-75 274.00
IUUC-Uma-129622 Ustilago maydis 38.87 5.00e-81 293.00
IUUC-Vda-129750 Verticillium dahliae 41.09 2.00e-82 298.00
IUUC-Vpa-130617 Vicugna pacos 38.36 3.00e-76 276.00
IUUC-Vvi-131238 Vitis vinifera 36.68 5.00e-74 270.00
IUUC-Xtr-131865 Xenopus tropicalis 37.82 7.00e-79 285.00
IUUC-Xma-133627 Xiphophorus maculatus 37.97 2.00e-79 287.00
IUUC-Yli-134390 Yarrowia lipolytica 39.72 1.00e-81 295.00
IUUC-Zma-135925 Zea mays 38.14 5.00e-69 253.00
Created Date 25-Jun-2017

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