iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

Protein
Gene
Annotation
Classification
Domain Profile
Function
Protein Sequence
Nucleotide Sequence
Keyword
GO
Orthology
TOP

Tag

Content

iUUCD ID

IUUC-Sly-111560

Ensembl Protein ID

Solyc12g056490.1.1

UniProt Accession

K4DFY0; K4DFY0_SOLLC

Protein Name

Uncharacterized protein

Ensembl Information

Ensembl Gene ID	Ensembl Transcript ID	Ensembl Protein ID
Solyc12g056490.1	Solyc12g056490.1.1	Solyc12g056490.1.1

Status

Unreviewed

Classification

Family	E-Value	Score	Start	End
E3 adaptor/Cullin RING/APC_C/CDC20	3.60e-143	477.1	162	463
E3 adaptor/Cullin RING/DCX/DWD	6.00e-27	93.3	296	327
UBD/Beta-Prp	7.00e-43	147.6	289	457

Active Site

Position(s)	Description	Evidence
N/A	N/A	N/A

Domain Profile

E3 adaptor/Cullin RING/APC_C/CDC20

   S: 1    pekvldapelrddfylnLldWssknvlavaLgssvylwsaktgdvskladleekdlvtsvswieegtllavGtkkgeveiyDveekkkvrt 91
           p+kvldap l+ddfylnL+dWss+nvlav+Lgssvylw a++g+v+kl+dle++d vtsv w ++gt+lavGt++g+v+++D+++ k +rt
   Q: 162  PYKVLDAPALQDDFYLNLVDWSSQNVLAVGLGSSVYLWHASNGKVVKLCDLENDDNVTSVGWAQRGTHLAVGTSNGKVQLWDASHGKMTRT 252
           79***************************************************************************************** PP
   S: 92   ltghsarvgaLsWnaevlssGsrdgeilhrdvrvkelklstlqahaqevCGlkwnedaklLasGGnDnsvsvwdasssePlkkfkehkaav 182
           ++gh  rvgaLsW + +lssGsrd++il+rd+r+++  +s+l++h++evCGlkw+ d+++LasGGnDn + vw+++s++P+ k+ eh+aav
   Q: 253  MEGHRLRVGALSWSSSQLSSGSRDKSILQRDIRAQDDYVSKLSGHKSEVCGLKWSPDSRELASGGNDNRLFVWNNHSTQPILKYCEHTAAV 343
           ******************************************************************************************* PP
   S: 183  kaiawsPwqkslLasGGGtaDrcikfwntltgalleeidtgsqvcsllwskkskelvsthGfaenkitlwkypslskvaelkgheaRvlsl 273
           kaiawsP+ ++lLasGGGtaDrci+fwnt+t + l+++dtgsqvc+l+wsk+++elvsthG+++n+i+lw+yp+++kva+l+gh++Rvl+l
   Q: 344  KAIAWSPHLHGLLASGGGTADRCIRFWNTTTNTHLSCMDTGSQVCNLVWSKNANELVSTHGYSQNQIILWRYPTMTKVATLTGHTYRVLYL 434
           ******************************************************************************************* PP
   S: 274  alspdgeaivtaagDetlrfwklfdkkka 302
           a+spdg+ ivt+agDetlrfw++f + k+
   Q: 435  AISPDGQMIVTGAGDETLRFWNVFPSPKS 463
           ************************87665 PP

E3 adaptor/Cullin RING/DCX/DWD

   S: 1    gHtdsvtclaf.sd.tllvsGsdDgtikvWDl 30
           gH+++v++l++ +d + l+sG++D+ + vW+ 
   Q: 296  GHKSEVCGLKWsPDsRELASGGNDNRLFVWNN 327
           8***********999***************96 PP

UBD/Beta-Prp

   S: 85   kcvhtlkghedsvlslsfspsgdklvsGshdrtirvwdletgqcleetlsghdgvvncvvvhpdg.nllvsG..slDrtvrlWdlktgkll 172
           ++v++l+gh+++v+ l++sp++  l+sG++d+ + vw+ ++ q +     +h+++v  ++++p    ll+sG  ++Dr++r+W+  t++ l
   Q: 289  DYVSKLSGHKSEVCGLKWSPDSRELASGGNDNRLFVWNNHSTQPIL-KYCEHTAAVKAIAWSPHLhGLLASGggTADRCIRFWNTTTNTHL 378
           4556666666666666666666666666666666666666666666.55666666666666666666666642245666666666666666 PP
   S: 173  rtltgghtdsvyslsfdsngkelvs..gsldgtvklwdlqtgecvrtlnghtdnvksvrfspnderlvsgssDgsiriWdl 251
             +     ++v  l +++n +elvs  g   ++++lw + t + v tl+ght  v+ ++ sp+++ +v+g+ D+++r+W++
   Q: 379  SCMD--TGSQVCNLVWSKNANELVSthGYSQNQIILWRYPTMTKVATLTGHTYRVLYLAISPDGQMIVTGAGDETLRFWNV 457
           6663..356666666666666666544556666666666666666666666666666666666666666666666666653 PP

Organism

Solanum lycopersicum

Protein Sequence
(Fasta)

MENPSSNSME PQTPFDPNSN MNPKTPSKTN LIPGFNSYHP SPSRSIYSDR FIPSRTSSNF 60
ALFGLPLSPK SSNTEDSNSG YTSLLRTALF GPDSGNVVNP VTPEKGVRGN GRNLKRPNCN 120

It may take some time, please wait.

Nucleotide Sequence
(Fasta)

ATGGAGAATC CAAGCTCGAA TTCCATGGAA CCTCAAACAC CCTTTGATCC CAATTCCAAT 60
ATGAACCCCA AAACTCCATC AAAGACTAAT TTAATCCCGG GTTTCAATTC ATACCATCCT 120

It may take some time, please wait.

Sequence Source

Ensembl

Keyword

KW-0181--Complete proteome
KW-1185--Reference proteome
KW-0677--Repeat
KW-0853--WD repeat

Interpro

IPR024977--Apc4_WD40_dom
IPR033010--Cdc20/Fizzy
IPR015943--WD40/YVTN_repeat-like_dom
IPR001680--WD40_repeat
IPR019775--WD40_repeat_CS
IPR017986--WD40_repeat_dom

PROSITE

PS00678--WD_REPEATS_1
PS50082--WD_REPEATS_2
PS50294--WD_REPEATS_REGION

Pfam

PF12894--ANAPC4_WD40
PF00400--WD40

SMART

SM00320--WD40

Gene Ontology

GO:0097027--F:ubiquitin-protein transferase activator activity
GO:1904668--P:positive regulation of ubiquitin protein ligase activity

KEGG

sly:101257937

Orthology

iUUCD ID	Species	Identity	E-value	Score
IUUC-Acl-008269	Aspergillus clavatus	49.70	5.00e-127	447.00
IUUC-Afu-008829	Aspergillus fumigatus	49.69	1.00e-126	446.00
IUUC-Kpa-049239	Komagataella pastoris	44.71	5.00e-118	417.00
IUUC-Mor-057113	Magnaporthe oryzae	49.79	1.00e-121	429.00
IUUC-Nfi-068536	Neosartorya fischeri	49.69	1.00e-126	446.00
IUUC-Sce-106240	Saccharomyces cerevisiae	47.95	9.00e-98	350.00
IUUC-Ssl-108391	Sclerotinia sclerotiorum	48.71	3.00e-118	418.00
IUUC-Stu-112835	Solanum tuberosum	96.71	0.00e+00	871.00

Created Date

25-Jun-2017

Protein Fasta Sequence

Nucleotide Fasta Sequence